Uchiyama Hiromasa 内山博雅

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Hiromasa Uchiyama 内山博雅

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Researcher Number	60792744
Other IDs
Affiliation (Current)	2025: 大阪医科薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2024: 大阪医科薬科大学, 薬学部, 講師 2021 – 2022: 大阪医科薬科大学, 薬学部, 講師 2020: 大阪薬科大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator アモルファス / 経口吸収性改善 / 溶解性改善 / 分子間相互作用 / 中分子 / 難吸収性 / 難溶解性 / 中分子化合物 / CYP / コアモルファス

Strategic development of coamorphous formation technology that enables both improved solubility and taking medicinePrincipal Investigator
- Principal Investigator
  
  内山博雅
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Construction of drug development strategies for middle-molecule drug with low solubility and absorption based on coamorphous formationPrincipal Investigator
- Principal Investigator
  
  Hiromasa Uchiyama
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Osaka Medical and Pharmaceutical University
  Osaka University of Pharmaceutical Sciences

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Effect of Solubility Improvement <i>via</i> Formation of an Amorphous Composite of Indomethacin and Sulindac on Membrane Permeability2023
- Author(s)
  Yuta Hatanaka, Hiromasa Uchiyama, Shingo Furukawa, Mai Takase, Shinya Yamanaka, Kazunori Kadota, Yuichi Tozuka
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 71 Issue: 3 Pages: 257-261
- DOI
  10.1248/cpb.c22-00847
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2023-03-01
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07191
[Journal Article] The formation of an amorphous composite between flavonoid compounds: Enhanced solubility in both oil components and aqueous media2022
- Author(s)
  Hiromasa Uchiyama, Taiga Ando, Kazunori Kadota, Yuichi Tozuka
- Journal Title
  
  Journal of Drug Delivery Science and Technology
  
  Volume: 62 Pages: 102410-102410
- DOI
  10.1016/j.jddst.2021.102410
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07191
[Journal Article] Improved solubility and permeability of both nifedipine and ketoconazole based on coamorphous formation with simultaneous dissolution behavior2021
- Author(s)
  Yuta Hatanaka, Hiromasa Uchiyama, Kazunori Kadota, Yuichi Tozuka
- Journal Title
  
  Journal of Drug Delivery Science and Technology
  
  Volume: 65 Pages: 102715-102715
- DOI
  10.1016/j.jddst.2021.102715
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07191
[Presentation] Telmisartan-Amlodipineコアモルファス形成による難溶性薬物の吸収性改善.2023
- Author(s)
  畑中友太、内山博雅、門田和紀、戸塚裕一
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K07191
[Presentation] 異なる分子間相互作用様式を持つ非晶質複合体粒子からの薬物の膜透過性に関する検討.2022
- Author(s)
  内山博雅、河合晴香、畑中友太、門田和紀、戸塚裕
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-20K07191
[Presentation] イオン間相互作用を介した非晶質複合体の薬物溶解度と膜透過性の関係性評価.2022
- Author(s)
  畑中友太、内山博雅、門田和紀、戸塚裕一
- Organizer
  日本薬剤学会第47年会製剤・創剤セミナー
- Data Source
  KAKENHI-PROJECT-20K07191
[Presentation] CYP3A4の阻害剤を基剤に用いたコアモルファス設計とその評価2022
- Author(s)
  畑中友太、内山博雅、門田和紀、戸塚裕一
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-20K07191
[Presentation] 噴霧乾燥法に基づいた新規な非晶質製剤化技術の構築とその応用2022
- Author(s)
  内山博雅
- Organizer
  製剤技術学会第32回大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07191
[Presentation] 膜透過性改善を指向したコアモルファス技術の構築とエマルションへの応用.2020
- Author(s)
  内山博雅、花本夕華、門田和紀、戸塚裕一
- Organizer
  70回日本薬学会関西支部会
- Data Source
  KAKENHI-PROJECT-20K07191

1. 戸塚裕一 (50312963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. 門田和紀 (50709516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

Uchiyama Hiromasa 内山 博雅

Hiromasa Uchiyama 内山 博雅

Research Projects

Research Products

Co-Researchers

Strategic development of coamorphous formation technology that enables both improved solubility and taking medicinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction of drug development strategies for middle-molecule drug with low solubility and absorption based on coamorphous formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Effect of Solubility Improvement <i>via</i> Formation of an Amorphous Composite of Indomethacin and Sulindac on Membrane Permeability2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] The formation of an amorphous composite between flavonoid compounds: Enhanced solubility in both oil components and aqueous media2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Improved solubility and permeability of both nifedipine and ketoconazole based on coamorphous formation with simultaneous dissolution behavior2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Telmisartan-Amlodipineコアモルファス形成による難溶性薬物の吸収性改善.2023

Author(s)

Organizer

Data Source

[Presentation] 異なる分子間相互作用様式を持つ非晶質複合体粒子からの薬物の膜透過性に関する検討.2022

Author(s)

Organizer

Data Source

[Presentation] イオン間相互作用を介した非晶質複合体の薬物溶解度と膜透過性の関係性評価.2022

Author(s)

Organizer

Data Source

[Presentation] CYP3A4の阻害剤を基剤に用いたコアモルファス設計とその評価2022

Author(s)

Organizer

Data Source

[Presentation] 噴霧乾燥法に基づいた新規な非晶質製剤化技術の構築とその応用2022

Author(s)

Organizer

Data Source

[Presentation] 膜透過性改善を指向したコアモルファス技術の構築とエマルションへの応用.2020

Author(s)

Organizer

Data Source

Uchiyama Hiromasa 内山博雅

Hiromasa Uchiyama 内山博雅