Kanesaka Manato 金坂学斗

Researcher Number	60775039
Other IDs
Affiliation (based on the past Project Information) *help	2024: 千葉大学, 大学院医学研究院, 助教 2022 – 2023: 千葉大学, 医学部附属病院, 助教 2020 – 2021: 千葉大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related
Keywords	Principal Investigator 前立腺癌 / エピゲノム / 低酸素 / 微小環境 / 低酸素環境 / 癌エピゲノム / 去勢抵抗性前立腺癌

網羅的シストローム解析に基づくAR非依存性前立腺癌の分子病態解明Principal Investigator
- Principal Investigator
  
  金坂学斗
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Chiba University
Epigenetic mechanism of castration resistance prostate cancer in response to tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  Kanesaka Manato
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Chiba University

All 2025 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Clinical significance of primary tumor progression in metastatic hormone-sensitive prostate cancer2025
- Author(s)
  Yamada Yasutaka、Sakamoto Shinichi、Tsujino Takuya、Azuma Haruhito、Ichikawa Tomohiko et al
- Journal Title
  
  Prostate International
  
  Volume: 13 Issue: 1 Pages: 60-66
- DOI
  10.1016/j.prnil.2024.11.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14606, KAKENHI-PROJECT-23K19497, KAKENHI-PROJECT-23K15757, KAKENHI-PROJECT-24K19665
[Journal Article] Association Between Residual Urine Volume and Recurrence Among Patients at High Risk of Non-Muscle-Invasive Bladder Carcinoma With Versus Without Bacillus Calmette-Gu?rin Treatment2024
- Author(s)
  Murakami Yuki、Sazuka Tomokazu、Tsukamoto Ryo、Sato Hiroaki、Ando Keisuke、Kanesaka Manato、Yamada Yasutaka、Imamura Yusuke、Sakamoto Shinichi、Ichikawa Tomohiko
- Journal Title
  
  Cureus
  
  Volume: 31 Pages: 401-402
- DOI
  10.7759/cureus.61345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09494, KAKENHI-PROJECT-23K15757
[Journal Article] Machine learning analysis for detecting late recurrence and loss to follow‐up after renal cell carcinoma surgery2024
- Author(s)
  Sato Kodai、Sazuka Tomokazu、Arai Takayuki、Sato Hiroaki、Kanesaka Manato、Ando Keisuke、Saito Shinpei、Pae Sangjon、Yamada Yasutaka、Imamura Yusuke、Sakamoto Shinichi、Ichikawa Tomohiko
- Journal Title
  
  BJUI Compass
  
  Volume: 5 Issue: 10 Pages: 1064-1070
- DOI
  10.1002/bco2.425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K02575, KAKENHI-PROJECT-22K09494, KAKENHI-PROJECT-23K15757
[Journal Article] Characterization of PSA dynamics and oncological outcomes in patients with metastatic hormone-sensitive prostate cancer treated with androgen receptor signaling inhibitors2024
- Author(s)
  Yamada Yasutaka、Sato Kodai、Sakamoto Shinichi、Tsujino Takuya、Azuma Haruhito、Ichikawa Tomohiko et al
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 30 Issue: 3 Pages: 539-550
- DOI
  10.1007/s10147-024-02676-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14606, KAKENHI-PROJECT-23K19497, KAKENHI-PROJECT-24K02575, KAKENHI-PROJECT-23K15757, KAKENHI-PROJECT-24K19665
[Journal Article] The <scp>LAT1</scp> inhibitor <scp>JPH203</scp> suppresses the growth of castration‐resistant prostate cancer through a <scp>CD24</scp>‐mediated mechanism2024
- Author(s)
  Saito S, Ando K, Sakamoto S, Xu M, Yamada Y, Rii J, Kanaoka S, Wei J, Zhao X, Pae S, Kanesaka M, Goto Y, Sazuka T, Imamura Y, Reien Y, Hamaguchi-Suzuki N, Saito S, Hirayama Y, Hashimoto H, Kanai Y, Ichikawa T, Anzai N.
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 7 Pages: 2461-2472
- DOI
  10.1111/cas.16191
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19348, KAKENHI-PROJECT-21H03065, KAKENHI-PROJECT-23K24071, KAKENHI-PROJECT-22K06840, KAKENHI-PROJECT-24K02575, KAKENHI-PROJECT-23K15757, KAKENHI-PROJECT-24K19646
[Journal Article] Chromatin activation with H3K36me2 and compartment shift in metastatic castration-resistant prostate cancer2024
- Author(s)
  Kanaoka Sanji、Okabe Atsushi、Kanesaka Manato、Rahmutulla Bahityar、Fukuyo Masaki、Seki Motoaki、Hoshii Takayuki、Sato Hiroaki、Imamura Yusuke、Sakamoto Shinichi、Ichikawa Tomohiko、Kaneda Atsushi
- Journal Title
  
