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NAGANO CHINA  長野 智那

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Nagano China  長野 智那

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Researcher Number 60814316
Other IDs
Affiliation (Current) 2025: 神戸大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help 2025: 神戸大学, 医学部附属病院, 助教
2023: 神戸大学, 医学研究科, 助教
2020 – 2022: 神戸大学, 医学研究科, 医学研究員
2020: 神戸大学, 医学研究科, 助教
2018 – 2019: 神戸大学, 医学研究科, 特命助教
Review Section/Research Field
Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related
Except Principal Investigator
Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53040:Nephrology-related
Keywords
Principal Investigator
WT1 / Frasier症候群 / Denys-Drash症候群 / 転写因子 / WT1遺伝子 / アンチセンス治療薬 / スプライシング
Except Principal Investigator
小児ネフローゼ症候群 / ネフリン / 疾患感受性遺伝子 … More / GWASメタ解析 / ネフローゼ症候群 / 抗ネフリン抗体 / 腎臓オルガノイド / iPS細胞 / 器官システム内科学 / 腎臓学 / フィンランド型先天性ネフローゼ症候群 / ゲノムワイド関連解析 / ステロイド感受性ネフローゼ症候群 Less
  • Research Projects

    (6 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (10 People)
  •  WT1関連異常症の病態解明と治療法開発Principal Investigator

    • Principal Investigator
      長野 智那
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kobe University
  •  WT1遺伝子異常症に対する病態解明と新規治療法の開発Principal Investigator

    • Principal Investigator
      長野 智那
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kobe University
  •  Joint international Research Project for International GWAS Meta-Analysis and Anti-Nephrin Autoantibodies in Childhood Nephrotic Syndrome

    • Principal Investigator
      Iijima Kazumoto
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Kobe University
  •  Clarification of the pathogenesis of childhood nephrotic syndrome using iPS cell-derived kidney organoids

    • Principal Investigator
      Iijima Kazumoto
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Kobe University
  •  Elucidation of pathogenicity and development of new treatment for Frasier syndromePrincipal Investigator

    • Principal Investigator
      Nagano China
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kobe University
  •  Joint International Research for identification of disease-susceptible genes and drug-sensitive genes in childhood nephrotic syndrome

    • Principal Investigator
      IIJIMA KAZUMOTO
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Kobe University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] WT1 exon 10 missense variant in a pediatric patient with focal segmental glomerulosclerosis with embryonal hyperplasia2024

    • Author(s)
      Kurokawa Mari、Nishimura Manao、Nishiyama Kei、Matsuoka Kentaro、Nagano China、Kaku Yoshitsugu
    • Journal Title

      Pediatric Nephrology

      Volume: - Issue: 7 Pages: 2083-2085

    • DOI

      10.1007/s00467-024-06293-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16926
  • [Journal Article] 【腎臓学この1年の進歩】ネフリンとネフローゼ症候群2024

    • Author(s)
      飯島 一誠, 堀之内 智子, 長野 智那, 野津 寛大
    • Journal Title

      日本腎臓学会誌

      Volume: 66巻 Pages: 303-309

    • Data Source
      KAKENHI-PROJECT-21KK0147
  • [Journal Article] Anti-nephrin antibodies in steroid-sensitive nephrotic syndrome in Japanese children2023

    • Author(s)
      Horinouchi Tomoko、Nagano China、Watts Andrew J. B.
    • Journal Title

      Pediatric Nephrology

      Volume: 39 Issue: 1 Pages: 337-337

    • DOI

      10.1007/s00467-023-06107-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0147, KAKENHI-PROJECT-23K27617
  • [Journal Article] Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome2023

    • Author(s)
      Barry A, McNulty MT, Jia X, Nagano C, Horinouchi T, Nozu K, Tokunaga K, Ronco P, Iijima K, Sampson MG, et al.
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 2481-2481

    • DOI

      10.1038/s41467-023-37985-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0147, KAKENHI-PROJECT-23K27617
  • [Journal Article] A multicenter retrospective study of calcineurin inhibitors in nephrotic syndrome secondary to podocyte gene variants2023

    • Author(s)
      Malakasioti G, Iancu D, Milovanova A, Tsygin A, Horinouchi T, Nagano C, Nozu K, Kamei K, Fujinaga S, Iijima K, et al. ; CNI in Monogenic SRNS Study Investigators
    • Journal Title

      Kidney International

      Volume: 103 Issue: 5 Pages: 962-972

    • DOI

      10.1016/j.kint.2023.02.022

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0147, KAKENHI-PROJECT-20H03698
  • [Journal Article] Clinical, Pathological, and Genetic Characteristics in Patients with Focal Segmental Glomerulosclerosis2022

    • Author(s)
      Nagano C, Hara S, Yoshikawa N, Takeda A, Gotoh Y, Hamada R, Matsuoka K, Yamamoto M, Fujinaga S, Sakuraya K, Kamei K, Hamasaki Y, Oguchi H, Araki Y, Ogawa Y, Okamoto T, Ito S, Tanaka S, Kaito H, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Horinouchi T, Yamamura T, Nagase H, Iijima K, Nozu K
    • Journal Title

