Yabana Ikuko 矢花郁子

Researcher Number	60778596
Affiliation (Current)	2025: 東北医科薬科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2024: 東北医科薬科大学, 医学部, 講師 2016 – 2019: 東北医科薬科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Kidney internal medicine Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Kidney internal medicine
Keywords	Principal Investigator 慢性腎臓病 / 腎線維化 / 細胞内蛋白輸送 / V-ATPase / 酸性オルガネラ / 細胞内タンパク質輸送 / 線維化 / 腎臓 Except Principal Investigator ゲノム編集 / ラット … More / バソプレシン２型受容体 / 先天性腎性尿崩症 / 線維化 / TGF-β / V-ATPase / 腎臓生理学 / 心不全 / 腎間質線維化 / 腎間質圧 / 腎循環 / 腎うっ血 Less

AVPR2遺伝子改変ラットを用いた先天性腎性尿崩症の病態解析および治療法の探索
- Principal Investigator
  
  鎌田綾佳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Effect of V-ATPase inhibition in renal fibrosisPrincipal Investigator
- Principal Investigator
  
  Yabana Ikuko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tohoku Medical and Pharmaceutical University
Physiological and molecular mechanisms underlying renal congestion in congestive heart failure
- Principal Investigator
  
  MORI Takefumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tohoku Medical and Pharmaceutical University

All 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Acidic organelles mediate TGF-β1-induced cellular fibrosis via (pro)renin receptor and vacuolar ATPase trafficking in human peritoneal mesothelial cells.2018
- Author(s)
  1: Oba-Yabana I, Mori T, Takahashi C, Hirose T, Ohsaki Y, Kinugasa S, Muroya Y, Sato E, Nguyen G, Piedagnel R, Ronco PM, Totsune K, Ito S
- Journal Title
  
  Scientific Reports
  
  Volume: ８ Issue: 1 Pages: 2648-2648
- DOI
  10.1038/s41598-018-20940-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16092, KAKENHI-PROJECT-15H04834, KAKENHI-PROJECT-16H05312, KAKENHI-PROJECT-15K18694
[Journal Article] Urinary angiotensinogen excretion level is associated with elevated blood pressure in the normotensive general population.2018
- Author(s)
  Sato E, Wang AY, Satoh M, Nishikiori Y, Oba-Yabana I, Yoshida M, Sato H, Ito S, Hida W, Mori T
- Journal Title
  
  Am J Hypertens
  
  Volume: - Issue: 6 Pages: 742-749
- DOI
  10.1093/ajh/hpy020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04834, KAKENHI-PROJECT-16H05312, KAKENHI-PROJECT-16K09599
[Journal Article] Hydrochlorothiazide ameliorates polyuria caused by tolvaptan treatment of polycystic kidney disease in PCK rats2018
- Author(s)
  Wang Anyi、Hirose Takuo、Ohsaki Yusuke、Takahashi Chika、Sato Emiko、Oba-Yabana Ikuko、Kinugasa Satoshi、Muroya Yoshikazu、Ito Sadayoshi、Mori Takefumi
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 23 Issue: 4 Pages: 455-464
- DOI
  10.1007/s10157-018-1669-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05312
[Journal Article] Diuretic Usage for Protection against End-Organ Damage in Liver Cirrhosis and Heart Failure.2016
- Author(s)
  Mori T, Osaki Y, Oba-Yabana I, Ito S.
- Journal Title
  
  Hepatol Res.
  
