HARADA Ryuichi 原田龍一

… Alternative Names

Ryuichi Harada 原田龍一

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Researcher Number	60735455
Other IDs
Affiliation (Current)	2025: 東北医科薬科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 東北医科薬科大学, 医学部, 助教 2016 – 2023: 東北大学, 医学系研究科, 助教 2015: 東北大学, 加齢医学研究所, 特別研究員(PD)
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related / Radiation science Except Principal Investigator Basic Section 52040:Radiological sciences-related / Medium-sized Section 52:General internal medicine and related fields / Basic Section 48030:Pharmacology-related / Applied pharmacology
Keywords	Principal Investigator 放射性医薬品 / PETプローブ / アストロサイト / アルツハイマー病 / ApoE / 分子イメージング / 代謝 / タウ / PET / 神経機能画像学 … More / 放射性医薬品・造影剤 / 神経機能画像 / 神経変性疾患 / イメージング / 造影剤 … More Except Principal Investigator PET / アルツハイマー病 / 分子イメージング / モノアミン酸化酵素B / 過眠症 / ナルコレプシー / 阻害薬 / ヒスタミン代謝酵素 / ヒスタミン神経系 / 新規ナルコレプシー治療薬 / ヒスタミン代謝酵素阻害薬 / ヒスタミンN-メチル転移酵素 / ヒスタミン分解酵素 / ヒスタミン / タウ / 早期診断 / マルチバレント / アストログリオーシス / モノアミン酸化酵素B (MAO-B) / パーキンソン病 / 全身集積 / ポジトロン断層法（PET） / [18F]SMBT-1 / MAO阻害薬 / 腫瘍疾患 / 変性性神経疾患 / モノアミン酸化酵素(MAO-B) / ポジトロン断層法 (PET) / アストロサイト / バイオマーカー / 神経炎症 / 濃縮法 / 標識反応 / 自動合成 / PETプローブ / フッ素-18 / マイクロスケール合成 / fluorine-18 / BBB透過性ペプチド / 神経疾患 / Fluorine-18 / タンパク質プローブ / グリオーシス / ミスフォールディング / 神経変性疾患 / ミエリン化 / 髄鞘化 / クリック / アミロイドβ / ミエリン / プリン受容体 / ミクログリア / タンパク質 / 放射性医薬品 Less

Research for imaging of ApoE proteinopathyPrincipal Investigator
- Principal Investigator
  
  原田龍一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tohoku University
Elucidation of the pathophysiology of Alzheimer's disease by a novel tau-specific PET tracer, [F18]SNFT-1
- Principal Investigator
  
  金田朋洋
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tohoku University
神経炎症を生体画像化する新規画像バイオマーカーの開発研究
- Principal Investigator
  
  岡村信行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Tohoku Medical and Pharmaceutical University
Development of multivalent PET tracers for the early diagnosis of Alzheimer's disease
- Principal Investigator
  
  加藤孝一
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center of Neurology and Psychiatry
Elucidation of important research issues that remain in histamine pharmacology
- Principal Investigator
  
  谷内一彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Tohoku University
Quantitative MAO-B imaging of human brain and whole-body organs using [18F]SMBT-1 PET
- Principal Investigator
  
  田代学
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tohoku University
Reverse translational research for imaging astrogliosisPrincipal Investigator
- Principal Investigator
  
  Harada Ryuichi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
  Tohoku University
Development of Fluorine-18 labeled protein PET molecular probes for the application to neurological diseases
- Principal Investigator
  
  Yanai Kazuhiko
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Tohoku University
Development of efficient microscale automated module for radiosynthesis of 18F-labeled probes
- Principal Investigator
  
  Iwata Ren
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tohoku University
Development of PET tracers for the imaging of microglial cells and their activities
- Principal Investigator
  
  KATO KOICHI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center of Neurology and Psychiatry
Development of protein-specific PET molecular imaging in neurodegenerative disorders
- Principal Investigator
  
  Yanai Kazuhiko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Tohoku University
Development of PET probes for visualization of neurodegenerative processPrincipal Investigator
- Principal Investigator
  
  HARADA RYUICHI
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tohoku University
Development of a novel labeling method for affibody by F-18 labeled amino acid and a cell-free protein synthesis system
- Principal Investigator
  
  Yanai Kazuhiko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
Comparative study of tau imaging tracersPrincipal Investigator
- Principal Investigator
  
  Ryuichi Harada
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Tohoku University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Patent

[Journal Article] 4.Preclinical Characterization of the Tau PET Tracer [18F]SNFT-1: Comparison of Tau PET Tracers.2023
- Author(s)
  Harada R, Lerdsirisuk P, Shimizu Y, Yokoyama Y, Du Y, Kudo K, Ezura M, Ishikawa Y, Iwata R, Shidahara M, Ishiki A, Kikuchi A, Hatano Y, Ishihara T, Onodera O, Iwasaki Y, Yoshida M, Taki Y, Arai H, Kudo Y, Yanai K, Furumoto S, Okamura N.
- Journal Title
  
  J Nucl Med
  
  Volume: 64 Issue: 9 Pages: 1495-1501
- DOI
  10.2967/jnumed.123.265593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15647, KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-20K07879, KAKENHI-PROJECT-23K06947, KAKENHI-PROJECT-23K07069
[Journal Article] A Novel Near-Infrared Fluorescence Probe THK-565 Enables In Vivo Detection of Amyloid Deposits in Alzheimer’s Disease Mouse Model2023
- Author(s)
  Naganuma Fumito、Murata Daiki、Inoue Marie、Maehori Yuri、Harada Ryuichi、Furumoto Shozo、Kudo Yukitsuka、Nakamura Tadaho、Okamura Nobuyuki
- Journal Title
  
  Molecular Imaging and Biology
  
  Volume: 25 Issue: 6 Pages: 1115-1124
- DOI
  10.1007/s11307-023-01843-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-22K07373, KAKENHI-PROJECT-23K07069, KAKENHI-PROJECT-23K08342, KAKENHI-PROJECT-23K24070
[Journal Article] In vivo [18F]THK-5351 imaging detected reactive astrogliosis in argyrophilic grain disease with comorbid pathology: A clinicopathological study2023
- Author(s)
  Ryota Kobayashi , Tadaho Nakamura, Fumito Naganuma, Ryuichi Harada, Daichi Morioka, Masafumi Kanoto, Shozo Furumoto, Yukitsuka Kudo, Takanobu Kabasawa, Koichi Otani, Mitsuru Futakuchi , Shinobu Kawakatsu, Nobuyuki Okamura
- Journal Title
  
  J Neuropathol Exp Neurol .
  
  Volume: - Issue: 5 Pages: 427-437
- DOI
  10.1093/jnen/nlad018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-22K07373, KAKENHI-PROJECT-22K07552, KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-20K07922, KAKENHI-PROJECT-20K09204, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-23K06646, KAKENHI-PROJECT-23K07129, KAKENHI-PROJECT-20K07619
[Journal Article] Evaluation of 18F labeled glial fibrillary acidic protein binding nanobody and its brain shuttle peptide fusion proteins using a neuroinflammation rat model2023
- Author(s)
  Morito Takahiro、Harada Ryuichi、Iwata Ren、Ishikawa Yoichi、Okamura Nobuyuki、Kudo Yukitsuka、Furumoto Shozo、Yanai Kazuhiko、Tashiro Manabu
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 6 Pages: 0287047-0287047
- DOI
  10.1371/journal.pone.0287047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-23K07069, KAKENHI-PROJECT-21K19320, KAKENHI-PROJECT-23K21420, KAKENHI-PROJECT-23K24070
[Journal Article] Assessing reactive astrogliosis with 18F-SMBT-1 across the Alzheimer’s disease spectrum2022
- Author(s)
  Villemagne Victor L、Harada Ryuichi、Dore Vincent、Furumoto Shozo、Mulligan Rachel、Kudo Yukitsuka、Burnham Samantha、Krishnadas Natasha、Bourgeat Pierrick、Xia Ying、Laws Simon、Bozinovski Svetlana、Huang Kun、Ikonomovic Milos D、Fripp Jurgen、Yanai Kazuhiko、Okamura Nobuyuki、Rowe Christopher C
- Journal Title
  
