tanabe aki 田部亜季

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Tanabe Aki 田部亜季

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Researcher Number	60786367
Affiliation (Current)	2026: 国立健康危機管理研究機構, 国立感染症研究所エイズ研究センター, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2024: 国立感染症研究所, エイズ研究センター, 研究員 2019 – 2021: 東京大学, 大学院工学系研究科(工学部), 特任助教 2018: 東京大学, 大学院工学系研究科(工学部), 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / 0403:Biomedical engineering and related fields Except Principal Investigator Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 62010:Life, health and medical informatics-related
Keywords	Principal Investigator 成人T細胞白血病リンパ腫 / 抗体薬物複合体 / 抗体-薬物複合体 / 抗体工学 / 成人T細胞白血病 / 抗体 / HTLV-1 / ADC / ATL / 抗体エンジニアリング … More / 血液悪性腫瘍 / 自己免疫疾患 / 蛋白質間相互作用解析 / Drug Delivery / チオストレオプトン / 成人T細胞性白血病/リンパ腫 / CADM1 / 成人T細胞白血病/リンパ腫 / ドラッグデリバリー / 成人T細胞白血病リンパ腫(ATLL) / ファージディスプレイ … More Except Principal Investigator ウイルスタンパク質機能 / 疫学研究 / 疫学調査 / 細胞外微小環境 / ウイルスタンパク質 / HTLV-1 a/c / リモート診療 / オーストラリア先住民 / HTLV-1ｃ / HTLV-1c / 日本 / HTLV-1a / 気管支拡張症 / 関連疾患病態比較 / ウイルス病原性比較 / HTLV-1関連肺疾患(HAPD) / HU / HAM / ATL / HTLV-1感染症レジストリ / HTLV-1感染疫学調査 / HTLV-1抗体検査 / アボリジニ居住区 / オーストラリア / HTLV-1 type-c / HTLV-1 type-a / HTLV-1関連疾患 / 凝集性 / 熱安定性 / タンパク質工学 / シミュレーション / 蛋白質工学 / Supercharging / 単ドメイン抗体 / 分子デザイン / 機能計測 / 物性計測 / ペプチド / 抗体 / 抗体工学 / 分子設計 / 安定性 / 親和性成熟 / 機械学習 / 分子シミュレーション / ペプチド設計 / 抗体設計 Less

Development of novel therapeutics targeting Adult T-cell lukemia Lymphoma.Principal Investigator
- Principal Investigator
  
  Tanabe Aki
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Institute of Infectious Diseases
Japan-Australia joint study for epidemiological survey of HTLV-1 a/c subtypes and elucidation of their unique pathogenic mechanims
- Principal Investigator
  
  Nakano Kazumi
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  National Institute of Infectious Diseases
  The University of Tokyo
Development of novel antibody-drug conjugate for refractory hematological malignancy and autoimmune diseasePrincipal Investigator
- Principal Investigator
  
  Tanabe Aki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Institute of Infectious Diseases
  The University of Tokyo
Molecular design of real proteins in virtual space
- Principal Investigator
  
  Kuroda Daisuke
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  National Institute of Infectious Diseases
  The University of Tokyo
Thiostrepton Antibody-Drug Conjugate Targeting CADM1 for Adult T-Cell Leukemia/Lymphoma TherapyPrincipal Investigator
- Principal Investigator
  
  Tanabe Aki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0403:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo

All 2025 2024 2023 2022 2021 2020 2019

All Journal Article Presentation Book Patent

[Book] 抗体薬物複合体(ADC)の設計・合成と最新動向2024
- Author(s)
  田部亜季, 高橋良明, 渡邉俊樹, 津本浩平, 中野和民
- Total Pages
  188
- Publisher
  シーエムシー出版
- ISBN
  9784781318189
- Data Source
  KAKENHI-PROJECT-22K15598
[Journal Article] Analytical Method for Experimental Validation of Computer-Designed Antibody2022
- Author(s)
  Tanabe Aki、Tsumoto Kouhei
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2552 Pages: 409-433
- DOI
  10.1007/978-1-0716-2609-2_23
- ISBN
  9781071626085, 9781071626092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-22K15598
[Journal Article] Thrombophlebitis Migrans As the Prodrome of Adult T-Cell Leukemia-Lymphoma2022
- Author(s)
  Matsuda-Hirose Haruna、Nashimoto Yuko、Tanabe Aki、Ogata Masao、Iwao Masao、Mizukami Kazuhiro、Nishida Haruto、Hatano Yutaka
- Journal Title
  
  Annals of Dermatology
  
  Volume: 34 Issue: 4 Pages: 312-312
- DOI
  10.5021/ad.20.184
- Data Source
  KAKENHI-PROJECT-22K15598
[Journal Article] Elucidation of the mechanism of host NMD suppression by HTLV-1 Rex: Dissection of Rex to identify the NMD inhibitory domain2022
- Author(s)
  Nakano, K., Karasawa N., Hashizume M., Tanaka, Y, Ohsugi, T., Uchimaru. K. and Watanabe, T.
- Journal Title
  
  Viruses
  
  Volume: 14 Issue: 2 Pages: 344-344
- DOI
  10.3390/v14020344
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06036, KAKENHI-PROJECT-19K07573, KAKENHI-PROJECT-20KK0181
[Journal Article] Tuning Rex rules HTLV-1 pathogenesis2022
- Author(s)
  Kazumi Nakano and Toshiki Watanabe
- Journal Title
  
  Frontiers Immunology
  
  Volume: 13 Pages: 959962-959962
- DOI
  10.3389/fimmu.2022.959962
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0181
[Journal Article] Exploring New Functional Aspects of HTLV-1 RNA-Binding Protein Rex: How Does Rex Control Viral Replication?2022
- Author(s)
  Kazumi Nakano(corresponding author), Koichi Yokoyama, Shuichi Shin, Koki Uchida, Kazuki Tsuji, Marie Tanaka, Kaoru Uchimaru, and Toshiki Watanabe
- Journal Title
  
  Viruses
  
  Volume: 14 Issue: 2 Pages: 407-407
- DOI
  10.3390/v14020407
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07573, KAKENHI-PROJECT-20KK0181
[Journal Article] Antibody recognition of complement Factor H reveals a flexible loop involved in Atypical Hemolytic Uremic Syndrome pathogenesis2022
- Author(s)
  Yokoo Takanori、Tanabe Aki、Yoshida Yoko、Caaveiro Jose M.M.、Nakakido Makoto、Ikeda Yoichiro、Fujimura Yoshihiro、Matsumoto Masanori、Entzminger Kevin、Maruyama Toshiaki、Okumura C.J.、Nangaku Masaomi、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: - Issue: 6 Pages: 101962-101962
- DOI
  10.1016/j.jbc.2022.101962
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-21K08272, KAKENHI-PLANNED-21H05090, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20H03228, KAKENHI-PROJECT-20K16377
[Journal Article] Extracellular matrix-inspired hydrogel of hyaluronan and gelatin crosslinked via a Link module with a transglutaminase reactive sequence2022
- Author(s)
  Okawa Masashi、Tanabe Aki、Ohta Seiichi、Nagatoishi Satoru、Tsumoto Kouhei、Ito Taichi
- Journal Title
  
