Watanabe Takashi 渡邉昂

Researcher Number	60817071
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 川崎医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 56030:Urology-related
Keywords	Principal Investigator サイコシン / スフィンゴ脂質 / ガラクトシルセラミド / クラッベ病 / ラクトシルセラミド / Krabbe病 / ミクログリア / マクロファージ / サイコシン仮説 Except Principal Investigator 細胞極性 … More / 移行上皮細胞 / 膀胱 / フィトセラミド / セラミド骨格 / スフィンゴ糖脂質 / 膀胱移行上皮 Less

クラッベ病の病態を悪化させるメカニズムの探索Principal Investigator
- Principal Investigator
  
  渡邉昂
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kawasaki Medical School
Structural diversity of ceramide moiety responsible for apical membrane function of bladder transitional epithelial cells
- Principal Investigator
  
  松田純子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kawasaki Medical School
Proposal of a new mechanism of Krabbe disease to replace the 'psychosine hypothesis'Principal Investigator
- Principal Investigator
  
  Watanabe Takashi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kawasaki Medical School

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] Mass Spectrometry of Neutral Glycosphingolipids2023
- Author(s)
  Suzuki Akemi、Silsirivanit Atit、Watanabe Takashi、Matsuda Junko、Inamori Kei-ichiro、Inokuchi Jin-ichi
- Journal Title
  
  Methods in molecular biology
  
  Volume: 2613 Pages: 127-144
- DOI
  10.1007/978-1-0716-2910-9_11
- ISBN
  9781071629093, 9781071629109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15892, KAKENHI-PROJECT-23K08792, KAKENHI-PROJECT-20H03452
[Journal Article] Genetic ablation of Saposin-D in Krabbe disease eliminates psychosine accumulation but does not significantly improve demyelination2023
- Author(s)
  Takashi Watanabe, Kazuhito Tsuboi, Nobuaki Matsuda, Yuta Ishizuka, Shinji Go, Etsuko Watanabe, Ayaka Ono, Yasuo Okamoto, Junko Matsuda
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 166 Issue: 4 Pages: 720-746
- DOI
  10.1111/jnc.15876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08295, KAKENHI-PROJECT-23K07323, KAKENHI-PROJECT-23K08792, KAKENHI-PROJECT-23K10973
[Journal Article] Assays and Utilization of Enzymes Involved in Glycolipid Metabolism in Bacteria and Fungi2023
- Author(s)
  Ito Makoto、Ishibashi Yohei、Watanabe Takashi、Iwaki Jun、Kurita Toyohisa、Okino Nozomu
- Journal Title
  
  Methods in molecular biology
  
  Volume: 2613 Pages: 229-256
- DOI
  10.1007/978-1-0716-2910-9_18
- ISBN
  9781071629093, 9781071629109
- Data Source
  KAKENHI-PROJECT-21K15892
[Journal Article] Characterization of thraustochytrid-specific sterol O-acyltransferase: modification of DGAT2-like enzyme to increase the sterol production in Aurantiochytrium limacinum mh01862023
- Author(s)
  Ishibashi Yohei、Sadamitsu Shohei、Fukahori Yoshitomo、Yamamoto Yuki、Tanogashira Rin、Watanabe Takashi、Hayashi Masahiro、Ito Makoto、Okino Nozomu
- Journal Title
  
  Applied and Environmental Microbiology
  
  Volume: 89 Issue: 11
- DOI
  10.1128/aem.01001-23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07323
[Journal Article] The Urinary Bladder is Rich in Glycosphingolipids Composed of Phytoceramides2022
- Author(s)
  Watanabe Takashi、Suzuki Akemi、Ohira Shin、Go Shinji、Ishizuka Yuta、Moriya Takuya、Miyaji Yoshiyuki、Nakatsuka Tota、Hirata Keita、Nagai Atsushi、Matsuda Junko
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 63 Issue: 12 Pages: 100303-100303
- DOI
  10.1016/j.jlr.2022.100303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06120, KAKENHI-PROJECT-21K15892
[Journal Article] Involvement of acid ceramidase in the degradation of bioactive N-acylethanolamines2021
- Author(s)
  Tsuboi Kazuhito、Tai Tatsuya、Yamashita Ryouhei、Ali Hanif、Watanabe Takashi、Uyama Toru、Okamoto Yoko、Kitakaze Keisuke、Takenouchi Yasuhiro、Go Shinji、Rahman Iffat Ara Sonia、Houchi Hitoshi、Tanaka Tamotsu、Okamoto Yasuo、Tokumura Akira、Matsuda Junko、Ueda Natsuo
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  
  Volume: 1866 Issue: 9 Pages: 158972-158972
- DOI
  10.1016/j.bbalip.2021.158972
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07165, KAKENHI-PROJECT-19K07353, KAKENHI-PROJECT-19K08288, KAKENHI-PROJECT-19K08634, KAKENHI-PROJECT-19K11731, KAKENHI-PROJECT-20K19732, KAKENHI-PROJECT-18K06120, KAKENHI-PROJECT-20K11571, KAKENHI-PROJECT-21K15892
[Journal Article] Reduction in MIR-219 expression underlies cellular pathogenesis of oligodendrocytes in a mouse model of Krabbe disease.2021
- Author(s)
  Inamura N, Go S, Watanabe T, Takase H, Takakura N, Nakayama A, Takebayashi H, Matsuda J, Enokido Y.
- Journal Title
  
