KONDO TAISUKE 近藤泰介

Researcher Number	60803765
Other IDs	https://orcid.org/0000-0002-8545-1251
Affiliation (based on the past Project Information) *help	2017 – 2019: 慶應義塾大学, 医学部(信濃町), 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Pathological medical chemistry
Keywords	Principal Investigator 細胞移入療法 / ミトコンドリア / 免疫記憶 / 腫瘍免疫学 / 代謝制御 / 腫瘍免疫 / 白血病 / 免疫代謝 / がん免疫療法 / CAR-T療法 … More / 代謝 / がん免疫 / メタボリズム / がん免疫学 / 代謝学 Less

Metabolic Reprogramming Requires Stem Cell Memory T Cell phenotypes for Cancer ImmunotherapyPrincipal Investigator
- Principal Investigator
  
  KONDO TAISUKE
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Keio University
NotchシグナルによるステムセルメモリーＴ細胞の誘導と細胞移入療法への応用Principal Investigator
- Principal Investigator
  
  近藤泰介
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Keio University

All 2020 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] The NOTCH-FOXM1 Axis Plays a Key Role in Mitochondrial Biogenesis in the Induction of Human Stem Cell Memory-like CAR-T Cells.2020
- Author(s)
  Kondo T, Ando M, Nagai N, Tomisato W, Srirat T, Liu B, Mise-Omata S, Ikeda M, Chikuma S, Nishimasu H, Nureki O, Ohmura M, Hayakawa N, Hishiki T, Uchibori R, Ozawa K, Yoshimura A
- Journal Title
  
  Cancer Res
  
  Volume: 80 Issue: 3 Pages: 471-483
- DOI
  10.1158/0008-5472.can-19-1196
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07488, KAKENHI-PROJECT-19K07514, KAKENHI-PROJECT-19K23850, KAKENHI-PUBLICLY-19H04816, KAKENHI-PROJECT-20K20384, KAKENHI-PROJECT-18K15290, KAKENHI-PROJECT-16H06276
[Journal Article] Generation and application of human induced-stem cell memory T cells for adoptive immunotherapy.2018
- Author(s)
  Taisuke Kondo Yuki Imura Shunsuke Chikuma Sana Hibino Setsuko Omata‐Mise Makoto Ando Takashi Akanuma Mana Iizuka Ryota Sakai Rimpei Morita Akihiko Yoshimura
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 7 Pages: 2130-2140
- DOI
  10.1111/cas.13648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15290, KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-16K09867, KAKENHI-PROJECT-16K15292, KAKENHI-PROJECT-17K19398, KAKENHI-PROJECT-20K20384, KAKENHI-PROJECT-16H05178
[Journal Article] Inhibition of Nr4a receptors enhances anti-tumor immunity by breaking Treg-mediated immune tolerance.2018
- Author(s)
  Hibino S, Chikuma S, Kondo T, Ito M, Nakatsukasa H, Omata-Mise S, Yoshimura A
- Journal Title
  
  Cancer Res
  
  Volume: Epub Issue: 11 Pages: 3027-3040
- DOI
  10.1158/0008-5472.can-17-3102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-17H07088, KAKENHI-PROJECT-15J03260, KAKENHI-PROJECT-15J07566, KAKENHI-PROJECT-18K15198, KAKENHI-PROJECT-16K09867, KAKENHI-PROJECT-16K15292, KAKENHI-PROJECT-20K20384
[Journal Article] Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation2017
- Author(s)
  Someya Kazue、Nakatsukasa Hiroko、Ito Minako、Kondo Taisuke、Tateda Kenn-ichi、Akanuma Takashi、Koya Ikuko、Sanosaka Tsukasa、Kohyama Jun、Tsukada Yu-ichi、Takamura-Enya Takeji、Yoshimura Akihiko
- Journal Title
  
  International Immunology
  
  Volume: 29 Issue: 8 Pages: 365-375
- DOI
  10.1093/intimm/dxx049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00562, KAKENHI-PROJECT-16K15292, KAKENHI-PROJECT-17K19398, KAKENHI-PLANNED-25112008, KAKENHI-PROJECT-17H07088, KAKENHI-PROJECT-15J03260, KAKENHI-PROJECT-15J07468
[Journal Article] Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy2017
- Author(s)
  Taisuke Kondo, Rimpei Morita, Yuumi Okuzono, Hiroko Nakatsukasa, Takashi Sekiya, Shunsuke Chikuma, Takashi Shichita, Mitsuhiro Kanamori, Masato Kubo, Keiko Koga, Takahiro Miyazaki, Yoshiaki Kassai, Akihiko Yohimura
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 15338-15338
- DOI
  10.1038/ncomms15338
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0114, KAKENHI-PROJECT-16K15292, KAKENHI-PROJECT-16H05178, KAKENHI-PROJECT-17H07088
[Journal Article] Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells.2017
- Author(s)
  Okada M, Chikuma S et al.
- Journal Title
  