  Volume: 印刷中 Issue: 1 Pages: 11-22
- DOI
  10.1111/hepr.12700
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18694, KAKENHI-PROJECT-15H04834, KAKENHI-PROJECT-25670405, KAKENHI-PROJECT-26670424, KAKENHI-PROJECT-25293193, KAKENHI-PROJECT-16H05312
[Presentation] 腎うっ血における腎循環とバゾプレシン2型受容体の役割の検討.2020
- Author(s)
  森建文, 廣瀬卓男, 大崎雄介, 髙橋知香, 矢花郁子.
- Organizer
  第30回バゾプレシン研究会
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] 腎集合管細胞に対する筋由来生理活性物質アイリシンの効果の検討.2019
- Author(s)
  廣瀬卓男, 髙橋知香, 矢花郁子, 加藤季子, 関敬之, 中村はな, 衣笠哲史, 谷淳一, 森建文.
- Organizer
  第23回日本心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] Low-vacuum scanning electron microscopy analysis for formalin-fixed paraffin-embedded rat kidney sections.2019
- Author(s)
  Moriyama S, Takeuchi W, Kaburaki T, Shimada K, Hirose T, Kinugasa S, Matsuki T, Oba-Yabana I, Muroya Y, Mori T.
- Organizer
  World Congress of Nephrology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] Exon 4-encoded domain of (pro)renin receptor impairs several V-ATPase-mediated functions2019
- Author(s)
  Hirose T, Cabrera-Socorro A, Matsuki T, Takahashi C, Oba-Yabana I, Kinugasa S, Muroya Y, Tani J, Nguyen G, Groszer M, Ito S, Mori T
- Organizer
  International Symposium for Aldosterone and Related Substances in Hypertension 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] ラット腎臓光学顕微鏡用組織標本の低真空走査電子顕微鏡での観察2019
- Author(s)
  廣瀬卓男, 衣笠哲史, 髙橋知香, 矢花郁子, 中村はな, 室谷嘉一, 谷淳一, 森建文
- Organizer
  第64回日本透析医学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] エクソン4欠失(プロ)レニン受容体のV-ATPase機能に与える影響2019
- Author(s)
  廣瀬卓男, 松木琢磨, 髙橋知香, 矢花郁子, 中村はな, 衣笠哲史, 室谷嘉一, 谷淳一, 森建文
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] ラット腎うっ血モデルにおける(プロ)レニン受容体の発現2019
- Author(s)
  松木琢磨, 廣瀬卓男, 島田佐登志, 髙橋知香, 矢花郁子, 中村はな, 衣笠哲史, 室谷嘉一, 谷淳一, 伊藤貞嘉, 森建文
- Organizer
  第11回(プロ)レニン受容体フォーラム
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] Exon 4-encoded domain of (pro)renin receptor impairs several V-ATPase-mediated functions.2019
- Author(s)
  Hirose T, Cabrera-Socorro A, Matsuki T, Takahashi C, Oba-Yabana I, Kinugasa S, Muroya Y, Tani J, Nguyen G, Groszer M, Ito S, Mori T.
- Organizer
  ISARSH2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] Low-vacuum scanning electron microscopy analysis for formalin-fixed paraffin-embedded rat kidney sections2019
- Author(s)
  Moriyama S, Takeuchi W, Kaburaki T, Shimada K, Hirose T, Kinugasa S, Matsuki T, Oba-Yabana I, Muroya Y, Mori T
- Organizer
  World Congress of Nephrology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] 光学顕微鏡用腎組織標本の低真空走査電子顕微鏡を用いた観察.2019
- Author(s)
  廣瀬卓男, 髙橋知香, 松木琢磨, 中山晋吾, 衣笠哲史, 矢花郁子, 加藤季子, 関敬之, 中村はな, 谷淳一, 森建文.
- Organizer
  第48回宮城県腎不全研究会
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] 腎うっ血における(プロ)レニン受容体の発現2019
- Author(s)
  廣瀬卓男, 島田佐登志, 松木琢磨, 髙橋知香, 矢花郁子, 中村はな, 衣笠哲史, 室谷嘉一, 谷淳一, 森建文
- Organizer
  第92回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] ポドサイト障害に対するV-ATPaseの評価2018
- Author(s)
  松木琢磨, 森建文, 高橋知香, 矢花郁子, 大崎雄介, 廣瀬卓男, 熊谷直憲, 伊藤貞嘉
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] 腹膜中皮細胞における（プロ）レニン受容体の役割の検討2018
- Author(s)
  廣瀬卓男, 矢花郁子, 髙橋知香, 衣笠哲史, 室谷嘉一, 伊藤貞嘉, 森建文
- Organizer
  第63回日本透析医学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] PCKラットにおけるトルバプタンにより誘導される水利尿作用へのサイアザイド系利尿薬の効果2018
- Author(s)
  Wang Anyi, 大崎雄介, 廣瀬卓男, 高橋知香, 矢花郁子, 衣笠哲史, 室谷嘉一, 伊藤貞嘉, 森建文
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] 腹膜透析におけるV-ATPaseと(pro)renin受容体の役割2018
- Author(s)
  森　建文、矢花郁子、廣瀬卓男、高橋知香、大崎雄介、佐藤　恵美子、伊藤貞嘉
- Organizer
  第10回(プロ)レニン受容体フォーラム
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] 腹膜中皮細胞における（プロ）レニン受容体の役割の検討2018
- Author(s)
  廣瀬卓男　矢花郁子　高橋知香　衣笠哲史　室谷嘉一　伊藤貞嘉　森建文
- Organizer
  日本透析医学会
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] ポドサイト障害に対するVATPaseの評価2018
- Author(s)
  松木琢磨　森建文　高橋知香　矢花郁子　大崎雄介　廣瀬卓男　熊谷直憲　伊藤貞嘉
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] 低真空走査電子顕微鏡によるラット腎臓光学顕微鏡用組織標本の検討2018
- Author(s)
  廣瀬卓男, 衣笠哲史, 島田佐登志, 高橋知香, 矢花郁子, 大崎雄介, 室谷嘉一, 伊藤貞嘉, 森建文
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] 酸性オルガネラによる蛋白輸送は腹膜透析におけるグルコース分解産物(GDPs)誘導性腹膜線維化に関与する2017
- Author(s)
  矢花郁子、大崎雄介、高橋知香、伊藤貞嘉、森　建文
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] 培養ポドサイト線維化機序に対するV-ATPaseの評価2017
- Author(s)
  松木琢磨、森　建文、髙橋知香、矢花郁子、大崎雄介、熊谷直憲、伊藤貞嘉
- Organizer
  第60回日本腎臓学会学術総会
- Place of Presentation
  仙台国際会議場(宮城県・仙台市)
- Year and Date
  2017-05-26
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] 細胞内蛋白輸送による腹膜線維化機序2017
- Author(s)
  森　建文、矢花郁子
- Organizer
  第23回日本腹膜透析医学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] 腎線維化における集合管酸性オルガネラの役割2017
- Author(s)
  森　建文、高橋知香、矢花郁子、大崎雄介、衣笠哲史、伊藤貞嘉
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] 酸性オルガネラによる蛋白輸送は腹膜透析におけるグルコース分解産物(GDPs)誘導性腹膜線維化に関与する2017
- Author(s)
  矢花郁子、大崎雄介、高橋知香、伊藤貞嘉、森　建文
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] 腎線維化における集合管酸性オルガネラの役割2017
- Author(s)
  森　建文、高橋知香、矢花郁子、大崎雄介、衣笠哲史、伊藤貞嘉
- Organizer
  第60回日本腎臓学会学術総会
- Place of Presentation
  仙台国際会議場 (宮城県・仙台市)
- Year and Date
  2017-05-26
- Data Source
  KAKENHI-PROJECT-16H05312
[Presentation] 培養ポドサイト線維化機序に対するV-ATPaseの評価2017
- Author(s)
  松木琢磨、森　建文、高橋知香、矢花郁子、大崎雄介、熊谷直憲、伊藤貞嘉
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K16092
[Presentation] 培養ポドサイト線維化機序に対するV-ATPaseの評価2017
- Author(s)
  松木琢磨、森　建文、高橋知香、矢花郁子、大崎雄介、熊谷直憲、伊藤貞嘉
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05312

