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NGO XUANKIEN  NGO XUANKIEN

ORCIDConnect your ORCID iD *help
Researcher Number 60778190
Other IDs
Affiliation (Current) 2026: 金沢大学, ナノ生命科学研究所, 特任助教
Affiliation (based on the past Project Information) *help 2023 – 2024: 金沢大学, ナノ生命科学研究所, 特任助教
2019 – 2021: 金沢大学, ナノ生命科学研究所, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 43040:Biophysics-related
Except Principal Investigator
Basic Section 43040:Biophysics-related
Keywords
Principal Investigator
HS-AFM / MsbA / High-speed AFM / Lipid A / ABC transporter / LptB2FG / FRET / E. coli / Lipopolysaccharide (LPS) / Multidrug resistance … More / LptC / Nanodisc / Membrane Protein / High Speed AFM / ABC Transporter MsbA / Nanodiscs / Proteoliposomes / Vitamin B12 / BtuCDF / STED confocal microsopy / giant proteovesicles / proteoliposomes / lipopolysaccharide / lipid A / ABC transporters … More
Except Principal Investigator
協働的構造変化 / 記憶効果 / ヌクレオチド交換 / 協同的構造変化 / 長距離アロステリー / 協同性 / コフィリン / ミオシン / アクチン Less
  • Research Projects

    (3 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (9 People)
  •  The mechanism of sparsely bound actin binding proteins regulate the function of the entire actin filament

    • Principal Investigator
      上田 太郎
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Waseda University
  •  Structures and dynamics of ABC transporters MsbA and LptB2FG in working with LptC during transport activitiesPrincipal Investigator

    • Principal Investigator
      NGO XUANKIEN
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Kanazawa University
  •  Structural Dynamics of ABC Transporter MsbA during Functional ActivityPrincipal Investigator

    • Principal Investigator
      NGO XUANKIEN
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Kanazawa University

All 2025 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

  • [Journal Article] Developing the Computational Image Processing Method for Quantitative Analysis of Nanopore Structure Obtained from HS-AFM (AFMnanoQ)2025

    • Author(s)
      Tran Nguyen Thuyen Vinh、Ly Ngoc Quoc、Phuong Le Ngan Thi、Nguyen Hoang Duc、Ngo Kien Xuan
    • Journal Title

      BioRxiv

      Volume: 0000 Pages: 0000-0000

    • DOI

      10.1101/2025.02.26.640237

    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Journal Article] Imaging oligomers of alpha-toxin (Hla) variants using high-speed AFM and neutralizing Hla hemolytic activity with their antisera2025

    • Author(s)
      Le Ngan Thi Phuong、Ngo Kien Xuan、Nguyen Trinh Thi Ngoc、Tran Linh-Thuoc、Nguyen Hoang Duc
    • Journal Title

      Archives of Biochemistry and Biophysics

      Volume: 768 Pages: 110403-110403

    • DOI

      10.1016/j.abb.2025.110403

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27145, KAKENHI-PROJECT-23K05713
  • [Journal Article] Multiple Mechanisms to Regulate Actin Functions: “Fundamental” Versus Lineage-Specific Mechanisms and Hierarchical Relationships2025

    • Author(s)
      Uyeda Taro Q. P.、Yamazaki Yosuke、Kijima Saku T.、Noguchi Taro Q. P.、Ngo Kien Xuan
    • Journal Title

      Biomolecules

      Volume: 15 Issue: 2 Pages: 279-279

    • DOI

      10.3390/biom15020279

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K27145, KAKENHI-PROJECT-23K05713, KAKENHI-PROJECT-24K09404, KAKENHI-PROJECT-24K18120
  • [Journal Article] Atomic Conformational Dynamics and Actin-Crosslinking Function of Alpha-Actinin Revealed by SimHS-AFMfit2025

    • Author(s)
      Ngo Kien Xuan、Sumikama Takashi、Vuillemot Remi、Nguyen Han Gia、Uyeda Taro QP、Le Ngan Thi Phuong、Grudinin Sergei
    • Journal Title

      bioRxiv

      Volume: - Pages: 0000-0000

    • DOI

      10.1101/2025.04.06.647477

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K01308, KAKENHI-PROJECT-23K05713
  • [Journal Article] PQBP3/NOL7 is an intrinsically disordered protein2024

    • Author(s)
      Homma Hidenori、Ngo Kien Xuan、Yoshioka Yuki、Tanaka Hikari、Inotsume Maiko、Fujita Kyota、Ando Toshio、Okazawa Hitoshi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 736 Pages: 150453-150453

    • DOI

      10.1016/j.bbrc.2024.150453

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-22H00464, KAKENHI-PROJECT-23K27145, KAKENHI-PROJECT-23K05713
  • [Journal Article] S100A11 promotes focal adhesion disassembly via myosin II-driven contractility and Piezo1-mediated Ca2+ entry2024

