HARA SHOKO 原祥子

… Alternative Names

Hara Shoko 原祥子

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Researcher Number	60772879
Other IDs	https://orcid.org/0000-0003-1097-2738
Affiliation (Current)	2025: 東京科学大学, 東京科学大学病院, 助教 2025: 順天堂大学, 医学部, 非常勤助手
Affiliation (based on the past Project Information) *help	2021 – 2023: 東京医科歯科大学, 東京医科歯科大学病院, 助教 2020: 東京医科歯科大学, 医学部附属病院, 助教 2019: 東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師 2016 – 2018: 順天堂大学, 医学部, 非常勤助手
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery
Keywords	Principal Investigator 脳血流障害 / もやもや病 / MRI / 脳脊髄液 / 認知機能障害 / 脳微細構造 / 拡散MRI / 血液脳関門 / Glymphatic system / 小児 … More / 軸索 / ミエリン / 血行再建術 / 神経細胞障害 / ミエリンイメージング / 脳血管障害 / Neurofluid / 磁気共鳴画像 / 脳神経疾患 / 脳循環代謝 / 高次脳機能障害 Less

GLymphatic system and blood brain barrier dysfunction evaluated by MRI in patients with moyamoya diseasePrincipal Investigator
- Principal Investigator
  
  原祥子
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tokyo Medical and Dental University
Brain microstructural correlates of neurocognitive dysfunction in pediatric and adult Moyamoya disease elucidated from Myelin imaging and diffusion MRIPrincipal Investigator
- Principal Investigator
  
  Hara Shoko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tokyo Medical and Dental University
Clinical significance of diffusion MRI in patients with Moyamoya diseasePrincipal Investigator
- Principal Investigator
  
  Hara Shoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Juntendo University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Increased Parenchymal Free Water May Be Decreased by Revascularization Surgery in Patients with Moyamoya Disease2024
- Author(s)
  Hara Shoko、Hori Masaaki、Kamagata Koji、Andica Christina、Inaji Motoki、Tanaka Yoji、Aoki Shigeki、Nariai Tadashi、Maehara Taketoshi
- Journal Title
  
  MRMS
  
  Volume: 23 Issue: 4 Pages: 405-416
- DOI
  10.2463/mrms.mp.2022-0146
- ISSN
  1347-3182, 1880-2206
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18406, KAKENHI-PROJECT-22H04926
[Journal Article] Diffusivity Along the Perivascular Space is Decreased and Related to Hypoperfusion in Adult Moyamoya disease2023
- Author(s)
  Hara Shoko、Kikuta Junko、Takabayashi Kaito、Kamagata Koji、Hayashi Shihori、Inaji Motoki、Tanaka Yoji、Hori Masaaki、Ishii Kenji、Nariai Tadashi、Taoka Toshiaki、Naganawa Shinji、Aoki Shigeki、Maehara Taketoshi
- Journal Title
  
  ResearchSquare
  
  Volume: 1 Pages: 1-1
- DOI
  10.21203/rs.3.rs-3411760/v1
- Data Source
  KAKENHI-PROJECT-23K08514
[Journal Article] Myelin and Axonal Damage in Normal-Appearing White Matter in Patients with Moyamoya Disease2020
- Author(s)
  Hara, S. Hori, M. Hagiwara, A. Tsurushima, Y. Tanaka, Y. Maehara, T. Aoki, S. Nariai, T.
- Journal Title
  
  American Journal of Neuroradiology
  
  Volume: 9 Pages: 1618-1624
- DOI
  10.3174/ajnr.a6708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18406, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-18H02772
[Journal Article] Regression of White Matter Hyperintensity after Indirect Bypass Surgery in a Patient with Moyamoya Disease2019
- Author(s)
  Hara S, Hori M, Inaji M, Maehara T, Aoki S, Nariai T
- Journal Title
  
  MRMS
  
  Volume: 18 Issue: 4 Pages: 247-248
- DOI
  10.2463/mrms.ci.2018-0088
- NAID
  130007728806
- ISSN
  1347-3182, 1880-2206
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19995, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-17K10886
[Journal Article] Unraveling Specific Brain Microstructural Damage in Moyamoya Disease Using Diffusion Magnetic Resonance Imaging and Positron Emission Tomography.2019
- Author(s)
  Hara S, Hori M, Ueda R, Hayashi S, Inaji M, Tanaka Y, Maehara T, Ishii K, Aoki S, Nariai T
- Journal Title
  
