SAKURA Takaya 佐倉孝哉

Researcher Number	60816726
Other IDs
Affiliation (Current)	2025: 長崎大学, 熱帯医学研究所, 助教
Affiliation (based on the past Project Information) *help	2025: 長崎大学, 熱帯医学研究所, 助教 2019 – 2023: 長崎大学, 熱帯医学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 49040:Parasitology-related / Transformative Research Areas, Section (III) / Basic Section 50010:Tumor biology-related Except Principal Investigator Medium-sized Section 49:Pathology, infection/immunology, and related fields
Keywords	Principal Investigator エネルギー代謝 / 解糖系 / マラリア原虫 / LLPS / 酵素集合体 / ゲノム編集 / ミトコンドリア / 薬剤耐性 / マラリア / 液-液相分離 … More / 細胞内相分離 / ガメトサイト / ピリミジン生合成経路 / がん微小環境 / フマル酸呼吸 / ジヒドロオロト酸脱水素酵素 / ピリミジン生合成 … More Except Principal Investigator メロゾイト / マラリア原虫 / 滑走運動 / 赤血球侵入 / マラリア / 熱帯熱マラリア原虫 Less

マラリア原虫ミトコンドリアゲノム編集による呼吸鎖阻害剤耐性機構の解明Principal Investigator
- Principal Investigator
  
  佐倉孝哉
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Nagasaki University
マラリア原虫赤内期の解糖系制御機構の解明Principal Investigator
- Principal Investigator
  
  佐倉孝哉
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Nagasaki University
マラリア原虫ガメトサイト分化に伴うエネルギー代謝変化Principal Investigator
- Principal Investigator
  
  佐倉孝哉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Nagasaki University
Molecular mechanisms of gliding motility in Plasmodium merozoites
- Principal Investigator
  
  矢幡一英
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Ehime University
De novo biosynthesis of pyrimidine in tumor microenvironment.Principal Investigator
- Principal Investigator
  
  SAKURA Takaya
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Nagasaki University
Molecular mechanisms of gliding motility and erythrocyte invasion by Plasmodium falciparum
- Principal Investigator
  
  YAHATA KAZUHIDE
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Ehime University
  Nagasaki University

All 2024 2023 2022 2020

All Journal Article Presentation

[Journal Article] Biochemical characterization and identification of ferulenol and embelin as potent inhibitors of malate:quinone oxidoreductase from Campylobacter jejuni2023
- Author(s)
  Kabongo Augustin Tshibaka、Acharjee Rajib、Sakura Takaya、Bundutidi Gloria Mavinga、Hartuti Endah Dwi、Davies Cadi、Gundogdu Ozan、Kita Kiyoshi、Shiba Tomoo、Inaoka Daniel Ken
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 10 Pages: 1095026-1095026
- DOI
  10.3389/fmolb.2023.1095026
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07045, KAKENHI-PROJECT-20H00620
[Journal Article] Effect of geranylated dihydrochalcone from Artocarpus altilis leaves extract on Plasmodium falciparum ultrastructural changes and mitochondrial malate: Quinone oxidoreductase2023
- Author(s)
  Hidayati Agriana Rosmalina、Melinda、Ilmi Hilkatul、Sakura Takaya、Sakaguchi Miako、Ohmori Junko、Hartuti Endah Dwi、Tumewu Lidya、Inaoka Daniel Ken、Tanjung Mulyadi、Yoshida Eri、Tokumasu Fuyuki、Kita Kiyoshi、Mori Mihoko、Dobashi Kazuyuki、Nozaki Tomoyoshi、Syafruddin Din et al.
- Journal Title
  
  International Journal for Parasitology: Drugs and Drug Resistance
  
  Volume: 21 Pages: 40-50
- DOI
  10.1016/j.ijpddr.2022.12.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07045, KAKENHI-PROJECT-22K07043
[Journal Article] Killing Two Birds with One Stone: Discovery of Dual Inhibitors of Oxygen and Fumarate Respiration in Zoonotic Parasite, Echinococcus multilocularis2023
- Author(s)
  Enkai Shigehiro、Kouguchi Hirokazu、Inaoka Daniel Ken、Shiba Tomoo、Hidaka Masahito、Matsuyama Hiroyuki、Sakura Takaya、Yagi Kinpei、Kita Kiyoshi
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 67 Issue: 3
- DOI
  10.1128/aac.01428-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07045, KAKENHI-PROJECT-22K07048
[Journal Article] Siccanin is a dual-target inhibitor of Plasmodium falciparum mitochondrial complex II and complex III.2022
- Author(s)
  Komatsuya K, Sakura T, Shiomi K, Omura S, Hikosaka K, Nozaki T, Kita K, Inaoka DK.
- Journal Title
  
