Yamazaki Hiroki 山崎広貴

Researcher Number	60784337
Other IDs	https://orcid.org/0000-0001-7788-392X
Affiliation (Current)	2026: 帝京大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 帝京大学, 医学部, 講師 2021 – 2022: 慶應義塾大学, 医学部(信濃町), 助教 2017 – 2020: 東京大学, 医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Metabolomics Except Principal Investigator Basic Section 48040:Medical biochemistry-related / Basic Section 59020:Sports sciences-related
Keywords	Principal Investigator 臓器連関 / 加齢 / 骨格筋 / グルココルチコイド / サルコペニア / エネルギー代謝 / 健康長寿 / マイオカイン / 代謝 / EPA … More / 脂質異常症 / 代謝異常 / 内分泌 / 多臓器連関 / グルココルチコイド受容体 / 糖尿病 / 肥満 / 性差 / 性ホルモン結合グロブリン(SHBG) / 糖・脂質代謝 / 慢性炎症 / 脂質代謝 / 抗炎症 / 抗肥満 … More Except Principal Investigator 癌 / ケミカルバイオロジー / 肝機能 / 炎症 / 肥満 / 天然物 / 性同一性障害 / 性染色体 / 性ホルモン / ホルモン療法 / トランスジェンダー Less

トランスジェンダーを対象とした健康の維持増進に資する運動プログラム開発の基盤構築
- Principal Investigator
  
  須永美歌子
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Nippon Sport Science University
天然物グリチルリチンの作用を指標とした膜受容体PGRMC1の肝機能・炎症制御の解明
- Principal Investigator
  
  加部泰明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kochi University
骨格筋グルココルチコイド作用が個体の加齢性変化に与える影響の解明Principal Investigator
- Principal Investigator
  
  山崎広貴
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Teikyo University
Analysis of the significance of sex in muscle metabolism and elucidation of sex differences in systemic metabolismPrincipal Investigator
- Principal Investigator
  
  Yamazaki Hiroki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Keio University
  The University of Tokyo
Establishment of strategies for anti-obesity and improvement of glucose and lipid metabolism through clarifying physiological significance of SHBGPrincipal Investigator
- Principal Investigator
  
  Yamazaki Hiroki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] フレイル・ロコモのグランドデザイン2024
- Author(s)
  山崎広貴, 塚本和久
- Total Pages
  458
- Publisher
  日本医事新報社
- Data Source
  KAKENHI-PROJECT-24K11686
[Journal Article] Trk-fused gene plays a critical role in diet-induced adipose tissue expansion and is also involved in thyroid hormone action2024
- Author(s)
  Yamamotoya Takeshi、Ohata Yukino、Akasaka Yasuyuki、Hasei Shun、Inoue Masa-Ki、Nakatsu Yusuke、Kanna Machi、Yamazaki Hiroki、Kushiyama Akifumi、Fujishiro Midori、Ono Hiraku、Sakoda Hideyuki、Yamada Tetsuya、Ishihara Hisamitsu、Asano Tomoichiro
- Journal Title
  