  Journal of Nuclear Medicine
  
  Volume: - Issue: 10 Pages: 1560-1569
- DOI
  10.2967/jnumed.121.263255
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-18H02771
[Journal Article] Imaging of Reactive Astrogliosis by Positron Emission Tomography2022
- Author(s)
  Harada Ryuichi、Furumoto Shozo、Kudo Yukitsuka、Yanai Kazuhiko、Villemagne Victor L.、Okamura Nobuyuki
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 16 Pages: 807435-807435
- DOI
  10.3389/fnins.2022.807435
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-23K21420, KAKENHI-PROJECT-23K24070
[Journal Article] The Role of Chirality of [18F]SMBT-1 in Imaging of Monoamine Oxidase-B2022
- Author(s)
 Harada Ryuichi、Shimizu Yuki、Du Yiqing、Ishikawa Yoichi、Iwata Ren、Kudo Yukitsuka、Yanai Kazuhiko、Okamura Nobuyuki、Furumoto Shozo
- Journal Title
 
 ACS Chemical Neuroscience
 
 Volume: 13 Issue: 3 Pages: 322-329
- DOI
 10.1021/acschemneuro.1c00655
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-20H03614, KAKENHI-PROJECT-23K21420
[Journal Article] First-in-human evaluation of 18F-SMBT-1, a novel 18F-labeled MAO-B PET tracer for imaging reactive astrogliosis2022
- Author(s)
 Villemagne Victor L、Harada Ryuichi、Dore Vincent、Furumoto Shozo、Mulligan Rachel、Kudo Yukitsuka、Burnham Samantha、Krishnadas Natasha、Bozinovski Svetlana、Huang Kun、Lopresti Brian J、Yanai Kazuhiko、Rowe Christopher C、Okamura Nobuyuki
- Journal Title
 
 Journal of Nuclear Medicine
 
 Volume: - Issue: 10 Pages: 1551-1559
- DOI
 10.2967/jnumed.121.263254
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-18H02771
[Journal Article] Synthesis and pharmacokinetic characterisation of a fluorine-18 labelled brain shuttle peptide fusion dimeric affibody2021
- Author(s)
  Morito Takahiro、Harada Ryuichi、Iwata Ren、Du Yiqing、Okamura Nobuyuki、Kudo Yukitsuka、Yanai Kazuhiko
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 2588-2588
- DOI
  10.1038/s41598-021-82037-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21564, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-20H03614, KAKENHI-PROJECT-18H02771
[Journal Article] 18F-THK5351 PET imaging in neurodegenerative tauopathies2021
- Author(s)
  Ezura M, Kikuchi A, Okamura N, Ishiki A, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Yoshida S, Kobayashi J, Kobayashi M, Tano O, Ishiyama S, Nakamura T, Nakashima I, Mugikura S, Iwata R, Taki Y, Furukawa K, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M
- Journal Title
  
  Front Aging Neurosci
  
  Volume: 13 Pages: 761010-761010
- DOI
  10.3389/fnagi.2021.761010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-20H03614, KAKENHI-PROJECT-20K07830, KAKENHI-PROJECT-20K07862, KAKENHI-PROJECT-20K07879, KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-21K19320, KAKENHI-PROJECT-18K15357, KAKENHI-PROJECT-19KK0212
[Journal Article] Synthesis and evaluation of 2-pyrrolopyridinylquinoline derivatives as selective tau PET tracers for the diagnosis of Alzheimer's disease2021
- Author(s)
  Lerdsirisuk Pradith、Harada Ryuichi、Hayakawa Yoshimi、Shimizu Yuki、Ishikawa Yoichi、Iwata Ren、Kudo Yukitsuka、Okamura Nobuyuki、Furumoto Shozo
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 93 Pages: 11-18
- DOI
  10.1016/j.nucmedbio.2020.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-20H03614, KAKENHI-PROJECT-18H02771
[Journal Article] タンパク質医薬品開発のためのポジトロン放出核種標識タンパク質2020
- Author(s)
  原田龍一、盛戸貴裕、谷内一彦
- Journal Title
  
  日本薬理学会雑誌
  
  Volume: 155 Pages: 159-163
- NAID
  130007839036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0212
[Journal Article] A concentration-based microscale method for 18F-nucleophilic substitutions and its testing on the one-pot radiosynthesis of [18F]FET and [18F]fallypride2020
- Author(s)
  Iwata Ren、Terasaki Kazunori、Ishikawa Yoichi、Harada Ryuichi、Furumoto Shozo、Yanai Kazuhiko、Pascali Claudio
- Journal Title
  
  Applied Radiation and Isotopes
  
  Volume: 166 Pages: 109361-109361
- DOI
  10.1016/j.apradiso.2020.109361
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03614
[Journal Article] 18F-SMBT-1: A Selective and Reversible PET Tracer for Monoamine Oxidase-B Imaging2020
- Author(s)
  Harada Ryuichi、Hayakawa Yoshimi、Ezura Michinori、Lerdsirisuk Pradith、Du Yiqing、Ishikawa Yoichi、Iwata Ren、Shidahara Miho、Ishiki Aiko、Kikuchi Akio、Arai Hiroyuki、Kudo Yukitsuka、Yanai Kazuhiko、Furumoto Shozo、Okamura Nobuyuki
- Journal Title
  
  Journal of Nuclear Medicine
  
  Volume: 62 Issue: 2 Pages: 253-258
- DOI
  10.2967/jnumed.120.244400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-18K15357, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-20H03614, KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-20K07879
[Journal Article] ポジトロン放出核種標識タンパク質の新規合成方法の開発2019
- Author(s)
  原田龍一、盛戸貴裕、谷内一彦
- Journal Title
  
  バイオインダストリー
  
  Volume: 36 Pages: 46-54
- Data Source
  KAKENHI-PROJECT-19KK0212
[Journal Article] Characterization of the binding of tau imaging ligands to melanin-containing cells: putative off-target-binding site2019
- Author(s)
  Tago Tetsuro、Toyohara Jun、Harada Ryuichi、Furumoto Shozo、Okamura Nubuyuki、Kudo Yukitsuka、Takahashi-Fujigasaki Junko、Murayama Shigeo、Ishii Kenji
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 33 Issue: 6 Pages: 1-8
- DOI
  10.1007/s12149-019-01344-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09813, KAKENHI-PROJECT-18K15655, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-18K15538, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-18H02771
[Journal Article] Brain histamine H1 receptor occupancy after oral administration of desloratadine and loratadine2019
- Author(s)
  Nakamura Tadaho、Hiraoka Kotaro、Harada Ryuichi、Matsuzawa Takuro、Ishikawa Yoichi、Funaki Yoshihito、Yoshikawa Takeo、Tashiro Manabu、Yanai Kazuhiko、Okamura Nobuyuki
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 7 Issue: 4
- DOI
  10.1002/prp2.499
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06886, KAKENHI-PROJECT-17K20083, KAKENHI-PROJECT-16H05385, KAKENHI-PROJECT-17K16753, KAKENHI-PROJECT-18K15538, KAKENHI-PROJECT-18H02771
[Journal Article] Longitudinal changes in 18F-THK5351 PET in corticobasal syndrome2019
- Author(s)
  Ezura M, Kikuchi A, Ishiki A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Kobayashi M, Tano O, Nakashima I, Mugikura S, Iwata R, Taki Y, Furukawa K, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M
- Journal Title
  
