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Kasai Yoshiyuki  葛西 善行

ORCIDConnect your ORCID iD *help
Researcher Number 60813889
Other IDs
Affiliation (based on the past Project Information) *help 2018 – 2023: 東京慈恵会医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 56050:Otorhinolaryngology-related
Except Principal Investigator
Basic Section 56050:Otorhinolaryngology-related
Keywords
Principal Investigator
in vitro実験 / 中耳再生治療 / 細胞シート / クリアランス能 / 線毛機能 / トランスクリプトーム / 再生医療 / 作用機序の解明 / カルシウムイオン / ROCKインヒビター / ミオシン … More
Except Principal Investigator
… More 細胞シート / 再生医療 / 鼻腔粘膜 / 癒着性中耳炎 / 細胞移植 / 耳管開放症 / 成熟脂肪細胞 / 脂肪由来間葉系幹細胞 / 再生治療 / 耳管閉鎖障害 / 粘膜細胞シート / ハイブリッド / 培養細胞 / 耳科手術 / ラット中耳粘膜剥離モデル / 骨粉 / 骨髄由来間葉系幹細胞 / 鼻粘膜組織由来上皮細胞 / ハイブリッド耳科手術材料 / 骨パテ / 中耳粘膜 / 粘膜再生 / 動物モデル実験 / In vivo実験 / Ex vivo実験 / 作用機序の解明 / 移植後の機能 / 作用機序 / 鼻腔粘膜細胞シート / 動物実験 / 作用機序解明 / 中耳再生治療 / 中耳粘膜再生 / 凍結細胞 / 細胞培養 / 真珠腫性中耳炎 Less
  • Research Projects

    (7 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (7 People)
  •  Development of a novel treatment for Eustachian tube obstruction using regenerative medicine

    • Principal Investigator
      小島 博己
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Jikei University School of Medicine
  •  癒着性中耳炎モデルにおける細胞シート移植の検討

    • Principal Investigator
      山本 和央
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Jikei University School of Medicine
  •  骨パテと培養細胞の複合によるハイブリッド耳科手術材料の開発

    • Principal Investigator
      山本 裕
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Jikei University School of Medicine
  •  Functional analysis for nasal mucosal cell sheet after graftingPrincipal Investigator

    • Principal Investigator
      葛西 善行
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Jikei University School of Medicine
  •  Elucidation for mechanism of the nasal mucosal cell sheet in middle ear regenerative therapy

    • Principal Investigator
      Kojima Hiromi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Jikei University School of Medicine
  •  Establishment of new preparation method for popularization of cell sheet treatment for intractable otitis media

    • Principal Investigator
      YAGUCHI YUICHIRO
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      St. Marianna University School of Medicine
  •  In vitro studies on the action mechanism of grafted nasal mucosal cell sheetPrincipal Investigator

    • Principal Investigator
      Kasai Yoshiyuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Jikei University School of Medicine

All 2022 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] Analysis of the potential of human cultured nasal epithelial cell sheets to differentiate into airway epithelium2022

    • Author(s)
      Kasai Yoshiyuki、Morino Tsunetaro、Nakayama Tsuguhisa、Yamamoto Kazuhisa、Kojima Hiromi
    • Journal Title

      FASEB BioAdvances

      Volume: 5 Issue: 3 Pages: 89-100

    • DOI

      10.1096/fba.2022-00106

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K16848
  • [Journal Article] Temporary Storage of the Human Nasal Tissue and Cell Sheet for Wound Repair2021

    • Author(s)
      Kasai Yoshiyuki、Morino Tsunetaro、Dobashi Izumi、Mori Eri、Yamamoto Kazuhisa、Kojima Hiromi
    • Journal Title

      Frontiers in Bioengineering and Biotechnology

      Volume: 9 Pages: 687946-687946

    • DOI

      10.3389/fbioe.2021.687946

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03806, KAKENHI-PROJECT-21K16848
  • [Journal Article] Cell sheet transplantation prevents inflammatory adhesions: A new treatment for adhesive otitis media2021

    • Author(s)
      Yamamoto Kazuhisa、Morino Tsunetaro、Kasai Yoshiyuki、Kikuchi Shun、Komori Manabu、Yamato Masayuki、Kojima Hiromi
    • Journal Title

      Regenerative Therapy

      Volume: 18 Pages: 457-463

    • DOI

      10.1016/j.reth.2021.10.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03806
  • [Journal Article] ROCK inhibitor combined with Ca2+ controls the myosin II activation and optimizes human nasal epithelial cell sheets2020

