TIAN Yushi 田雨時

… Alternative Names

田雨時ティエンユイシー

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Researcher Number	60761252
Other IDs	https://orcid.org/0000-0002-8988-9453
Affiliation (Current)	2025: 大阪大学, 大学院薬学研究科, 助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪大学, 大学院薬学研究科, 助教 2018 – 2021: 大阪大学, 薬学研究科, 助教
Review Section/Research Field	Except Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Mathematical Sciences in Search of New Cooperation
Keywords	Except Principal Investigator 化学記述子 / Drug Design / Supervised Learning / United Learning / Computational Chemistry / Machine Learning / 正準相関分析 / PIEDA / 部分最小二乗法 / PLS … More / 重回帰分析 / IFIE / FMO / Chk1阻害剤 / シフト検定法 / グレブナー基底 / 医薬品有害事象 / Random Forest / JADER / 重大副作用 / 多数決法 / ランダムフォレスト / サポートベクターマシン / 副作用予測 / 多変量解析 / ROC曲線 / AI / 重篤希少有害事象 / マルチラベル学習 / スティーブンス・ジョンソン症候群 / 悪性症候群 / Stacking / ATCコード / 機械学習 / 有害事象 Less

Drug Design using Computational Chemistry and Multiple Supervised Machine Learning Systems based on Correlation between the Systems
- Principal Investigator
  
  高木達也
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Osaka University
Modeling for Prediction of Serious Adverse Events Probabilities of Drug Candidates
- Principal Investigator
  
  TAKAGI Tatsuya
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Mathematical Sciences in Search of New Cooperation
- Research Institution
  Osaka University

All 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Computational <i>ab initio</i> interaction analyses between neutralizing antibody and SARS-CoV-2 variant spike proteins using the fragment molecular orbital method2021
- Author(s)
  Watanabe Kazuki、Watanabe Chiduru、Honma Teruki、Tian Yu-Shi、Kawashima Yusuke、Kawashita Norihito、Fukuzawa Kaori、Takagi Tatsuya
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 94 Issue: 6 Pages: 1794-1798
- DOI
  10.1246/bcsj.20210104
- NAID
  130008066569
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08235, KAKENHI-PROJECT-20K06987
[Journal Article] Intermolecular Interaction Analyses on SARS-CoV-2 Spike Protein Receptor Binding Domain and Human Angiotensin-Converting Enzyme 2 Receptor-Blocking Antibody/Peptide Using Fragment Molecular Orbital Calculation2021
- Author(s)
  Kazuki Watanabe, Chiduru Watanabe, Teruki Honma, Yu-Shi Tian, Yusuke Kawashima, Norihito Kawashita, Tatsuya Takagi, Kaori Fukuzawa
- Journal Title
  
  J. Phys. Chem. Lett.
  
  Volume: 12 Issue: 16 Pages: 4059-4066
- DOI
  10.1021/acs.jpclett.1c00663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06615, KAKENHI-PROJECT-20K06987
[Presentation] FMO 計算を用いた SARS-CoV-2 の RBD-中和抗体間の相互作用解析2020
- Author(s)
  渡邉一樹、川嶋裕介、福澤薫、渡邉千鶴、本間光貴、田雨時、川下理日人、高木達也
- Organizer
  第48回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-20K06987
[Presentation] 機械学習を用いた悪性症候群予測モデルの構築2019
- Author(s)
  望月麻衣、福戸康平、田雨時、高木達也
- Organizer
  第47回構造活性相関シンポジウム（熊本）
- Data Source
  KAKENHI-PROJECT-15KT0017
[Presentation] Prediction of Serious Adverse Events Using Machine Learning2018
- Author(s)
  Yushi-Tian, Hirotomo Moriwaki, Hiroaki Moriuchi, Satoshi Aoki, Nobuki Takayama, Norihito Kawashita, Takayuki Hibi, Tatsuya Takagi
- Organizer
  19th International Conference on Medicinal Chemistry and Multi Targeted Drug Delivery
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0017
[Presentation] 機械学習を用いた医薬品の有害事象の予測モデル構築の検討2018
- Author(s)
  Ni Tao、高木達也、日比孝之、望月麻衣、森脇寛智、田雨時
- Organizer
  第46回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-15KT0017

1. TAKAGI Tatsuya (80144517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 日比孝之 (80181113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 岡本晃典 (70437309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 川下理日人 (00423111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

TIAN Yushi 田 雨時

田 雨時 ティエン ユイシー

Research Projects

Research Products

Co-Researchers

Drug Design using Computational Chemistry and Multiple Supervised Machine Learning Systems based on Correlation between the Systems

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Modeling for Prediction of Serious Adverse Events Probabilities of Drug Candidates

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Computational <i>ab initio</i> interaction analyses between neutralizing antibody and SARS-CoV-2 variant spike proteins using the fragment molecular orbital method2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Intermolecular Interaction Analyses on SARS-CoV-2 Spike Protein Receptor Binding Domain and Human Angiotensin-Converting Enzyme 2 Receptor-Blocking Antibody/Peptide Using Fragment Molecular Orbital Calculation2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] FMO 計算を用いた SARS-CoV-2 の RBD-中和抗体間の相互作用解析2020

Author(s)

Organizer

Data Source

[Presentation] 機械学習を用いた悪性症候群予測モデルの構築2019

Author(s)

Organizer

Data Source

[Presentation] Prediction of Serious Adverse Events Using Machine Learning2018

Author(s)

Organizer

Data Source

[Presentation] 機械学習を用いた医薬品の有害事象の予測モデル構築の検討2018

Author(s)

Organizer

Data Source

TIAN Yushi 田雨時

田雨時ティエンユイシー