Shimada Keisuke 嶋田圭祐

… Alternative Names

Keisuke Shimada 嶋田圭祐

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Researcher Number	60779601
Other IDs	https://orcid.org/0000-0003-3739-7163
Affiliation (Current)	2026: 酪農学園大学, 獣医学群, 准教授
Affiliation (based on the past Project Information) *help	2026: 酪農学園大学, 獣医学群, 准教授 2018 – 2024: 大阪大学, 微生物病研究所, 助教 2017: 大阪大学, 微生物病研究所, 特任研究員(常勤)
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related / Basic Section 44040:Morphology and anatomical structure-related / Basic Section 48010:Anatomy-related / Integrative animal science
Keywords	Principal Investigator 精子ミトコンドリア / 精子形成 / 雄性不妊 / ミトコンドリア鞘 / 液-液相分離 / nuage / ゲノム編集 / ミトコンドリア鞘形成

精子形成制御に関わる新規分子群の同定と分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  嶋田圭祐
- Project Period (FY)
  2026 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Rakuno Gakuen University
Study of the formation mechanism of spherical mitochondria during spermatogenesis.Principal Investigator
- Principal Investigator
  
  嶋田圭祐
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  Osaka University
Analysis of mitochondrial sheath formation mechanism using KO micePrincipal Investigator
- Principal Investigator
  
  Shimada Keisuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Osaka University
Revealing the mechanism of mitochondrial localization in the sperm midpiecePrincipal Investigator
- Principal Investigator
  
  Keisuke Shimada
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Integrative animal science
- Research Institution
  Osaka University

All 2025 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] TEX38 localizes ZDHHC19 to the plasma membrane and regulates sperm head morphogenesis in mice2025
- Author(s)
  Kaneda Yuki、Lu Yonggang、Sun Jiang、Shimada Keisuke、Emori Chihiro、Noda Taichi、Koyano Takayuki、Matsuyama Makoto、Miyata Haruhiko、Ikawa Masahito
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 122 Issue: 10 Pages: 1-10
- DOI
  10.1073/pnas.2417943122
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-23K24473, KAKENHI-PROJECT-24K02033, KAKENHI-PROJECT-23K05831, KAKENHI-PROJECT-24K09314, KAKENHI-PROJECT-23K18328, KAKENHI-PROJECT-23KJ1523, KAKENHI-PROJECT-23K20043
[Journal Article] Disruption of testis-enriched cytochrome c oxidase subunit COX6B2 but not COX8C leads to subfertility2024
- Author(s)
  Shimada Keisuke、Lu Yonggang、Ikawa Masahito
- Journal Title
  
  Exp. Anim.
  
  Volume: 73 Issue: 1 Pages: 1-10
- DOI
  10.1538/expanim.23-0055
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15103, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-23K05831
[Journal Article] FBXO24 ensures male fertility by preventing abnormal accumulation of membraneless granules in sperm flagella2024
- Author(s)
  Kaneda Yuki、Miyata Haruhiko、Xu Zoulan、Shimada Keisuke、Kamoshita Maki、Nakagawa Tatsuya、Emori Chihiro、Ikawa Masahito
- Journal Title
  
  eLife
  
  Volume: - Pages: 1-36
- DOI
  10.7554/elife.92794.1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05831
[Journal Article] MYCBPAP is a central apparatus protein required for centrosome?nuclear envelope docking and sperm tail biogenesis in mice2024
- Author(s)
  Wang Haoting、Kobayashi Hiroko、Shimada Keisuke、Oura Seiya、Oyama Yuki、Kitakaze Hiroaki、Noda Taichi、Yabuta Norikazu、Miyata Haruhiko、Ikawa Masahito
- Journal Title
  
  Journal of Cell Science
  
  Volume: 137 Issue: 16 Pages: 1-18
- DOI
  10.1242/jcs.261962
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-23K24473, KAKENHI-PROJECT-21K07122, KAKENHI-PROJECT-23K05831, KAKENHI-PROJECT-23K18328
[Journal Article] Gene-deficient mouse model established by CRISPR/Cas9 system reveals 15 reproductive organ-enriched genes dispensable for male fertility2024
- Author(s)
  Nguyen Tuyen Thi Thanh、Tokuhiro Keizo、Shimada Keisuke、Wang Haoting、Mashiko Daisuke、Tonai Shingo、Kiyozumi Daiji、Ikawa Masahito
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 12 Pages: 1411162-1411162
- DOI
  10.3389/fcell.2024.1411162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02487, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-23K05831
[Journal Article] Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male mice2024
- Author(s)
  Suzuki Akira、Yabuta Norikazu、Shimada Keisuke、Mashiko Daisuke、Tokuhiro Keizo、Oyama Yuki、Miyata Haruhiko、Garcia Thomas X.、Matzuk Martin M.、Ikawa Masahito
- Journal Title
  
