FUJITA Ryo 藤田諒

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Fujita Ryo 藤田諒

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Researcher Number	60770435
Other IDs	https://orcid.org/0000-0002-8392-0122
Affiliation (Current)	2025: 筑波大学, 医学医療系, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 筑波大学, 医学医療系, 助教
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / 0909:Sports sciences, physical education, health sciences, and related fields
Keywords	Principal Investigator 筋ジストロフィー / 骨格筋幹細胞 / 筋再生 / 骨格筋 / サルコペニア / 遺伝性筋疾患 / リプログラミング / 再生 / シングルセル / ヘテロジェネイティ … More / 遺伝子組換えマウス / Dusp27 / Dusp13 / 幹細胞不均一性 / MyoDノックインマウス / 幹細胞不均質性 / 放射線 / 微小環境 / 幹細胞移植 / シングルセル解析 / 幹細胞ニッシェ / 細胞移植 Less

筋疾患に対する幹細胞個別化医療の実現に向けた骨格筋幹細胞の運命制御機構の解明Principal Investigator
- Principal Investigator
  
  藤田諒
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Tsukuba
骨格筋幹細胞の新 (心) 機能Principal Investigator
- Principal Investigator
  
  藤田諒
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Tsukuba
Elucidation of Muscle Stem Cell Heterogeneity and Development of Regenerative TherapiesPrincipal Investigator
- Principal Investigator
  
  Fujita Ryo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Tsukuba
Elucidation of the Skeletal Muscle Microenvironment to Improve Transplantation Efficiency of Muscle Stem CellsPrincipal Investigator
- Principal Investigator
  
  Fujita Ryo
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0909:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Tsukuba

All 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] 医学のあゆみ(骨格筋幹細胞の幹細胞性維持機構-休止期維持メカニズムを中心に-)2023
- Author(s)
  藤田諒
- Total Pages
  2
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-21K17679
[Journal Article] High Throughput Screening of Mitochondrial Bioenergetics in Myoblasts and Differentiated Myotubes2023
- Author(s)
  Takeda Kohei、Takemasa Tohru、Fujita Ryo
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2640 Pages: 89-98
- DOI
  10.1007/978-1-0716-3036-5_7
- ISBN
  9781071630358, 9781071630365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K23283
[Journal Article] Generation of a MyoD knock-in reporter mouse line to study muscle stem cell dynamics and heterogeneity2023
- Author(s)
  Fujita Ryo、Mizuno Seiya、Sadahiro Taketaro、Hayashi Takuto、Sugasawa Takehito、Sugiyama Fumihiro、Ono Yusuke、Takahashi Satoru、Ieda Masaki
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 5 Pages: 106592-106592
- DOI
  10.1016/j.isci.2023.106592
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17679, KAKENHI-PROJECT-20K23283
[Journal Article] Direct Reprogramming Improves Cardiac Function and Reverses Fibrosis in Chronic Myocardial Infarction2023
- Author(s)
  Tani Hidenori、Sadahiro Taketaro、Yamada Yu、Isomi Mari、Yamakawa Hiroyuki、Fujita Ryo、Abe Yuto、Akiyama Tatsuya、Nakano Koji、Kuze Yuta、Seki Masahide、Suzuki Yutaka、Fujisawa Manabu、Sakata-Yanagimoto Mamiko、Chiba Shigeru、Fukuda Keiichi、Ieda Masaki
- Journal Title
  
