CHIKATA TAKAYUKI 近田貴敬

Researcher Number	60749711
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2023: 熊本大学, ヒトレトロウイルス学共同研究センター, 特任講師 2019: 熊本大学, ヒトレトロウイルス学共同研究センター, 特任助教 2018: 熊本大学, エイズ学研究センター, 特任助教 2016 – 2017: 熊本大学, エイズ学研究センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related / Infectious disease medicine Except Principal Investigator Basic Section 54030:Infectious disease medicine-related
Keywords	Principal Investigator HIV-1 / HIV-1特異的T細胞 / エピトープ / ワクチン / HESN / HIV予防ワクチン / 潜伏感染細胞 / CTL反応 / HIV感染症根治 / 抗レトロウイルス療法 … More / HIV-1特異的CTL / HIV-1潜伏感染細胞 / リザーバー / ART / CD8 / Shock and Kill / CTL / ウイルス / 免疫学 / 感染症 / オーバーラップドペプチド / Gag領域 / HIV-1特異的CD4T細胞 / Gag / HIV-1特異的CD4陽性T細胞 … More Except Principal Investigator HIV-1 / コレセプター / エピゲノム解析 / coreceptor / CXCR4 / CCR5 / 逃避変異 / 完治療法 / 細胞傷害性T細胞 Less

Epigenetic analysis of viral and host factors for the regulation of X4 HIV-1
- Principal Investigator
  
  前田洋助
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kumamoto University
HIVハイリスク非感染者における感染防御に寄与する細胞傷害性T細胞の同定Principal Investigator
- Principal Investigator
  
  近田貴敬
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kumamoto University
Identification and induction of cytotoxic T cells for HIV-1 cure treatment
- Principal Investigator
  
  Takiguchi Masafumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kumamoto University
Identification of HIV-1-specific CTLs from HIV-1-infected individuals on long-term antiretroviral therapy (ART)Principal Investigator
- Principal Investigator
  
  CHIKATA TAKAYUKI
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kumamoto University
Study on HIV-1-specific CD4+ T cells that can control HIV-1 replication.Principal Investigator
- Principal Investigator
  
  CHIKATA TAKAYUKI
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kumamoto University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] HIV-1 protective epitope-specific CD8+ T?cells in HIV-1-exposed seronegative individuals2023
- Author(s)
  Chikata Takayuki、Gatanaga Hiroyuki、Nguyen Hung The、Mizushima Daisuke、Zhang Yu、Kuse Nozomi、Oka Shinichi、Takiguchi Masafumi
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 11 Pages: 108089-108089
- DOI
  10.1016/j.isci.2023.108089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08603
[Journal Article] Immunological Control of HIV-1 Disease Progression by Rare Protective HLA Allele2022
- Author(s)
  Zhang Yu、Chikata Takayuki、Kuse Nozomi、Murakoshi Hayato、Gatanaga Hiroyuki、Oka Shinichi、Takiguchi Masafumi
- Journal Title
  
  Journal of Virology
  
  Volume: 96 Issue: 22
- DOI
  10.1128/jvi.01248-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03726, KAKENHI-PROJECT-20K07549
[Journal Article] Control of HIV-1 Replication by CD8+ T Cells Specific for Two Novel Pol Protective Epitopes in HIV-1 Subtype A/E Infection.2022
- Author(s)
  Nguyen HT, Kuse N, Zhang Y, Murakoshi H, Maeda Y, Tamura Y, Maruyama R, Tran GV, Nguyen TV, Nguyen KV, Oka S, Chikata T, Takiguchi M.
- Journal Title
  
  Journal of Virology
  
  Volume: 96 Issue: 19
- DOI
  10.1128/jvi.00811-22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08602, KAKENHI-PROJECT-19K08932, KAKENHI-PROJECT-20K07549
[Journal Article] Collaboration of a Detrimental HLA-B*35:01 Allele with HLA-A*24:02 in Coevolution of HIV-1 with T Cells Leading to Poorer Clinical Outcomes2021
- Author(s)
  Kuse Nozomi、Murakoshi Hayato、Akahoshi Tomohiro、Chikata Takayuki、James Katherine L.、Gatanaga Hiroyuki、Rowland-Jones Sarah L.、Oka Shinichi、Takiguchi Masafumi
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 23
- DOI
  10.1128/jvi.01259-21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03726
[Journal Article] Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-12020
- Author(s)
  Zhang Yu、Kuse Nozomi、Akahoshi Tomohiro、Chikata Takayuki、Gatanaga Hiroyuki、Oka Shinichi、Murakoshi Hayato、Takiguchi Masafumi
- Journal Title
  
