Seki Soju 関壮樹

Researcher Number	60755081
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院歯学研究科, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪大学, 大学院歯学研究科, 助教 2022: 大阪大学, 歯学部附属病院, 助教 2019 – 2021: 大阪大学, 歯学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / 0907:Oral science and related fields Except Principal Investigator Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 筋萎縮性側索硬化症 / 咀嚼障害 / ALS / 三叉神経中脳路核 / バイオマーカー / 人工知能 / パッチクランプ / 電気生理 / 一次感覚神経 / AI … More / 遺伝子治療 / 電気生理学 / ナトリウム電流 / NPY / SOD1G93A / 三叉神経 / ディープラーニング / ALSモデルマウス … More Except Principal Investigator 人工知能 / 口腔粘膜疾患 / 口腔がん / ハイパースペクトルイメージング / 深層学習 Less

Development of a Novel ALS Therapeutic Strategy Targeting Primary Sensory NeuronsPrincipal Investigator
- Principal Investigator
  
  関壮樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka University
ハイパースペクトルイメージングの口腔粘膜解析dataを用いた新規口腔癌診断AIの開発
- Principal Investigator
  
  平岡慎一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka University
Treatment of masticatory disorders and development of ALS diagnostic biomarkers by fusion of AI and neurophysiological dataPrincipal Investigator
- Principal Investigator
  
  Seki Soju
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka University
口腔外科におけるBig Dataを用いた深層学習解析モデルの臨床応用に関する研究
- Principal Investigator
  
  平岡慎一郎
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka University
Electrophysiological and behavioral studies of ALS masticatory disorders using Artificial IntelligencePrincipal Investigator
- Principal Investigator
  
  Seki Soju
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0907:Oral science and related fields
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019

All Journal Article Presentation Book

[Book] 月刊「細胞」2023
- Author(s)
  関壮樹
- Total Pages
  2
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21K17088
[Journal Article] Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma2023
- Author(s)
  Usta Sena Zeynep、Uchihashi Toshihiro、Kodama Shingo、Kurioka Kyoko、Inubushi Toshihiro、Shimooka Takuya、Sugauchi Akinari、Seki Soju、Tanaka Susumu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 24 Pages: 17282-17282
- DOI
  10.3390/ijms242417282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17087, KAKENHI-PROJECT-21K17088
[Journal Article] Analysis of Feeding Behavior Characteristics in the Cu/Zn Superoxide Dismutase 1 (SOD1) SOD1G93A Mice Model for Amyotrophic Lateral Sclerosis (ALS)2023
- Author(s)
  Kitaoka Yoshihiro、Seki Soju、Kawata Sou、Nishiura Akira、Kawamura Kohei、Hiraoka Shin-ichiro、Kogo Mikihiko、Tanaka Susumu
- Journal Title
  
  Nutrients
  
  Volume: 15 Issue: 7 Pages: 1651-1651
- DOI
  10.3390/nu15071651
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10115, KAKENHI-PROJECT-20H03887, KAKENHI-PROJECT-21K17088
[Journal Article] Characteristics of Sensory Neuron Dysfunction in Amyotrophic Lateral Sclerosis (ALS): Potential for ALS Therapy2023
- Author(s)
  Seki Soju、Kitaoka Yoshihiro、Kawata Sou、Nishiura Akira、Uchihashi Toshihiro、Hiraoka Shin-ichiro、Yokota Yusuke、Isomura Emiko Tanaka、Kogo Mikihiko、Tanaka Susumu
- Journal Title
  
  Biomedicines
  
  Volume: 11 Issue: 11 Pages: 2967-2967
- DOI
  10.3390/biomedicines11112967
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17088
[Journal Article] Dentigerous cyst excision using shading films in a patient with erythropoietic protoporphyria2022
- Author(s)
  Soju Seki, Akira Nozoe, Takuya Shimooka, Kazuaki Miyagawa, Takayuki Hara, Kazuma Harada, Emiko Tanaka Isomura, Susumu Tanaka
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
  
  Volume: - Issue: 4 Pages: 417-422
- DOI
  10.1016/j.ajoms.2021.12.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K24117, KAKENHI-PROJECT-21K17088
[Journal Article] A case of localized nodular amyloidosis in the sublingual gland and submucosa of the mouth floor2021
- Author(s)
  原崇之, 石濱孝二, 外川健司, 関壮樹, 田中徳昭, 古郷幹彦
- Journal Title
  
