Takahashi Motoko 高橋元子

… Alternative Names

高橋元子タカハシモトコ

TAKAHASHI Motoko 高橋元子

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Researcher Number	60793594
Other IDs
Affiliation (Current)	2026: 公益財団法人がん研究会, がん研究所実験病理部, 客員研究員
Affiliation (based on the past Project Information) *help	2024: 公益財団法人がん研究会, がん研究所実験病理部, 博士研究員 2023: 公益財団法人がん研究会, がん研究所実験病理部, 研究員 2021: 公益財団法人がん研究会, がん研究所実験病理部, 特任研究員 2018 – 2021: 公益財団法人がん研究会, がん研究所実験病理部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related
Keywords	Principal Investigator コンデンシン / タンパク質間相互作用 / KIF4A / 分裂期染色体 / 染色体凝縮機構 / 分子クラスター / クロマチン / SMC複合体 / 細胞周期 / 複製 … More / 転写 / 染色体凝縮 / 二本鎖DNA / 一本鎖DNA Less

動的タンパク質集合体が駆動する染色体構築Principal Investigator
- Principal Investigator
  
  高橋元子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Japanese Foundation for Cancer Research
The regulation of condensin complex reveals cooperation between transcription or duplication and chromosome organization.Principal Investigator
- Principal Investigator
  
  TAKAHASHI Motoko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Japanese Foundation for Cancer Research

All 2024 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Kinetochore stretching-mediated rapid silencing of the spindle-assembly checkpoint required for failsafe chromosome segregation2021
- Author(s)
  Uchida Kazuhiko S.K.、Jo Minji、Nagasaka Kota、Takahashi Motoko、Shindo Norihisa、Shibata Katsushi、Tanaka Kozo、Masumoto Hiroshi、Fukagawa Tatsuo、Hirota Toru
- Journal Title
  
  Current Biology
  
  Volume: - Issue: 8 Pages: 1581-1591.e3
- DOI
  10.1016/j.cub.2021.01.062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07677, KAKENHI-PROJECT-20K21395, KAKENHI-PROJECT-17H06167, KAKENHI-PUBLICLY-20H05389, KAKENHI-PROJECT-18H02434, KAKENHI-PROJECT-18K14629, KAKENHI-PUBLICLY-21H05738, KAKENHI-PUBLICLY-21H05752, KAKENHI-PROJECT-18H04034, KAKENHI-PROJECT-20H00473
[Journal Article] Nuclear microenvironment in cancer: Control through liquid‐liquid phase separation2020
- Author(s)
  Nozawa Ryu‐Suke、Yamamoto Tatsuro、Takahashi Motoko、Tachiwana Hiroaki、Maruyama Reo、Hirota Toru、Saitoh Noriko
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 9 Pages: 3155-3163
- DOI
  10.1111/cas.14551
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14629, KAKENHI-PROJECT-20H03190, KAKENHI-PROJECT-20H03520, KAKENHI-PROJECT-18K19310, KAKENHI-PLANNED-18H05531
[Journal Article] Folding the genome into mitotic chromosomes2019
- Author(s)
  Motoko Takahashi, Toru Hirota
- Journal Title
  
  Current Opinion in Cell Biology
  
  Volume: 60 Pages: 19-26
- DOI
  10.1016/j.ceb.2019.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14629, KAKENHI-ORGANIZER-15H05970, KAKENHI-PLANNED-15H05977, KAKENHI-PROJECT-18H04034
[Journal Article] Dynamics of sister chromatids through the cell cycle: Together and apart2018
- Author(s)
  Takahashi Motoko、Hirota Toru
- Journal Title
  