  Communications Materials
  
  Volume: 3 Issue: 1 Pages: 1-11
- DOI
  10.1038/s43246-022-00309-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15598, KAKENHI-PROJECT-20H02530, KAKENHI-PLANNED-21H05092, KAKENHI-PROJECT-21J12834
[Journal Article] Correction: Antibody recognition of complement factor H reveals a flexible loop involved in atypical hemolytic uremic syndrome pathogenesis2022
- Author(s)
  Yokoo Takanori、Tanabe Aki、Yoshida Yoko、Caaveiro Jose M.M.、Nakakido Makoto、Ikeda Yoichiro、Fujimura Yoshihiro、Matsumoto Masaneori、Entzminger Kevin、Maruyama Toshiaki、Okumura C.J.、Nangaku Masaomi、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 8 Pages: 102262-102262
- DOI
  10.1016/j.jbc.2022.102262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15598, KAKENHI-PROJECT-20H02531
[Journal Article] Development of biparatopic bispecific antibody possessing tetravalent scFv-Fc capable of binding to ROBO1 expressed in hepatocellular carcinoma cells2021
- Author(s)
  Watanabe Yuji、Tanabe Aki、Hamakubo Takao、Nagatoishi Satoru、Tsumoto Kouhei
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 170 Issue: 2 Pages: 307-315
- DOI
  10.1093/jb/mvab049
- NAID
  40022722450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-20K16377
[Journal Article] Overexpression of aberrant Wnt5a and its effect on acquisition of malignant phenotypes in adult T-cell leukemia/lymphoma (ATL) cells.2021
- Author(s)
  Nakano K., Chihara Y., Kobayashi S., Iwanaga M., Utsunomiya A., Watanabe T., and Uchimaru K.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 4114-4114
- DOI
  10.1038/s41598-021-83613-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07573, KAKENHI-PROJECT-20KK0181, KAKENHI-PROJECT-16H06277
[Journal Article] Anion solvation enhanced by positive supercharging mutations preserves thermal stability of an antibody in a wide pH range2021
- Author(s)
  Kasahara Keisuke、Kuroda Daisuke、Tanabe Aki、Kawade Raiji、Nagatoishi Satoru、Tsumoto Kouhei
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 563 Pages: 54-59
- DOI
  10.1016/j.bbrc.2021.05.053
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-19H04202, KAKENHI-PROJECT-20K16377
[Journal Article] Structure-based design and discovery of novel anti-tissue factor antibodies with cooperative double-point mutations, using interaction analysis2020
- Author(s)
  Chiba Shuntaro、Tanabe Aki、Nakakido Makoto、Okuno Yasushi、Tsumoto Kouhei、Ohta Masateru
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 17590-17590
- DOI
  10.1038/s41598-020-74545-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20K16377
[Journal Article] A Peptoid with Ectended Shape in Water2019
- Author(s)
  Morimoto J, Fukuda Y, Kuroda D, Watanabe T, Yoshida F, Asada M, Nakamura T, Senoo A, Nagatoishi S, Tsumoto K, *Sando S
- Journal Title
  
  J Am Chem Soc.
  