  PNAS Nexus
  
  Volume: 3 Issue: 4 Pages: 150-150
- DOI
  10.1093/pnasnexus/pgae150
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24385, KAKENHI-PROJECT-21K08580, KAKENHI-PROJECT-23K27650, KAKENHI-PROJECT-22K08655, KAKENHI-PROJECT-24K11686, KAKENHI-PROJECT-24K11698, KAKENHI-PROJECT-24K11706
[Journal Article] The crucial role of muscle glucocorticoid signaling in accelerating obesity and glucose intolerance via hyperinsulinemia2023
- Author(s)
  Yamazaki Hiroki、Uehara Masaaki、Yoshikawa Noritada、Kuribara-Souta Akiko、Yamamoto Motohisa、Hirakawa Yasuko、Kabe Yasuaki、Suematsu Makoto、Tanaka Hirotoshi
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 8
- DOI
  10.1172/jci.insight.162382
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08881, KAKENHI-PROJECT-20K17528, KAKENHI-PROJECT-21K06845
[Journal Article] Effects of acute aerobic exercise on arterial stiffness in transgender men2023
- Author(s)
  Yamada Mizuki、Gam Hyunjun、Ikegami Nodoka、Nishikawa Yuriko、Ishikawa Akira、Funaki Akiko、Matsuda Tomoka、Kamemoto Kayoko、Hashimoto Yuto、Okamoto Takanobu、Yamazaki Hiroki、Tanaka Hirotoshi、Sakamaki-Sunaga Mikako
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 14 Pages: 01-07
- DOI
  10.3389/fphys.2023.1294284
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K16715, KAKENHI-PROJECT-22K21228, KAKENHI-PROJECT-23K27977
[Journal Article] The differential diagnosis of IgG4-related disease based on machine learning.2022
- Author(s)
  Motohisa Yamamoto, Hiroki Yamazaki, Hirotoshi Tanaka, et al.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 24 Issue: 1 Pages: 71-71
- DOI
  10.1186/s13075-022-02752-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0017, KAKENHI-PROJECT-19K08973, KAKENHI-PROJECT-20K08881, KAKENHI-PROJECT-19K17904, KAKENHI-PROJECT-20K17528, KAKENHI-PROJECT-21K09658, KAKENHI-PROJECT-20K08770
[Journal Article] Glycyrrhizin Derivatives Suppress Cancer Chemoresistance by Inhibiting Progesterone Receptor Membrane Component 12021
- Author(s)
  Yasuaki Kabe, Ikko Koike, Tatsuya Yamamoto, Miwa Hirai, Ayaka Kanai, Ryogo Furuhata, Hitoshi Tsugawa, Erisa Harada, Kenji Sugase, Kazue Hanadate, Nobuji Yoshikawa, Hiroaki Hayashi, Masanori Noda, Susumu Uchiyama, Hiroki Yamazaki, Hirotoshi Tanaka, Takuya Kobayashi, Hiroshi Handa, Makoto Suematsu.
- Journal Title
  
  Cancers (Basel)
  
  Volume: 13 Issue: 13 Pages: 3265-3265
- DOI
  10.3390/cancers13133265
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0017, KAKENHI-PROJECT-19K07068, KAKENHI-PROJECT-20K08881, KAKENHI-PROJECT-21K06845, KAKENHI-PROJECT-21K19360, KAKENHI-PROJECT-20K17528
[Journal Article] Aseptic Meningitis-retention Syndrome Associated with Tocilizumab in a Patient with Idiopathic Multicentric Castleman Disease2021
- Author(s)
  Akira Arakawa, Masaki Iizuka, Shunichi Matsuda, Erika Matsubara, Hiroki Yamazaki, Noritada Yoshikawa, Hirotoshi Tanaka, Toshihiro Yoshizawa.
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 24 Pages: 3995-3998
- DOI
  10.2169/internalmedicine.6938-20
- NAID
  130008129490
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-12-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0017, KAKENHI-PROJECT-20K08881, KAKENHI-PROJECT-20K17528
[Journal Article] Eicosapentaenoic acid changes muscle transcriptome and intervenes in aging-related fiber type transition in male mice2021
- Author(s)
  Yamazaki Hiroki、Nishimura Mayu、Uehara Masaaki、Kuribara-Souta Akiko、Yamamoto Motohisa、Yoshikawa Noritada、Morohashi Ken-Ichirou、Tanaka Hirotoshi
- Journal Title
  
  American Journal of Physiology-Endocrinology and Metabolism
  
  Volume: 320 Issue: 2 Pages: E346-E358
- DOI
  10.1152/ajpendo.00184.2020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0017, KAKENHI-PROJECT-19K08973, KAKENHI-PROJECT-20K17528, KAKENHI-PLANNED-17H06427, KAKENHI-PROJECT-20H03436
[Journal Article] The Influence of Glucocorticoid Receptor on Sex Differences of Gene Expression Profile in Skeletal Muscle2021
- Author(s)
  Yoshikawa Noritada、Oda Aya、Yamazaki Hiroki、Yamamoto Motohisa、Kuribara-Souta Akiko、Uehara Masaaki、Tanaka Hirotoshi
- Journal Title
  