  Eur J Neurol
  
  Volume: 26 Issue: 9 Pages: 1205-1211
- DOI
  10.1111/ene.13966
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-17K20083, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-16H05385, KAKENHI-PROJECT-17K09318, KAKENHI-PROJECT-17K09744, KAKENHI-PROJECT-17K09745, KAKENHI-PROJECT-18K15538, KAKENHI-PROJECT-18H02771
[Journal Article] Neuroimaging-pathological correlations of [(18)F]THK5351 PET in progressive supranuclear palsy2018
- Author(s)
  Ishiki A, Furukawa K, et al.
- Journal Title
  
  Acta Neuropathol Commun
  
  Volume: 6 Issue: 1 Pages: 53-53
- DOI
  10.1186/s40478-018-0556-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09318, KAKENHI-PROJECT-17K20083, KAKENHI-PROJECT-16H05383, KAKENHI-PROJECT-16H05385, KAKENHI-PROJECT-18H02738, KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-16K15570, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15538, KAKENHI-PLANNED-26117003
[Journal Article] Newly-Developed Positron Emission Mammography (PEM) Device for the Detection of Small Breast Cancer2018
- Author(s)
  Yanai A, Itoh M, Hirakawa H, Yanai K, Tashiro M, Harada R, Yoshikawa A, Yamamoto S, Ohuchi N, Ishida T.
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 245 Issue: 1 Pages: 13-19
- DOI
  10.1620/tjem.245.13
- NAID
  130006731329
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K20083, KAKENHI-PROJECT-16H05385, KAKENHI-PROJECT-18K15538, KAKENHI-PLANNED-26117003
[Journal Article] Histamine elicits glutamate release from cultured astrocytes2018
- Author(s)
  Karpati Aniko、Yoshikawa Takeo、Nakamura Tadaho、Iida Tomomitsu、Matsuzawa Takuro、Kitano Haruna、Harada Ryuichi、Yanai Kazuhiko
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 137 Issue: 2 Pages: 122-128
- DOI
  10.1016/j.jphs.2018.05.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06886, KAKENHI-PROJECT-18J11446, KAKENHI-PROJECT-18K15538, KAKENHI-PLANNED-26117003
[Journal Article] Imaging Protein Misfolding in the Brain Using β-Sheet Ligands2018
- Author(s)
  Harada Ryuichi、Okamura Nobuyuki、Furumoto Shozo、Yanai Kazuhiko
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 12 Pages: 585-585
- DOI
  10.3389/fnins.2018.00585
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-16K15570, KAKENHI-PROJECT-18K15538, KAKENHI-PLANNED-26117003
[Journal Article] Involvement of the Precuneus/Posterior Cingulate Cortex Is Significant for the Development of Alzheimer’s Disease: A PET (THK5351, PiB) and Resting fMRI Study2018
- Author(s)
  Yokoi Takamasa、Watanabe Hirohisa、Ishigaki Shinsuke、Katsuno Masahisa、Miyao Shinichi、Kato Katsuhiko、Naganawa Shinji、Harada Ryuichi、Okamura Nobuyuki、Yanai Kazuhiko、Yoshida Mari、Sobue Gen （ほか9名）
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 10 Pages: 304-304
- DOI
  10.3389/fnagi.2018.00304
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07367, KAKENHI-PROJECT-18K19510, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-17H04259, KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-17K16117, KAKENHI-PROJECT-18K15538, KAKENHI-PLANNED-26117003
[Journal Article] Heparan sulfate in pancreatic β-cells contributes to normal glucose homeostasis by regulating insulin secretion.2018
- Author(s)
  Matsuzawa T, Yoshikawa T, Iida T, Karpati A, Kitano H, Harada R, Nakamura T, Sugawara A, Yamaguchi Y, Yanai K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: - Issue: 3 Pages: 688-695
- DOI
  10.1016/j.bbrc.2018.03.213
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253016, KAKENHI-PROJECT-16K18389, KAKENHI-PROJECT-18K06886, KAKENHI-PROJECT-16H03252, KAKENHI-PROJECT-18J11446, KAKENHI-PROJECT-18K15538, KAKENHI-PLANNED-26117003
[Journal Article] Site-Specific Labeling of F-18 Proteins Using a Supplemented Cell-Free Protein Synthesis System and O-2-[18F]Fluoroethyl-L-Tyrosine: [18F]FET-HER2 Affibody Molecule2018
- Author(s)
  Yanai Ai、Harada Ryuichi、Iwata Ren、Yoshikawa Takeo、Ishikawa Yoichi、Furumoto Shozo、Ishida Takanori、Yanai Kazuhiko
- Journal Title
  
  Molecular Imaging and Biology
  
  Volume: - Issue: 3 Pages: 529-537
- DOI
  10.1007/s11307-018-1266-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05383, KAKENHI-PROJECT-18K15538, KAKENHI-PLANNED-26117003
[Journal Article] Tau imaging with [18F]THK-5351 in progressive supranuclear palsy.2017
- Author(s)
  Ishiki A, Harada R, Okamura N, Tomita N, Rowe CC, Villemagne VL, Yanai K, Kudo Y, Arai H, Furumoto S, Tashiro M, Furukawa K.
- Journal Title
  
  Eur J Neurol.
  
  Volume: 24 Issue: 1 Pages: 130-136
- DOI
  10.1111/ene.13164
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-15K15268, KAKENHI-PROJECT-15K19767, KAKENHI-PROJECT-17K09318, KAKENHI-PROJECT-16H06621
[Journal Article] Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain.2017
- Author(s)
  Ng KP, Pascoal TA, Mathotaarachchi S, Therriault J, Kang MS, Shin M, Guiot MC, Guo Q, Harada R, Comley RA, Massarweh G, Soucy JP, Okamura N, Gauthier S, Rosa-Neto P.
- Journal Title
  
  Alzheimers Res Ther.
  
  Volume: 9:25 Issue: 1 Pages: 25-25
- DOI
  10.1186/s13195-017-0253-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-15K19767
[Journal Article] 18F-Labeled 2-Arylquinoline Derivatives for Tau Imaging: chemical, radiochemical, biological and clinical features2017
- Author(s)
  Shozo Furumoto, Tetsuro Tago, Ryuichi Harada, Yukitsuka Kudo, Nobuyuki Okamura
- Journal Title
  
  Current Alzheimer Research
  
  Volume: 14(2) Issue: 2 Pages: 178-185
- DOI
  10.2174/1567205013666160620121811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19767
[Journal Article] Structure-Activity Relationship of 2-Arylquinolines as PET Imaging Tracers for Tau Pathology in Alzheimer’s Disease2016
- Author(s)
  Tetsuro Tago, Shozo Furumoto, Nobuyuki Okamura, Ryuichi Harada, Hajime Adachi, Yoichi Ishikawa, Kazuhiko Yanai, Ren Iwata, and Yukitsuka Kudo
- Journal Title
  
  Journal of Nuclear Medicine
  
  Volume: 57(4) Issue: 4 Pages: 608-614
- DOI
  10.2967/jnumed.115.166652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19767, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-14J06908, KAKENHI-PROJECT-25293259, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-16H05383, KAKENHI-PROJECT-16K15570
[Journal Article] Advances in the development of tau PET radiotracers and their clinical applications.2016
- Author(s)
  Okamura N, Harada R, Furukawa K, Furumoto S, Tago T, Yanai K, Arai H, Kudo Y.
- Journal Title
  
  Ageing Res Rev.
  