  Cancer Letters
  
  Volume: 588 Pages: 216815-216815
- DOI
  10.1016/j.canlet.2024.216815
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15757, KAKENHI-PROJECT-19KK0415, KAKENHI-PROJECT-22K19553, KAKENHI-PROJECT-21K16727, KAKENHI-PROJECT-23K23859, KAKENHI-PROJECT-22K07164, KAKENHI-PROJECT-24K02575, KAKENHI-PROJECT-24K11061, KAKENHI-PROJECT-24K19646
[Journal Article] Implications of unconventional histological subtypes on magnetic resonance imaging and oncological outcomes in patients who have undergone radical prostatectomy2024
- Author(s)
  Kurokawa Koichiro、Yamada Yasutaka、Sakamoto Shinichi、Horikoshi Takuro、Sato Kodai、Nanba Sakie、Kubota Yoshihiro、Kanesaka Manato、Fujimoto Ayumi、Takeuchi Nobuyoshi、Shibata Hiroki、Sazuka Tomokazu、Imamura Yusuke、Tsuzuki Toyonori、Uno Takashi、Ichikawa Tomohiko
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 14868-14868
- DOI
  10.1038/s41598-024-65681-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K02575, KAKENHI-PROJECT-23K15757
[Journal Article] Machine-learning predicts time-series prognosis factors in metastatic prostate cancer patients treated with androgen deprivation therapy2023
- Author(s)
  Saito Shinpei、Sakamoto Shinichi、Higuchi Kosuke、Sato Kodai、Zhao Xue、Wakai Ken、Kanesaka Manato、Kamada Shuhei、Takeuchi Nobuyoshi、Sazuka Tomokazu、Imamura Yusuke、Anzai Naohiko、Ichikawa Tomohiko、Kawakami Eiryo
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 6325-6325
- DOI
  10.1038/s41598-023-32987-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03065, KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-23K15757
[Journal Article] Preoperative PI-RADS v2.1 Scoring System Improves Risk Classification in Patients Undergoing Radical Prostatectomy2023
- Author(s)
  FUKUI YUDAI、YAMADA YASUTAKA、SAKAMOTO SHINICHI、HORIKOSHI TAKURO、ZHAO XUE、SATO KODAI、NANBA SAKIE、KUBOTA YOSHIHIRO、KANESAKA MANATO、FUJIMOTO AYUMI、SHIBATA HIROKI、GOTO YUSUKE、SAZUKA TOMOKAZU、IMAMURA YUSUKE、UNO TAKASHI、ICHIKAWA TOMOHIKO
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 12 Pages: 5705-5712
- DOI
  10.21873/anticanres.16776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15757
[Journal Article] Clinical utility of the prognostic nutritional index in patients with metastatic hormone‐sensitive prostate cancer: A retrospective, multicenter, cohort study2023
- Author(s)
  Yamada Yasutaka、Sakamoto Shinichi、Sato Kodai、Saito Shinpei、Kanesaka Manato、Rii Junryo、Kurokawa Koichiro、Tachiwaki Daisuke、Fukui Yudai、Shibata Hiroki、Goto Yusuke、Sazuka Tomokazu、Imamura Yusuke、Nakatsu Hiroomi、Ichikawa Tomohiko
- Journal Title
  
  The Prostate
  
  Volume: 83 Issue: 16 Pages: 1610-1618
- DOI
  10.1002/pros.24619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15757
[Journal Article] Functional analysis of LAT3 in prostate cancer: Its downstream target and relationship with androgen receptor2021
- Author(s)
  Rii Junryo、Sakamoto Shinichi、Sugiura Masahiro、Kanesaka Manato、Fujimoto Ayumu、Yamada Yasutaka、Maimaiti Maihulan、Ando Keisuke、Wakai Ken、Xu Minhui、Imamura Yusuke、Shindo Norihisa、Hirota Toru、Kaneda Atsushi、Kanai Yoshikatsu、Ikehara Yuzuru、Anzai Naohiko、Ichikawa Tomohiko
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 9 Pages: 3871-3883
- DOI
  10.1111/cas.14991
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07677, KAKENHI-PROJECT-19K07682, KAKENHI-PROJECT-20K21625, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-18H04034, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-21H03065, KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-20K18133, KAKENHI-PROJECT-21K20742
[Journal Article] The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-22021
- Author(s)
  Maimaiti Maihulan、Sakamoto Shinichi、Sugiura Masahiro、Kanesaka Manato、Fujimoto Ayumi、Matsusaka Keisuke、Xu Minhui、Ando Keisuke、Saito Shinpei、Wakai Ken、Imamura Yusuke、Nakayama Keiichi、Kanai Yoshikatsu、Kaneda Atsushi、Ikehara Yuzuru、Ikeda Jun-Ichiro、Anzai Naohiko、Ichikawa Tomohiko
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 11478-11478
- DOI
  10.1038/s41598-021-90748-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K07682, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-20K09572, KAKENHI-PROJECT-21K06881, KAKENHI-PROJECT-20K18133, KAKENHI-PROJECT-21K20742
[Journal Article] Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer2021
- Author(s)
  Sugiura Masahiro、Sato Hiroaki、Okabe Atsushi、Fukuyo Masaki、Mano Yasunobu、Shinohara Ken-ichi、Rahmutulla Bahityar、Higuchi Kosuke、Maimaiti Maihulan、Kanesaka Manato、Imamura Yusuke、Furihata Tomomi、Sakamoto Shinichi、Komiya Akira、Anzai Naohiko、Kanai Yoshikatsu、Luo Jun、Ichikawa Tomohiko、Kaneda Atsushi
- Journal Title
  