  Japanese Journal of Oral and Maxillofacial Surgery
  
  Volume: 67 Issue: 11 Pages: 620-625
- DOI
  10.5794/jjoms.67.620
- NAID
  130008143211
- ISSN
  0021-5163, 2186-1579
- Year and Date
  2021-11-20
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K24117, KAKENHI-PROJECT-21K17088
[Journal Article] Membrane excitabilities in neonatal rat mesencephalic trigeminal neurons under dietary zinc deficiency2021
- Author(s)
  Saori Yamada , Susumu Tanaka , Soju Seki , Mikihiko Kogo
- Journal Title
  
  Journal of Oral Science
  
  Volume: 63 Issue: 3 Pages: 242-246
- DOI
  10.2334/josnusd.20-0566
- NAID
  130008058469
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K24117, KAKENHI-PROJECT-21K17088
[Journal Article] Persistent sodium conductance contributes to orexin-A-mediated modulation of membrane excitability in neonatal rat mesencephalic V neurons2021
- Author(s)
  Susumu Tanaka, Soju Seki, Yudai Ono, Akifumi Enomoto, Mikihiko Kogo
- Journal Title
  
  Neuroscience Letters
  
  Volume: 753 Pages: 753-753
- DOI
  10.1016/j.neulet.2021.135846
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K24117
[Journal Article] A case of sclerosing odontogenic carcinoma2021
- Author(s)
  Soju Seki, Susumu Tanaka, Takayuki Hara, Nao Nishimura, Kaori Oya, Toshihiro Uchihashi, Shinichiro Hiraoka, Munehiro Hamaguchi, Mikihiko Kogo
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
  
  Volume: 33 Issue: 6 Pages: 592-598
- DOI
  10.1016/j.ajoms.2021.03.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K24117, KAKENHI-PROJECT-21K10137, KAKENHI-PROJECT-21K17088
[Journal Article] Orexins modulate membrane excitability in rat trigeminal motoneurons2020
- Author(s)
  Tanaka Susumu、Higuchi Masataka、Seki Soju、Enomoto Akifumi、Kogo Mikihiko
- Journal Title
  
  Journal of Oral Science
  
  Volume: 62 Issue: 3 Pages: 265-270
- DOI
  10.2334/josnusd.19-0141
- NAID
  130007863790
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24117
[Journal Article] Neuropeptide Y modulates membrane excitability in neonatal rat mesencephalic V neurons2020
- Author(s)
  Seki Soju、Tanaka Susumu、Yamada Saori、Tsuji Tadataka、Enomoto Akifumi、Ono Yudai、Chandler Scott H.、Kogo Mikihiko
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 98 Issue: 5 Pages: 921-935
- DOI
  10.1002/jnr.24583
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24117, KAKENHI-PROJECT-16H05541
[Journal Article] Multiple canalicular adenomas arising in the buccal mucosa and upper lip: Case report and literature review2020
- Author(s)
  Kazuma Harada, Susumu Tanaka, Kaori Oya, Toshihiro Uchihashi, Yusuke Yokota, Soju Seki, Yohei Fujishita, Mikihiko Kogo
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
  