  Volume: - Pages: 107-113
- DOI
  10.1016/j.arr.2015.12.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15268, KAKENHI-PROJECT-15K19767, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-14J06908, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-16K15570
[Journal Article] Synthesis and characterization of 18F-interleukin-8 using a cell-free translation system and 18F-fluoro-L-proline, Journal of Nuclear Medicine2016
- Author(s)
  Ryuichi Harada, Shozo Furumoto, Takeo Yoshikawa, Yoichi Ishikawa, Katsutoshi Shibuya, Nobuyuki Okamura, Kiichi Ishiwata, Ren Iwata, Kazuhiko Yanai
- Journal Title
  
  Journal of Nuclear Medicine
  
  Volume: 57(4) Issue: 4 Pages: 634-639
- DOI
  10.2967/jnumed.115.162602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19767, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-14J06908, KAKENHI-PROJECT-26253016, KAKENHI-PROJECT-15K15444, KAKENHI-PROJECT-16K18389
[Journal Article] Characteristics of Tau and Its Ligands in PET Imaging2016
- Author(s)
  Ryuichi Harada, Nobuyuki Okamura, Shozo Furumoto, Tetsuro Tago, Kazuhiko Yanai, Hiroyuki Arai, Yukitsuka Kudo
- Journal Title
  
  Biomolecules
  
  Volume: 6 Issue: 1 Pages: 1-15
- DOI
  10.3390/biom6010007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19767, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-14J06908
[Journal Article] microPET Imaging of Tau pathology with [18F]THK-5117 in two Transgenic Mouse Models2016
- Author(s)
  Matthias Brendel, Anna Jaworska, Federico Probst, Felix Overhoff, Viktoria Korzhova, Simon Lindnerm Janette Carlsen, Peter Bartenstein, Ryuichi Harada, Yukitsuka Kudo, Christian Haass, Fred van Leuven, Nobuyuki Okamura, Jochen Herms, and Axel Rominger
- Journal Title
  
  Journal of Nuclear Medicine
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19767
[Journal Article] In vivo visualization of tau pathology using 18F-THK5351 PET in corticobasal syndrome.2016
- Author(s)
  Kikuchi A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Kobayashi M, Tano O, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Ezura M, Hiraoka K, Mugikura S, Takase K, Iwata R, Taki Y, Furukawa K, HArai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A，Aoki M.
- Journal Title
  
  Neurology
  
  Volume: 87 Issue: 22 Pages: 2309-2316
- DOI
  10.1212/wnl.0000000000003375
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01550, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-15K19767, KAKENHI-PROJECT-26461303, KAKENHI-PROJECT-16K15570
[Journal Article] 18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease2016
- Author(s)
  Harada R, Okamura N, Furumoto S, Furukawa K, Ishiki A, Tomita N, Tago T, Hiraoka K, Watanuki S, Shidahara M, Miyake M, Ishikawa Y, Matsuda R, Inami A, Yoshikawa T, Funaki Y, Iwata R, Tashiro M, Yanai K, Arai H, Kudo Y
- Journal Title
  
  J Nucl Med
  
  Volume: 57 Issue: 2 Pages: 208-214
- DOI
  10.2967/jnumed.115.164848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08127, KAKENHI-PROJECT-15K15268, KAKENHI-PROJECT-15K19767, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-26253016, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-14J06908, KAKENHI-PROJECT-25670525, KAKENHI-PROJECT-26830041, KAKENHI-PROJECT-25293259, KAKENHI-PROJECT-16H05383
[Journal Article] Characterization of the radiolabeled metabolite of tau PET tracer 18F-THK5351.2016
- Author(s)
  Harada R, Furumoto S, Tago T, Furukawa K, Ishiki A, Tomita N, Iwata R, Tashiro M, Arai H, Yanai K, Kudo Y, Okamura N.
- Journal Title
  
  Eur J Nucl Med Mol Imaging.
  
  Volume: 43 Issue: 12 Pages: 2211-2218
- DOI
  10.1007/s00259-016-3453-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-15K19767, KAKENHI-PROJECT-16K15570
[Journal Article] Longitudinal Assessment of Tau Pathology in Patients with Alzheimer’s Disease Using [18F]THK-5117 Positron Emission Tomography2015
- Author(s)
  Aiko Ishiki, Nobuyuki Okamura, Katsutoshi Furukawa, Shozo Furumoto, Ryuichi Harada, Naoki Tomita, Kotaro Hiraoka, Shoichi Watanuki, Yoichi Ishikawa, Tetsuro Tago, Yoshihito Funaki, Ren Iwata, Manabu Tashiro, Kazuhiko Yanai, Yukitsuka Kudo, Hiroyuki Arai
- Journal Title
  
  PLos One
  
  Volume: 10(10) Pages: 1-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19767
[Journal Article] Preclinical evaluation of [18F]THK-5015 enantiomers: effects of chirality on its effectiveness as a tau imaging radiotracer.2015
- Author(s)
  Tago T., Furumoto S., Okamura N., Harada R., Adachi H., Ishikawa Y., Yanai K., Iwata R., Kudo Y.
- Journal Title
  
  Mol. Imaging Biol.
  
