Arima Mitsuru 有馬充

Researcher Number	60772845
Affiliation (based on the past Project Information) *help	2020 – 2023: 九州大学, 大学病院, 学術研究員 2017 – 2019: 九州大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56060:Ophthalmology-related / Ophthalmology Except Principal Investigator Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator 糖尿病黄斑浮腫 / 分子標的治療 / ROCK / 抗VEGF治療 / 糖尿病網膜症 / 密着結合 / 血液網膜関門 Except Principal Investigator リプログラミング / 再生医療 / 網膜再生医療 … More / 自然炎症 / 網膜前駆細胞 / 低分子化合物 / 網膜 / 急性期治療 / 視細胞 / ロドプシン / 増殖硝子体網膜症 / 糖尿病網膜症 / 網膜前膜 / シングルセル解析 / 眼内増殖性疾患 / OCT angiography / イメージング / 血管新生 / 網膜虚血 / 増殖糖尿病網膜症 / 線維化 / レーザー誘発CNV)モデルマウス / 網膜下線維化 / 線維化モデルマウスにおけるagrin / 加齢黄斑変性患者における線維化率 / 線維化モデルマウス / 線維化阻害 / agrin / 網膜下線維化病変 / 加齢黄斑変性 / 網膜自己再生 / 眼炎症 / 自然再生 Less

Acute retinal regenerative medicine with low molecular weight cocktail
- Principal Investigator
  
  Sonoda Koh-Hei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyushu University
Activity biomarker search for intraocular proliferative tissue at the single cell level
- Principal Investigator
  
  Nakao Shintaro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  National Hospital Organization, Kyushu Medical Center (Clinical Institute)
Inhibition and treatment for subretinal fibrosis that occurs severe visual impairment in patients with age-related macular degeneration
- Principal Investigator
  
  Shiose Satomi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyushu University
Development of a novel treatment for anti-VEGF resistant diabetic macular edema using ROCK inhibitorPrincipal Investigator
- Principal Investigator
  
  Arima Mitsuru
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyushu University
The induction of retinal progenitor cells by the control of natural inflammation
- Principal Investigator
  
  Sonoda Koh-Hei
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyushu University
Novel treatment for diabetic macular edema not dependent on anti-VEGF therapyPrincipal Investigator
- Principal Investigator
  
  Arima Mitsuru
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyushu University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Rhodopsin-positive cell production by intravitreal injection of small molecule compounds in mouse models of retinal degeneration2023
- Author(s)
  Fujii Yuya、Arima Mitsuru、Murakami Yusuke、Sonoda Koh-Hei
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 2 Pages: e0282174-e0282174
- DOI
  10.1371/journal.pone.0282174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03094
[Journal Article] Identifying Hyperreflective Foci in Diabetic Retinopathy via VEGF-Induced Local Self-Renewal of CX3CR1+ Vitreous Resident Macrophages2022
- Author(s)
  Yamaguchi Muneo、Nakao Shintaro、Wada Iori、Matoba Tetsuya、Arima Mitsuru、Kaizu Yoshihiro、Shirane Mariko、Ishikawa Keijiro、Nakama Takahito、Murakami Yusuke、Mizuochi Masaharu、Shiraishi Wataru、Yamasaki Ryo、Hisatomi Toshio、Ishibashi Tatsuro、Shibuya Masabumi、Stitt Alan W.、Sonoda Koh-Hei
- Journal Title
  
  Diabetes
  
  Volume: 71 Issue: 12 Pages: 2685-2701
- DOI
  10.2337/db21-0247
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09829, KAKENHI-PROJECT-21K16897
[Journal Article] Hyperreflective Membrane at the Vitreoretinal Interface in Diabetic Macular Edema: A Finding in Ultra-High-Resolution Optical Coherence Tomography2022
- Author(s)
  Wada Iori、Nakao Shintaro、Arima Mitsuru、Ishikawa Keijiro、Yamaguchi Muneo、Kaizu Yoshihiro、Sekiryu Haruka、Mori Kenichiro、Kiyohara Kohei、Takeda Atsunobu、Ishibashi Tatsuro、Sadda SriniVas R.、Sonoda Koh-Hei
- Journal Title
  