  Volume: 32 Issue: 6 Pages: 525-528
- DOI
  10.1016/j.ajoms.2020.07.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K24117
[Journal Article] Circuit-Specific Early Impairment of Proprioceptive Sensory Neurons in the SOD1G93A Mouse Model for ALS2019
- Author(s)
  Seki Soju、Yamamoto Toru、Quinn Kiara、Spigelman Igor、Pantazis Antonios、Olcese Riccardo、Wiedau-Pazos Martina、Chandler Scott H.、Venugopal Sharmila
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 39 Issue: 44 Pages: 8798-8815
- DOI
  10.1523/jneurosci.1214-19.2019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] Analysis of feeding behavior characteristics of ALS model mice2023
- Author(s)
  Yoshihiro Kitaoka, Soju Seki, Sou Kawata, Akira Nishiura, Kohei Kawamura, Shin-ichiro Hiraoka, Susumu Tanaka
- Organizer
  Oral Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] ALSモデルマウスにおける咀嚼機能と四肢運動機能の比較および筋体積減少の特徴2023
- Author(s)
  川田創, 関壮樹, 北岡好大, 西浦輝, 古郷幹彦, 田中晋
- Organizer
  日本口腔外科学会
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] ALSモデルマウスにおける摂食行動特性の解析2023
- Author(s)
  北岡好大, 関壮樹, 川田創, 西浦輝, 川村晃平, 平岡慎一郎, 田中晋
- Organizer
  日本口腔科学会
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] Analysis of feeding behavior characteristics of ALS model mice2023
- Author(s)
  北岡好大, 関壮樹, 川田創, 西浦輝, 川村晃平, 平岡慎一郎, 田中晋
- Organizer
  口腔顔面神経機能学会
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] Analysis of feeding behavior characteristics of ALS mice model2023
- Author(s)
  Yoshihiro Kitaoka, Soju Seki, Sou Kawata, Akira Nishiura, Kohei Kawamura, Shin-ichiro Hiraoka, Susumu Tanaka, Mikihiko Kogo
- Organizer
  .International Conference on Oral and Maxillofacial Surgery (ICOMS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] ラット鼓索神経における一般体性感覚受容とTRPチャネルとの関連ー舌動脈への選択的動注投与法による解明ー2023
- Author(s)
  岸上波輝, 横田祐介, 山内かれん, 高畑惣介, 山田早織, 関壮樹, 磯村恵美子, 石橋美樹, 田中晋
- Organizer
  口腔顔面神経機能学会
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] Analysis of feeding behavior characteristics of ALS model mice2023
- Author(s)
  北岡好大, 関壮樹, 川田創, 西浦輝, 川村晃平, 平岡慎一郎, 田中晋
- Organizer
  第26回口腔顔面神経機能学会
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] Analysis of feeding behavior characteristics of ALS model mice2023
- Author(s)
  Yoshihiro Kitaoka, Soju Seki, Sou Kawata, Akira Nishiura, Kohei Kawamura, Shin-ichiro Hiraoka, Mikihiko Kogo, Susumu Tanaka
- Organizer
  Oral Science 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] AIを用いたALSモデルマウスの咀嚼運動解析と体重減少との関係2022
- Author(s)
  北岡好大, 関壮樹, 川田創, 西浦輝, 平岡慎一郎, 田中晋
- Organizer
  第67回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] 摂食関連神経ペプチドによる三叉神経中脳路核ニューロン周波数応答特性の神経修飾作用2022
- Author(s)
  関壮樹, 田中晋, 山田早織, 石井庄一郎, 古郷幹彦
- Organizer
  第25回口腔顔面神経機能学会総会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] Early impairment of Mes V neuron comparing other types of sensory neurons in ALS model mouse2022
- Author(s)
  Soju Seki
- Organizer
  Oral Science 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] Early impairment of Mes V neuron comparing other types of sensory neurons in ALS model mouse2022
- Author(s)
  Soju Seki
- Organizer
  Oral Science 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] 摂食関連神経ペプチドによる三叉神経中脳路核ニューロン周波数応答特性の神経修飾作用2022
- Author(s)
  関壮樹, 田中晋, 山田早織, 石井庄一郎, 古郷幹彦
- Organizer
  第25回口腔顔面神経機能学会総会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] 骨格性Ⅱ級顎矯正手術後の後戻りと下顎頭体積変化の関係2021
- Author(s)
  関壮樹, 宮川和晃, 藤原采香, 宮本浩樹, 島岡祐加子, 有川千尋, 原田計眞, 相川友直
- Organizer
  第66回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K17088
[Presentation] 摂食関連神経ペプチドによる三叉神経中脳路核ニューロン周波数応答特性の神経修飾作用2021
- Author(s)
  関壮樹, 田中晋, 山田早織, 石井庄一郎, 古郷幹彦
- Organizer
  口腔顔面神経機能学会2021
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] 骨格性Ⅱ級顎矯正手術後の後戻りと下顎頭体積変化の関係2021
- Author(s)
  関壮樹, 宮川和晃, 藤原采香, 宮本浩樹, 島岡祐加子, 有川千尋, 原田計眞, 相川友直
- Organizer
  第66回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] 顎関節形成術におけるマイテックアンカースクリューの応用2020
- Author(s)
  相川友直, 新宅優子, 原田計眞, 関壮樹, 山田早織, 藤下陽平, 石原康貴, 古郷幹彦
- Organizer
  日本顎変形症学会雑誌2020
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] 硬化性歯原性癌の1例2020
- Author(s)
  関壮樹, 西村, 奈穂, 平岡, 慎一郎, 田中晋, 福田, 康夫, 笹平, 智則, 竹田, 雅司, 古郷, 幹彦, 濱口裕弘
- Organizer
  日本口腔外科学会2020
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] 骨格性II級顎矯正手術の術後安定性の検討2020
- Author(s)
  関壮樹, 新宅優子, 相川友直, 原田計眞, 山田早織, 古郷幹彦
- Organizer
  日本顎変形症学会雑誌2020
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] 遮光板を用いて含歯性嚢胞の摘出を行った骨髄性プロトポルフィリン症の1例2020
- Author(s)
  野添彬, 関壮樹, 下岡拓也, 小田紗矢香, 原崇之, 北川太二, 田中晋, 磯村恵美子, 古郷幹彦
- Organizer
  日本口腔外科学会2020
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] 下顎正中骨延長術の治療バリエーション2020
- Author(s)
  原田計眞, 相川友直, 新宅優子, 村田有香, 中津川昂平, 黒坂寛, 山本沙優里, 関壮樹, 山田早織, 山城隆, 古郷幹彦
- Organizer
  日本顎変形症学会雑誌2020
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] 摂食促進ペプチドNeuropeptide Yによる三叉神経中脳路核ニューロンのバースト活動促進に関わる発生機序の検討2020
- Author(s)
  関壮樹田中晋山田早織古郷幹彦
- Organizer
  第74回　口腔科学会学術大会
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] モデルマウスを用いたALS咀嚼障害の解明2020
- Author(s)
  北岡好大, 関壮樹, 平岡慎一郎, 田中晋, 古郷幹彦
- Organizer
  日本口腔外科学会2020
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] 摂食促進ペプチドNeuropeptide Yによる三叉神経中脳路核ニューロンのバースト活動促進に関わる発生機序の検討2020
- Author(s)
  関壮樹
- Organizer
  日本口腔科学会2020
- Data Source
  KAKENHI-PROJECT-19K24117
[Presentation] ALS 咀嚼障害における一次感覚ニューロンの解明と治療戦略2019
- Author(s)
  関壮樹田中晋山田早織 Scott Chandler Sharmila Venugopal 古郷幹彦
- Organizer
  第64回　口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K24117