  Volume: 未定 Issue: 2 Pages: 258-266
- DOI
  10.1007/s11307-015-0879-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15444, KAKENHI-PROJECT-15K19767, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-14J06908, KAKENHI-PROJECT-25293257, KAKENHI-PROJECT-25293259, KAKENHI-PROJECT-15H04900
[Patent] タウを画像化する新規化合物2019
- Inventor(s)
  原田龍一他
- Industrial Property Rights Holder
  原田龍一他
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-240189
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19KK0212
[Patent] タウを画像化する新規化合物2019
- Inventor(s)
  原田龍一、他4名
- Industrial Property Rights Holder
  原田龍一、他4名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-240189
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K15538
[Patent] モノアミンオキシダーゼBイメージングプローブ2018
- Inventor(s)
  原田龍一、古本祥三、工藤幸司、岡村信行
- Industrial Property Rights Holder
  原田龍一、古本祥三、工藤幸司、岡村信行
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K15538
[Patent] ポジトロン放出核種標識タンパク質合成方法2017
- Inventor(s)
  原田龍一、谷内一彦、岩田錬、古本祥三、谷内亜衣
- Industrial Property Rights Holder
  原田龍一、谷内一彦、岩田錬、古本祥三、谷内亜衣
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-219798
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K15314
[Patent] MONOAMINE OXIDASE B BINDERS2016
- Inventor(s)
  古本祥三、工藤幸司、岡村信行、原田龍一
- Industrial Property Rights Holder
  古本祥三、工藤幸司、岡村信行、原田龍一
- Industrial Property Rights Type
  特許
- Filing Date
  2016-12-18
- Overseas
- Data Source
  KAKENHI-PROJECT-15K19767
[Patent] MONOAMINE OXIDASE B BINDERS2015
- Inventor(s)
  古本祥三、岡村信行、工藤幸司、原田龍一
- Industrial Property Rights Holder
  古本祥三、岡村信行、工藤幸司、原田龍一
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-18
- Overseas
- Data Source
  KAKENHI-PROJECT-15K19767
[Presentation] Analysis of [18F]SMBT-1 binding to reactive astrogliosis in postmortem brain tissues from patients with Alzheimer's disease and frontotemporal lobar degeneration.2023
- Author(s)
  Okamura N, Harada R, Du Y, Yokoyama Y, Kudo Y, Tashiro M, Furumoto S.
- Organizer
  SNMMI 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0123
[Presentation] 分子イメージングのトランスレーショナルリサーチ2023
- Author(s)
  原田龍一
- Organizer
  第31回日本医学会総会、東京、2023年4月
- Invited
- Data Source
  KAKENHI-PROJECT-23K24070
[Presentation] 神経炎症の画像化を目的としたPET薬剤の結合性の比較.2023
- Author(s)
  原田龍一, 工藤楓, 石川洋一, 岩田錬, 工藤幸司, 田代学, 古本祥三, 岡村信行.
- Organizer
  日本核医学会
- Data Source
  KAKENHI-PROJECT-23K21420
[Presentation] 新規アストロサイトイメージング薬剤[18F]SMBT-1の有用性2023
- Author(s)
  田代学, 平岡宏太良, 平岡宏太良, 冨田尚希, 小林良太, TEKEA Berihu, WU Yingying, 原田龍一, 菊地飛鳥, 菊地飛鳥, 武田和子, 草場美津江, 草場美津江, 菊池昭夫, 古川勝敏, 渡部浩司, 渡部浩司, 麦倉俊司, 川勝忍, 石井賢二, 二橋尚志, 加藤隆司, 古本祥三, 岡村信行.
- Organizer
  日本核医学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21420
[Presentation] Development of a highly sensitive tau tracer 18F-SNFT-1 for imaging early tau pathology in Alzheimer’s disease2023
- Author(s)
  Okamura N, Harada R, Lerdsirisuk P, Shimizu Y, Yokoyama Y, Du Y, Ezura M, Arai H, Kudo Y, Furumoto S
- Organizer
  AD/PD2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] 新規PETトレーサー［18F］SMBT-1による腫瘍評価可能性の探索2023
- Author(s)
  阿部未玲、外山由貴、前川由依、齋藤美穂子、高浪健太郎、原田龍一、古本祥三、田代学、高瀬圭.
- Organizer
  日本医学放射線学会北日本地方会・日本核医学会北日本地方会合同大会
- Data Source
  KAKENHI-PROJECT-23K21420
[Presentation] 新規PET薬剤[18F]SMBT-1を用いたAD疾患連続体の進行予後予測に関する早期観察結果.2023
- Author(s)
  田代学, 平岡宏太郎, 平岡宏太郎, 冨田尚希, 石木愛子, TEKEA Berihu, TEKEA Berihu, WU Yingying, 原田龍一, 菊地飛鳥, 菊地飛鳥, 武田和子, 草場美津江, 草場美津江, 菊池昭夫, 古川勝敏, 渡部浩司, 渡部浩司, 麦倉俊司, 小林良太, 川勝忍, 石井賢二, 加藤隆司, 古本祥三,岡村信行.
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-23K21420
[Presentation] 新規タウPETトレーサー[18F]SNFT-1の前臨床評価2023
- Author(s)
  岡村信行，原田龍一，ルーッスィリスックプラディット，清水悠暉，横山裕香，堵怡青，工藤幸司，古本祥三．
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-22KK0123
[Presentation] Development of a highly sensitive tau tracer 18F-SNFT-1 for imaging early tau pathology in Alzheimer’s disease2023
- Author(s)
  Okamura N, Harada R, Lerdsirisuk P, Shimizu Y, Yokoyama Y, Du Y, Ezura M, Arai H, Kudo Y, Furumoto S.
- Organizer
  AD/PD2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] 前頭側頭葉変性症における[18F]SMBT-1 PET所見.2023
- Author(s)
  小林良太, 川勝忍, 森岡大智, 平岡宏太良, 冨田尚希, 四月朔日聖一, MESFIN Berihu, WU Yingying, 武田和子, 草場美津江, 菊池昭夫, 渡部浩司, 麦倉俊司, 古川勝敏, 石井賢二, 加藤隆司, 原田龍一, 古本祥三, 岡村信行, 田代学.
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-23K21420
[Presentation] [18F]SMBT-1のHPLC分析条件の最適化.2023
- Author(s)
  池沼宏, 木村泰之, 戸次雄一, 阿部潤一郎, 原田龍一, 岡村信行, 古本祥三, 田代学, 加藤隆司.
- Organizer
  日本核医学会
- Data Source
  KAKENHI-PROJECT-23K21420
[Presentation] Development of a highly sensitive tau tracer 18F-SNFT-1 for imaging early tau pathology in Alzheimer’s disease.2023
- Author(s)
  Okamura N, Harada R, Lerdsirisuk P, Shimizu Y, Yokoyama Y, Du Y, Ezura M, Arai H, Kudo Y, Furumoto S.
- Organizer
  AD/PD2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0123
[Presentation] 第二世代タウPETトレーサーの結合性比較2022
- Author(s)
  横山裕香，原田龍一，Pradith Lerdsirisuk，清水悠暉，堵怡青，石川洋一，工藤幸司，岡村信行，荒井啓行，谷内一彦
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] Whole-body PET examination with [18F]SMBT-1 to observe physiological distribution of monoamine oxidase B (MAO-B) in humans2022
- Author(s)
  Tashiro M, Ishioka Y, Mesfin BT, Inamura A,Watanuki S, Miyake M, Hiraoka K, Harada R, Furumoto S, Yanai K, Okamura N, Watabe H.
- Organizer
  35th Annual Congress of European Association of Nuclear Medicine (EANM2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21420
[Presentation] [18F]SNFT-1の結合選択性評価および第二世代PETトレーサとのADタウに対する結合性比較2022
- Author(s)
  清水悠暉、原田龍一、横山裕香、Pradith Lerdsirisuk、石川洋一、岩田錬、工藤幸司、谷内一彦、岡村信行、古本祥三
- Organizer
  第21回放射性医薬品・画像診断薬研究会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] Physiological uptake of [18F]SMBT-1, a new astrogliosis tracer, in various organs of human body.2022
- Author(s)
  Tashiro M, Ishioka Y, Mesfin BT, Inamura A,Watanuki S, Miyake M, Hiraoka K, Harada R, Furumoto S, Yanai K, Okamura N, Watabe H.
- Organizer
  13th Congress of the World Federation of Nuclear Medicine and Biology (WFNMB2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21420
[Presentation] [18F]SNFT-1の結合選択性評価および第二世代タウPET トレーサーとのADタウに対する結合性比較2022
- Author(s)
  清水悠暉，原田龍一，横山裕香，Pradith Lerdsirisuk，石川洋一，岩田錬，工藤幸司，谷内一彦，岡村信行，古本祥三
- Organizer
  第5回日本核医学会分科会　放射性薬品科学研究会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] Physiological uptake of [18F]SMBT-1, a new astrogliosis tracer, in whole-body organs2022
- Author(s)
  Tashiro M, Ishioka Y, Mesfin B, Watanuki S, Hiraoka K, Harada R, Furumoto S, Okamura N, Yanai K, Watabe H
- Organizer
  13th Congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] PETプローブを用いた神経病理画像化に関する研究2022
- Author(s)
  原田龍一
- Organizer
  第95回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] 新規PETトレーサー[18F]SMBT-1の全身生理的集積の評価2022
- Author(s)
  メスフィン・ベリフ、石岡有生、稲村瑛仁、四月朔日聖一、三宅正泰、平岡宏太良、原田龍一、古本祥三、岡村信行、渡部浩司、田代学
- Organizer
  第42回日本医学放射線学会北日本地方会／日本核医学会北日本地方会[合同開催]
- Data Source
  KAKENHI-PROJECT-23K21420
[Presentation] アストログリオーシスを画像化するための PETプローブの開発とその応用2022
- Author(s)
  原田龍一
- Organizer
  第95回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] アストログリオーシスを画像化するための PETプローブの開発とその応用2022
- Author(s)
  原田龍一
- Organizer
  第95回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] 神経炎症モデルラットにおけるグリア線維性酸性タンパク質イメージング手法の開発2022
- Author(s)
  盛戸貴裕, 原田龍一, 岩田錬, 岡村信行, 谷内一彦
- Organizer
  第23回応用薬理学会シンポジウム
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] 認知症疾患の層別化における[18F]SMBT-1の有用性の検討プロジェクトの経過報告 20222022
- Author(s)
  田代学, 平岡宏太良, 平岡宏太良, 冨田尚希, 石木愛子, 小林良太, 四月朔日聖一, メスフィンベリフ, 武田和子, 草場美津江, 菊池昭夫, 渡部浩司, 麦倉俊司, 古川勝敏, 加藤隆司, 石井賢二, 川勝忍, 原田龍一, 古本祥三, 岡村信行．
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] 第二世代タウPETトレーサーの結合性比較2022
- Author(s)
  横山裕香，原田龍一，Pradith Lerdsirisuk，清水悠暉，堵怡青，石川洋一，工藤幸司，岡村信行，荒井啓行，谷内一彦
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] PETプローブを用いた神経病理画像化に関する研究2022
- Author(s)
  原田龍一
- Organizer
  第95回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] フェルラ酸誘導体のαシヌクレイン凝集・抑制効果の検討2022
- Author(s)