  Endocrine Research
  
  Volume: - Issue: 3 Pages: 1-15
- DOI
  10.1080/07435800.2021.1884874
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0017, KAKENHI-PROJECT-20K08881, KAKENHI-PROJECT-20K17528, KAKENHI-PROJECT-19K08973
[Journal Article] Correlation among body composition and metabolic regulation in a male mouse model of Cushing’s syndrome2020
- Author(s)
  Uehara M, Yamazaki H, Yoshikawa N, Kuribara-Souta A, Tanaka H
- Journal Title
  
  Endocr J
  
  Volume: 67 Issue: 1 Pages: 21-30
- DOI
  10.1507/endocrj.EJ19-0205
- NAID
  130007790982
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0017, KAKENHI-PROJECT-19K08973, KAKENHI-PROJECT-16H05330, KAKENHI-PROJECT-17K16158, KAKENHI-PROJECT-20K08881
[Journal Article] Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages2018
- Author(s)
  Yamazaki Hiroki、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Yamamotoya Takeshi、Nakatsu Yusuke、Kikuchi Takako、Kaneko Sunao、Tanaka Hirotoshi、Asano Tomoichiro
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2018 Pages: 1-12
- DOI
  10.1155/2018/3062319
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KT0017, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-17K16158, KAKENHI-PROJECT-16H05330, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791
[Presentation] The role of muscle glucocorticoid receptor signaling in accelerating obesity, glucose intolerance, and aging-related metabolic changes2024
- Author(s)
  Yamazaki H, Uehara M, Kuribara-Souta A, Yamamoto M, Kabe Y, Suematsu M, Tsukamoto K, Tanaka H.
- Organizer
  Joint Conference of the 22nd Annual Meeting of Asian Oceanian Myology Center and the 10th Annual Meeting of Japan Muscle Society (AOMC-JMS 2024)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K11686
[Presentation] グルココルチコイド投与時の全身性代謝変化における骨格筋の役割2024
- Author(s)
  山崎広貴
- Organizer
  筋・骨・リウマチ 3学会合同若手研究会
- Data Source
  KAKENHI-PROJECT-24K11686
[Presentation] 有酸素性トレーニングがトランスジェンダー男性の血中脂質に与える影響2024
- Author(s)
  山田満月, 林七虹, 松田知華, 亀本佳世子, 尾崎隼朗, 山崎広貴, 田中廣壽, 須永美歌子
- Organizer
  第78回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-24K11686
[Presentation] Genetic and Biochemical Analysis of Four Japanese Severe Hypertriglyceridemia2024
- Author(s)
  Suzuki T, Kurano M, Yamazaki H, Uno-Eder K, Edo N, Unoi K, Morita K, Ishikawa T, Tsukamoto K
- Organizer
  20th International Symposium on Atherosclerosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K11686
[Presentation] トランスジェンダー男性における性別適合手術の有無が一過性有酸素運動時の糖質・脂質酸化量に与える影響2023
- Author(s)
  山田満月、市川季穂、北島彩音、中山真羽、石川明良、平松樹亜、宮口愛子、鰐淵めぐみ、林七虹、亀本佳世子、山崎広貴、田中廣壽、須永美歌子
- Organizer
  第36回日本トレーニング科学大会
- Data Source
  KAKENHI-PROJECT-23K27977
[Presentation] Effects of acute aerobic exercise on lipid profiles, carbohydrate and lipid oxidation in transgender men2023
- Author(s)
  Mizuki Yamada, Nodoka Ikegami, Yuriko Nishikawa, Akira Ishikawa, Akiko Funaki, Kiho Ichikawa, Ayane Kitajima, Simba Nakayama, Hirotoshi Tanaka, Hiroki Yamazaki, Mikako Sakamaki-Sunaga
- Organizer
  2023 American College of Sports Medicine Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27977
[Presentation] グルココルチコイドとサルコペニア2022
- Author(s)
  田中廣壽、山崎広貴
- Organizer
  第95回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17528
[Presentation] Effects of acute aerobic exercise on the lipid profiles in transgender men2022
- Author(s)
  Mizuki Yamada, Nodoka Ikegami, Hyunjun Gam, Yuriko Nishikawa, Akira Ishikawa, Akiko Funaki, Kayoko Kamemoto, Tomoka Matsuda, Hazuki Ogata, Hirotoshi Tanaka, Hiroki Yamazaki, Mikako Sakamaki-Sunaga
- Organizer
  American College of Sports Medicine 69th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17528
[Presentation] 一過性有酸素運動がFTMの動脈スティフネスに与える影響2021
- Author(s)
  山田満月、池上和、甘賢俊、西川百合子、石川明良、舟喜晶子、亀本佳世子、松田知華、緒方はづき、田中廣壽、山崎広貴、須永美歌子
- Organizer
  第76回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-20K17528
[Presentation] 肥満の病態における骨格筋グルココルチコイド受容体シグナルの役割2021
- Author(s)
  山崎広貴、上原昌晃、栗原明子、山本元久、平川泰子、加部泰明、末松誠、田中廣壽
- Organizer
  第７回日本筋学学術集会
- Data Source
  KAKENHI-PROJECT-20K17528
[Presentation] 機械学習に基づくIgG4関連疾患の診断支援の試み2021
- Author(s)
  山本元久、上原昌晃、山崎広貴、吉川賢忠、水島伊知郎、庄田宏文、吉藤元、川野充弘、高橋裕樹、藤尾圭志、田中廣壽
- Organizer
  第65回日本リウマチ学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17528
[Presentation] ob/obマウスの代謝異常における骨格筋グルココルチコイド受容体の意義の解析2020
- Author(s)
  山崎広貴,栗原明子,上原昌晃,西村茉優,山本元久,吉川賢忠,田中廣壽
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K17528
[Presentation] 肥満に伴う代謝異常と骨格筋トランスクリプトームとの関連の解析2019
- Author(s)
  山崎広貴、栗原明子、吉川賢忠、上原昌晃、西村茉優、山本元久、田中廣壽
- Organizer
  日本筋学会第5回学術集会
- Data Source
  KAKENHI-PROJECT-17K16158
[Presentation] 骨格筋におけるステロイド作用の解明から生体システムの統合的理解へ2019
- Author(s)
  山崎広貴、吉川賢忠、田中廣壽
- Organizer
  第74回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-17K16158
[Presentation] Inhibitory effect of sex hormone-binding globulin on lipid storage of adipocytes and on inflammation of both adipocytes and macrophages2017
- Author(s)
  Hiroki Yamazaki, Akifumi Kushiyama, Tomoichiro Asano, Toshiki Eri, Noriaki Shimizu, Noritada Yoshikawa, Hirotoshi Tanaka.
- Organizer
  12th International Symposium of the Institute Network
- Data Source
  KAKENHI-PROJECT-17K16158