  Translational Oncology
  
  Volume: 14 Issue: 1 Pages: 100915-100915
- DOI
  10.1016/j.tranon.2020.100915
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-20K18133, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-18K16725, KAKENHI-PROJECT-19K16765, KAKENHI-PROJECT-20K09555
[Journal Article] Revision of CHAARTED and LATITUDE criteria among Japanese de novo metastatic prostate cancer patients2021
- Author(s)
  Kanesaka Manato、Sakamoto Shinichi、Yamada Yasutaka、Rii Junryo、Maimaiti Maihulan、Sazuka Tomokazu、Imamura Yusuke、Komiya Akira、Akakura Koichiro、Ikehara Yuzuru、Nakatsu Hiroomi、Ichikawa Tomohiko
- Journal Title
  
  Prostate International
  
  Volume: 9 Issue: 4 Pages: 208-214
- DOI
  10.1016/j.prnil.2021.06.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07682, KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-20K18133
[Journal Article] Epigenetic modifications in prostate cancer2020
- Author(s)
  Sugiura Masahiro、Sato Hiroaki、Kanesaka Manato、Imamura Yusuke、Sakamoto Shinichi、Ichikawa Tomohiko、Kaneda Atsushi
- Journal Title
  
  International Journal of Urology
  
  Volume: 28 Issue: 2 Pages: 140-149
- DOI
  10.1111/iju.14406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K18133, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-20H03813
[Presentation] Cancer gene panel testing for patients with urological cancers in Chiba University Hospital2024
- Author(s)
  金坂学斗、大野泉、塚本亮、安藤敬佑、佐藤広明、佐塚智和、今村有佑、坂本信一、市川智彦
- Organizer
  第111回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-23K15757
[Presentation] Dependence on glycolysis related to alteration of FOXA1 cistrome in castration-resistant prostate cancer2023
- Author(s)
  金坂学斗、星居孝之、岡部篤史、佐藤広明、福世真樹、縄井バハテヤリラヒムトラ、金岡尚志、杉浦正洋、今村有佑、坂本信一、金田篤志、市川智彦
- Organizer
  第110回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-23K15757
[Presentation] 当院における前立腺癌患者のがん遺伝子パネル検査の実施状況2023
- Author(s)
  金坂学斗、坂本信一、佐塚智和、今村有佑、大野泉、西村基、松下一之、市川智彦
- Organizer
  第30回日本遺伝子診療学会大会
- Data Source
  KAKENHI-PROJECT-23K15757
[Presentation] 血清テストステロン値は前立腺癌に対するGnRHアンタゴニスト療法の予後を予測する2022
- Author(s)
  金坂学斗、坂本信一、鎌田修平、木下涼、竹内信善、佐塚智和、今村有佑、赤倉功一郎、市川智彦
- Organizer
  日本性機能学会第32回学術総会
- Data Source
  KAKENHI-PROJECT-20K18133
[Presentation] Cancer Gene Panel Testing for Patients with Prostate Cancer in Chiba University Hospital2022
- Author(s)
  金坂学斗、坂本信一、池原哲郎、岩井純平、田中慧樹、新納潤、柴田裕貴、竹内信善、佐塚智和、今村有佑、市川智彦
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K18133
[Presentation] Dependence on glycolysis by FOXA1-mediated epigenetic alteration in castration-resistant prostate cancer2022
- Author(s)
  金坂学斗，星居孝之，岡部篤史，佐藤広明，福世真樹，縄井バハテヤリラヒムトラ，金岡尚志，杉浦正洋，坂本信一，市川智彦，金田篤志
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K18133
[Presentation] 当院の前立腺癌患者に対するがん遺伝子パネル検査の実施状況2022
- Author(s)
  金坂学斗、坂本信一、竹内信善、佐塚智和、今村有佑、大野　泉、市川智彦
- Organizer
  第37回前立腺シンポジウム
- Data Source
  KAKENHI-PROJECT-20K18133
[Presentation] Identification of metabolic shift mediated by epigenetic alteration in castration resistant prostate cancer2021
- Author(s)
  Manato Kanesaka, Takayuki Hoshii, Atsushi Okabe, Hiroaki Sato, Sanji Kanaoka, Masahiro Sugiura, Masaki Fukuyo, Bahityar Rahmutulla Nawai, Shinichi Sakamoto, Akira Komiya, Tomohiko Ichikawa, Atsushi Kaneda
- Organizer
  The 8th Cancer Epigenomics Symposium
- Data Source
  KAKENHI-PROJECT-20K18133
[Presentation] Relationship between epigenetic and metabolic alterations in castration-resistant prostate cancer2021
- Author(s)
  Manato Kanesaka, Hiroaki Sato, Masahiro Sugiura, Takayuki Hoshii, Atsushi Okabe, Masaki Fukuyo, Bahityar Rahmutulla Nawai, Shinichi Sakamoto, Akira Komiya, Tomohiko Ichikawa, Atsushi Kaneda
- Organizer
  The 80th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20K18133
[Presentation] 去勢抵抗性獲得後のエピゲノム変化に由来する前立腺癌の代謝シフトについて2021
- Author(s)
  金坂学斗、佐藤広明、杉浦正洋、金岡尚志、星居孝之、岡部篤史、福世真樹、縄井バハテヤリラヒムトラ、今村有佑、坂本信一、小宮顕、金田篤志、市川智彦