  Journal of Stroke and Cerebrovascular diseases
  
  Volume: 28 Issue: 4 Pages: 1113-1125
- DOI
  10.1016/j.jstrokecerebrovasdis.2018.12.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19995, KAKENHI-PROJECT-17K10886, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-18H02772
[Journal Article] Intravoxel Incoherent Motion Perfusion in Patients with Moyamoya Disease: Comparison with 15O-gas Positron Emission Tomograph2019
- Author(s)
  Hara S, Hori M, Ueda R, Hagiwara A, Hayashi S, ,Inaji M, Tanaka Y, Maehara T, Ishii K, Aoki S, Nariai T
- Journal Title
  
  Acta Radiologica Open
  
  Volume: (in press)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19995
[Journal Article] Microstructural Damage in Normal-Appearing Brain Parenchyma and Neurocognitive Dysfunction in Adult Moyamoya Disease2018
- Author(s)
  Hara Shoko、Hori Masaaki、Murata Syo、Ueda Ryo、Tanaka Yoji、Inaji Motoki、Maehara Taketoshi、Aoki Shigeki、Nariai Tadashi
- Journal Title
  
  Stroke
  
  Volume: 49 Issue: 10 Pages: 2504-2507
- DOI
  10.1161/strokeaha.118.022367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10886, KAKENHI-PROJECT-16K19995, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-18H02772
[Presentation] もやもや病の脳血流障害に伴う CNS-interstitial fluidopathyと血行再建術後変化2023
- Author(s)
  原祥子
- Organizer
  第51回日本磁気共鳴医学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K08514
[Presentation] Do adult patients with moyamoya disease have glymphatic system dysfunction? - evaluation using diffusion along perivascular space2023
- Author(s)
  Hara S, Kikuta J, Takabayashi K, Kamagata K, Hayashi S, Inaji M, Tanaka Y, Hori M, Ishii K, Nariai T, Taoka T, Naganawa S, Aoki S, Maehara T
- Organizer
  ISMRM2023
- Data Source
  KAKENHI-PROJECT-23K08514
[Presentation] 血行再建術がもやもや病の脈絡叢に与える影響2023
- Author(s)
  原祥子、菊田潤子、高林海斗、陳紅かい、鎌形康司、堀正明、田中洋次、成相直、青木茂樹、前原健寿
- Organizer
  第51回日本磁気共鳴医学会大会
- Data Source
  KAKENHI-PROJECT-23K08514
[Presentation] 小児もやもや病ー基本から最新知見までー2023
- Author(s)
  原祥子
- Organizer
  TMDU小児神経グループ勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-23K08514
[Presentation] ALPS indexを用いたもやもや病患者におけるGlymphatic system評価の試み2022
- Author(s)
  原祥子, 菊田潤子, 高林海斗, 鎌形康司, 田中洋次, 成相直, 堀正明, 田岡俊昭, 長縄慎二, 青木茂樹, 前原健寿
- Organizer
  第51回日本神経放射線学会
- Data Source
  KAKENHI-PROJECT-19K18406
[Presentation] Glymphatic system activity may be disrupted in moyamoya disease: the diffusion tensor image analysis along the perivascular space (DTI-ALPS) study2022
- Author(s)
  Shoko Hara, Junko Kikuta, Kaito Takabayashi, Koji Kamagata, Shihori Hayashi, Motoki Inaji, Yoji Tanaka, Masaaki Hori, Kenji Ishii, Tadashi Nariai, Toshiaki Taoka, Shinji Naganawa, Shigeki Aoki, Taketoshi Maehara
- Organizer
  ICMRI 2022 (10th International Congress on MRI) & 27th Annual Scientific Meeting of KSMRM (the Korean Society of Magnetic Resonance in Medicine)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18406
[Presentation] Disrupted cerebral microstructural integrity revealed by diffusion MRI in adult moyamoya disease2022
- Author(s)
  Shoko Hara
- Organizer
  ICMRI 2022 (10th International Congress on MRI) & 27th Annual Scientific Meeting of KSMRM (the Korean Society of Magnetic Resonance in Medicine)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18406
[Presentation] Longitudinal analysis revealed increased parenchymal free water may be relieved by revascularization surgery in patients with moyamoya disease2021
- Author(s)
  Shoko Hara, Masaaki Hori, Yoji Tanaka, Taketoshi Maehara, Shigeki Aoki, Tadashi Nariai
- Organizer
  the 2021 ISMRM & SMRT Annual Meeting, An Online Experience
- Data Source
  KAKENHI-PROJECT-19K18406
[Presentation] もやもや病の血行再建術後にみられる拡散MRI信号変化は水成分減少に由来する2021
- Author(s)
  原祥子, 堀正明, 田中洋次, 前原健寿, 青木茂樹, 成相直
- Organizer
  第50回日本神経放射線学会
- Data Source
  KAKENHI-PROJECT-19K18406
[Presentation] もやもや病患者における血行再建術後の脳微細構造と認知機能の変化2020
- Author(s)
  原祥子, 堀正明, 田中洋次, 前原健寿, 青木茂樹, 成相直
- Organizer
  第79回日本脳神経外科学会総会
- Data Source
  KAKENHI-PROJECT-19K18406
[Presentation] Correlation between brain microstructure revealed by Neurite Orientation Dispersion and Density Imaging and cerebral hemodynamics and metabolism measured with positron emission tomography in patients with moyamoya disease2019
- Author(s)
  Hara S, Nariai T, Murata S, Tsuruta K, Tanaka Y, Hori M, Maehara T, Aoki S
- Organizer
  Neuroscience 2017
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] Neurite orientation dispersion and density imaging revealed the brain microstructural ischemic damage of moyamoya disease2019