  Volume: 141 Issue: 37 Pages: 14612-14623
- DOI
  10.1021/jacs.9b04371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-19H04202
[Patent] 抗CADM1抗体2022
- Inventor(s)
  田部亜季、高橋良明、中野和民、渡邉俊樹、津本浩平
- Industrial Property Rights Holder
  田部亜季、高橋良明、中野和民、渡邉俊樹、津本浩平
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-22K15598
[Patent] 抗CADM1抗体2021
- Inventor(s)
  中野和民、高橋良明、田部亜季、渡邉俊樹、津本浩平
- Industrial Property Rights Holder
  中野和民、高橋良明、田部亜季、渡邉俊樹、津本浩平
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-080133
- Filing Date
  2021
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-20KK0181
[Patent] 抗CADM1抗体2021
- Inventor(s)
  中野和民、高橋良明、田部亜季、津本浩平、渡邉俊樹
- Industrial Property Rights Holder
  東京大学、琉球大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-080133
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K16377
[Presentation] HTLV-1 testing and epidemiological studies in Japan2025
- Author(s)
  Toshiki Watanabe
- Organizer
  Japan-Australia HTLV-1 Research Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0181
[Presentation] HTLV-1/ATL therapy using anti-CADM1 antibodies2025
- Author(s)
  Aki Tanabe
- Organizer
  Japan-Australia HTLV-1 Research Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0181
[Presentation] 成人T細胞白血病/リンパ腫(ATL)を標的とする抗CADM1抗体薬物複合体の開発2024
- Author(s)
  田部亜季, 高橋良明, 由井杏奈, 中木戸誠, 那須智博, 内丸薫, 立川愛, 俣野哲朗, 水上拓郎, 渡邉俊樹, 津本浩平, 中野和民
- Organizer
  第86回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] CADM1 を標的とした抗体医薬の可能性2024
- Author(s)
  中野和民、田部亜季、高橋良明、由井杏奈、中木戸誠、那須智博、内丸薫、立川愛、俣野哲朗、水上拓郎、渡邉俊樹、津本浩平
- Organizer
  第10回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] NanoLuc レポーターシステムを利用した新たなキラーアッセイ法の検討2024
- Author(s)
  高橋良明、田部亜季、宮城拓也、渡邉俊樹、津本浩平、中野和民
- Organizer
  第10回日本HTLV-1学会学術集会, 2024年11月8-10日, 一橋講堂, 東京
- Invited
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] Development of an Antibody-Drug Conjugate Targeting CADM1 in Adult T-Cell Leukemia/Lymphoma2024
- Author(s)
  Aki Tanabe, Yoshiaki Takahashi, Anna Yui, Makoto Nakakido, Tomohiro Nasu, Mami Uemura, Kenta Tezuka, Kaoru Uchimaru, Atae Utsunomiya, Tetsuro Matano, Takuo Mizukami, Toshiki Watanabe, Kouhei Tsumoto, Kazumi Nakano
- Organizer
  American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] Development of an antibody-drug conjugate(ADC)targeting CADM1 in adult T-cell leukemia/lymphoma cells2024
- Author(s)
  Aki Tanabe, Yoshiaki Takahashi, Anna Yui, Makoto Nakakido, Tomohiro Nasu, Kaoru Uchimaru, Hiroshi Ishii, Ai Kawana-Tachikawa, Tetsuro Matano, Toshiki Watanabe, Kouhei Tsumoto, Kazumi Nakano
- Organizer
  HTLV Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] Development of antibody-based therapeutics targeting to Adult T-cell leukemia/Lymphoma2024
- Author(s)
  Aki Tanabe, Yoshiaki Takahashi, Anna Yui, Makoto Nakakido, Tomohiro Nasu、Kaoru Uchimaru, Ai Kawana-Tachikawa, Tetsuro Matano, Takuo Mizukami, Toshiki Watanabe, Kouhei Tsumoto, Kazumi Nakano
- Organizer
  The 3rd France-Japan Symposium on HIV/AIDS & Infectious Disease Basic and Translational research
- Invited
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] HTLV-1 type-aとtype-cのウイルス特性と病原性の違いに関する研究：ウイルス学的比較解析の試み2023
- Author(s)
  中野　和民、田部　亜季、佐藤　知雄、鴨居　功樹、宇都宮　與、Lloyd Einsiedel、渡邉　俊樹
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-20KK0181
[Presentation] 成人T細胞白血病リンパ腫を標的とする抗CADM1scFvの機能解析2023
- Author(s)
  田部亜季、高橋良明、中野和民、由井杏奈、中木戸誠、久世望、中村碧、石井洋、立川愛、俣野哲郎、渡邉俊樹、津本浩平
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] 新規抗CADM1抗体を用いた抗体薬物複合体の生体内動体と効果の検討2023
- Author(s)
  中野和民、田部亜季、高橋良明、由井杏奈、中木戸誠、内丸薫、渡邉俊樹、津本浩平
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] HTLV-1 type-aとtype-cのウイルス特性と病原性の違いに関する研究：ウイルス学的比較解析の試み2023
- Author(s)
  中野和民、田部亜季、佐藤知雄、鴨居功樹、宇都宮與、Lloyd Einseadel、渡邉俊樹、