  Pharmaceuticals
  
  Volume: 15 Issue: 7 Pages: 903-903
- DOI
  10.3390/ph15070903
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-22K07045, KAKENHI-PROJECT-20K07461
[Journal Article] 5-Aminolevulinic acid antiviral efficacy against SARS-CoV-2 omicron variant in vitro2022
- Author(s)
  Ngwe Tun Mya Myat、Sakura Takaya、Sakurai Yasuteru、Kurosaki Yohei、Inaoka Daniel Ken、Shioda Norifumi、Smith Chris、Yasuda Jiro、Morita Kouichi、Kita Kiyoshi
- Journal Title
  
  Tropical Medicine and Health
  
  Volume: 50 Issue: 1 Pages: 6-6
- DOI
  10.1186/s41182-022-00422-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07045, KAKENHI-PROJECT-22K19297, KAKENHI-PROJECT-20H03393, KAKENHI-PUBLICLY-21H00207
[Journal Article] Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target2020
- Author(s)
  Sato D, Hartuti ED, Inaoka DK, Sakura T, Amalia E, Nagahama M, Yoshioka Y, Tsuji N, Nozaki T, Kita K, Harada S, Matsubayashi M, Shiba T.
- Journal Title
  
  Genes (Basel)
  
  Volume: 11(12) Issue: 12 Pages: 1468-1468
- DOI
  10.3390/genes11121468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07523, KAKENHI-PROJECT-19K16719
[Presentation] マラリア原虫赤内期の解糖系酵素の動態解析2024
- Author(s)
  石井隆太、佐倉孝哉、稲岡健ダニエル、徳舛富由樹
- Organizer
  第93回寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] In silico prediction of guanine quadruplex sequences in Leishmania genome2024
- Author(s)
  Jing Hong, Takaya Sakura, Hirotaka Matsumoto, Fuyuki Tokumasu, Kiyoshi Kita, Inaoka Ken Daniel
- Organizer
  第93回寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] Analysis of liquid-liquid phase separation in Plasmodium falciparum2024
- Author(s)
  Ryuta Ishii, Takaya Sakura, Daniel Ken Inaoka, Fuyuki Tokumasu
- Organizer
  Molecular Approaches to Malaria 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] 新しいハイスループットスクリーニング法による速効性抗マラリア活性化合物探索系の構築2024
- Author(s)
  佐倉孝哉、石井隆太、吉田衣里、北潔、加藤輝久、稲岡健ダニエル
- Organizer
  第93回寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] リゾリン脂質アシル転移酵素（PfLPLAT1）は赤内期熱帯熱マラリア原虫（P. falciparum）の細胞周期進行とサイトストーム細胞内移行に必須である2024
- Author(s)
  福本隼平、吉田益奈子、徳岡涼美、早川枝季、宮崎真也、佐倉孝哉、稲岡健ダニエル、北潔、臼倉治郎、進藤英雄、徳舛富由樹
- Organizer
  第93回寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] The involvement of lipid droplets in regulation of type I interferon signaling in Plasmodium falciparum infected hepatocytes2023
- Author(s)
  Jing Hong、石井隆太、佐倉孝哉、徳舛富由樹、稲岡健ダニエル
- Organizer
  第29回分子寄生虫学ワークショップ第19回分子寄生虫・マラリア研究フォーラム合同大会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] マラリア原虫ガメトサイト分化に伴うエネルギー代謝変化2023
- Author(s)
  佐倉孝哉、石井隆太、徳舛富由樹、北潔、稲岡健ダニエル
- Organizer
  第29回分子寄生虫学ワークショップ第19回分子寄生虫・マラリア研究フォーラム合同大会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] Phenotypic screening of marine microbial extracts identifies an antimalarial compound targeting Plasmodium mitochondrial electron transport chain2023
- Author(s)
  Normalita Eka Pravitasari, Takaya Sakura, Kibet Ng’etich Japheth, Jun Takouda, Shusaku Mizukami, Kenji Hirayama, Kohsuke Takeda, Yoshimasa Tanaka, Kiyoshi Kita, Daniel Ken Inaoka
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] 長崎大学海洋微生物抽出物ライブラリーから単離されたマラリア原虫呼吸鎖阻害剤の作用メカニズム2023
- Author(s)
  Normalita Eka Pravitasari、佐倉孝哉、Kibet Ng’etich Japheth、竹生田淳、水上修作、平山謙二、武田弘資、田中義正、北潔、稲岡健ダニエル
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] Phenotypic screening of marine microbial extracts identified an antimalarial compound targeting mitochondrial electron transport chain2023
- Author(s)
  Normalita Eka Pravitasari, Takaya Sakura, Kibet Ng’etich Japheth, Jun Takouda, Shusaku Mizukami, Kenji Hirayama, Kohsuke Takeda, Yoshimasa Tanaka, Kiyoshi Kita, Daniel Ken Inaoka
- Organizer
  ミトコンドリア・サイエンス・ワークショップ (MSW2023)
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] Phenotypic screening of marine microbial extracts identified an antimalarial compound targeting mitochondrial electron transport chain2023
- Author(s)
  Normalita Eka Pravitasari, Takaya Sakura, Kibet Ng’etich Japheth, Jun Takouda, Shusaku Mizukami, Kenji Hirayama, Kohsuke Takeda, Yoshimasa Tanaka, Kiyoshi Kita, Daniel Ken Inaoka
- Organizer
  第21回松山国際学術シンポジウム・PRiME 共同研究発表会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] Validation of a molecular-docking method Against Alphafold-predicted Targets for Antimalarial Drug Discovery2023
- Author(s)
  Ng’etich Japheth Kibet, Normalita Eka Pravitasari, Takeshi Ishikawa, Ayato Sato, Noriyuki Nishida, Takaya Sakura, Daniel Ken Inaoka
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] Nitroreductaseと蛍光プローブを用いた新規マラリア原虫High-throughput screening系の確立2023
- Author(s)
  佐倉孝哉、石井隆太、吉田衣里、高谷健二、北潔、加藤輝久、稲岡健ダニエル
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] P. falciparumにおける細胞内液ー液相分離の解析2023
- Author(s)
  石井隆太、佐倉孝哉、稲岡健ダニエル、徳舛富由樹
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] シッカニンによるマラリア原虫複合体II/III阻害活性の評価2022
- Author(s)
  小松谷啓介、佐倉孝哉、塩見和朗、大村智、彦坂健児、野崎智義、北潔、稲岡健ダニエル
- Organizer
  日本生体エネルギー研究会第48回討論会
- Data Source
  KAKENHI-PROJECT-22K07045
[Presentation] Ascofuranone suppresses cancer cells growth under microenvironment conditions through blockage of the de novo pyrimidine biosynthesis pathway2020
- Author(s)
  Mohammed S. O. Tagod, Takaya Sakura, Yukiko Miyazaki, Daniel Ken Inaoka, Kiyoshi Kita
- Organizer
  日本生体エネルギー研究会
- Data Source
  KAKENHI-PROJECT-19K16719
[Presentation] Identification of new antimalarial drug candidate that inhibit Plasmodium falciparum mitochondrial dihydroorotate dehydrogenase2020
- Author(s)
  Hartuti Endah D, Sakura Takaya, Wang Xinying, Mochizuki Kota, Acharjee Rajib, Matsuo Yuichi, Mori Mihoko, Shiomi Kazuro, Nozaki Tomoyoshi, Hamano Shinjiro, Kita Kiyoshi, Inaoka Daniel Ken
- Organizer
  日本寄生虫学会
- Data Source
  KAKENHI-PROJECT-19K16719