  Circulation
  
  Volume: 147 Issue: 3 Pages: 223-238
- DOI
  10.1161/circulationaha.121.058655
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08072, KAKENHI-PROJECT-21K19471, KAKENHI-PROJECT-20K23283, KAKENHI-PROJECT-19K22613, KAKENHI-PROJECT-23K24326, KAKENHI-PROJECT-23K15140
[Journal Article] Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination2023
- Author(s)
  Sadaki Shunya、Fujita Ryo、Hayashi Takuto、Nakamura Ayano、Okamura Yui、Fuseya Sayaka、Hamada Michito、Warabi Eiji、Kuno Akihiro、Ishii Akiko、Muratani Masafumi、Okada Risa、Shiba Dai、Kudo Takashi、Takeda Shin’ichi、Takahashi Satoru
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 4 Pages: 112289-112289
- DOI
  10.1016/j.celrep.2023.112289
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17679, KAKENHI-PROJECT-22KJ0397, KAKENHI-PROJECT-22K06064
[Journal Article] The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool2022
- Author(s)
  Senechal Charlotte、Fujita Ryo、Jamet Solene、Maiga Arhamatoulaye、Dort Junio、Orfi Zakaria、Dumont Nicolas A.、Bouvier Michel、Crist Colin
- Journal Title
  
  Cell Reports
  
  Volume: 41 Issue: 7 Pages: 111645-111645
- DOI
  10.1016/j.celrep.2022.111645
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K23283
[Journal Article] The mitochondrial protein OPA1 regulates the quiescent state of adult muscle stem cells2022
- Author(s)
  Baker Nicole、Wade Steven、Triolo Matthew、Girgis John、Chwastek Damian、Larrigan Sarah、Feige Peter、Fujita Ryo、Crist Colin、Rudnicki Michael A.、Burelle Yan、Khacho Mireille
- Journal Title
  
  Cell Stem Cell
  
  Volume: 29 Issue: 9 Pages: 1315-1332.e9
- DOI
  10.1016/j.stem.2022.07.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17679
[Journal Article] Role of muscle stem cells in sarcopenia2021
- Author(s)
  Fujita Ryo
- Journal Title
  
  Sarcopenia: Molecular Mechanism and Treatment Strategies
  
  Volume: - Pages: 109-138
- DOI
  10.1016/b978-0-12-822146-4.00009-0
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17679
[Journal Article] Satellite cell expansion is mediated by P-eIF2α dependent Tacc3 translation2021
- Author(s)
  Fujita Ryo、Jamet Solene、Lean Graham、Cheng Harry Chun Man、Hebert Steven、Kleinman Claudia L.、Crist Colin
- Journal Title
  
  Development
  
  Volume: 148
- DOI
  10.1242/dev.194480
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K23283
[Journal Article] Nuclear factor E2-related factor 2 (NRF2) deficiency accelerates fast fibre type transition in soleus muscle during space flight2021
- Author(s)
  Hayashi Takuto, Kudo Takashi, Fujita Ryo, Fujita Shin-ichiro, Tsubouchi Hirona, Fuseya Sayaka, Suzuki Riku, Hamada Michito, Okada Risa, Muratani Masafumi, Shiba Dai, Suzuki Takafumi, Warabi Eiji, Yamamoto Masayuki, Takahashi Satoru
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 787-787
- DOI
  10.1038/s42003-021-02334-4
- NAID
  120007185357
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03234, KAKENHI-PROJECT-20K23283
[Journal Article] Direct reprogramming with Sendai virus vectors repaired infarct hearts at the chronic stage2021
- Author(s)
  Isomi Mari、Sadahiro Taketaro、Fujita Ryo、Abe Yuto、Yamada Yu、Akiyama Tatsuya、Mizukami Hiroaki、Shu Tsugumine、Fukuda Keiichi、Ieda Masaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 560 Pages: 87-92
- DOI
  10.1016/j.bbrc.2021.04.121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04179, KAKENHI-PROJECT-19K22613, KAKENHI-PROJECT-21K19471, KAKENHI-PROJECT-20K23283
[Journal Article] Overexpression of Gata4, Mef2c, and Tbx5 Generates Induced Cardiomyocytes Via Direct Reprogramming and Rare Fusion in the Heart2021
- Author(s)
  Isomi Mari、Sadahiro Taketaro、Yamakawa Hiroyuki、Fujita Ryo、Yamada Yu、Abe Yuto、Murakata Yoshiko、Akiyama Tatsuya、Shu Tsugumine、Mizukami Hiroaki、Fukuda Keiichi、Ieda Masaki
- Journal Title
  