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] 新規CADM1抗体-FoxM1阻害剤複合体によるATL細胞への標的治療の試み2022
- Author(s)
  中野和民、田部亜季、高橋良明、山本奈央佳、津本浩平、渡邉俊樹、内丸薫
- Organizer
  第8回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] 抗CADM1抗体を用いた成人T細胞白血病・リンパ腫細胞に対する抗体薬物複合体の開発2022
- Author(s)
  田部亜季、高橋良明、那須智博、由井杏奈、中木戸誠、内丸薫、渡邉俊樹、津本浩平、中野和民
- Organizer
  第8回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] 新規抗CADM1モノクローナル抗体の作製：CloneYTH-W-2C22022
- Author(s)
  高橋良明、田部亜季、中野和民、渡邉俊樹、津本浩平
- Organizer
  第8回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15598
[Presentation] 新規抗CADM１抗体を用いた成人T細胞白血病・リンパ腫細胞に対する抗体薬物複合体の開発2022
- Author(s)
  田部亜季、高橋良明、那須智博、由井杏奈、中木戸誠、内丸薫、渡邉俊樹、津本浩平、中野和民
- Organizer
  第8回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-20KK0181
[Presentation] 新規CADM1抗体-FoxM1阻害剤複合体によるATL細胞への標的治療の試み2022
- Author(s)
  中野和民、田部亜季、高橋良明、山本菜央佳、津本浩平、渡邉俊樹、内丸薫
- Organizer
  第8回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-20KK0181
[Presentation] aHUSに関連する補体抑制因子CFHと診断薬取得に向けた特異的抗体の機能解析2021
- Author(s)
  横尾尚典、田部亜季、中木戸誠、長門石曉、Martinez Caaveiro Jose Manuel、吉田瑶子、池田洋一郎、南学正臣、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20K16377
[Presentation] HTLV-1感染細胞とindolent ATLを標的とする抗OX40抗体薬物複合体開発2021
- Author(s)
  田部亜季、那須智博、高橋良明、田中勇悦、内丸薫、渡邉俊樹、津本浩平、中野和民
- Organizer
  第7回HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16377
[Presentation] Development of antibody-drug conjugate targeting adult T-cell leukemia/lymphoma cells with a new anti-CADM1 antibody2021
- Author(s)
  Aki Tanabe and Yoshiaki Takahashi, Tomohiro Nasu, Anna Yui, Makoto Nakakido, Kaoru Uchimaru, Toshiki Watanabe, Kouhei Tsumoto, Kazumi Nakano
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K16377
[Presentation] The mechanism by which positive supercharging mutations confer pH-independent thermal stability of an antibody2021
- Author(s)
  笠原慶亮・黒田大祐・河出来時・田部亜季・長門石曉・津本浩平
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19H04202
[Presentation] 機能化リンクモジュールの開発とECM模倣ハイドロゲルの創製2021
- Author(s)
  大川将志、田部亜季、太田誠一、長門石曉、津本浩平、伊藤大知
- Organizer
  日本膜学会第43年会
- Data Source
  KAKENHI-PROJECT-20K16377
[Presentation] 抗OX40抗体の受容体機能制御に関わる分子メカニズム解明2021
- Author(s)
  氏家寛，田部亜季，長門石曉，津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20K16377
[Presentation] 計算デザイン Supercharging 抗体の物性機能解析2020
- Author(s)
  笠原慶亮、黒田大祐、河出来時、田部亜季、長門石曉、津本浩平
- Organizer
  第48回　構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-20K16377
[Presentation] 成人T細胞白血病・リンパ腫（ATL)細胞に対する新規治療薬Darinaparsinの効果の検討とその作用機序解明の試み2020
- Author(s)
  那須　智博、田部　亜季、渡邉　俊樹、内丸　薫、中野　和民
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K16377
[Presentation] 抗OX40抗体の受容体機能制御に関わる分子メカニズム解明2020
- Author(s)
  氏家寛、田部亜季、伊村明浩、広瀬茂久、津本浩平
- Organizer
  第43回日本分子生物学会年、オンライン開催、2020年12月2日-4日
- Data Source
  KAKENHI-PROJECT-20K16377
[Presentation] aHUSに関連する補体抑制因子CFHと特異的抗体の機能解析2020
- Author(s)
  横尾尚典、田部亜季、中木戸誠、長門石曉、吉田瑶子、池田洋一郎、南学正臣、津本浩平
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K16377
[Presentation] 計算デザイン Supercharging 抗体の物性機能解析2020
- Author(s)
  笠原慶亮、黒田大祐、河出来時、田部亜季、長門石曉、津本浩平
- Organizer
  第48回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-19H04202
[Presentation] Production of rhTSG-6 using Expi293 expression system2019
- Author(s)
  Masashi Okawa, Aki Tanabe, Satoru Nagatoishi, Seiichi Ohta, Kohei Tsumoto, Taichi Ito
- Organizer
  The 14th Asian Congress on Biotechnology, July 1-4, 2019, Taiwan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21113
[Presentation] 成人T細胞白血病(ATL)を標的としたPhage display法による抗CADM1 scFvの取得2019
- Author(s)
  田部亜季
- Organizer
  蛋白質科学会
- Data Source
  KAKENHI-PROJECT-19K21113
[Presentation] 成人T細胞白血病(ATL)を標的としたPhage display法による抗CADM1 scFvの取得2019
- Author(s)
  田部亜季、中木戸誠、山本菜央佳、中野和民、内丸薫、津本浩平
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Data Source
  KAKENHI-PROJECT-19K21113