1. YAHATA KAZUHIDE (40467965)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. アサレクワメ・クミ (70854222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 山中聡士 (50853884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 彦坂健児

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 稲岡健ダニエル

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKURA Takaya 佐倉 孝哉

Research Projects

Research Products

Co-Researchers

マラリア原虫ミトコンドリアゲノム編集による呼吸鎖阻害剤耐性機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マラリア原虫赤内期の解糖系制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マラリア原虫ガメトサイト分化に伴うエネルギー代謝変化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of gliding motility in Plasmodium merozoites

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

De novo biosynthesis of pyrimidine in tumor microenvironment.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of gliding motility and erythrocyte invasion by Plasmodium falciparum

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Biochemical characterization and identification of ferulenol and embelin as potent inhibitors of malate:quinone oxidoreductase from Campylobacter jejuni2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of geranylated dihydrochalcone from Artocarpus altilis leaves extract on Plasmodium falciparum ultrastructural changes and mitochondrial malate: Quinone oxidoreductase2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Killing Two Birds with One Stone: Discovery of Dual Inhibitors of Oxygen and Fumarate Respiration in Zoonotic Parasite, Echinococcus multilocularis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Siccanin is a dual-target inhibitor of Plasmodium falciparum mitochondrial complex II and complex III.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 5-Aminolevulinic acid antiviral efficacy against SARS-CoV-2 omicron variant in vitro2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] マラリア原虫赤内期の解糖系酵素の動態解析2024

Author(s)

Organizer

Data Source

[Presentation] In silico prediction of guanine quadruplex sequences in Leishmania genome2024

Author(s)

Organizer

Data Source

[Presentation] Analysis of liquid-liquid phase separation in Plasmodium falciparum2024

Author(s)

SAKURA Takaya 佐倉孝哉