  Translational Vision Science & Technology
  
  Volume: 11 Issue: 9 Pages: 21-21
- DOI
  10.1167/tvst.11.9.21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09829, KAKENHI-PROJECT-21K16897
[Journal Article] Morphology and fluorescein leakage in diabetic retinal microaneurysms: a study using multiple en face OCT angiography image averaging2022
- Author(s)
  Fukuda Yosuke、Nakao Shintaro、Kaizu Yoshihiro、Arima Mitsuru、Shimokawa Sakurako、Wada Iori、Yamaguchi Muneo、Takeda Atsunobu、Sonoda Koh-Hei
- Journal Title
  
  Graefe's Archive for Clinical and Experimental Ophthalmology
  
  Volume: 260 Issue: 11 Pages: 3517-3523
- DOI
  10.1007/s00417-022-05713-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09829, KAKENHI-PROJECT-21K16897
[Journal Article] Volumetric Three-Dimensional Optical Coherence Tomography Angiography of Retinal Neovascularization in Proliferative Diabetic Retinopathy2021
- Author(s)
  Nakao Shintaro、Kaizu Yoshihiro、Horie Juun、Wada Iori、Arima Mitsuru、Fukuda Yosuke、Ishikawa Keijiro、Sonoda Koh-Hei
- Journal Title
  
  RETINAL Cases & Brief Reports
  
  Volume: - Issue: 3 Pages: 315-320
- DOI
  10.1097/icb.0000000000001183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09828, KAKENHI-PROJECT-20K09829
[Journal Article] Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1+ Macrophage Infiltration.2021
- Author(s)
  Wada I, Nakao S, Yamaguchi M, Kaizu Y, Arima M, Sawa S, Sonoda KH.
- Journal Title
  
  Invest Ophthalmol Vis Sci .
  
  Volume: 62 Issue: 13 Pages: 17-17
- DOI
  10.1167/iovs.62.13.17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09829
[Journal Article] Vitreous levels of interleukin-35 as a prognostic factor in B-cell vitreoretinal lymphoma2020
- Author(s)
  Takeda Atsunobu、Hasegawa Eiichi、Nakao Shintaro、Ishikawa Keijiro、Murakami Yusuke、Hisatomi Toshio、Arima Mitsuru、Yawata Nobuyo、Oda Yoshinao、Kimura Kazuhiro、Yoshikawa Hiroshi、Sonoda Koh-Hei
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 15715-15715
- DOI
  10.1038/s41598-020-72962-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09828, KAKENHI-PROJECT-20K09829, KAKENHI-PROJECT-18K09467, KAKENHI-PROJECT-18K09471
[Journal Article] Claudin-5 Redistribution Induced by Inflammation Leads to Anti-VEGF-Resistant Diabetic Macular Edema.2020
- Author(s)
  Arima M, Nakao S, Yamaguchi M, Feng H, Fujii Y, Shibata K, Wada I, Kaizu Y, Ahmadieh H, Ishibashi T, Stitt AW, Sonoda KH.
- Journal Title
  
  Diabetes
  
  Volume: 69 Issue: 5 Pages: 981-999
- DOI
  10.2337/db19-1121
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18846, KAKENHI-PROJECT-17K11456
[Journal Article] Optical Coherence Tomography Angiography of Choroidal Neovascularization in Immune Choroiditis Following Acute Retinal Necrosis2020
- Author(s)
  Nakamura S, Nakao S, Shiose S, Kohno RI, Hasegawa E,Sonoda KH
- Journal Title
  