- Author(s)
  Hara S, Nariai T, Murata S, Tsuruta K, Tanaka Y, Hori M, Maehara T, Aoki S
- Organizer
  Neuroscience 2016
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] 新規拡散MRI・NODDI法によるもやもや病の脳微細構造の検討2019
- Author(s)
  原祥子、成相直、堀正明、村田渉、上田亮、中澤美咲、田中洋次、前原健寿、青木茂樹
- Organizer
  第46回日本神経放射線学会 2017
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] NODDI revealed the brain microstructural damage in patients with moyamoya NODDI revealed the brain microstructural damage in patients with moyamoya disease2019
- Author(s)
  Hara S, Hori M, Murata S, Ueda R, Nakazawa M, Tanaka Y, Maehara T, Aoki S, Nariai T
- Organizer
  ISMRM 25th Anuual Meeting & Exhibition 2017
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] Correlation of Intravoxel Incoherent Motion and 15O-gas PET in patients with Moyamoya disease2019
- Author(s)
  Hara S, Hori M, Ueda R, Tanaka Y, Maehara T, Ishii K, Nariai T, Aoki S.
- Organizer
  5th International Congress on Magnetic Resonance Imaging (ICMRI 2017) and 22nd Scientific Meeting of KSMRM
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] Microstructural imaging using diffusion MRI in patients with Moyamoya disease2019
- Author(s)
  Hara S, Nariai T
- Organizer
  Research meeting with Neuroradiology, Stanford University 2017
- Invited
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] pCASLとNODDIを用いたもやもや病の脳血流および微細構造の評価2019
- Author(s)
  原祥子、田中洋次、稲次基希、石井賢二、前原健寿、堀正明、青木茂樹、成相直
- Organizer
  第45回日本神経放射線学会 2016
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] 新規拡散MRI・NODDI法によるもやもや病の脳微細構造の検討2019
- Author(s)
  原祥子、成相直、堀正明、村田渉、上田亮、中澤美咲、田中洋次、前原健寿、青木茂樹
- Organizer
  第46回日本脳神経CI学学会 2017
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] 成人もやもや病患者の脳微細構造障害と認知機能障害2019
- Author(s)
  原　祥子
- Organizer
  第48回日本神経放射線学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] 新規拡散MRI・NODDI法によるもやもや病の脳微細構造の検討2019
- Author(s)
  原祥子、成相直、堀正明、村田渉、上田亮、中澤美咲、田中洋次、青木茂樹、前原健寿
- Organizer
  第42回日本脳卒中学会学術集会 2017
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] Myelin imaging may reveal microstructural damage caused by chronic ischemia correlated with neurocognitive dysfunction in patients with moyamoya disease2018
- Author(s)
  Hara S, Hori M, Tsurushima Y, Tanaka Y, Maehara T, Aoki S, and Nariai T.
- Organizer
  Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] Neurite Orientation Dispersion and Density Imaging (NODDI) revealed the brain microstructural ischemic damage in patients with moyamoya disease2017
- Author(s)
  Shoko Hara, Masaaki Hori, Syo Murata, Ryo Ueda, Misaki Nakazawa, Yoji Tanaka, Taketoshi Maehara, Shigeki Aoki, and Tadashi Nariai
- Organizer
  ISMRM 25th Annual Meeting & Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] Correlation between brain microstructure revealed by Neurite Orientation Dispersion and Density Imaging and cerebral hemodynamics and metabolism measured with positron emission tomography in patients with moyamoya disease2017
- Author(s)
  Hara S, Hori M, Inaji M, Maehara T, Ishii K, Aoki S. Nariai T
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] 新規拡散MRI・NODDI法によるもやもや病の脳微細構造の検討2017
- Author(s)
  原祥子、成相直、堀正明、村田渉、上田亮、中澤美咲、田中洋次、青木茂樹、前原健寿
- Organizer
  第42回日本脳卒中学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] 新規拡散MRI・NODDI法によるもやもや病の脳微細構造の検討2017
- Author(s)
  原祥子、成相直、堀正明、村田渉、上田亮、中澤美咲、田中洋次、前原健寿、青木茂樹
- Organizer
  第40回日本脳神経CI学学会
- Place of Presentation
  鹿児島
- Year and Date
  2017-03-03
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] Correlation of Intravoxel Incoherent Motion and 15O-gas PET in patients with Moyamoya disease2017
- Author(s)
  Hara S, Hori M, Ueda R, Tanaka Y, Maehara T, Ishii K, Nariai T, Aoki S
- Organizer
  the 5th International Congress on Magnetic Resonance Imaging (ICMRI 2017) and 22nd Scientific Meeting of KSMRM
- Place of Presentation
  Seoul, Korea
- Year and Date
  2017-03-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] 新規拡散MRI・NODDI法によるもやもや病の脳微細構造の検討2017
- Author(s)
  原祥子、成相直、堀正明、村田渉、上田亮、中澤美咲、田中洋次、前原健寿、青木茂樹
- Organizer
  第46回日本神経放射線学会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-16K19995
[Presentation] Neurite orientation dispersion and density imaging revealed the brain microstructural ischemic damage of moyamoya disease2016
- Author(s)
  Hara S, Nariai T, Murata S, Tsuruta K, Tanaka Y, Hori M, Maehara T, Aoki S
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego, U.S.A.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19995