- Organizer
  第36回前立腺シンポジウム
- Data Source
  KAKENHI-PROJECT-20K18133
[Presentation] Alterations in response to hypoxia in gaining castration resistant prostate cancer2020
- Author(s)
  Manato Kanesaka, Hiroaki Sato, Masahiro Sugiura, Takayuki Hoshii, Atsushi Okabe, Masaki Fukuyo, Shinichi Sakamoto, Akira Komiya, Tomohiko Ichikawa, Atsushi Kaneda
- Organizer
  The 79th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20K18133
[Presentation] 去勢抵抗性獲得前後の前立腺癌における低酸素応答の相違について2020
- Author(s)
  金坂学斗、佐藤広明、杉浦正洋、岡部篤史、福世真樹、今村有佑、仲村和芳、坂本信一、小宮顕、金田篤志、市川智彦
- Organizer
  第108回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-20K18133

1. SAZUKA Tomokazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. SAKAMOTO Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
3. MATSUSAKA Keisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. YAMADA YASUTAKA

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. FUKUYO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 進藤軌久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 市川智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 川上英良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 安西尚彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 辻野拓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 池原譲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kanesaka Manato 金坂 学斗

Research Projects

Research Products

Co-Researchers

網羅的シストローム解析に基づくAR非依存性前立腺癌の分子病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epigenetic mechanism of castration resistance prostate cancer in response to tumor microenvironmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Clinical significance of primary tumor progression in metastatic hormone-sensitive prostate cancer2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association Between Residual Urine Volume and Recurrence Among Patients at High Risk of Non-Muscle-Invasive Bladder Carcinoma With Versus Without Bacillus Calmette-Gu?rin Treatment2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Machine learning analysis for detecting late recurrence and loss to follow‐up after renal cell carcinoma surgery2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of PSA dynamics and oncological outcomes in patients with metastatic hormone-sensitive prostate cancer treated with androgen receptor signaling inhibitors2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The <scp>LAT1</scp> inhibitor <scp>JPH203</scp> suppresses the growth of castration‐resistant prostate cancer through a <scp>CD24</scp>‐mediated mechanism2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chromatin activation with H3K36me2 and compartment shift in metastatic castration-resistant prostate cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Implications of unconventional histological subtypes on magnetic resonance imaging and oncological outcomes in patients who have undergone radical prostatectomy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Machine-learning predicts time-series prognosis factors in metastatic prostate cancer patients treated with androgen deprivation therapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preoperative PI-RADS v2.1 Scoring System Improves Risk Classification in Patients Undergoing Radical Prostatectomy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical utility of the prognostic nutritional index in patients with metastatic hormone‐sensitive prostate cancer: A retrospective, multicenter, cohort study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional analysis of LAT3 in prostate cancer: Its downstream target and relationship with androgen receptor2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-22021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer2021

Author(s)

Journal Title

DOI

Kanesaka Manato 金坂学斗