  Circulation
  
  Volume: 143 Issue: 21 Pages: 2123-2125
- DOI
  10.1161/circulationaha.120.052799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04179, KAKENHI-PROJECT-18K08047, KAKENHI-PROJECT-19K22613, KAKENHI-PROJECT-21K19471, KAKENHI-PROJECT-20K23283
[Journal Article] Direct Reprogramming as a Novel Approach for Cardiovascular Regeneration2021
- Author(s)
  Fujita Ryo、Sadahiro Taketaro、Ieda Masaki
- Journal Title
  
  Pediatric Cardiology and Cardiac Surgery
  
  Volume: 37 Issue: 1 Pages: 10-17
- DOI
  10.9794/jspccs.37.10
- NAID
  130008117314
- ISSN
  0911-1794, 2187-2988
- Year and Date
  2021-04-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K23283
[Presentation] サルコペニア克服に向けた骨格筋線維タイプ制御機構の解明2023
- Author(s)
  藤田諒; 定木駿弥; 林卓杜; 辻諒介; 工藤崇; 高橋智
- Organizer
  第10回日本サルコペニア・フレイル学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K23283
[Presentation] サルコペニア克服に向けた骨格筋線維タイプ制御機構の解明2023
- Author(s)
  藤田諒; 定木駿弥; 林卓杜; 辻諒介; 工藤崇; 高橋智
- Organizer
  第10回日本サルコペニア・フレイル学会大会/
- Invited
- Data Source
  KAKENHI-PROJECT-21K17679
[Presentation] これであなたもネズミのように走れる!? 肉質制御機構の解明2023
- Author(s)
  藤田諒
- Organizer
  The 153rd Scienc-ome
- Invited
- Data Source
  KAKENHI-PROJECT-20K23283
[Presentation] これであなたもネズミのように走れる!? 肉質制御機構の解明2023
- Author(s)
  藤田諒
- Organizer
  The 153rd Scienc-ome
- Invited
- Data Source
  KAKENHI-PROJECT-21K17679
[Presentation] Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination2023
- Author(s)
  Fujita Ryo; Sadaki Shunya; Takahashi Satoru
- Organizer
  1st Symposium on "Skeletal muscle cells in Growth and Disease"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17679
[Presentation] MyoD ノックインマウスによる骨格筋幹細胞の運命制御機構の解明2023
- Author(s)
  藤田諒
- Organizer
  第9回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17679
[Presentation] MyoD ノックインマウスによる骨格筋幹細胞の運命制御機構の解明2023
- Author(s)
  藤田諒
- Organizer
  第9回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-20K23283
[Presentation] Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination2023
- Author(s)
  Fujita Ryo; Sadaki Shunya; Takahashi Satoru
- Organizer
  1st Symposium on "Skeletal muscle cells in Growth and Disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K23283
[Presentation] 骨格筋幹細胞と微小環境をつなぐ接着型Gタンパク質共役型受容体の役割2022
- Author(s)
  藤田諒
- Organizer
  第8回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-20K23283
[Presentation] 接着型Gタンパク質共役型受容体による骨格筋幹細胞維持メカニズム2022
- Author(s)
  藤田諒
- Organizer
  第8回 Matricell フォーラム
- Data Source
  KAKENHI-PROJECT-20K23283
[Presentation] Lunar Gravity Prevents Skeletal Muscle Atrophy, But Not Muscle Fiber Type Transition2022
- Author(s)
  HAYASHI, Takuto;Fujita, Ryo;Okada, Risa;Hamada, Michito;Suzuki, Riku;Fuseya, Sayaka;Leckey, James;Kanai, Maho;Inoue, Yuri;Sadaki, Shunya;Nakamura, Ayano;Okamura, Yui;Abe, Chikara;Morita, Hironobu;Muratani, Masafumi;Kudo, Takashi;Shiba, Dai;Takahashi, Satoru
- Organizer
  15th Annual Wernher von Braun Memorial Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17679
[Presentation] 大Maf転写因子は速筋線維を制御する主要な因子である2022
- Author(s)
  定木駿弥;藤田, 諒;林卓杜;中村綾乃;岡村結;布施谷清香;濱田理人;蕨栄治;久野朗広;村谷匡史;岡田理沙;芝大;工藤崇;高橋, 智
- Organizer
  第8回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17679
[Presentation] 速筋線維の形成に不可欠な新規制御因子である大Maf転写因子の機能解析2022
- Author(s)
  定木駿弥; 藤田諒; 林卓杜; 中村綾乃; 岡村結; 布施谷清香; 濱田理人; 蕨栄治; 久野朗広; 村谷匡史; 岡田理沙;芝大; 工藤崇;高橋智
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K17679
[Presentation] Direct In Vivo Reprogramming of Fibroblasts into Cardiomyocytes as a Therapeutic Strategy for Heart Failure2021
- Author(s)
  Taketaro Sadahiro, Yu Yamada, Fujita Ryo, Yuto Abe, Tatsuya Akiyama, Masaki Ieda
- Organizer
  ISSCR/JSRM 2021 Tokyo International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17679
[Presentation] 宇宙環境を用いた骨格筋重力応答の解析2021
- Author(s)
  高橋智、工藤崇、林卓杜、藤田諒
- Organizer
  第7回日本筋学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K17679
[Presentation] 新規遺伝子改変マウスによる骨格筋幹細胞の運命制御機構の解明2021
- Author(s)
  藤田諒、水野聖哉、貞廣威太郎、杉山文博、高橋智、家田真樹
- Organizer
  第7回日本筋学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K17679
[Presentation] サルコペニア・筋疾患治療へ向けた骨格筋幹細胞の可能性2021
- Author(s)
  藤田諒
- Organizer
  BioJapan2021
- Data Source
  KAKENHI-PROJECT-20K23283
[Presentation] Gタンパク質共役型受容体における骨格筋幹細胞の幹細胞性維持機構2021
- Author(s)
  藤田諒
- Organizer
  第76回日本体力医学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K23283
[Presentation] 骨格筋幹細胞の機能とサルコペニア2020
- Author(s)
  藤田諒
- Organizer
  第7回日本サルコペニア・フレイル学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K23283