  Journal of Reproductive Immunology
  
  Volume: 163 Pages: 104252-104252
- DOI
  10.1016/j.jri.2024.104252
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-21K07122, KAKENHI-PROJECT-23K05831, KAKENHI-PROJECT-23K20043
[Journal Article] Development of functional spermatozoa in mammalian spermiogenesis2024
- Author(s)
  Miyata Haruhiko、Shimada Keisuke、Kaneda Yuki、Ikawa Masahito
- Journal Title
  
  Development
  
  Volume: 151 Issue: 14 Pages: 1-16
- DOI
  10.1242/dev.202838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-23K24473, KAKENHI-PROJECT-23K05831, KAKENHI-PROJECT-23K18328, KAKENHI-PROJECT-23KJ1523
[Journal Article] Loss of CCDC188 causes male infertility with defects in the sperm head?neck connection in mice2024
- Author(s)
  Qiu Yumiao、Shimada Keisuke、Yamamoto Kaito、Ikawa Masahito
- Journal Title
  
  Biology of Reproduction
  
  Volume: 112 Issue: 1 Pages: 169-178
- DOI
  10.1093/biolre/ioae137
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-23K05831, KAKENHI-PROJECT-23K20043
[Journal Article] CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility2023
- Author(s)
  Shimada Keisuke、Ikawa Masahito
- Journal Title
  
  Development
  
  Volume: 150 Issue: 21 Pages: 1-11
- DOI
  10.1242/dev.201724
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05831
[Journal Article] Evaluation of the efficacy of creatine chemical exchange saturation transfer imaging in assessing testicular maturity2023
- Author(s)
  Kuribayashi Sohei、Fukuhara Shinichiro、Tsujimura Go、Imanaka Takahiro、Okada Koichi、Ueda Norichika、Takezawa Kentaro、Kiuchi Hiroshi、Saito Shigeyoshi、Takahashi Yusuke、Kioka Hidetaka、Oura Seiya、Shimada Keisuke、Ikawa Masahito、Nonomura Norio
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 22 Issue: 1 Pages: 1-9
- DOI
  10.1002/rmb2.12507
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08155, KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-21K15776, KAKENHI-PROJECT-23K15117, KAKENHI-PROJECT-19K08172
[Journal Article] Testis‐specific proteins, TSNAXIP1 and 1700010I14RIK, are important for sperm motility and male fertility in mice2023
- Author(s)
  Kaneda Yuki、Miyata Haruhiko、Shimada Keisuke、Oura Seiya、Ikawa Masahito
- Journal Title
  
  Andrology
  
  Volume: - Issue: 5 Pages: 1-9
- DOI
  10.1111/andr.13378
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19569, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-20K16107, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-23K24473
[Journal Article] TSKS localizes to nuage in spermatids and regulates cytoplasmic elimination during spermiation2023
- Author(s)
  Shimada Keisuke、Park Soojin、Oura Seiya、Noda Taichi、Morohoshi Akane、Matzuk Martin M.、Ikawa Masahito
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 11 Pages: 1-10
- DOI
  10.1073/pnas.2221762120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-20H03172, KAKENHI-PROJECT-20K16107, KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05750
[Journal Article] Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.2022
- Author(s)
  Mise S#, Matsumoto A#*, Shimada K, Hosaka T, Takahashi M, Ichihara K, Shimizu H, Shiraishi C, Saito D, Suyama M, Yasuda T, Ide T, Izumi Y, Bamba T, Kimura-Someya T, Shirouzu M, Miyata H, Ikawa M, Nakayama KI*.
- Journal Title
  
  Nat. Commun.
  