1. 鎌形康司 (60568153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. HORI masaaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
3. AOKI shigeki

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
4. NARIAI tadashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
5. ISHII kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. 稲次基希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HARA SHOKO 原 祥子

Hara Shoko 原 祥子

Research Projects

Research Products

Co-Researchers

GLymphatic system and blood brain barrier dysfunction evaluated by MRI in patients with moyamoya diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Brain microstructural correlates of neurocognitive dysfunction in pediatric and adult Moyamoya disease elucidated from Myelin imaging and diffusion MRIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clinical significance of diffusion MRI in patients with Moyamoya diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Increased Parenchymal Free Water May Be Decreased by Revascularization Surgery in Patients with Moyamoya Disease2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Diffusivity Along the Perivascular Space is Decreased and Related to Hypoperfusion in Adult Moyamoya disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Myelin and Axonal Damage in Normal-Appearing White Matter in Patients with Moyamoya Disease2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regression of White Matter Hyperintensity after Indirect Bypass Surgery in a Patient with Moyamoya Disease2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Unraveling Specific Brain Microstructural Damage in Moyamoya Disease Using Diffusion Magnetic Resonance Imaging and Positron Emission Tomography.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intravoxel Incoherent Motion Perfusion in Patients with Moyamoya Disease: Comparison with 15O-gas Positron Emission Tomograph2019

Author(s)

Journal Title

Data Source

[Journal Article] Microstructural Damage in Normal-Appearing Brain Parenchyma and Neurocognitive Dysfunction in Adult Moyamoya Disease2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] もやもや病の脳血流障害に伴う CNS-interstitial fluidopathyと 血行再建術後変化2023

Author(s)

Organizer

Data Source

[Presentation] Do adult patients with moyamoya disease have glymphatic system dysfunction? - evaluation using diffusion along perivascular space2023

Author(s)

Organizer

Data Source

[Presentation] 血行再建術がもやもや病の脈絡叢に与える影響2023

Author(s)

Organizer

Data Source

[Presentation] 小児もやもや病ー基本から最新知見までー2023

Author(s)

Organizer

Data Source

[Presentation] ALPS indexを用いたもやもや病患者におけるGlymphatic system評価の試み2022

Author(s)

HARA SHOKO 原祥子

Hara Shoko 原祥子

[Presentation] もやもや病の脳血流障害に伴う CNS-interstitial fluidopathyと血行再建術後変化2023