  Journal of Virology
  
  Volume: 94 Issue: 19
- DOI
  10.1128/jvi.01151-20
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07549, KAKENHI-PROJECT-20H03726
[Journal Article] Broad Recognition of Circulating HIV-1 by HIV-1-Specific Cytotoxic T-Lymphocytes with Strong Ability to Suppress HIV-1 Replication2019
- Author(s)
  Murakoshi H*, Kuse N*, Akahoshi T, Zhang Y, Chikata T, Borghan MA, Gatanaga H, Oka S, Sakai K, Takiguchi M (* equal contribution)
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 1
- DOI
  10.1128/jvi.01480-18
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-18K16181, KAKENHI-PROJECT-15H02658
[Journal Article] Effective suppression of HIV-1 replication by CTLs specific for Pol epitopes in conserved mosaic vaccine immunogens2019
- Author(s)
  Zou C*, Murakoshi H*, Kuse N, Akahoshi T, Chikata T, Gatanaga H, Oka S, Hanke T, Takiguchi M (*Equal contribution)
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 7
- DOI
  10.1128/jvi.02142-18
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-18K16181, KAKENHI-PROJECT-15H02658
[Journal Article] Identification of immunodominant HIV-1 epitopes presented by HLA-C*12:02, a protective allele, using an immunopeptidomics approach2019
- Author(s)
  Chikata T, Paes W, Akahoshi T, Partridge T, Murakoshi H, Gatanaga H, Ternette N, Oka S, Borrow P, Takiguchi M
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 17
- DOI
  10.1128/jvi.00634-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-18K16181
[Journal Article] CD8+ T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication2018
- Author(s)
  Murakoshi H*, Zou C*, Kuse N, Akahoshi T, Chikata T, Gatanaga H, Oka S, Hanke T, Takiguchi M (* equal contribution)
- Journal Title
  
  Retrovirology
  
  Volume: 15 Issue: 1 Pages: 46-46
- DOI
  10.1186/s12977-018-0429-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-18K16181, KAKENHI-PROJECT-15H02658
[Journal Article] Control of HIV-1 by an HLA-B*52:01-C*12:02 Protective Haplotype2017
- Author(s)
  Chikata Takayuki、Murakoshi Hayato、Koyanagi Madoka、Honda Kazutaka、Gatanaga Hiroyuki、Oka Shinichi、Takiguchi Masafumi
- Journal Title
  
  The Journal of Infectious Diseases
  
  Volume: 216 Issue: 11 Pages: 1415-1424
- DOI
  10.1093/infdis/jix483
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08129, KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-16K19614
[Journal Article] Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.2017
- Author(s)
  Murakoshi H, Koyanagi M, Chikata T, Rahman MA, Kuse N, Sakai K, Gatanaga H, Oka S, Takiguchi M.
- Journal Title
  
  J Virol.
  
  Volume: 91(4) Issue: 4
- DOI
  10.1128/jvi.02082-16
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240, KAKENHI-PROJECT-15K19588, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19614
[Journal Article] HLA Class I-Mediated HIV-1 Control in Vietnamese Infected with HIV-1 Subtype A/E2017
- Author(s)
  Chikata Takayuki、Tran Giang Van、Murakoshi Hayato、Akahoshi Tomohiro、Qi Ying、Naranbhai Vivek、Kuse Nozomi、Tamura Yoshiko、Koyanagi Madoka、Sakai Sachiko、et al.
- Journal Title
  
  Journal of Virology
  
  Volume: 92 Issue: 5
- DOI
  10.1128/jvi.01749-17
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08129, KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-15H02658, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19160, KAKENHI-PROJECT-16K19614
[Journal Article] Potential for immune-driven viral polymorphisms to compromise antiretroviral-based preexposure prophylaxis for prevention of HIV-1 infection2017
- Author(s)
  Gatanaga H, Brumme ZL, Adland E, Reyes-Teran G, Avila-Rios S, Mejia-Villatoro CR, Hayashida T, Chikata T, Van Tran G, Van Nguyen K, Meza RI, Palou EY, Valenzuela-Ponce H, Pascale JM, Porras-Cortes G, Manzanero M, Lee GQ, Martin JN, Carrington MN, John M, Mallal S, Poon AFY, Goulder P, Takiguchi M, Oka S
- Journal Title
  