  Volume: 13(1) Issue: 1 Pages: 1071-1071
- DOI
  10.1038/s41467-022-28677-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05167, KAKENHI-PROJECT-20K21397, KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-17H06304, KAKENHI-PROJECT-20J11940, KAKENHI-PROJECT-18K06157, KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-21K17856, KAKENHI-PROJECT-21H02751, KAKENHI-PROJECT-20K15101, KAKENHI-PLANNED-20H05928
[Journal Article] CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice2022
- Author(s)
  Oyama Yuki、Miyata Haruhiko、Shimada Keisuke、Fujihara Yoshitaka、Tokuhiro Keizo、Garcia ThomasX、Matzuk MartinM、Ikawa Masahito
- Journal Title
  
  Asian Journal of Andrology
  
  Volume: in press Issue: 3 Pages: 0-0
- DOI
  10.4103/aja.aja_63_21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-21H04753, KAKENHI-PROJECT-21H02397, KAKENHI-PROJECT-20K06476, KAKENHI-PROJECT-21K19198, KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-20KK0155
[Journal Article] TULP2 deletion mice exhibit abnormal outer dense fiber structure and male infertility2022
- Author(s)
  Oyama Yuki、Miyata Haruhiko、Shimada Keisuke、Larasati Tamara、Fujihara Yoshitaka、Ikawa Masahito
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 21 Issue: 1 Pages: 1-8
- DOI
  10.1002/rmb2.12467
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19569, KAKENHI-PROJECT-20KK0155, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-21H02397, KAKENHI-PROJECT-21K19198, KAKENHI-PROJECT-20K16107, KAKENHI-PLANNED-19H05750
[Journal Article] IRGC1, a testis-enriched immunity related GTPase, is important for fibrous sheath integrity and sperm motility in mice2022
- Author(s)
  Kaneda Yuki、Miyata Haruhiko、Shimada Keisuke、Oyama Yuki、Iida-Norita Rie、Ikawa Masahito
- Journal Title
  
  Developmental Biology
  
  Volume: 488 Pages: 104-113
- DOI
  10.1016/j.ydbio.2022.05.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19569, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-20K16107, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-23K24473
[Journal Article] ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility2021
- Author(s)
  Shimada Keisuke、Park Soojin、Miyata Haruhiko、Yu Zhifeng、Morohoshi Akane、Oura Seiya、Matzuk Martin M.、Ikawa Masahito
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 6 Pages: 1-12
- DOI
  10.1073/pnas.2018355118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16107, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-19J21619, KAKENHI-PROJECT-20J10363
[Journal Article] LRRC23 is a conserved component of the radial spoke that is necessary for sperm motility and male fertility in mice2021
- Author(s)
  Zhang Xin、Sun Jiang、Lu Yonggang、Zhang Jintao、Shimada Keisuke、Noda Taichi、Zhao Shuqin、Koyano Takayuki、Matsuyama Makoto、Zhou Shushu、Wu Jiayan、Ikawa Masahito、Liu Mingxi
- Journal Title
  
  Journal of Cell Science
  
  Volume: 134 Issue: 20 Pages: 1-14
- DOI
  10.1242/jcs.259381
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16735, KAKENHI-PROJECT-20H03172, KAKENHI-PROJECT-20K16107
[Journal Article] SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice2021
- Author(s)
  Miyata Haruhiko、Oura Seiya、Morohoshi Akane、Shimada Keisuke、Mashiko Daisuke、Oyama Yuki、Kaneda Yuki、Matsumura Takafumi、Abbasi Ferheen、Ikawa Masahito
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 35 Pages: 1-9
- DOI
  10.1073/pnas.2106673118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-21H04753, KAKENHI-PROJECT-19J21619, KAKENHI-PROJECT-21K19569, KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-22KJ3051
[Journal Article] FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice2021
- Author(s)
  Castaneda Julio M.、Shimada Keisuke、Satouh Yuhkoh、Yu Zhifeng、Devlin Darius J.、Ikawa Masahito、Matzuk Martin M.
- Journal Title
  
