Gotoh Saki 齊藤紗希 (後藤紗希)

… Alternative Names

GOTOH-SAITO Saki 齊藤紗希

後藤紗希

後藤紗希ゴトウサキ

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Researcher Number	60756609
Other IDs
Affiliation (Current)	2025: 公益財団法人東京都医学総合研究所, ゲノム医学研究センター, 研究員
Affiliation (based on the past Project Information) *help	2020 – 2023: 公益財団法人東京都医学総合研究所, ゲノム医学研究センター, 研究員 2017 – 2019: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員 2016: 金沢大学, 薬学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 48040:Medical biochemistry-related / Pharmacology in pharmacy
Keywords	Principal Investigator 遺伝子発現制御 / enhancer RNA / UGT1A1 / CAGE / エンハンサーRNA / PXR / 薬剤応答性エンハンサー / HIF2a / 癌 / リン酸化 … More / 癌の悪性化 / 上皮間葉転換 / HIF2α / Int6 / 糖尿病 / 脂肪酸のb酸化 / 転写 / ヒト肝細胞 / 脂肪酸のβ酸化 / 脂質代謝 / シグナル伝達 / 脂肪酸のβ 酸化 / 核内受容体 Less

網羅的 eRNA 発現解析による薬剤応答性エンハンサーの同定と機能解析Principal Investigator
- Principal Investigator
  
  齊藤紗希 (後藤紗希)
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Investigation of molecular mechanism for cancer progression through phosphorylation of Int6/eIF3ePrincipal Investigator
- Principal Investigator
  
  SAITO Saki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
翻訳開始因子 Int6/eIF3e の翻訳後修飾を介した癌悪性化機構の解明Principal Investigator
- Principal Investigator
  
  齊藤紗希 (後藤紗希)
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Investigation of the role of PXR-SGK2 signaling in drug-induced diabetesPrincipal Investigator
- Principal Investigator
  
  GOTOH-SAITO Saki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
  Kanazawa University

All 2023 2022 2021 2019 2017 2016

All Journal Article Presentation

[Journal Article] INT6/eIF3e represses E-cadherin expression through HIF2α in lung carcinoma A549 cells2022
- Author(s)
  Gotoh‐Saito Saki、Sadato Daichi、Shibasaki Futoshi
- Journal Title
  
  Genes to Cells
  
  Volume: 27 Issue: 12 Pages: 689-705
- DOI
  10.1111/gtc.12984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16373
[Journal Article] Characterization of human UGT2A3 expression using a prepared specific antibody against UGT2A32019
- Author(s)
  Gotoh-Saito Saki、Abe Takayuki、Furukawa Yoichi、Oda Shingo、Yokoi Tsuyoshi、Finel Moshe、Hatakeyama Masahiko、Fukami Tatsuki、Nakajima Miki
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 34 Issue: 4 Pages: 280-286
- DOI
  10.1016/j.dmpk.2019.05.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21055
[Journal Article] Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal2017
- Author(s)
  Gotoh Saki、Miyauchi Yuu、Moore Rick、Negishi Masahiko
- Journal Title
  
  Cellular Signalling
  
  Volume: 40 Pages: 200-209
- DOI
  10.1016/j.cellsig.2017.09.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K21055
[Presentation] ヒト肝癌細胞における薬剤誘導性エンハンサーRNAの機能解析2023
- Author(s)
  齊藤紗希, 和田涼子, 川路英哉
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K06396
[Presentation] Genome-wide profiling of enhancer RNA initiation events identified novel drug-responsive enhancers in human hepatocytes2023
- Author(s)
  Saki Gotoh-Saito, Ryoko Wada, Toyoaki Natsume, Hideya Kawaji
- Organizer
  第23回シトクロムP450国際会議
- Data Source
  KAKENHI-PROJECT-23K06396
[Presentation] Identification of the mechanism by which Int6/HIF2α-regulated E-cadherin expression in A549 lung cancer cells2021
- Author(s)
  齊藤紗希
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16373
[Presentation] 肝糖新生における核内受容体 PXR のグルコースセンサーとしての新機能解明2017
- Author(s)
  後藤紗希、Rick Moore、Masahiko Negishi
- Organizer
  Conference for BioSignal and Medicine (CBSM) 2017
- Data Source
  KAKENHI-PROJECT-16K21055
[Presentation] 核内受容体 PXR によるグルコースシグナル伝達の肝糖新生制御の解明2016
- Author(s)
  後藤紗希, 宮内優, Rick Moore, 根岸正彦
- Organizer
  H28内外環境応答・代謝酵素研究会
- Place of Presentation
  静岡県立大学薬学部 (静岡県・静岡市)
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-16K21055
[Presentation] スタチン誘導性脂質代謝おけるPXR-SGK2シグナル経路の役割2016
- Author(s)
  後藤紗希, 沓掛貴矢, 中島美紀
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (神奈川県・横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K21055

1. 川路英哉 (20525406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Gotoh Saki 齊藤 紗希 (後藤 紗希)

GOTOH-SAITO Saki 齊藤 紗希

後藤紗希

後藤 紗希 ゴトウ サキ

Research Projects

Research Products

Co-Researchers

網羅的 eRNA 発現解析による薬剤応答性エンハンサーの同定と機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of molecular mechanism for cancer progression through phosphorylation of Int6/eIF3ePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

翻訳開始因子 Int6/eIF3e の翻訳後修飾を介した癌悪性化機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the role of PXR-SGK2 signaling in drug-induced diabetesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] INT6/eIF3e represses E-cadherin expression through HIF2α in lung carcinoma A549 cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of human UGT2A3 expression using a prepared specific antibody against UGT2A32019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] ヒト肝癌細胞における薬剤誘導性エンハンサーRNAの機能解析2023

Author(s)

Organizer

Data Source

[Presentation] Genome-wide profiling of enhancer RNA initiation events identified novel drug-responsive enhancers in human hepatocytes2023

Author(s)

Organizer

Data Source

[Presentation] Identification of the mechanism by which Int6/HIF2α-regulated E-cadherin expression in A549 lung cancer cells2021

Author(s)

Organizer

Data Source

[Presentation] 肝糖新生における核内受容体 PXR のグルコースセンサーとしての新機能解明2017

Author(s)

Organizer

Data Source

[Presentation] 核内受容体 PXR によるグルコースシグナル伝達の肝糖新生制御の解明2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] スタチン誘導性脂質代謝おけるPXR-SGK2シグナル経路の役割2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Gotoh Saki 齊藤紗希 (後藤紗希)

GOTOH-SAITO Saki 齊藤紗希

後藤紗希ゴトウサキ