1. 平岡慎一郎 (70615616)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. 李天鎬 (70792737)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 田中晋 (00367541)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 島田泰如 (50751757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山本徹 (20707335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 長野清一 (40362727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 内橋俊大 (60757839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 内山進 (90335381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 川村晃平 (20880157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 熊本康昭 (30611727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 藤田克昌 (80362664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 栗岡恭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Seki Soju 関 壮樹

Research Projects

Research Products

Co-Researchers

Development of a Novel ALS Therapeutic Strategy Targeting Primary Sensory NeuronsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ハイパースペクトルイメージングの口腔粘膜解析dataを用いた新規口腔癌診断AIの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Treatment of masticatory disorders and development of ALS diagnostic biomarkers by fusion of AI and neurophysiological dataPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

口腔外科におけるBig Dataを用いた深層学習解析モデルの臨床応用に関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Electrophysiological and behavioral studies of ALS masticatory disorders using Artificial IntelligencePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 月刊「細胞」2023

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of Feeding Behavior Characteristics in the Cu/Zn Superoxide Dismutase 1 (SOD1) SOD1G93A Mice Model for Amyotrophic Lateral Sclerosis (ALS)2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characteristics of Sensory Neuron Dysfunction in Amyotrophic Lateral Sclerosis (ALS): Potential for ALS Therapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dentigerous cyst excision using shading films in a patient with erythropoietic protoporphyria2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case of localized nodular amyloidosis in the sublingual gland and submucosa of the mouth floor2021

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[Journal Article] Membrane excitabilities in neonatal rat mesencephalic trigeminal neurons under dietary zinc deficiency2021

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[Journal Article] Persistent sodium conductance contributes to orexin-A-mediated modulation of membrane excitability in neonatal rat mesencephalic V neurons2021

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