  原田龍一, 陳梦格, 工藤幸司, 谷内一彦, 岡村信行
- Organizer
  第23回応用薬理学会シンポジウム
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] ヒト剖検脳を用いたTDP-43型前頭側頭葉変性症における[18F]SMBT-1の有用性の検討2022
- Author(s)
  横山裕香、原田龍一、石川洋一、岩田錬、工藤幸司、岩崎靖、谷内一彦、岡村信行、古本祥三
- Organizer
  第21回放射性医薬品・画像診断薬研究会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] 認知症疾患の層別化における[18F]SMBT-1の有用性の検討プロジェクトの経過報告 20222022
- Author(s)
  田代学, 平岡宏太良, 平岡宏太良, 冨田尚希, 石木愛子, 石木愛子, 小林良太, 四月朔日聖一, 四月朔日聖一, メスフィンベリフ, 武田和子, 草場美津江, 菊池昭夫, 渡部浩司, 渡部浩司, 麦倉俊司, 古川勝敏, 古川勝敏, 加藤隆司, 石井賢二, 川勝忍, 原田龍一, 古本祥三, 古本祥三, 岡村信行
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] レビー小体型認知症(DLB)剖検脳を用いた神経炎症PETプローブの結合性評価2022
- Author(s)
  横山裕香, 原田龍一, 石川洋一, 岩田錬, 工藤幸司, 谷内一彦, 村山繁雄, 岡村信行, 古本祥三
- Organizer
  第23回応用薬理学会シンポジウム
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] ヒト剖検脳を用いたTDP-43型前頭側頭葉変性症における[18F]SMBT-1の有用性の検討2022
- Author(s)
  横山裕香, 原田龍一, 石川洋一, 岩田錬, 工藤幸司, 岩崎靖, 谷内一彦, 岡村信行, 古本祥三
- Organizer
  第5回日本核医学会分科会　放射性薬品科学研究会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] 神経炎症モデルラットにおけるグリア線維性酸性タンパク質イメージング手法の開発2022
- Author(s)
  盛戸貴裕、原田龍一、岩田錬、岡村信行、谷内一彦
- Organizer
  第23回応用薬理学会シンポジウム
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] Physiological uptake of [18F]SMBT-1, a new astrogliosis tracer, in whole-body organs2022
- Author(s)
  Tashiro M, Ishioka Y, Mesfin B, Watanuki S, Hiraoka K, Harada R, Furumoto S, Okamura N, Yanai K, Watabe H
- Organizer
  13th Congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] レビー小体型認知症(DLB)剖検脳を用いた神経炎症PETプローブの結合性評価2022
- Author(s)
  横山裕香、原田龍一、石川洋一、岩田錬、工藤幸司、谷内一彦、村山繁雄、岡村信行、古本祥三
- Organizer
  第23回応用薬理学会シンポジウム
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] 神経炎症イメージングのための新規PET薬剤[18F]SMBT-1の動態解析（Work in Progress）2022
- Author(s)
  平岡宏太良、メスフィン・ベリフ、石岡有生、四月朔日聖一、石川洋一、船木善仁、稲村瑛仁、原田龍一、石木愛子、古本祥三、岡村信行、渡部浩司、田代学
- Organizer
  第42回日本医学放射線学会北日本地方会／日本核医学会北日本地方会[合同開催]
- Data Source
  KAKENHI-PROJECT-23K21420
[Presentation] 18F標識タンパク質を用いた脳内PETイメージング手法の開発に向けて2021
- Author(s)
  盛戸貴裕, 原田龍一, 岩田錬, 古本祥三, 岡村信行, 工藤幸司, 谷内一彦
- Organizer
  放射性医薬品研究会2021
- Data Source
  KAKENHI-PROJECT-20K21564
[Presentation] 前頭側頭型変性症で認めるアストロサイト様構造物に対するアミロイド・タウPETプローブの結合性評価2021
- Author(s)
  横山裕香，原田龍一，荒井啓行，工藤幸司，古本祥三，岡村信行，谷内一彦
- Organizer
  第72回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] アミロイド・タウPETプローブのアストロサイト様構造物に対する結合性評価2021
- Author(s)
  横山裕香, 原田龍一, 荒井啓行, 工藤幸司, 古本祥三, 岡村信行, 谷内一彦
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] オフターゲット結合を示さない高感度タウPETプローブの開発2021
- Author(s)
  原田龍一，Pradith Lerdsirisuk，清水悠暉，堵怡青，石川洋一, 荒井啓行, 工藤幸司，谷内一彦，岩田錬, 古本祥三，岡村信行
- Organizer
  放射性薬品科学研究会2021
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] 嗜銀顆粒性認知症に対するPETバイオマーカーの探索2021
- Author(s)
  原田龍一，堵恰青， Pradith Lerdsirisuk, 工藤幸司，古本祥三，岡村信行，谷内一彦
- Organizer
  第72回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] Off-target結合のない新規タウPETプローブの開発2021
- Author(s)
  清水悠暉, 原田龍一, Pradith Lerdsirisuk, 堵怡青, 工藤幸司, 石川洋一, 岩田錬, 岡村信行, 谷内一彦, 古本祥三
- Organizer
  第61回日本核医学会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] アストロサイト画像化を目的とした PETプローブ[18F]SMBT-1の代謝特性の検討2021
- Author(s)
  原田龍一、堵怡青、工藤幸司、岡村信行、古本祥三、谷内一彦
- Organizer
  日本分子イメージング学会・第15回総会・学術総会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] MAO-Bを標的としたアストロサイトの画像化2021
- Author(s)
  原田　龍一
- Organizer
  第37回BFIC
- Invited
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] Off-target結合のない新規タウPETプローブの開発2021
- Author(s)
  清水悠暉, 原田龍一, Pradith Lerdsirisuk, 堵怡青, 工藤幸司, 石川洋一, 岩田錬, 岡村信行, 谷内一彦, 古本祥三
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] Amyloid, tau and reactive astrocytosis imaging in aging and Alzheimer’s disease2021
- Author(s)
  Victor L Villemagne Ryuichi Harada, Vincent Dore, Shozo Furumoto, Rachel Mulligan, Yukitsuka Kudo, Samantha Burnham, Natasha Krishnadas, Kun Huang, Kazuhiko Yanai, Christopher C Rowe, and Nobuyuki Okamura
- Organizer
  ADPD2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] ヒト剖検脳に対するMAO-B PETプローブ[18F]SMBT-1の結合2021
- Author(s)
  原田龍一、堵怡青、横山裕香、古本祥三、工藤幸司、荒井啓行、畠野雄也、石原智彦、小野寺理、吉田眞理、北本哲之、岩崎靖、谷内一彦、岡村信行
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] 第二世代タウPETトレーサーの結合性の比較2021
- Author(s)
  原田龍一，Pradith Lerdsirisuk ，清水悠暉，堵怡青，石川洋一, 荒井啓行, 工藤幸司，岩田錬, 谷内一彦，古本祥三，岡村信行
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] 健常者を対象としたPET診断薬18F-SMBT-1の全身臓器における生理的集積の観察2021
- Author(s)
  石岡有生、四月朔日聖一、平岡宏太良、石川洋一、船木善仁、原田龍一、岡村信行、荒井啓行、古本祥三、谷内一彦、渡部浩司、田代学
- Organizer
  第42回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] アストロサイト画像化を目的とした PETプローブ[18F]SMBT-1の代謝特性の検討2021
- Author(s)
  原田龍一、堵怡青、工藤幸司、岡村信行、古本祥三、谷内一彦
- Organizer
  日本分子イメージング学会・第15回総会・学術総会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] 第二世代タウPETトレーサーの結合性の比較2021
- Author(s)
  原田龍一，Pradith Lerdsirisuk，清水悠暉，堵怡青，石川洋一, 荒井啓行, 工藤幸司，岩田錬, 谷内一彦，古本祥三，岡村信行
- Organizer
  第61回日本核医学会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] アミロイド・タウPETプローブのアストロサイト様構造物に対する結合性評価2021
- Author(s)
  横山裕香, 原田龍一, 荒井啓行, 工藤幸司, 古本祥三, 岡村信行&, 谷内一彦
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] 生体脳の分子イメージングに向けた18F標識タンパク質の検討2021
- Author(s)
  盛戸貴裕、原田龍一、岩田練、岡村信行、谷内一彦
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21564
[Presentation] 反応性アストロサイトを標的としたPET プローブ [18F]SMBT-12021
- Author(s)
  原田龍一, 工藤幸司, 荒井啓行, 田代学, 古本祥三, 岡村信行, 谷内一彦
- Organizer
  第42回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] Conformation-dependent fluorescence probe THK-5320 for tissue staining: Implication of amyloid heterogeneity in human brains2021
- Author(s)
  Gonzalo Carmona Soto, Ryuichi Harada, Shozo Furumoto, Nobuyuki Okamura, Yukitsuka Kudo, Kazuhiko Yanai
- Organizer
  日本分子イメージング学会・第15回総会・学術総会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] オフターゲット結合を示さない高感度タウPETプローブの開発2021
- Author(s)
  原田龍一，Pradith Lerdsirisuk，清水悠暉，堵怡青，石川洋一, 荒井啓行, 工藤幸司，谷内一彦，岩田錬, 古本祥三，岡村信行
- Organizer
  放射性薬品科学研究会2021
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] 神経変性プロセスを可視化する PETプローブの開発2021
- Author(s)
  原田　龍一
- Organizer
  第4回医薬品開発研究センターシンポジウム　脳と創薬
- Invited
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] 18F標識タンパク質による脳内分子イメージング手法の開発2021
- Author(s)
  盛戸貴裕、原田龍一、岩田練、堵怡青、岡村信行、工藤幸司、谷内一彦
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K21564
[Presentation] Advances in MAO-B Imaging2021
- Author(s)
  Ryuichi Harada
- Organizer
  34th Annual Congress of the European Association of Nuclear Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] 反応性アストロサイトを標的としたPET プローブ [18F]SMBT-12021
- Author(s)
  原田龍一, 工藤幸司, 荒井啓行, 田代学, 古本祥三, 岡村信行, 谷内一彦
- Organizer
  第42回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] Advances in MAO-B Imaging2021
- Author(s)
  Ryuichi Harada
- Organizer
  34th Annual Congress of the European Association of Nuclear Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] Off-target結合のない新規タウPETプローブの開発2021
- Author(s)
  清水悠暉、原田龍一、Pradith Lerdsirisuk、堵怡青、工藤幸司、石川洋一、岩田錬、岡村信行、谷内一彦、古本祥三
- Organizer
  日本分子イメージング学会・第15回総会・学術総会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] ヒト剖検脳に対するMAO-B PETプローブ[18F]SMBT-1の結合2021
- Author(s)
  原田龍一、堵怡青、横山裕香、古本祥三、工藤幸司、荒井啓行、畠野雄也4 、石原智彦4 、小野寺理、吉田眞理、北本哲之、岩崎靖、谷内一彦、岡村信行
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] Binding characterization of a PET tracer [18F]SMBT-1 for imaging reactive astrocytes using postmortem human brain tissues2021
- Author(s)
  堵怡青、原田龍一、Pradith Lerdsirisuk、赤井田優、石川洋一、工藤幸司、荒井啓行、吉田眞理、古本祥三、岡村信行、谷内一彦
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] 嗜銀顆粒性認知症に対するPETバイオマーカーの探索2021
- Author(s)
  原田龍一，堵恰青， Pradith Lerdsirisuk, 工藤幸司，古本祥三，岡村信行，谷内一彦
- Organizer
  第72回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] PHFタウへの感度・特異度に優れた新規タウプローブ[18F]SNFT-1の開発2021
- Author(s)
  岡村信行、原田龍一、清水悠暉、Pradith Lerdsirisuk、堵怡青、石川洋一、荒井啓行、谷内一彦、工藤幸司、古本祥三
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] 前頭側頭型変性症で認めるアストロサイト様構造物に対するアミロイド・タウPETプローブの結合性評価2021
- Author(s)
  横山裕香，原田龍一，荒井啓行，工藤幸司，古本祥三，岡村信行，谷内一彦
- Organizer
  第72回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] MAO-B、活性化アストロサイトのイメージング2020
- Author(s)
  原田龍一
