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Muguruma Kyohei  六車 共平

ORCIDConnect your ORCID iD *help
Researcher Number 60753621
Other IDs
Affiliation (Current) 2025: 東京科学大学, 総合研究院, 助教
Affiliation (based on the past Project Information) *help 2025: 東京科学大学, 総合研究院, 助教
2024: 東京工業大学, 科学技術創成研究院, 助教
2022: 国立研究開発法人理化学研究所, 開拓研究本部, 基礎科学特別研究員
2020 – 2021: 東京工業大学, 物質理工学院, JSPS特別研究員
Review Section/Research Field
Principal Investigator
Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Except Principal Investigator
Basic Section 90120:Biomaterials-related
Keywords
Principal Investigator
抗体 / ペプチド / FcRn / プロドラッグ / 遷移金属触媒 / 触媒活性制御 / 金属触媒 / アルブミン / 触媒 / ルテニウム … More
Except Principal Investigator
… More がん / 造影剤 / ナノテクノロジー / 高分子 Less
  • Research Projects

    (3 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (2 People)
  •  フォールディング効果に基づく緩和性能の向上とグリーン造影剤の創製

    • Principal Investigator
      三浦 裕
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Institute of Science Tokyo
  •  Biodistribution control of IgG by selective inhibition of FcRn interactionPrincipal Investigator

    • Principal Investigator
      六車 共平
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      Tokyo Institute of Technology
  •  Development of catalytic activity regulation system using affinity peptidesPrincipal Investigator

    • Principal Investigator
      Muguruma Kyohei
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      Institute of Physical and Chemical Research
      Tokyo Institute of Technology

All 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Therapeutic in vivo synthetic chemistry using an artificial metalloenzyme with glycosylated human serum albumin2022

    • Author(s)
      Kenshiro Yamada, Kyohei Muguruma, Katsunori Tanaka
    • Journal Title

      Adv. Carbohydr. Chem. Biochem.

      Volume: 82 Pages: 11-34

    • DOI

      10.1016/bs.accb.2022.10.001

    • ISBN
      9780323985970
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K15968
  • [Journal Article] In vivo metal-catalyzed SeCT therapy by a proapoptotic peptide.2021

    • Author(s)
      hmad, P.; Muguruma, K.; Chang, T.-C.; Tamura, S.; Tsubokura, K.; Egawa, Y.; Suzuki, T.; Dohmae, N.; Nakao, Y.; *Tanaka, K.
    • Journal Title

      Chem. Sci.

      Volume: 12 Issue: 37 Pages: 12266-12273

    • DOI

      10.1039/d1sc01784e

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K05718, KAKENHI-PROJECT-19K15708, KAKENHI-PROJECT-21H02065, KAKENHI-PROJECT-19J00396, KAKENHI-PROJECT-21K19042, KAKENHI-PROJECT-20K15968
  • [Presentation] 生体内利用を目指したルテニウム触媒-アルブミン複合体の開発2023

    • Author(s)
      六車共平
    • Organizer
      蛋白研セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K15968
  • [Presentation] 親和性ペプチドを利用したルテニウム触媒の触媒活性制御2023

    • Author(s)
      六車共平、田中克典
    • Organizer
      日本薬学会 第143年会
    • Data Source
      KAKENHI-PROJECT-20K15968
  • [Presentation] 日本化学会 第102 春季年会2022

    • Author(s)
      六車共平、田中克典
    • Organizer
      生体内利用を指向したシクロペンタジエニルルテニウム触媒の機能化
    • Data Source
      KAKENHI-PROJECT-20K15968
  • [Presentation] ルテニウム触媒の生体内利用とがん治療への応用2022

    • Author(s)
      六車共平、Peni Ahmadi、張宗哲、田中克典
    • Organizer
      日本薬学会 第142年会
    • Data Source
      KAKENHI-PROJECT-20K15968
  • [Presentation] がん治療に利用可能なルテニウム触媒複合体の開発2022

    • Author(s)
      六車共平,今井恭祐,Ambara R. Pradipta,田中克典
    • Organizer
      第39回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-20K15968
  • [Presentation] ルテニウム触媒複合体と天然ペプチド誘導体を用いた生体内タギング反応によるがん治療2022

    • Author(s)
      六車共平、Peni Ahmadi、今井恭祐、Tsung-Che Chang、Ambara R. Pradipta、田中克典
    • Organizer
      第64回 天然有機化合物討論会
    • Data Source
      KAKENHI-PROJECT-20K15968
  • [Presentation] Peptide/protein-mediated delivery of a ruthenium catalyst for in vivo tumor therapy2022

    • Author(s)
      Kyohei Muguruma, Kyosuke Imai, Ambara R. Pradipta, Katsunori Tanaka,
    • Organizer
      59th Japanese Peptide Symposium,
    • Data Source
      KAKENHI-PROJECT-20K15968
  • [Presentation] Metal-catalyzed selective cell tagging of a cytotoxic peptide for in vivo cancer therapy,2021

    • Author(s)
      Kyohei Muguruma, Peni Ahmadi, Tsung-Che Chang, and Katsunori Tanaka
    • Organizer
      58th Japanese Peptide Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K15968
  • [Presentation] マウス体内でのルテニウム触媒反応によるがん治療2021

    • Author(s)
      六車共平、Peni Ahmadi、張宗哲、田中克典
    • Organizer
      日本化学会 第101 春季年会
    • Data Source
      KAKENHI-PROJECT-20K15968
  • [Presentation] ルテニウム触媒による反応活性種の生成とマウス体内でのがん治療への利用2021

    • Author(s)
      六車共平、Peni Ahmadi、張宗哲、田中克典
    • Organizer
      第79回 有機合成化学協会 関東支部シンポジウム
    • Data Source
      KAKENHI-PROJECT-20K15968
  • [Presentation] Transition metal-catalyzed selective cell tagging (SeCT) therapy for cancer treatment2021

    • Author(s)
      Kyohei Muguruma, Peni Ahmadi, Tsung-Che Chang, and Katsunori Tanaka
    • Organizer
      13th AFMC (Asian Federation for Medicinal Chemistry) International medicinal chemistry symposium,
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K15968
  • 1.  三浦 裕 (40557980)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  田村 理
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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