1. Kuroda Daisuke (60756732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. Nakano Kazumi (60549591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 森本淳平 (70754935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 渡邉俊樹 (30182934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 佐藤知雄 (30387063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 鴨居功樹 (40451942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 宇都宮與 (40511663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. NAGATOISHI Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. 津本浩平

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
10. 渡辺俊樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
11. 大杉剛生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 中木戸誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

tanabe aki 田部 亜季

Tanabe Aki 田部 亜季

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Development of novel therapeutics targeting Adult T-cell lukemia Lymphoma.Principal Investigator

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Japan-Australia joint study for epidemiological survey of HTLV-1 a/c subtypes and elucidation of their unique pathogenic mechanims

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Development of novel antibody-drug conjugate for refractory hematological malignancy and autoimmune diseasePrincipal Investigator

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Molecular design of real proteins in virtual space

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Thiostrepton Antibody-Drug Conjugate Targeting CADM1 for Adult T-Cell Leukemia/Lymphoma TherapyPrincipal Investigator

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[Book] 抗体薬物複合体(ADC)の設計・合成と最新動向2024

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[Journal Article] Analytical Method for Experimental Validation of Computer-Designed Antibody2022

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[Journal Article] Thrombophlebitis Migrans As the Prodrome of Adult T-Cell Leukemia-Lymphoma2022

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[Journal Article] Elucidation of the mechanism of host NMD suppression by HTLV-1 Rex: Dissection of Rex to identify the NMD inhibitory domain2022

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[Journal Article] Tuning Rex rules HTLV-1 pathogenesis2022

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[Journal Article] Exploring New Functional Aspects of HTLV-1 RNA-Binding Protein Rex: How Does Rex Control Viral Replication?2022

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[Journal Article] Antibody recognition of complement Factor H reveals a flexible loop involved in Atypical Hemolytic Uremic Syndrome pathogenesis2022

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[Journal Article] Extracellular matrix-inspired hydrogel of hyaluronan and gelatin crosslinked via a Link module with a transglutaminase reactive sequence2022

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[Journal Article] Correction: Antibody recognition of complement factor H reveals a flexible loop involved in atypical hemolytic uremic syndrome pathogenesis2022

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tanabe aki 田部亜季

Tanabe Aki 田部亜季