  Journal of Cell Science
  
  Volume: 134 Issue: 21 Pages: 1-11
- DOI
  10.1242/jcs.259206
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06686, KAKENHI-PROJECT-20K15804, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-20K16107, KAKENHI-PLANNED-19H05711, KAKENHI-PROJECT-20H00466
[Journal Article] Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis2021
- Author(s)
  Monsivais Diana、Nagashima Takashi、Prunskaite-Hyyrylainen Renata、Nozawa Kaori、Shimada Keisuke、Tang Suni、Hamor Clark、Agno Julio E.、Chen Fengju、Masand Ramya P.、Young Steven L.、Creighton Chad J.、DeMayo Francesco J.、Ikawa Masahito、Lee Se-Jin、Matzuk Martin M.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1-17
- DOI
  10.1038/s41467-021-23571-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16107
[Journal Article] CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity2020
- Author(s)
  Park Soojin、Shimada Keisuke、Fujihara Yoshitaka、Xu Zoulan、Shimada Kentaro、Larasati Tamara、Pratiwi Putri、Matzuk Ryan M、Devlin Darius J、Yu Zhifeng、Garcia Thomas X、Matzuk Martin M、Ikawa Masahito
- Journal Title
  
  Biology of Reproduction
  
  Volume: 103 Issue: 2 Pages: 195-204
- DOI
  10.1093/biolre/ioaa084
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-20KK0155, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-20J10363
[Journal Article] PHF7 Modulates BRDT Stability and Histone-to-Protamine Exchange during Spermiogenesis2020
- Author(s)
  Kim Chang Rok、Noda Taichi、Kim Hyunkyung、Kim Gibeom、Park Seongwan、Na Yongwoo、Oura Seiya、Shimada Keisuke、Bang Injin、Ahn Jun-Yeong、Kim Yong Ryoul、Oh Se Kyu、Choi Hee-Jung、Kim Jong-Seo、Jung Inkyung、Lee Ho、Okada Yuki、Ikawa Masahito、Baek Sung Hee
- Journal Title
  
  Cell Reports
  
  Volume: 32 Issue: 4 Pages: 107950-107950
- DOI
  10.1016/j.celrep.2020.107950
- NAID
  120006957463
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16107, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-19J21619
[Journal Article] Welfare Impact of Carbon Dioxide Euthanasia on Laboratory Mice and Rats: A Systematic Review2020
- Author(s)
  Turner Patricia V.、Hickman Debra L.、van Luijk Judith、Ritskes-Hoitinga Merel、Sargeant Jan M.、Kurosawa T. Miki、Agui Takashi、Baumans Vera、Choi Woo Sung、Choi Yang-Kyu、Flecknell Paul A.、Lee Byeong H.、Otaegui Pedro J.、Pritchett-Corning Kathleen R.、Shimada Keisuke
- Journal Title
  
  Frontiers in Veterinary Science
  
  Volume: 7 Pages: 1-18
- DOI
  10.3389/fvets.2020.00411
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16107
[Journal Article] Nexin-Dynein regulatory complex component DRC7 but not FBXL13 is required for sperm flagellum formation and male fertility in mice2020
- Author(s)
  Morohoshi Akane、Miyata Haruhiko、Shimada Keisuke、Nozawa Kaori、Matsumura Takafumi、Yanase Ryuji、Shiba Kogiku、Inaba Kazuo、Ikawa Masahito
- Journal Title
  
  PLOS Genetics
  
  Volume: 16 Issue: 1 Pages: 1-21
- DOI
  10.1371/journal.pgen.1008585
- NAID
  120007159540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06592, KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H01440, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-17K17852, KAKENHI-PROJECT-16H06280
[Journal Article] Tmprss12 is required for sperm motility and uterotubal junction migration in mice2020
- Author(s)
  §Larasati T., §Noda T., Fujihara Y., Shimada K., Tobita T., Yu Z., Matzuk M.M., Ikawa M.
- Journal Title
  
  Biology of Reproduction
  
  Volume: - Issue: 2 Pages: 254-263
- DOI
  10.1093/biolre/ioaa060
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14612, KAKENHI-PROJECT-16KK0180, KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-20KK0155, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-20H03172
[Journal Article] Testis‐enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa2020
- Author(s)
  Miyata Haruhiko、Shimada Keisuke、Morohoshi Akane、Oura Seiya、Matsumura Takafumi、Xu Zoulan、Oyama Yuki、Ikawa Masahito
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 4 Pages: 5389-5400
- DOI
  10.1096/fj.201902755r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17K17852, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987
[Journal Article] Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility2020
- Author(s)
  Liu Chunyu、Miyata Haruhiko、Gao Yang、Sha Yanwei、Tang Shuyan、Xu Zoulan、、、Wu Huan、Dulioust Emmanuel、Tian Shixiong、Shimada Keisuke、Cong Jiangshan、、、Aminata、Zhang Feng、Ikawa Masahito
- Journal Title
  
