OSAKO Yoichi 大迫洋一

Researcher Number	60793354
Affiliation (Current)	2025: 鹿児島大学, 医歯学域鹿児島大学病院, 助教
Affiliation (based on the past Project Information) *help	2024: 鹿児島大学, 医歯学域鹿児島大学病院, 助教 2021: 鹿児島大学, 鹿児島大学病院, 医員 2020 – 2021: 鹿児島大学, 医歯学総合研究科, 客員研究員 2019: 鹿児島大学, 鹿児島大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related Except Principal Investigator Basic Section 56030:Urology-related
Keywords	Principal Investigator 腎癌 / メチル化 / セリン / 治療抵抗性 / PHGDH / 膀胱癌 Except Principal Investigator 抗癌剤耐性 / WDR62 / miR-223 / PHGDH … More / SMARCD1 / miR-99a-5p / 膀胱癌 / ジェムシタビン耐性 / ジェムシタビン / シスプラチン / マイクロRNA / 薬剤耐性 / 尿路上皮癌 Less

治療抵抗性腎癌におけるSCG2を介した代謝リプログラミングの解明と新規治療戦略の開発Principal Investigator
- Principal Investigator
  
  大迫洋一
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kagoshima University
Targeting the Serine Synthesis Pathway as a Potential Novel Bladder Cancer Therapy and the elucidation of its Expression MechanismPrincipal Investigator
- Principal Investigator
  
  OSAKO Yoichi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kagoshima University
Elucidating anticancer drug resistance in urothelial carcinoma by multi-faceted approach
- Principal Investigator
  
  NAKAGAWA Masayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kagoshima University

All 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] microRNA-99a-5p induces cellular senescence in gemcitabine-resistant bladder cancer by targeting SMARCD1.2022
- Author(s)
  Motoki Tamai, Shuichi Tatarano, Shunsuke Okamura, Wataru Fukumoto, Issei Kawakami, Yoichi Osako, Takashi Sakaguchi, Satoshi Sugita, Masaya Yonemori, Yasutoshi Yamada, Masayuki Nakagawa, Hideki Enokida, Hirofumi Yoshino.
- Journal Title
  
  Molecular Oncology
  
  Volume: 16 Issue: 6 Pages: 1329-1346
- DOI
  10.1002/1878-0261.13192
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09715, KAKENHI-PROJECT-20K18146, KAKENHI-PROJECT-21K09404, KAKENHI-PROJECT-22K09452, KAKENHI-PROJECT-22K09478
[Journal Article] EHHADH contributes to cisplatin resistance through regulation by tumor-suppressive microRNAs in bladder cancer2021
- Author(s)
  Okamura Shunsuke、Yoshino Hirofumi、Kuroshima Kazuki、Tsuruda Masafumi、Osako Yoichi、Sakaguchi Takashi、Yonemori Masaya、Yamada Yasutoshi、Tatarano Shuichi、Nakagawa Masayuki、Enokida Hideki
- Journal Title
  
  BMC Cancer
  
  Volume: 21 Issue: 1 Pages: 48-48
- DOI
  10.1186/s12885-020-07717-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18146, KAKENHI-PROJECT-18K09198, KAKENHI-PROJECT-19K18615
[Journal Article] Characterization of PHGDH expression in bladder cancer: potential targeting therapy with gemcitabine/cisplatin and the contribution of promoter DNA hypomethylation2020
- Author(s)
  Hirofumi Yoshino, Hideki Enokida, Yoichi Osako, Nijiro Nohata, Masaya Yonemori, Satoshi Sugita, Kazuki Kuroshima, Masafumi Tsuruda, Shuichi Tatarano, Masayuki Nakagawa.
- Journal Title
  
  Molecular Oncology
  
  Volume: 54 Issue: 9 Pages: 2190-2202
- DOI
  10.1002/1878-0261.12697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09715, KAKENHI-PROJECT-20K18146, KAKENHI-PROJECT-18K09198, KAKENHI-PROJECT-19K18615
[Journal Article] Tumor suppressive microRNA223 targets WDR62 directly in bladder cancer.2019
- Author(s)
  Sugita S, Yoshino H, Yonemori M, Miyamoto K, Matsushita R, Sakaguchi T, Itesako T, Tatarano S, Nakagawa M, Enokida H.
- Journal Title
  
  Int J Oncol.
  
  Volume: 54 Pages: 2222-2236
- DOI
  10.3892/ijo.2019.4762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04332, KAKENHI-PROJECT-17K16799, KAKENHI-PROJECT-19K07736, KAKENHI-PROJECT-19K09715, KAKENHI-PROJECT-19K18615
[Presentation] PHGDHを標的とした新規膀胱癌治療の可能性とその発現機構の解明2021
- Author(s)
  吉野裕史, 大迫洋一, 鶴田雅史, 黒島和樹, 岡村俊介, 榎田英樹, 中川昌之.
- Organizer
  第30回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-20K18146
[Presentation] PHGDHを標的とした新規膀胱癌治療の可能性とその発現機構の解明2021
- Author(s)
  吉野裕史、大迫洋一、鶴田雅史、黒島和樹、岡村俊介、榎田英樹、中川昌之
- Organizer
  第109回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-20K18146
[Presentation] シスプラチン耐性膀胱癌に対する治療標的型microRNAと標的遺伝子の探索2020
- Author(s)
  岡村俊介, 吉野裕史, 大迫洋一, 黒島和樹, 鶴田雅史, 榎田英樹, 中川昌之.
- Organizer
  第108回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-20K18146

1. NAKAGAWA Masayuki (90164144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 榎田英樹 (80347103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 吉野裕史 (90642611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

OSAKO Yoichi 大迫 洋一

Research Projects

Research Products

Co-Researchers

治療抵抗性腎癌におけるSCG2を介した代謝リプログラミングの解明と新規治療戦略の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Targeting the Serine Synthesis Pathway as a Potential Novel Bladder Cancer Therapy and the elucidation of its Expression MechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating anticancer drug resistance in urothelial carcinoma by multi-faceted approach

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] microRNA-99a-5p induces cellular senescence in gemcitabine-resistant bladder cancer by targeting SMARCD1.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] EHHADH contributes to cisplatin resistance through regulation by tumor-suppressive microRNAs in bladder cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of PHGDH expression in bladder cancer: potential targeting therapy with gemcitabine/cisplatin and the contribution of promoter DNA hypomethylation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tumor suppressive microRNA223 targets WDR62 directly in bladder cancer.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] PHGDHを標的とした新規膀胱癌治療の可能性とその発現機構の解明2021

Author(s)

Organizer

Data Source

[Presentation] PHGDHを標的とした新規膀胱癌治療の可能性とその発現機構の解明2021

Author(s)

Organizer

Data Source

[Presentation] シスプラチン耐性膀胱癌に対する治療標的型microRNAと標的遺伝子の探索2020

Author(s)

Organizer

Data Source

OSAKO Yoichi 大迫洋一