      Kidney360

      Volume: 3 Issue: 8 Pages: 1384-1393

    • DOI

      10.34067/kid.0000812022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21KK0147, KAKENHI-PROJECT-20H03698
  • [Journal Article] FAT1 biallelic truncating mutation causes a non-syndromic proteinuria in a child.2021

    • Author(s)
      Rossanti R, Watanabe T, Nagano C, Hara S, Horinouchi T, Yamamura T, Sakakibara N, Ninchoji T, Iijima K, Nozu K.
    • Journal Title

      CEN Case Reports

      Volume: 10(1) Issue: 1 Pages: 100-105

    • DOI

      10.1007/s13730-020-00529-y

    • Open Access
    • Data Source
      KAKENHI-PROJECT-18KK0244
  • [Journal Article] Genotype-phenotype correlation in WT1 exon 8 to 9 missense variants2021

    • Author(s)
      China Nagano, Yutaka Takaoka, Koichi Kamei, Riku Hamada, Daisuke Ichikawa, Kazuki Tanaka, Yuya Aoto, Shinya Ishiko, Rini Rossanti, Nana Sakakibara, Eri Okada, Tomoko Horinouchi, Tomohiko Yamamura, Yurika Tsuji, Yuko Noguchi, Shingo Ishimori, Hiroaki Nagase, Takeshi Ninchoji, Kazumoto Iijima, Kandai Nozu
    • Journal Title

      Kidney International Reports

      Volume: - Issue: 8 Pages: 2114-2121

    • DOI

      10.1016/j.ekir.2021.05.009

    • NAID

      120007140164

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16926, KAKENHI-PROJECT-21K12110
  • [Journal Article] An extremely mild clinical course in a case with LAMB2-associated nephritis diagnosed with next-generation sequencing.2021

    • Author(s)
      Sakuraya K, Nozu K, Murakami H, Nagano C, Horinouchi T, Fujinaga S, Iijima K, Ohtomo Y.
    • Journal Title

      CEN Case Reports

      Volume: - Issue: 3 Pages: 359-363

    • DOI

      10.1007/s13730-021-00574-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KK0244, KAKENHI-PROJECT-19K08726
  • [Journal Article] Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome2020

    • Author(s)
      Jia Xiaoyuan、Yamamura Tomohiko、et al.
    • Journal Title

      Kidney International

      Volume: 98 Issue: 5 Pages: 1308-1322

    • DOI

      10.1016/j.kint.2020.05.029

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07799, KAKENHI-PROJECT-19K08726, KAKENHI-PROJECT-20K08370, KAKENHI-PROJECT-20K16892, KAKENHI-PROJECT-18KK0244, KAKENHI-PROJECT-20H03698
  • [Journal Article] Molecular mechanisms determining severity in patients with Pierson syndrome2020

    • Author(s)
      Minamikawa Shogo、Miwa Saori、Inagaki Tetsuji、Nishiyama Kei、Kaito Hiroshi、Ninchoji Takeshi、Yamamura Tomohiko、Nagano China、Sakakibara Nana、Ishimori Shingo、Hara Shigeo、Yoshikawa Norishige、Hirano Daishi、Harada Ryoko、Hamada Riku、Matsunoshita Natsuki、Nagata Michio、Shima Yuko、Nozu Kandai
    • Journal Title

      Journal of Human Genetics

      Volume: 65 Issue: 4 Pages: 355-362

    • DOI

      10.1038/s10038-019-0715-0

    • NAID

      120006811107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08726, KAKENHI-PROJECT-17K16087, KAKENHI-PROJECT-18K07799, KAKENHI-PROJECT-18K08243, KAKENHI-PROJECT-19K17297, KAKENHI-PROJECT-18KK0244
  • [Journal Article] Comprehensive genetic diagnosis of Japanese patients with severe proteinuria.2020

    • Author(s)
      Nagano C, Yamamura T, Horinouchi T, Aoto Y, Ishiko S, Sakakibara N, Shima Y, Nakanishi K, Nagase H, Iijima K, Nozu K.
    • Journal Title

      Sci Rep.

      Volume: 10(1) Issue: 1 Pages: 428-437

    • DOI

      10.1038/s41598-019-57149-5

    • NAID

      120006884200

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07799, KAKENHI-PROJECT-19K08726, KAKENHI-PROJECT-18KK0244, KAKENHI-PROJECT-18K15713
  • [Journal Article] Molecular assay for an intronic variant in NUP93 that causes steroid resistant nephrotic syndrome2019

    • Author(s)
      Rossanti Rini、Shono Akemi、Miura Kenichiro、Hattori Motoshi、Yamamura Tomohiko、Nakanishi Keita、Minamikawa Shogo、Fujimura Junya、Horinouchi Tomoko、Nagano China、Sakakibara Nana、Kaito Hiroshi、Nagase Hiroaki、Morisada Naoya、Asanuma Katsuhiko、Matsuo Masafumi、Nozu Kandai、Iijima Kazumoto
    • Journal Title