  Eur J Ophthalmol
  
  Volume: - Issue: 1 Pages: 4185-4185
- DOI
  10.1038/s41598-021-83334-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09829, KAKENHI-PROJECT-19K18846
[Journal Article] Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases2017
- Author(s)
  Yamaguchi Muneo、Nakao Shintaro、Arima Mitsuru、Wada Iori、Kaizu Yoshihiro、Hao Feng、Yoshida Shigeo、Sonoda Koh-hei
- Journal Title
  
  Journal of Ophthalmology
  
  Volume: 2017 Pages: 1-8
- DOI
  10.1155/2017/8543592
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11456, KAKENHI-PROJECT-17K16997
[Journal Article] Optical Coherence Tomography Angiography Reveals Spatial Bias of Macular Capillary Dropout in Diabetic Retinopathy2017
- Author(s)
  Kaizu Yoshihiro、Nakao Shintaro、Yoshida Shigeo、Hayami Takehito、Arima Mitsuru、Yamaguchi Muneo、Wada Iori、Hisatomi Toshio、Ikeda Yasuhiro、Ishibashi Tatsuro、Sonoda Koh-Hei
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 58 Issue: 11 Pages: 4889-4889
- DOI
  10.1167/iovs.17-22306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11456, KAKENHI-PROJECT-17K16997
[Presentation] OCT angiographyのFAZ測定に対するAIによるDenoise処理2020
- Author(s)
  福田洋輔, 中尾新太郎, 海津嘉弘, 和田伊織, 有馬充, 石川桂二郎, 園田康平
- Organizer
  第１回日本眼科ＡＩ学会総会
- Data Source
  KAKENHI-PROJECT-20K09829
[Presentation] ボリューメトリック3次元 OCT angiographyを用いた増殖糖尿病網膜症における網膜新生血管評価2020
- Author(s)
  田洋輔, 中尾新太郎, 海津嘉弘, 和田伊織, 有馬充, 石川桂二郎, 園田康平
- Organizer
  日本糖尿病眼学会
- Data Source
  KAKENHI-PROJECT-20K09829
[Presentation] Claudin-5 Redistribution Induced by Inflammation Leads to Anti-VEGF Resistant Diabetic Macular Edema2020
- Author(s)
  有馬　充
- Organizer
  第26回日本糖尿病眼学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K18846
[Presentation] 糖尿病網膜症における毛細血管瘤の疎密と臨床的意義の関連性2020
- Author(s)
  中尾新太郎, 海津嘉弘, 和田伊織, 有馬充, 山口宗男, 石川桂二郎, 園田康平
- Organizer
  日本糖尿病眼学会
- Data Source
  KAKENHI-PROJECT-20K09829
[Presentation] 低分子化合物投与によるアストロサイトから網膜神経細胞へのリプログラミング2019
- Author(s)
  藤井裕也, 有馬充, 下川翔太郎, 村上祐介, 園田康平
- Organizer
  第18回再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18H02956
[Presentation] 糖尿病黄斑浮腫におけるcluadin-5発現調節へのROCK阻害剤リパスジルの効果2018
- Author(s)
  有馬充、中尾新太郎、馮浩、山口宗男、海津嘉弘、和田伊織、吉田茂生、園田康平
- Organizer
  日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-17K16997
[Presentation] 糖尿病網膜症の毛細血管瘤検出における加算平均OCT angiographyの有用性2018
- Author(s)
  海津嘉弘、中尾新太郎、有馬充、和田伊織、岸本淳司、吉富景子、杉野迪子、橋口直哉、平島昂太、園田康平
- Organizer
  日本網膜硝子体学会総会
- Data Source
  KAKENHI-PROJECT-17K16997
[Presentation] Impact of a ROCK inhibitor ripasudil on distribution of claudin-5 in vascular endothelial cells in diabetic retinopathy2018
- Author(s)
  Arima M、Nakao S、Feng H、Yamaguchi M、Shibata K、Kaizu Y、Wada I、Yoshida S、Sonoda KH
- Organizer
  The Association for Research in Vision and Ophthalmology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16997
[Presentation] 糖尿病網膜症におけるOCT angiographyの網膜血管描出再現性は病期により異なる2018
- Author(s)
  海津嘉弘、中尾新太郎、有馬充、和田伊織、石川桂二郎、吉富景子、杉野迪子、橋口直哉、平島昂太、園田康平
- Organizer
  眼循環学会
- Data Source
  KAKENHI-PROJECT-17K16997
[Presentation] Detection capability of microaneurysms in diabetic retinopathy eyes improves using averaged optical coherence tomography angiography image2018
- Author(s)
  Kaizu Y、Nakao S、Arima M、Wada I、Yoshitomi K、Sugino M、Hashiguchi N、Hirashima K，Sonoda KH
- Organizer
  Asia-Pacific Vitreo-retina Society (APVRS) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16997
[Presentation] OCTAによる網膜灌流密度の空間的パターンは糖尿病網膜症の検出に有用である2017
- Author(s)
  海津嘉弘、中尾新太郎、吉田茂生、有馬充、藤原康太、和田伊織、山口宗男、岸本淳司、石橋達朗、園田康平
- Organizer
  日本眼循環学会
- Data Source
  KAKENHI-PROJECT-17K16997
[Presentation] OCTAによる網膜灌流密度は糖尿病網膜症の無灌流領域検出に有用である2017
- Author(s)
  石龍悠、中尾新太郎、海津嘉弘、吉田茂生、有馬充、和田伊織、山口宗男、石橋達朗、園田康平
- Organizer
  日本眼循環学会
- Data Source
  KAKENHI-PROJECT-17K16997
[Presentation] 糖尿病網膜症の網膜血管における claudin-5 発現調節機構2017
- Author(s)
  有馬充、園田康平
- Organizer
  日本眼循環学会
- Data Source
  KAKENHI-PROJECT-17K16997