  The American Journal of Human Genetics
  
  Volume: 107 Issue: 2 Pages: 330-341
- DOI
  10.1016/j.ajhg.2020.06.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16107, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H04987, KAKENHI-ORGANIZER-19H05749
[Journal Article] Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis2019
- Author(s)
  Shimada K, Kato H, Miyata H, Ikawa M.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 65 Issue: 2 Pages: 155-162
- DOI
  10.1262/jrd.2018-136
- NAID
  130007630929
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-17K17852
[Journal Article] CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†2019
- Author(s)
  Yonggang Lu, Oura Seiya, Matsumura Takafumi, et al.
- Journal Title
  
  Biology of Reproduction
  
  Volume: 101 Issue: 2 Pages: 501-511
- DOI
  10.1093/biolre/ioz103
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16735, KAKENHI-PUBLICLY-18H04885, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-19J00865, KAKENHI-PROJECT-17K17852, KAKENHI-PROJECT-18K14612, KAKENHI-PROJECT-18K14715, KAKENHI-PROJECT-16KK0180
[Journal Article] Chimeric analysis with newly established EGFP/DsRed2-tagged ES cells identify HYDIN as essential for spermiogenesis in mice2019
- Author(s)
  Oura Seiya、Miyata Haruhiko、Noda Taichi、Shimada Keisuke、Matsumura Takafumi、Morohoshi Akane、Isotani Ayako、Ikawa Masahito
- Journal Title
  
  Exp. Anim.
  
  Volume: 68 Issue: 1 Pages: 25-34
- DOI
  10.1538/expanim.18-0071
- NAID
  130007604401
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14612, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-17J09669, KAKENHI-PROJECT-17K17852, KAKENHI-PUBLICLY-18H04885, KAKENHI-PROJECT-16K07091
[Journal Article] RSPH6A is required for sperm flagellum formation and male fertility in mice2018
- Author(s)
  Abbasi Ferheen、Miyata Haruhiko、Shimada Keisuke、Morohoshi Akane、Nozawa Kaori、Matsumura Takafumi、Xu Zoulan、Pratiwi Putri、Ikawa Masahito
- Journal Title
  