1. MORI Takefumi (40375001)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
2. 佐藤恵美子 (20466543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 伊藤貞嘉 (40271613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
4. 大崎雄介 (40509212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. 鎌田綾佳 (00954132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 廣瀬卓男 (20599302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHIMADA Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. TAKAHASHI Chika

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results

Yabana Ikuko 矢花 郁子

Research Projects

Research Products

Co-Researchers

AVPR2遺伝子改変ラットを用いた先天性腎性尿崩症の病態解析および治療法の探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of V-ATPase inhibition in renal fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Physiological and molecular mechanisms underlying renal congestion in congestive heart failure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Acidic organelles mediate TGF-β1-induced cellular fibrosis via (pro)renin receptor and vacuolar ATPase trafficking in human peritoneal mesothelial cells.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Urinary angiotensinogen excretion level is associated with elevated blood pressure in the normotensive general population.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hydrochlorothiazide ameliorates polyuria caused by tolvaptan treatment of polycystic kidney disease in PCK rats2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diuretic Usage for Protection against End-Organ Damage in Liver Cirrhosis and Heart Failure.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] 腎うっ血における腎循環とバゾプレシン2型受容体の役割の検討.2020

Author(s)

Organizer

Data Source

[Presentation] 腎集合管細胞に対する筋由来生理活性物質アイリシンの効果の検討.2019

Author(s)

Organizer

Data Source

[Presentation] Low-vacuum scanning electron microscopy analysis for formalin-fixed paraffin-embedded rat kidney sections.2019

Author(s)

Organizer

Data Source

[Presentation] Exon 4-encoded domain of (pro)renin receptor impairs several V-ATPase-mediated functions2019

Author(s)

Organizer

Data Source

[Presentation] ラット腎臓光学顕微鏡用組織標本の低真空走査電子顕微鏡での観察2019

Author(s)

Organizer

Data Source

[Presentation] エクソン4欠失(プロ)レニン受容体のV-ATPase機能に与える影響2019

Author(s)

Organizer

Data Source

[Presentation] ラット腎うっ血モデルにおける(プロ)レニン受容体の発現2019

Author(s)

Organizer

Data Source

[Presentation] Exon 4-encoded domain of (pro)renin receptor impairs several V-ATPase-mediated functions.2019

Author(s)

Organizer

Data Source

[Presentation] Low-vacuum scanning electron microscopy analysis for formalin-fixed paraffin-embedded rat kidney sections2019

Author(s)

Organizer

Data Source

[Presentation] 光学顕微鏡用腎組織標本の低真空走査電子顕微鏡を用いた観察.2019

Author(s)

Yabana Ikuko 矢花郁子