  The Journal of Cell Biology
  
  Volume: 217 Issue: 6 Pages: 1887-1889
- DOI
  10.1083/jcb.201804091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14629, KAKENHI-PLANNED-15H05977, KAKENHI-PROJECT-18H04034
[Presentation] Higher order molecular assembly drives chromosome organization.2024
- Author(s)
  Takahashi, M., Liu, C., Hirota, T.
- Organizer
  Jacques Monod Conference (Roscoff Cell Cycle Meeting)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14128
[Presentation] How Plk1 activity is regulated by conformational transition2024
- Author(s)
  劉暢, 高橋元子, 広田亨
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K14128
[Presentation] 16.How molecular clustering can drive mitotic chromosome assembly in mitosis2024
- Author(s)
  高橋元子, 劉暢, 広田亨
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K14128
[Presentation] 分子構造変換によるPlk1の活性制御機構の解析2024
- Author(s)
  劉暢, 高橋元子, 広田亨
- Organizer
  第3回細胞分裂研究会
- Data Source
  KAKENHI-PROJECT-23K14128
[Presentation] Macromolecular clustering drives mitotic chromosome assembly2024
- Author(s)
  Takahashi, M., Liu, C., Hirota, T.
- Organizer
  The 12th 3R+3C International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14128
[Presentation] How Condensin I and KIF4A drive mitotic chromosome assembly in mitosis2024
- Author(s)
  Takahashi, M., Liu, C., Hirota, T.
- Organizer
  NIG & RIKEN international Symposium 2024 SMC Complexes : Orchestrating Diverse Genome Functions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14128
[Presentation] A strategy to intervene mitotic kinases to induce mitotic catastrophe in cancer cells2024
- Author(s)
  Takahashi, M., Jo, M., Kamakura, N., Liu, C., Kato, U., Hirota, T.
- Organizer
  AACR Annual Meeting 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14128
[Presentation] Targeting chromosomal instability in cancer2024
- Author(s)
  高橋元子, 趙民知, 鎌倉奈々, 劉暢, 加藤詩子, 広田亨
- Organizer
  第83回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K14128
[Presentation] The chromosome organization depends on dynamic interactions between condensin and chromosomal axial proteins2021
- Author(s)
  Motoko Takahashi, Toru Hirota
- Organizer
  第80回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18K14629
[Presentation] Single stranded DNA in interphase is a key chromatin structure for mitotic chromosome organization2018
- Author(s)
  Takahashi M, Hirota T
- Organizer
  第77回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14629
[Presentation] Single stranded DNA in interphase is a key chromatin structure for mitotic chromosome organization2018
- Author(s)
  Takahashi M, Hirota T
- Organizer
  The 11th 3R & 3C Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14629
[Presentation] Characterization of DNA binding mode of human condensin I and II2018
- Author(s)
  Takahashi M, Hirota T
- Organizer
  The 7th Chromosome OS meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14629

1. 進藤軌久

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# of Collaborated Products: 1 results

Takahashi Motoko 高橋 元子

高橋 元子 タカハシ モトコ

TAKAHASHI Motoko 高橋 元子

Research Projects

Research Products

Co-Researchers

動的タンパク質集合体が駆動する染色体構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The regulation of condensin complex reveals cooperation between transcription or duplication and chromosome organization.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Kinetochore stretching-mediated rapid silencing of the spindle-assembly checkpoint required for failsafe chromosome segregation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear microenvironment in cancer: Control through liquid‐liquid phase separation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Folding the genome into mitotic chromosomes2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamics of sister chromatids through the cell cycle: Together and apart2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Higher order molecular assembly drives chromosome organization.2024

Author(s)

Organizer

Data Source

[Presentation] How Plk1 activity is regulated by conformational transition2024

Author(s)

Organizer

Data Source

[Presentation] 16.How molecular clustering can drive mitotic chromosome assembly in mitosis2024

Author(s)

Organizer

Data Source

[Presentation] 分子構造変換によるPlk1の活性制御機構の解析2024

Author(s)

Organizer

Data Source

[Presentation] Macromolecular clustering drives mitotic chromosome assembly2024

Author(s)

Organizer

Data Source

[Presentation] How Condensin I and KIF4A drive mitotic chromosome assembly in mitosis2024

Author(s)

Organizer

Data Source

[Presentation] A strategy to intervene mitotic kinases to induce mitotic catastrophe in cancer cells2024

Author(s)

Organizer

Data Source

[Presentation] Targeting chromosomal instability in cancer2024

Author(s)

Organizer

Data Source

[Presentation] The chromosome organization depends on dynamic interactions between condensin and chromosomal axial proteins2021

Author(s)

Organizer

Data Source

[Presentation] Single stranded DNA in interphase is a key chromatin structure for mitotic chromosome organization2018

Author(s)

Organizer

Data Source

[Presentation] Single stranded DNA in interphase is a key chromatin structure for mitotic chromosome organization2018

Author(s)

Takahashi Motoko 高橋元子

高橋元子タカハシモトコ

TAKAHASHI Motoko 高橋元子