    • Author(s)
      Mohammed Tareg Omer、Lin You-Rong、Akter Lucky、Weissenbruch Kai、Ngo Kien Xuan、Zhang Yanjun、Kodera Noriyuki、Bastmeyer Martin、Miyanari Yusuke、Taoka Azuma、Franz Clemens M.
    • Journal Title

      Journal of Cell Science

      Volume: 137 Issue: 2 Pages: 1-14

    • DOI

      10.1242/jcs.261492

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-23K26816, KAKENHI-PUBLICLY-22H04688, KAKENHI-PROJECT-21H04765, KAKENHI-PROJECT-22K04890, KAKENHI-PROJECT-23K05713
  • [Journal Article] Deciphering the actin structure-dependent preferential cooperative binding of cofilin2024

    • Author(s)
      Kien Xuan Ngo, Huong T Vu, Kenichi Umeda, Minh-Nhat Trinh, Noriyuki Kodera, Taro Q.P. Uyeda
    • Journal Title

      eLife

      Volume: x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Journal Article] PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradation2024

    • Author(s)
      Yoshioka Yuki、Huang Yong、Jin Xiaocen、Ngo Kien Xuan、Kumaki Tomohiro、Jin Meihua、Toyoda Saori、Takayama Sumire、Inotsume Maiko、Fujita Kyota、Homma Hidenori、Ando Toshio、Tanaka Hikari、Okazawa Hitoshi
    • Journal Title

      The EMBO Journal

      Volume: 43 Issue: 18 Pages: 3968-3999

    • DOI

      10.1038/s44318-024-00192-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-22H00464, KAKENHI-PROJECT-23K05713
  • [Journal Article] Deciphering the actin structure-dependent preferential cooperative binding of cofilin2024

    • Author(s)
      Ngo Kien Xuan、Vu Huong T、Umeda Kenichi、Trinh Minh-Nhat、Kodera Noriyuki、Uyeda Taro
    • Journal Title

      eLife

      Volume: 13 Pages: 0000-0000

    • DOI

      10.7554/elife.95257

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24H00402, KAKENHI-PROJECT-23K27145, KAKENHI-PROJECT-23K05713
  • [Journal Article] High-speed atomic force microscopy for filming protein molecules in dynamic action2023

    • Author(s)
      Ando Toshio, Fukuda Shingo, Ngo Kien Xua, Flechsig Holger
    • Journal Title

      Annual Review of Biophysics

      Volume: 53 Issue: 1 Pages: 1-1

    • DOI

      10.1146/annurev-biophys-030722-113353

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K03483, KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-23K27145, KAKENHI-PROJECT-23K05713
  • [Journal Article] Actin-binding domain of Rng2 sparsely bound on F-actin strongly inhibits actin movement on myosin II2022

    • Author(s)
      Hayakawa Yuuki、Takaine Masak、Ngo Kien Xuan、Imai Taiga、Yamada Masafumi D、Behjat Arash Badami、Umeda Kenichi、Hirose Keiko、Yurtsever Ayhan、Kodera Noriyuki、Tokuraku Kiyotaka、Numata Osamu、Fukuma Takeshi、Ando Toshio、Nakano Kentaro、Uyeda Taro QP
    • Journal Title

      Life Science Alliance

      Volume: 6 Issue: 1 Pages: e202201469-e202201469

    • DOI

      10.26508/lsa.202201469

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K04849, KAKENHI-PROJECT-22K06216, KAKENHI-PLANNED-21H05251, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-20H00345, KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-23K05713, KAKENHI-PROJECT-20K05321
  • [Journal Article] High-speed atomic force microscopy reveals a three-state elevator mechanism in the citrate transporter CitS2022

    • Author(s)
      Maity Sourav、Trinco Gianluca、Buzon Pedro、Anshari Zaid R.、Kodera Noriyuki、Ngo Kien Xuan、Ando Toshio、Slotboom Dirk J.、Roos Wouter H.
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 119 Issue: 6 Pages: 1-9

    • DOI

      10.1073/pnas.2113927119

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06581, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-22H00405
  • [Journal Article] Actin binding domain of Rng2 sparsely bound on F-actin strongly inhibits actin movement on myosin II2022

    • Author(s)
      Hayakawa Yuuki、Takaine Masak、Ngo Kien Xuan、Imai Taiga、Yamada Masafumi D.、Behjat Arash Badami、Umeda Kenichi、Hirose Keiko、Yurtsever Ayhan、Kodera Noriyuki、Tokuraku Kiyotaka、Numata Osamu、Fukuma Takeshi、Ando Toshio、Nakano Kentaro、Uyeda Taro Q.P.
    • Journal Title

      bioRxiv

      Volume: 000 Pages: 000-000

    • DOI

      10.1101/2020.04.14.041046

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06581
  • [Journal Article] Unraveling the host-selective toxic interaction of cassiicolin with lipid membranes and its cytotoxicity2022