  Journal of Cell Science
  
  Volume: 131 Pages: 1-11
- DOI
  10.1242/jcs.221648
- NAID
  120006957445
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17852, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-17J09669
[Presentation] Molecular Mechanism Analysis Involved in Mitochondrial Sheath Formation2025
- Author(s)
  Keisuke Shimada
- Organizer
  ASA & ICA 2025
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05831
[Presentation] CCDC183は精子形成過程において軸糸微小管のコンパートメント化に必須である2024
- Author(s)
  嶋田圭祐、伊川正人
- Organizer
  日本アンドロロジー学会第43回学術大会
- Data Source
  KAKENHI-PROJECT-23K05831
[Presentation] CCDC183は精子形成過程における鞭毛周囲の細胞質陥入および軸糸微小管のコンパートメント化に必須である2024
- Author(s)
  嶋田圭祐、伊川正人
- Organizer
  第71回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-23K05831
[Presentation] CCDC183 is Essential for Axonemal Compartmentalization during Spermiogenesis2024
- Author(s)
  Keisuke Shimada and Masahito Ikawa
- Organizer
  SSR 57th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05831
[Presentation] TSKS-derived nuages regulate the transportation of cytoplasmic contents during spermiation2023
- Author(s)
  Shimada Keisuke; Park Soojin; Oura Seiya; Noda Taichi; Morohoshi Akane; Martin M. Matzuk; Ikawa Masahito
- Organizer
  EMBO Workshop European testis workshop 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05831
[Presentation] 遺伝子改変マウスを用いた精子形成に関する分子メカニズム解析2023
- Author(s)
  嶋田圭祐
- Organizer
  実験動物札幌セミナー2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K05831
[Presentation] ARMC12はTBC1D21と協働してミトコンドリア鞘形成を可能にする2022
- Author(s)
  嶋田圭祐, Park Soojin，宮田治彦，Zhifeng Yu，諸星茜，大浦聖矢，Martin M. Matzuk，伊川正人
- Organizer
  第69回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-20K16107
[Presentation] ARMC12は精子形成期においてミトコンドリア外膜上で接着因子として働くことでミトコンドリア鞘形成を可能にする2021
- Author(s)
  嶋田圭祐, Soojin Park, 宮田治彦, Zhifeng Yu, 諸星茜, 大浦聖矢, Martin M. Matzuk, 伊川正人
- Organizer
  日本アンドロロジー学会第40回学術大会
- Data Source
  KAKENHI-PROJECT-20K16107
[Presentation] ARMC12は精子形成期におけるミトコンドリア鞘形成に必須である2020
- Author(s)
  嶋田圭祐, Soojin Park, 宮田治彦, Zhifeng Yu, 諸星茜, 大浦聖矢, Martin M. Matzuk, 伊川正人
- Organizer
  第１６３回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16107
[Presentation] Molecular mechanism of mitochondrial sheath formation revealed through gene-edited mice2019
- Author(s)
  嶋田圭祐
- Organizer
  第14回研究所ネットワーク国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17852
[Presentation] SMDR1は精子形成期においてミトコンドリア間を繋ぎ止めて精子中片部にミトコンドリア鞘を形成するのに必須のタンパク質である2019
- Author(s)
  嶋田圭祐
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K17852
[Presentation] Glycerol kinase 2 is important for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath2019
- Author(s)
  Keisuke Shimada
- Organizer
  SSR 52nd Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17852
[Presentation] SMDR1は精子ミトコンドリアの鞭毛への巻き付きに必須である2018
- Author(s)
  嶋田圭祐
- Organizer
  第33回日本生殖免疫学会
- Data Source
  KAKENHI-PROJECT-17K17852
[Presentation] Smdr1 is required for sperm mitochondrial alignment during spermatogenesis2018
- Author(s)
  Keisuke Shimada
- Organizer
  The 1st International YoungMito 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17852
[Presentation] Smdr1 is required for sperm mitochondrial alignment during spermatogenesis2018
- Author(s)
  嶋田圭祐
- Organizer
  The 1st International Mitochondria Meeting for Young Scientists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17852
[Presentation] SMDR1は精子形成期における精子ミトコンドリアの鞭毛への巻き付きに関わることでミトコンドリア鞘の形成に必須となるタンパク質である2018
- Author(s)
  嶋田圭祐
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K17852

1. SHIBA Kogiku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. KIYOZUMI Daiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. MIYATA Haruhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
4. SATOUH Yuhkoh

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 和泉自泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 木岡秀隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 伊川正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
8. Lu Yonggang

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 野田大地

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimada Keisuke 嶋田 圭祐

Keisuke Shimada 嶋田 圭祐

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精子形成制御に関わる新規分子群の同定と分子メカニズムの解明Principal Investigator

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Study of the formation mechanism of spherical mitochondria during spermatogenesis.Principal Investigator

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Analysis of mitochondrial sheath formation mechanism using KO micePrincipal Investigator

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Revealing the mechanism of mitochondrial localization in the sperm midpiecePrincipal Investigator

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[Journal Article] TEX38 localizes ZDHHC19 to the plasma membrane and regulates sperm head morphogenesis in mice2025

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[Journal Article] Disruption of testis-enriched cytochrome c oxidase subunit COX6B2 but not COX8C leads to subfertility2024

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[Journal Article] FBXO24 ensures male fertility by preventing abnormal accumulation of membraneless granules in sperm flagella2024

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[Journal Article] MYCBPAP is a central apparatus protein required for centrosome?nuclear envelope docking and sperm tail biogenesis in mice2024

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[Journal Article] Gene-deficient mouse model established by CRISPR/Cas9 system reveals 15 reproductive organ-enriched genes dispensable for male fertility2024

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[Journal Article] Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male mice2024

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[Journal Article] Development of functional spermatozoa in mammalian spermiogenesis2024

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[Journal Article] Loss of CCDC188 causes male infertility with defects in the sperm head?neck connection in mice2024

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[Journal Article] CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility2023

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[Journal Article] Evaluation of the efficacy of creatine chemical exchange saturation transfer imaging in assessing testicular maturity2023

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Shimada Keisuke 嶋田圭祐

Keisuke Shimada 嶋田圭祐