1. 須永美歌子 (70534064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 関根紀子 (10393175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 福典之 (40392526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 加部泰明 (20397037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 菱木貴子 (10338022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 田中廣壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
7. 山田哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 松田知華

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamazaki Hiroki 山崎 広貴

Research Projects

Research Products

Co-Researchers

トランスジェンダーを対象とした健康の維持増進に資する運動プログラム開発の基盤構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

天然物グリチルリチンの作用を指標とした膜受容体PGRMC1の肝機能・炎症制御の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

骨格筋グルココルチコイド作用が個体の加齢性変化に与える影響の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the significance of sex in muscle metabolism and elucidation of sex differences in systemic metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of strategies for anti-obesity and improvement of glucose and lipid metabolism through clarifying physiological significance of SHBGPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] フレイル・ロコモのグランドデザイン2024

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Trk-fused gene plays a critical role in diet-induced adipose tissue expansion and is also involved in thyroid hormone action2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The crucial role of muscle glucocorticoid signaling in accelerating obesity and glucose intolerance via hyperinsulinemia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of acute aerobic exercise on arterial stiffness in transgender men2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The differential diagnosis of IgG4-related disease based on machine learning.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycyrrhizin Derivatives Suppress Cancer Chemoresistance by Inhibiting Progesterone Receptor Membrane Component 12021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aseptic Meningitis-retention Syndrome Associated with Tocilizumab in a Patient with Idiopathic Multicentric Castleman Disease2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Eicosapentaenoic acid changes muscle transcriptome and intervenes in aging-related fiber type transition in male mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Influence of Glucocorticoid Receptor on Sex Differences of Gene Expression Profile in Skeletal Muscle2021

Author(s)

Yamazaki Hiroki 山崎広貴

[Presentation] 骨格筋におけるステロイド作用の解明から生体システムの統合的理解へ2019