  Brain Pathology
  
  Volume: － Issue: 5 Pages: 12951-12951
- DOI
  10.1111/bpa.12951
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08288, KAKENHI-PROJECT-20K08248, KAKENHI-PROJECT-18K06120, KAKENHI-PROJECT-19K08313, KAKENHI-PROJECT-20K08224, KAKENHI-PROJECT-21K15892
[Presentation] 膀胱移行上皮には炭素数20のフィトセラミド構造が豊富に存在し構造維持に重要である．2023
- Author(s)
  渡邉昂、鈴木明身、大平伸、郷慎司、石塚佑太、森谷卓也、宮地禎幸、永井敦、松田純子．
- Organizer
  第64回日本生化学会中国・四国支部例会（松山）
- Data Source
  KAKENHI-PROJECT-23K08792
[Presentation] Krabbe病の神経病態はサイコシンの蓄積だけでは説明できない2023
- Author(s)
  松田純子, 渡邉　昂, 坪井一人, 郷　慎司, 石塚佑太
- Organizer
  第65回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-23K07323
[Presentation] 質量分析計を用いたKrabbe病モデルマウスのスフィンゴ脂質の定量解析2023
- Author(s)
  渡邉　昂, 石塚佑太, 松田純子
- Organizer
  第64回日本先天代謝異常学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07323
[Presentation] フィトセラミド構造は小腸上皮における脂質吸収に重要である．2023
- Author(s)
  渡邉昂、鈴木明身、石塚佑太、松田純子．
- Organizer
  第65回日本脂質生化学会（熊本）
- Data Source
  KAKENHI-PROJECT-23K08792
[Presentation] 膀胱上皮組織には炭素数20の長鎖塩基からなるフィトセラミド構造をもつスフィンゴ糖脂質が豊富に存在する．2023
- Author(s)
  松田純子、渡邉昂、鈴木明身、郷慎司、大平伸、森谷卓也．
- Organizer
  第65回日本生化学会（福岡）
- Data Source
  KAKENHI-PROJECT-23K08792
[Presentation] Pathophysiological analysis of Saposin D-deficient Twitcher mice2022
- Author(s)
  Takashi Watanabe, Shinji Go, Yuta Ishizuka, Kazuhito Tsuboi, Ayaka Ono, Junko Matsuda
- Organizer
  第63回日本先天代謝異常学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15892
[Presentation] クラッベ病の神経病態はサイコシンの蓄積だけでは説明できない2021
- Author(s)
  渡邉　昂, 坪井一人, 石塚佑太, 小野綾可, 郷　慎司, 松田純子
- Organizer
  第26回日本ライソゾーム研究会
- Data Source
  KAKENHI-PROJECT-21K15892
[Presentation] クラッベ病の神経病態は「サイコシン仮説」だけでは説明できない2021
- Author(s)
  渡邉　昂, 郷　慎司, 石塚佑太, 坪井一人, 小野綾可, 松田純子
- Organizer
  第62回　日本生化学会　中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-21K15892
[Presentation] Krabbe病の病態は「サイコシン仮説」のみでは説明できない2021
- Author(s)
  渡邉　昂, 郷　慎司, 坪井一人, 小野綾可, 松田純子
- Organizer
  第62回日本先天代謝異常学会　学術集会
- Data Source
  KAKENHI-PROJECT-21K15892

1. 松田純子 (60363149)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. HOUCHI Hajime

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 坪井一人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 竹之内康広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 岡本安雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 郷慎司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Watanabe Takashi 渡邉 昂

Research Projects

Research Products

Co-Researchers

クラッベ病の病態を悪化させるメカニズムの探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural diversity of ceramide moiety responsible for apical membrane function of bladder transitional epithelial cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Proposal of a new mechanism of Krabbe disease to replace the 'psychosine hypothesis'Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Mass Spectrometry of Neutral Glycosphingolipids2023

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Genetic ablation of Saposin-D in Krabbe disease eliminates psychosine accumulation but does not significantly improve demyelination2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Assays and Utilization of Enzymes Involved in Glycolipid Metabolism in Bacteria and Fungi2023

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Characterization of thraustochytrid-specific sterol O-acyltransferase: modification of DGAT2-like enzyme to increase the sterol production in Aurantiochytrium limacinum mh01862023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Urinary Bladder is Rich in Glycosphingolipids Composed of Phytoceramides2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of acid ceramidase in the degradation of bioactive N-acylethanolamines2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reduction in MIR-219 expression underlies cellular pathogenesis of oligodendrocytes in a mouse model of Krabbe disease.2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 膀胱移行上皮には炭素数20のフィトセラミド構造が豊富に存在し構造維持に重要である．2023

Author(s)

Organizer

Data Source

[Presentation] Krabbe病の神経病態はサイコシンの蓄積だけでは説明できない2023

Author(s)

Organizer

Data Source

[Presentation] 質量分析計を用いたKrabbe病モデルマウスのスフィンゴ脂質の定量解析2023

Author(s)

Organizer

Data Source

[Presentation] フィトセラミド構造は小腸上皮における脂質吸収に重要である．2023

Author(s)

Organizer

Data Source

[Presentation] 膀胱上皮組織には炭素数20の長鎖塩基からなるフィトセラミド構造をもつスフィンゴ糖脂質が豊富に存在する．2023

Author(s)

Organizer

Data Source

[Presentation] Pathophysiological analysis of Saposin D-deficient Twitcher mice2022

Watanabe Takashi 渡邉昂