    • Author(s)
      Ngo Kien Xuan、Nguyen Phuong Doan N.、Furusho Hirotoshi、Miyata Makoto、Shimonaka Tomomi、Chau Nguyen Ngoc Bao、Vinh Nguyen Phuong、Nghia Nguyen Anh、Mohammed Tareg Omer、Ichikawa Takehiko、Kodera Noriyuki、Konno Hiroki、Fukuma Takeshi、Quoc Nguyen Bao
    • Journal Title

      Phytopathology

      Volume: - Issue: 7 Pages: 000-000

    • DOI

      10.1094/phyto-09-21-0397-r

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06580, KAKENHI-PROJECT-19K06581, KAKENHI-PROJECT-19K06596, KAKENHI-PLANNED-21H05251, KAKENHI-PROJECT-20H00345
  • [Journal Article] Electroformation of Giant Unilamellar Vesicles and A Case Study of the Specific Host-Toxin Interaction of Lipid Membranes with Cassiicolin2021

    • Author(s)
      Kien Xuan Ngo, Conrad Weichbrodt, Nguyen Bao Quoc.
    • Journal Title

      Bio-Protocol

      Volume: bio-protocol.org/prep1167 Pages: 1-10

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06581
  • [Journal Article] GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation2021

    • Author(s)
      Ayukawa Rie、Iwata Seigo、Imai Hiroshi、Kamimura Shinji、Hayashi Masahito、Ngo Kien Xuan、Minoura Itsushi、Uchimura Seiichi、Makino Tsukasa、Shirouzu Mikako、Shigematsu Hideki、Sekimoto Ken、Gigant Benoit、Muto Etsuko
    • Journal Title

      Journal of Cell Biology

      Volume: 220 Issue: 4 Pages: 1-19

    • DOI

      10.1083/jcb.202007033

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06172, KAKENHI-PROJECT-19K06581, KAKENHI-PROJECT-19K06602
  • [Journal Article] Correlative AFM and fluorescence imaging demonstrate nanoscale membrane remodeling and ring-like and tubular structure formation by septins2021

    • Author(s)
      Vial Anthony、Taveneau Cyntia、Costa Luca、Chauvin Brieuc、Nasrallah Hussein、Godefroy Cedric、Dosset Patrice、Isambert Herve、Ngo Kien Xuan、Mangenot Stephanie、Levy Daniel、Bertin Aurelie、Milhiet Pierre-Emmanuel
    • Journal Title

      Nanoscale

      Volume: 13 Issue: 29 Pages: 12484-12493

    • DOI

      10.1039/d1nr01978c

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06581
  • [Journal Article] Unraveling the host-selective toxic interaction of cassiicolin with lipid membranes and its cytotoxicity2021

    • Author(s)
      Ngo Kien Xuan、Quoc Nguyen Bao、Nguyen Phuong Doan N.、Furusho Hirotoshi、Miyata Makoto、Shimonaka Tomomi、Chau Nguyen Ngoc Bao、Vinh Nguyen Phuong、Nghia Nguyen Anh、Mohammed Tareg Omer、Ichikawa Takehiko、Kodera Noriyuki、Konno Hiroki、Fukuma Takeshi、Ando Toshio
    • Journal Title

      bioRxiv

      Volume: 0 Pages: 0-0

    • DOI

      10.1101/2021.04.06.438527

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06581
  • [Journal Article] High Speed AFM Imaging of Structure and Dynamics of Bacterial ABC Transporter MsbA During Lipid Transport2020

    • Author(s)
      Kien Xuan Ngo
    • Journal Title

      Biophysical Journal

      Volume: 118(3) Issue: 3 Pages: 55a-55a

    • DOI

      10.1016/j.bpj.2019.11.482

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06581
  • [Presentation] High-Speed Atomic Force Microscopy for Dynamic Structural Biology2024

    • Author(s)
      Kien Xuan Ngo
    • Organizer
      The XX Rencontres du Vietnam: Vietnam Workshop on Microscopy
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Presentation] Exploring Basic Life Science with Advanced Microscopy2024

    • Author(s)
      Kien Xuan Ngo
    • Organizer
      The XX Rencontres du Vietnam: Vietnam Workshop on Microscopy
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Presentation] An Innovative Approach for Watching Dynamic Conformational Changes in Proteins at Ultrafast and Atomistic Levels2024

    • Author(s)
      Kien Xuan Ngo
    • Organizer
      Materials Informatics: Accelerating Materials Research and Design with Artificial Intelligence, ICISE, Quy Nhon, VietNam
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Presentation] A Novel Gate Operating Pathway of Lipopolysaccharide Transport by Bacterial ABC Transporter MsbA and LptC2024