1. Sonoda Koh-Hei (10294943)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. 石川桂二郎 (00795304)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. 村上祐介 (50634995)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 中島欽一 (80302892)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Shiose Satomi (90644758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Nakao Shintaro (50583027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
7. 池田康博 (20380389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 清木誠 (50226619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 吉田茂生 (50363370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 秋山雅人 (10757686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 久冨智朗 (50404033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山口宗男 (50848017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. 澤新一郎 (80611756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 武田篤信 (40560313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Arima Mitsuru 有馬 充

Research Projects

Research Products

Co-Researchers

Acute retinal regenerative medicine with low molecular weight cocktail

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Activity biomarker search for intraocular proliferative tissue at the single cell level

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Inhibition and treatment for subretinal fibrosis that occurs severe visual impairment in patients with age-related macular degeneration

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel treatment for anti-VEGF resistant diabetic macular edema using ROCK inhibitorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The induction of retinal progenitor cells by the control of natural inflammation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel treatment for diabetic macular edema not dependent on anti-VEGF therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Rhodopsin-positive cell production by intravitreal injection of small molecule compounds in mouse models of retinal degeneration2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identifying Hyperreflective Foci in Diabetic Retinopathy via VEGF-Induced Local Self-Renewal of CX3CR1+ Vitreous Resident Macrophages2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hyperreflective Membrane at the Vitreoretinal Interface in Diabetic Macular Edema: A Finding in Ultra-High-Resolution Optical Coherence Tomography2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Morphology and fluorescein leakage in diabetic retinal microaneurysms: a study using multiple en face OCT angiography image averaging2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Volumetric Three-Dimensional Optical Coherence Tomography Angiography of Retinal Neovascularization in Proliferative Diabetic Retinopathy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1+ Macrophage Infiltration.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vitreous levels of interleukin-35 as a prognostic factor in B-cell vitreoretinal lymphoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Claudin-5 Redistribution Induced by Inflammation Leads to Anti-VEGF-Resistant Diabetic Macular Edema.2020

Author(s)

Journal Title

DOI

Data Source

Arima Mitsuru 有馬充

[Presentation] 糖尿病網膜症におけるOCT angiographyの網膜血管描出再現性は病期により異なる2018