    • Author(s)
      Kasai Yoshiyuki、Morino Tsunetaro、Mori Eri、Yamamoto Kazuhisa、Kojima Hiromi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 16853-16853

    • DOI

      10.1038/s41598-020-73817-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03806, KAKENHI-PROJECT-18K16907
  • [Journal Article] Analysis of human nasal mucosal cell sheets fabricated using transported tissue and blood specimens2019

    • Author(s)
      Yoshiyuki Kasai,Tsunetaro Morino,Shun Kikuchi, Ryoto Mitsuyoshi, Masahiro Takahashi,a Kazuhisa Yamamoto,a Yuichiro Yaguchi
    • Journal Title

      Regenerative therapy

      Volume: 11 Pages: 88-94

    • DOI

      10.1016/j.reth.2019.05.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09332, KAKENHI-PROJECT-18K09357, KAKENHI-PROJECT-19K18785, KAKENHI-PROJECT-19K18786
  • [Journal Article] Analysis of human nasal mucosal cell sheets fabricated using transported tissue and blood specimens2019

    • Author(s)
      Kasai Y, Morino T, Kikuchi S, Mitsuyoshi R, Takahashi M, Yamamoto K, Yaguchi Y, Yamato M, Kojima H
    • Journal Title

      Regen Ther

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K16907
  • [Presentation] 中耳再生医療における鼻腔粘膜細胞シートの作用機序解明を目指した基礎的研究2022

    • Author(s)
      葛西 善行, 森野 常太郎, 山本 和央, 小島 博己
    • Organizer
      第21回 日本再生医療学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K16848
  • [Presentation] 中耳再生医療における鼻腔粘膜細胞シートの作用機序解明を目指した基礎的研究2022

    • Author(s)
      葛西 善行
    • Organizer
      第21回日本再生医療学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03806
  • [Presentation] 鼻腔粘膜組織と細胞シートの保存法開発2021

    • Author(s)
      葛西 善行, 森野 常太郎, 森 恵莉, 山本 和央, 小島 博己
    • Organizer
      第20回 日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-18K16907
  • [Presentation] 鼻腔粘膜組織と細胞シートの保存法開発2021

    • Author(s)
      葛西 善行, 森野 常太郎, 森 恵莉, 山本 和央, 小島 博己
    • Organizer
      第20回 日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-19H03806
  • [Presentation] 治験を目指した鼻腔粘膜細胞シートの作製法の検討2019

    • Author(s)
      葛西 善行, 森野 常太郎, 山本 和央, 小島 博己
    • Organizer
      第18回 再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-18K16907
  • [Presentation] Two-way control of non-muscle myosin light chain activity plays a crucial role in epithelial cell sheet2019

    • Author(s)
      Kasai Y, Morino T, Yamamoto K, Kojima H
    • Organizer
      Cell symposium: Engineering Organoids and Organs
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16907
  • [Presentation] 培養鼻腔粘膜上皮細胞シートによる中耳粘膜再生を目的とした治療と製造販売に向けた試み2019

    • Author(s)
      小島 博己, 山本 和央, 森野 常太郎, 葛西 善行
    • Organizer
      第18回 再生医療学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K16907
  • [Presentation] Ex vivo studies of the behavior of nasal mucosal cell sheet after grafting2018

    • Author(s)
      Kasai Y, Morino T, Yamamoto K, Kojima H
    • Organizer
      5th Tissue engineering and regenerative medicine international society world congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16907
  • [Presentation] 培養上皮細胞シート移植による中耳粘膜再生治療 ~細胞シート治療の普及に向けた輸送システムの検討~2018

    • Author(s)
      谷口 雄一郎, 山本 和央, 森野 常太郎, 葛西 善行, 稲垣 太朗, 小島 博己, 肥塚 泉
    • Organizer
      第28回 日本耳科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-18K16907
  • [Presentation] Middle ear mucosal regeneration by tissue-engineered cell sheets transplantation2018

    • Author(s)
      Yamamoto K, Kasai Y, Morino T, Kojima H
    • Organizer
      6th East Asian Symposium on Otology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16907
  • 1.  森野 常太郎 (00796352)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 5 results
  • 2.  山本 和央 (50408449)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 5 results
  • 3.  Kojima Hiromi (60234762)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  山本 裕 (10313545)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  YAGUCHI YUICHIRO (30307475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  滝澤 悠己 (70836692)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  菊地 瞬 (70817262)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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