  Cell Reports
  
  Volume: 20 Issue: 5 Pages: 1017-1028
- DOI
  10.1016/j.celrep.2017.07.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08847, KAKENHI-PROJECT-17K15451, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-17H03600, KAKENHI-PROJECT-17H07088, KAKENHI-PROJECT-15J07566, KAKENHI-PROJECT-15K19128
[Journal Article] Generation of alloantigen-specific induced-Treg stabilized by vitamin C treatment and its application for prevention of acute graft versus host disease model2017
- Author(s)
  Hidenori Kasahara, Taisuke Kondo, Hiroko Nakatsukasa, Shunsuke Chikuma, Minako Ito, Makoto Ando, Yutaka Kurebayashi, Takashi Sekiya, Taketo Yamada, Shinichiro Okamoto, Akihiko Yoshimura
- Journal Title
  
  International Immunology
  
  Volume: 29 Issue: 10 Pages: 457-469
- DOI
  10.1093/intimm/dxx060
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0114, KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-17H07088, KAKENHI-PROJECT-15J03260, KAKENHI-PROJECT-16J07143
[Patent] ＣＤ４５ＲＡ＋およびＣＣＲ７＋の細胞表面マーカーを有するＴ細胞の製造方法2019
- Inventor(s)
  近藤泰介、吉村昭彦、慶應義塾大学、第一三共
- Industrial Property Rights Holder
  慶應義塾大学、第一三共
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-195206
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K15290
[Presentation] Metabolic Reprogramming requires Stem Cell Memory T Cells phenotypes for Adoptive Immunotherapy2018
- Author(s)
  近藤泰介
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K15290
[Presentation] ミトコンドリア制御によるステムセルメモリーT細胞の誘導と細胞移入療法への応用2018
- Author(s)
  近藤泰介
- Organizer
  日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-18K15290
[Presentation] Metabolic Reprogramming Induces Stem Cell Memory T Cells for Adoptive Immunotherapy2018
- Author(s)
  Taisuke Kondo, Rimpei Morita, Akihiko Yoshimura
- Organizer
  ①2017 Keystone Symposia Conference X1: Immunological Memory: Innate, Adaptive and Beyond
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07088
[Presentation] Notchシグナルによる活性化T細胞からステムセルメモリーT細胞への転換と免疫療法への応用2017
- Author(s)
  近藤泰介
- Organizer
  がん免疫学会
- Data Source
  KAKENHI-PROJECT-17H07088
[Presentation] Notch-mediated conversion of activated T cells into stem cell memory T cells facilitates adoptive cancer immunotherapy2017
- Author(s)
  Taisuke Kondo, Rimpei Morita, Akihiko Yoshimura
- Organizer
  ②The 5th Annual Meeting of the International Cytokine and Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07088

1. TAKAMURA Takeji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 竹馬俊介

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
3. 関谷高史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

KONDO TAISUKE 近藤 泰介

Research Projects

Research Products

Co-Researchers

Metabolic Reprogramming Requires Stem Cell Memory T Cell phenotypes for Cancer ImmunotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

NotchシグナルによるステムセルメモリーＴ細胞の誘導と細胞移入療法への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The NOTCH-FOXM1 Axis Plays a Key Role in Mitochondrial Biogenesis in the Induction of Human Stem Cell Memory-like CAR-T Cells.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation and application of human induced-stem cell memory T cells for adoptive immunotherapy.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of Nr4a receptors enhances anti-tumor immunity by breaking Treg-mediated immune tolerance.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of alloantigen-specific induced-Treg stabilized by vitamin C treatment and its application for prevention of acute graft versus host disease model2017

Author(s)

Journal Title

DOI

Data Source

[Patent] ＣＤ４５ＲＡ＋およびＣＣＲ７＋の細胞表面マーカーを有するＴ細胞の製造方法2019

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] Metabolic Reprogramming requires Stem Cell Memory T Cells phenotypes for Adoptive Immunotherapy2018

Author(s)

Organizer

Data Source

[Presentation] ミトコンドリア制御によるステムセルメモリーT細胞の誘導と細胞移入療法への応用2018

Author(s)

Organizer

Data Source

[Presentation] Metabolic Reprogramming Induces Stem Cell Memory T Cells for Adoptive Immunotherapy2018

Author(s)

Organizer

Data Source

[Presentation] Notchシグナルによる活性化T細胞からステムセルメモリーT細胞への転換と免疫療法への応用2017

Author(s)

Organizer

Data Source

[Presentation] Notch-mediated conversion of activated T cells into stem cell memory T cells facilitates adoptive cancer immunotherapy2017

Author(s)

Organizer

Data Source

KONDO TAISUKE 近藤泰介