  AIDS
  
  Volume: 31 Issue: 14 Pages: 1935-1943
- DOI
  10.1097/qad.0000000000001575
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02658, KAKENHI-PROJECT-16K19614
[Presentation] Immunological Control of HIV-1 Disease Progression by Rare Protective HLA Allele2023
- Author(s)
  Zhang Yu、Chikata Takayuki、Kuse Nozomi、Murakoshi Hayato、Gatanaga Hiroyuki、Oka Shinichi、Takiguchi Masafumi
- Organizer
  Oxford-Kumamoto Universities Joint Annual Symposium 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03726
[Presentation] サブタイプA/E HIV-1感染麻薬常用者におけるR5ウイルスとX4ウイルスの混合感染の解析2023
- Author(s)
  前田洋助, 近田貴敬, 竹村太一郎, 寺沢広美, Giang Van Trang, 久世望, Trung Vu Nguyen, Kinh Van Nguyen, 澤智裕, 長谷部太, 滝口雅文
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08602
[Presentation] HIVハイリスク非感染者におけるHIV-1特異的細胞傷害性T細胞の同定2022
- Author(s)
  近田貴敬
- Organizer
  第36回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K08603
[Presentation] Control of HIV-1 by an HLA-B*52:01-HLA-C*12:02 protective haplotype2017
- Author(s)
  Takayuki Chikata, Hayato Murakoshi, Madoka Koyanagi, Masafumi Takiguchi
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19614
[Presentation] Identification of a detrimental HLA haplotype and the effect of its associated HIV-1 mutations in HIV-1 subtype A/E-infected Vietnamese2017
- Author(s)
  Takayuki Chikata, Hayato Murakoshi, Tomohiro Akahoshi, Nozomi Kuse, Yoshiko Tamura, Keiko Sakai, Masafumi Takiguchi
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19614
[Presentation] 日本人およびベトナム人HIV-1感染者の病態進行の抑制に関与する細胞傷害性T細胞2017
- Author(s)
  近田貴敬
- Organizer
  第31回日本エイズ学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K19614
[Presentation] Control of HIV-1 by HLA-B*52:01-restricted or C*12:02-restricted cytotoxic T lymphocytes specific for 6 epitopes in an HIV-1-infected Japanese cohort where HLA-B*57 and HLA-B*27 are very rare2017
- Author(s)
  Takayuki Chikata, Hayato Murakoshi, Madoka Koyanagi, Kazutaka Honda, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi
- Organizer
  IAS 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19614
[Presentation] HLA class I-mediated HIV-1 control in Vietnamese infected with HIV-1 subtype A/E2017
- Author(s)
  Chikata T, Tran GV, Murakoshi H, Akahoshi T, Qi Y, Naranbhai V, Kuse N, Tamura Y, Koyanagi M, Sakai S, Nguyen DH, Nguyen DT, Nguyen HT, Nguyen TV, Oka S, Martin MP, Carrington M, Sakai K, Nguyen KV, Takiguchi M
- Organizer
  18th Kumamoto AIDS Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19614
[Presentation] ベトナム人HIV-1サブタイプA/E感染者コホートにおける、エイズ病態進行に関与するHLAアリルおよびHLA関連HIV-1多型のエイズ病態進行に及ぼす影響2017
- Author(s)
  近田貴敬, Tran Van Giang, 村越勇人, 田村美子, 赤星智寛, 久世望, 阪井恵子, 小柳円, Kinh Van Nguyen, 滝口雅文
- Organizer
  第31回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-16K19614

1. Takiguchi Masafumi (00183450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 前田洋助 (30284764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 刈谷龍昇 (40757663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. GATANAGA Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. KUSE Nozomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. MURAKOSHI Hayato

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
7. 小柳円

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 岡慎一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

CHIKATA TAKAYUKI 近田 貴敬

Research Projects

Research Products

Co-Researchers

Epigenetic analysis of viral and host factors for the regulation of X4 HIV-1

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HIVハイリスク非感染者における感染防御に寄与する細胞傷害性T細胞の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and induction of cytotoxic T cells for HIV-1 cure treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of HIV-1-specific CTLs from HIV-1-infected individuals on long-term antiretroviral therapy (ART)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on HIV-1-specific CD4+ T cells that can control HIV-1 replication.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] HIV-1 protective epitope-specific CD8+ T?cells in HIV-1-exposed seronegative individuals2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunological Control of HIV-1 Disease Progression by Rare Protective HLA Allele2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Control of HIV-1 Replication by CD8+ T Cells Specific for Two Novel Pol Protective Epitopes in HIV-1 Subtype A/E Infection.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Collaboration of a Detrimental HLA-B*35:01 Allele with HLA-A*24:02 in Coevolution of HIV-1 with T Cells Leading to Poorer Clinical Outcomes2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-12020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Broad Recognition of Circulating HIV-1 by HIV-1-Specific Cytotoxic T-Lymphocytes with Strong Ability to Suppress HIV-1 Replication2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effective suppression of HIV-1 replication by CTLs specific for Pol epitopes in conserved mosaic vaccine immunogens2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of immunodominant HIV-1 epitopes presented by HLA-C*12:02, a protective allele, using an immunopeptidomics approach2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD8+ T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Control of HIV-1 by an HLA-B*52:01-C*12:02 Protective Haplotype2017

CHIKATA TAKAYUKI 近田貴敬

[Journal Article] Collaboration of a Detrimental HLA-B35:01 Allele with HLA-A24:02 in Coevolution of HIV-1 with T Cells Leading to Poorer Clinical Outcomes2021

[Journal Article] Control of HIV-1 by an HLA-B52:01-C12:02 Protective Haplotype2017

[Journal Article] Accumulation of Pol Mutations Selected by HLA-B52:01-C12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.2017

[Presentation] Control of HIV-1 by an HLA-B52:01-HLA-C12:02 protective haplotype2017

[Presentation] Control of HIV-1 by HLA-B52:01-restricted or C12:02-restricted cytotoxic T lymphocytes specific for 6 epitopes in an HIV-1-infected Japanese cohort where HLA-B57 and HLA-B27 are very rare2017