      Journal of Human Genetics

      Volume: 64 Issue: 7 Pages: 673-679

    • DOI

      10.1038/s10038-019-0606-4

    • NAID

      120006653286

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08243, KAKENHI-PROJECT-19K09921, KAKENHI-PROJECT-18KK0244, KAKENHI-PROJECT-18K15712, KAKENHI-PROJECT-18H02823
  • [Journal Article] The utility of urinary CD80 as a diagnostic marker in patients with renal diseases2018

    • Author(s)
      Minamikawa Shogo、Nozu Kandai、Maeta Shingo、Yamamura Tomohiko、Nakanishi Keita、Fujimura Junya、Horinouchi Tomoko、Nagano China、Sakakibara Nana、Nagase Hiroaki、Shima Hideaki、Noda Kenta、Ninchoji Takeshi、Kaito Hiroshi、Iijima Kazumoto
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 17322-17322

    • DOI

      10.1038/s41598-018-35798-2

    • NAID

      120006543320

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KK0244
  • [Journal Article] Pair analysis and custom array CGH can detect a small copy number variation in COQ6 gene2018

    • Author(s)
      Nakanishi Keita、Okamoto Takayuki、Nozu Kandai、Hara Shigeo、Sato Yasuyuki、Hayashi Asako、Takahashi Toshiyuki、Nagano China、Sakakibara Nana、Horinouchi Tomoko、Fujimura Junya、Minamikawa Shogo、Yamamura Tomohiko、Rossanti Rini、Nagase Hiroaki、Kaito Hiroshi、Ariga Tadashi、Iijima Kazumoto
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 23 Issue: 5 Pages: 669-675

    • DOI

      10.1007/s10157-018-1682-z

    • NAID

      120006644119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18KK0244, KAKENHI-PROJECT-17K16262, KAKENHI-PROJECT-18K15712
  • [Presentation] WT1遺伝子exon8-9ミスセンス変異における遺伝子型-臨床型の相関に関する検討2020

    • Author(s)
      長野 智那
    • Organizer
      第63回 日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K16926
  • [Presentation] WT1遺伝子exon8-9ミスセンス変異における遺伝型-臨床型の相関に関する研究2020

    • Author(s)
      長野 智那
    • Organizer
      第55回 日本小児腎臓病学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K16926
  • [Presentation] NPHS1は小児ステロイド感受性ネフローゼ症候群の疾患感受性遺伝子である2019

    • Author(s)
      山村智彦、長野智那、堀之内智子、 野津寛大、飯島一誠
    • Organizer
      第62回日本腎臓学会学術集会
    • Data Source
      KAKENHI-PROJECT-18KK0244
  • [Presentation] 遺伝性ネフローゼ症候群における臨床的特徴の検討2019

    • Author(s)
      長野 智那
    • Organizer
      第54回日本小児腎臓病学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K15713
  • [Presentation] Comprehensive genetic diagnosis system for steroid-resistant nephrotic syndrome in Japanese population2019

    • Author(s)
      長野 智那
    • Organizer
      International Pediartic Nephrology Association 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15713
  • [Presentation] 先天性/乳児および ステロイド抵抗性ネフローゼ症候群における網羅的遺伝子診断2019

    • Author(s)
      長野智那、野津寛大、青砥悠哉、石河慎也、榊原菜々、南川将吾、山村智彦、飯島一誠
    • Organizer
      第122回日本小児科学会学術集会
    • Data Source
      KAKENHI-PROJECT-18KK0244
  • [Presentation] Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome2019

    • Author(s)
      Tomoko Horinouchi, Tomohiko Yamamura, Rasheed A. Gbadegesin, Matthew G. Sampson, China Nagano, Kandai Nozu, Kenji Ishikura, Pierre M. Ronco, Hae Il Cheong, Kazumoto Iijima
    • Organizer
      American Society of Nephrology Kidney week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0244
  • [Presentation] 遺伝性ネフローゼ症候群における臨床的特徴の検討2019

    • Author(s)
      長野智那、野津寛大、青砥悠哉、石河慎也、榊原菜々、南川将吾、山村智彦、飯島一誠
    • Organizer
      第54回日本小児腎臓病学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18KK0244
  • [Presentation] 遺伝性ネフローゼ症候群における臨床的特徴の検討2019

    • Author(s)
      長野 智那
    • Organizer
      第62回日本腎臓学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K15713
  • [Presentation] 遺伝性腎疾患に対するプレシジョンメデイスン 小児ステロイド感受性ネフローゼ症候群の疾患感受性遺伝子2019

    • Author(s)
      飯島一誠、 Jia Xiaoyuan,、山村智彦、人見祐基、長野智那、堀之内智子、野津寛大、徳永勝士
    • Organizer
      第54回日本小児腎臓病学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18KK0244
  • 1.  IIJIMA KAZUMOTO (00240854)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 13 results
  • 2.  堀之内 智子 (30754593)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 12 results
  • 3.  野津 寛大 (70362796)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 4.  人見 祐基 (10525819)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  高里 実 (40788676)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  賈 暁媛 (20914328)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  中山 真紀子 (80469999)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MORISADA Naoya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  NAKANISHI Koichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  SHIMA Yuko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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