- Organizer
  第60回日本核医学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] 反応性アストロサイトの画像化を目的としたPETプローブ [18F]SMBT-1 と [3H]BU-99008 の結合性の比較2020
- Author(s)
  堵怡青、原田龍一、盛戸貴裕、荒井啓行、工藤幸司、古本祥三、岡村信行、谷内一彦
- Organizer
  第71回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-20K08043
[Presentation] Preclicanil characterization of [18F]THK-5562, a novel tau PET tracer with little off-target binding2020
- Author(s)
  Ryuichi Harada, Pradith Lerdisirisuk, Yiqing Du, Michinori Ezura, Yuki Shimizu, Takahiro Morito, Hiroyuki Arai, Kazuhiko Yanai, Yukitsuka Kudo, Shozo Furumoto, Nobuyuki Okamura
- Organizer
  Human Amyloid Imging 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15538
[Presentation] Assessing Abe-a, tau, and reactive astrocytosis in aging and AD2020
- Author(s)
  Victor L Villemagne, Ryuichi Harada, Kazuhiko Yanai, et al.
- Organizer
  HUMAN AMYLOID IMAGING CONFERENCE 2020（マイアミ）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] Preclinical characterization of [18F]THK-5562, a novel tau PET tracer with little off-target binding2020
- Author(s)
  Harada R, Lerdsirisuk P, Du Y, Ezura M, Shimizu Y, Morito T, Arai H, Yanai K,Kudo Y, Furumoto S, Okamura N
- Organizer
  HUMAN AMYLOID IMAGING CONFERENCE 2020（マイアミ）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] Evaluation of the novel 18F-labeled PET tracer SMBT-1 for imaging astrogliosis in healthy elderly controls and in Alzheimer’s disease2020
- Author(s)
  Victor L Villemagne Ryuichi Harada, Vincent Dore, Shozo Furumoto, Rachel Mulligan, Yukitsuka Kudo, Samantha Burnham, Natasha Krishnadas, Kun Huang, Kazuhiko Yanai, Christopher C Rowe, and Nobuyuki Okamura
- Organizer
  AAIC2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] 非天然アミノ酸の導入技術によるタンパク質RI標識法の開発2020
- Author(s)
  盛戸貴裕、原田龍一、岩田練、谷内一彦
- Organizer
  第71回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-20K21564
[Presentation] Development and Identification of [18F]SNFT-1 (THK-5562), a Promising Candidate for Selective Tau PET Tracer in Alzheimer’s Disease2020
- Author(s)
  Pradith Lerdsirisuk, Ryuichi Haradac, Yuki Shimizub, Yiqing Du, Yoichi Ishikawa, Ren Iwata, Kazuhiko Yanai, Yukitsuka Kudo, Nobuyuki Okamurab, Shozo Furumoto
- Organizer
  EANM2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] Monoamine oxidase-B for Imaging of Reactive Astrocytes2020
- Author(s)
  原田龍一
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] Assessing Abeta, tau, and reactive astrocytosis in aging and AD2020
- Author(s)
  Victor Villemagne, Ryuichi Harada, Dore, Shozo Furumoto, Rachel Mulligan, Yukitsuka Kudo, Natasha KrisKun Huang, Kazuhiko Yanai, Christopher C Rowe, Nobuyuki Okamura
- Organizer
  Human Amyloid Imging 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15538
[Presentation] Discovery and evaluation of a novel tau PET tracer [F-18]THK-5562 for Alzheimer's disease2020
- Author(s)
  Du Y, Harada R, Lerdsirisuk P, Ezura M, Shimizu Y, Morito T, Arai H, Kudo Y, Furumoto S, Yanai K
- Organizer
  第93回日本薬理学会（横浜）
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] 脳内PETイメージングに向けたBBB透過性ペプチド融合affibodyの薬物動態2019
- Author(s)
  盛戸貴裕、原田龍一、堵怡青、岩田錬、古本祥三、谷内一彦
- Organizer
  第70回日本薬理学会北部会（札幌）
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] Radiolabeled proteins for the development of biopharmaceuticals2019
- Author(s)
  原田龍一
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K15538
[Presentation] アストロサイトのPETイメージング2019
- Author(s)
  原田龍一
- Organizer
  PETサマーセミナー 2019
- Invited
- Data Source
  KAKENHI-PROJECT-18K15538
[Presentation] Discovery of [18F]SMBT-1: a novel selective MAO-B PET trcer for imaging astrogliosis2019
- Author(s)
  Ryuichi Harada
- Organizer
  Human Amyloid Imaging 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15538
[Presentation] アストロサイトのPETトレーサー2019
- Author(s)
  原田龍一
- Organizer
  第38回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15538
[Presentation] アストロサイトのPETトレーサー2019
- Author(s)
  原田龍一
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0212
[Presentation] Development of selective tau and MAO-B PET through compound optimization of [18F]THK-53512018
- Author(s)
  Ryuichi Harada
- Organizer
  World Congress of Pharmacology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15538
[Presentation] アンバーコドンを用いた無細胞蛋白質合成法による新規18F標識蛋白質合成法の開発2018
- Author(s)
  原田龍一
- Organizer
  第58回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15538
[Presentation] フェルラ酸誘導体によるミスフォールディング蛋白質の凝集抑制2018
- Author(s)
  原田龍一
- Organizer
  第69回日本薬理学会北部会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15538
[Presentation] Pathological correlates of 18F-THK-5351 PET in tauopathies2018
- Author(s)
  Ryuichi Harada
- Organizer
  Congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15538
[Presentation] Characterizing the “off-target” binding of 18F-THK5351 in Alzheimer’s disease: correlation between ante-mortem and post-mortem findings.2017
- Author(s)
  Ryuichi Harada, Aiko Ishiki, Shozo Furumoto, Katsutoshi Furukawa, Manabu Tashiro, Arai Hiroyuki, Kazuhiko Yanai, Yukitsuka Kudo, Nobuyuki Okamura
- Organizer
  11th Human Amyloid Imaging
- Place of Presentation
  Miami, USA
- Year and Date
  2017-01-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19767
[Presentation] Development of a lanthanide complex labeled β-sheet ligand for high-throughput screening using time-resolved fluorescence method2017
- Author(s)
  原田龍一、岡村信行、古本祥三、吉川雄朗、工藤幸司、谷内一彦
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎新聞文化ホール（長崎県・長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K19767
[Presentation] Identification of wavelength-dependent compounds for imaging Lewy pathology2016
- Author(s)
  Ryuichi Harada, Nobuyuki Okamura, Shozo Furumoto, Ren Iwata, Hiroyuki Arai, Kazuhiko Yanai, Yukitsuka Kudo
- Organizer
  AAIC2016
- Place of Presentation
  Toronto, Canada
- Year and Date
  2016-07-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19767
[Presentation] 東北大学におけるタウPETプローブの基礎開発研究2016
- Author(s)
  原田龍一
- Organizer
  第6回日本認知症予防学会
- Place of Presentation
  東北大学（宮城県・仙台市）
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-15K19767
[Presentation] Metabolite analysis of tau PET tracer [18F]THK-53512016
- Author(s)
  Ryuichi Harada, Nobuyuki Okamura, Shozo Furumoto, Tetsuro Tago, Katsutoshi Furukawa, Aiko Ishiki, Ren Iwata, Manabu Tashiro, Hiroyuki Arai, Kazuhiko Yanai, Yukitsuka Kudo
- Organizer
  Human Amyloid Imaging Conference 2016
- Place of Presentation
  Miami, USA
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19767
[Presentation] タウPETプローブ[18F]THK-5351の結合特性の解析2015
- Author(s)
  原田龍一、岡村信行、古本祥三、古川勝敏、石木愛子、岩田錬、谷内一彦、荒井啓行、工藤幸司
- Organizer
  第34回日本認知症学会
- Place of Presentation
  リンクステーション青森（青森県・青森市）
- Year and Date
  2015-10-04
- Data Source
  KAKENHI-PROJECT-15K19767
[Presentation] タウイメージングトレーサーの[18F]THK-5351の代謝解析2015
- Author(s)
  原田龍一、岡村信行、古本祥三、多胡哲郎、岩田錬、谷内一彦、工藤幸司
- Organizer
  第55回日本核医学会学術総会
- Place of Presentation
  ハイアットリージェンシー東京（東京都・新宿区）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-15K19767
[Presentation] Validation of the binding specificity of tau PET tracer [18F]THK-5351 on postmortem human brain samples2015
- Author(s)
  Ryuichi Harada, Nobuyuki Okamura, Shozo Furumoto, Aiko Ishiki, Katsutoshi Furukawa, Tomita Naoki, Tetsuro Tago, Ren Iwata, Kazuhiko Yanai, Hiroyuki Arai, Yukitsuka Kudo
- Organizer
  AAIC2015
- Place of Presentation
  Washington D.C., USA
- Year and Date
  2015-07-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19767
[Presentation] Characterization of [18F]THK-5351 for imaging of tau pathology in Alzheimer's disease2015
- Author(s)
  Ryuichi Harada, Nobuyuki Okamura, Shozo Furumoto, Testuro Tago, Ren Iwata, Kazuhiko Yanai, Hiroyuki Arai, Yukitsuka Kudo
- Organizer
  第10回日本分子イメージング学会
- Place of Presentation
  タワーホール船堀（東京都･江戸川区）
- Year and Date
  2015-05-18
- Data Source
  KAKENHI-PROJECT-15K19767