1. 顧文超 (10967318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 菅澤威仁 (60821840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 貞廣威太郎 (60571130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 村谷匡史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 家田真樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

FUJITA Ryo 藤田 諒

Fujita Ryo 藤田 諒

Research Projects

Research Products

Co-Researchers

筋疾患に対する幹細胞個別化医療の実現に向けた骨格筋幹細胞の運命制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

骨格筋幹細胞の新 (心) 機能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of Muscle Stem Cell Heterogeneity and Development of Regenerative TherapiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the Skeletal Muscle Microenvironment to Improve Transplantation Efficiency of Muscle Stem CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 医学のあゆみ(骨格筋幹細胞の幹細胞性維持機構-休止期維持メカニズムを中心に-)2023

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] High Throughput Screening of Mitochondrial Bioenergetics in Myoblasts and Differentiated Myotubes2023

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Generation of a MyoD knock-in reporter mouse line to study muscle stem cell dynamics and heterogeneity2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Direct Reprogramming Improves Cardiac Function and Reverses Fibrosis in Chronic Myocardial Infarction2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The mitochondrial protein OPA1 regulates the quiescent state of adult muscle stem cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of muscle stem cells in sarcopenia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Satellite cell expansion is mediated by P-eIF2α dependent Tacc3 translation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear factor E2-related factor 2 (NRF2) deficiency accelerates fast fibre type transition in soleus muscle during space flight2021

Author(s)

Journal Title

DOI

NAID

FUJITA Ryo 藤田諒

Fujita Ryo 藤田諒