    • Author(s)
      Kien Xuan Ngo
    • Organizer
      Rencontres du Vietnam: The second International Symposium of Nano Life Science: Nano Biotechnology, Biophysics, Computation (NanoBioCoM2024), ICISE, Vietnam
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Presentation] Deciphering the actin structure-dependent preferential cooperative binding of cofilin2023

    • Author(s)
      Kien Xuan Ngo, Huong T Vu, Kenichi Umeda, Noriyuki Kodera, Taro QP Uyeda, Toshio Ando
    • Organizer
      第61回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-23K27145
  • [Presentation] Elucidating the process of pore formation by alpha-hemolysin on lipid membranes using High-speed Atomic Force Microscopy2023

    • Author(s)
      Ngan Thi Phuong Le, Hanh Thi Thu Phan, Vuong Duong Le, Kien Xuan Ngo, Hoang Duc Nguyen
    • Organizer
      The First International Symposium of Nano Life Science: Nanobiotechnology, Biosensor, Computation (NanoBioCoM2023), Quy Nhon, Vietnam, Sep 17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Presentation] High-speed atomic force microscopy: development and application to explore nano world of life sciences2023

    • Author(s)
      Kien Xuan Ngo
    • Organizer
      Seminar at VinBigData, Hanoi, Vietnam, June 7th
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Presentation] Deciphering the actin structure-dependent preferential cooperative binding of cofilin2023

    • Author(s)
      Kien Xuan Ngo
    • Organizer
      The First International Symposium of Nano Life Science: Nanobiotechnology, Biosensor, Computation (NanoBioCoM2023), Quy Nhon, Vietnam, Sep 17
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Presentation] Deciphering the actin structure-dependent preferential cooperative binding of cofilin2023

    • Author(s)
      Kien Xuan Ngo, Huong T Vu, Kenichi Umeda, Noriyuki Kodera, Taro Q.P. Uyeda, Toshio Ando
    • Organizer
      The 61st Annual Meeting of the Biophysical Society of Japan, Nagoya, Japan, Nov 15
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Presentation] High-Speed Atomic Force Microscopy for Exploring Nano Life Sciences2023

    • Author(s)
      Kien Xuan Ngo
    • Organizer
      The 6th International Biology Conference, Quy Nhon, Vietnam, Sep 20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Presentation] High-speed atomic force microscopy: development and application to explore nano world of life sciences2023

    • Author(s)
      Kien Xuan Ngo
    • Organizer
      Seminar at Vin University, Hanoi, Vietnam, June 8th
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Presentation] Deciphering actin structure-dependent preferential cooperative binding of cofilin2023

    • Author(s)
      Kien Xuan Ngo, Huong T Vu, Kenichi Umeda, Noriyuki Kodera, Taro Q.P. Uyeda, Toshio Ando
    • Organizer
      The 7th NanoLSI Symposium in Berlin, Germany, Nov 2
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05713
  • [Presentation] Structural dynamics of bacterial ABC transporter MsbA during functional activity.2019

    • Author(s)
      Kien Xuan Ngo
    • Organizer
      Joint UBI-NanoLSI Workshop_Trends in Molecular Biophysics of Living Cells, Kanazawa, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K06581
  • [Presentation] The mechanisms of cooperative inhibition of actomyosin movement in vitro by the actin binding protein Rng2.2019

    • Author(s)
      Yuuki Hayakawa, Yosuke Kakuta, Kien Xuan Ngo, Noriyuki Kodera, Taro QP Uyeda
    • Organizer
      The 57th Annual Meeting of the Biophysical Society of Japan, Miyazaki, Japan
    • Data Source
      KAKENHI-PROJECT-19K06581
  • [Presentation] Actin filaments must experience and utilize different structures for regulating the binding and function of many actin binding proteins.2019

    • Author(s)
      Kien Xuan Ngo
    • Organizer
      11th Toyota Riken International Workshop Actin Filament: Beyond the Atomic Resolution Structures, Nagoya, Japan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06581
  • [Presentation] Exploring Structural Dynamics of Bacterial ABC Transporter MsbA by High Speed AFM.2019

    • Author(s)
      Kien Xuan Ngo, Holger Flechsig, Noriyuki Kodera, Toshio Ando
    • Organizer
      The 57th Annual Meeting of the Biophysical Society of Japan, Miyazaki, Japan
    • Data Source
      KAKENHI-PROJECT-19K06581
  • 1.  上田 太郎 (90356551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  成田 哲博 (30360613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  KODERA Noriyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 4.  安藤 敏夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 5.  梅田 健一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  重松 秀樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  FLECHSIG Holger
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  炭竈 享司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  市川 壮彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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