1. Yanai Kazuhiko (50192787)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
2. 古本祥三 (00375198)

# of Collaborated Projects: 4 results

# of Collaborated Products: 40 results
3. 岡村信行 (40361076)

# of Collaborated Projects: 3 results

# of Collaborated Products: 35 results
4. KATO KOICHI (50382198)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 吉川雄朗 (70506633)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 熊本卓哉 (50292678)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 原田愛子 (30778634)

# of Collaborated Projects: 2 results

# of Collaborated Products: 40 results
8. 高瀬圭 (60361094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. Iwata Ren (60143038)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 高橋和弘 (20370257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田代学 (00333477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
12. 藤本敏彦 (00229048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 外山由貴 (30770862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 渡部浩司 (40280820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
15. 平岡宏太良 (70586049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
16. 菊池昭夫 (80463785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. 高浪健太郎 (90447160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 佐々木要 (10611783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 皆川栄子 (20726252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 金田朋洋 (50323019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 中村正帆 (80734318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 石川洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 古川勝敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 石井賢二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 青木正志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 石垣診祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HARADA Ryuichi 原田 龍一

Ryuichi Harada 原田 龍一

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Research for imaging of ApoE proteinopathyPrincipal Investigator

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Reverse translational research for imaging astrogliosisPrincipal Investigator

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Development of PET probes for visualization of neurodegenerative processPrincipal Investigator

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Comparative study of tau imaging tracersPrincipal Investigator

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[Journal Article] 4.Preclinical Characterization of the Tau PET Tracer [18F]SNFT-1: Comparison of Tau PET Tracers.2023

HARADA Ryuichi 原田龍一

Ryuichi Harada 原田龍一