Lucena-Cacace Antonio Ｌｕｃｅｎａ．ＣａｃａｃｅＡｎｔｏｎｉｏ

Researcher Number	60832748
Other IDs
Affiliation (Current)	2026: 大阪大学, ヒューマン・メタバース疾患研究拠点, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help	2024: 大阪大学, ヒューマン・メタバース疾患研究拠点, 特任准教授(常勤) 2022 – 2023: 京都大学, iPS細胞研究所, 特命助教 2020 – 2022: 京都大学, iPS細胞研究所, 特定研究員
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator hiPSC-EPI / stem cells / tissue bioengineering / epicardium / heart / Cell Cycle / pluripotent / CDKN1A / aging / WT1 … More / cardiac regeneration / cell cycle / regeneration / p21 / hiPSCs / Cardiology / Regeneration / Reprogramming / hiPSC-CMs / Heart / nanomedic / cellular bioengineering / disease modeling / eht / small molecules / tnni3 / cardiac maturation / Stem Cell Research / hiPSC-CM / TNNI3 / Cardiac maturation Less

Improving Functional Regeneration and Engraftment of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells by Brief Cycles of Transient ReprogrammingPrincipal Investigator
- Principal Investigator
  
  Lucena.Cacace Antonio
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Generation of highly regenerative human induced pluripotent stem cell-derived epicardial cells for cardiac repair and regenerationPrincipal Investigator
- Principal Investigator
  
  LUCENA-CACACE Antonio
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
  Kyoto University
Human induced pluripotent stem cell derived cardiomyocyte maturation by DNA integrative free-delivery of key regulatorsPrincipal Investigator
- Principal Investigator
  
  Lucena-Cacace Antonio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyoto University

All 2024 2023 2022 2020

All Journal Article Presentation Patent

[Journal Article] Generation of 3D-Multicellular Human iPSC-Heart Organoids for the Noninvasive Assessment of Cardiac Fibrosis2024
- Author(s)
  Lucena-Cacace A, Tian Y, Yoshida Y
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2803 Pages: 35-48
- DOI
  10.1007/978-1-0716-3846-0_3
- ISBN
  9781071638453, 9781071638460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04176, KAKENHI-PROJECT-22K16137
[Journal Article] Immunosuppressants Tacrolimus and Sirolimus revert the cardiac antifibrotic properties of p38-MAPK inhibition in 3D-multicellular human iPSC-heart organoids2022
- Author(s)
  Yu Tian, Yuta Tsujisaka, Vanessa Y Li, Kanae Tani, Antonio Lucena-Cacace, Yoshinori Yoshida
- Journal Title
  
  Front Cell Dev Biol
  
  Volume: 10
- DOI
  10.3389/fcell.2022.1001453
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17078
[Journal Article] CDH18 is a fetal epicardial biomarker regulating differentiation towards vascular smooth muscle cells2022
- Author(s)
  Julia Junghof, Yuta Kogure, Tian Yu, Eva Maria Verdugo-Sivianes, Megumi Narita, Antonio Lucena-Cacace, Yoshinori Yoshida
- Journal Title
  
  NPJ Regenerative Medicine
  
  Volume: 7 Issue: 1
- DOI
  10.1038/s41536-022-00207-w
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17078
[Journal Article] Analysis of Transcriptional Profiling of Chamber-Specific Human Cardiac Myocytes Derived from Pluripotent Stem Cells2022
- Author(s)
  Antonio Lucena-Cacace, Yoshinori Yoshida
- Journal Title
  
  Methods Mol Biol
  
  Volume: 2320 Pages: 219-232
- DOI
  10.1007/978-1-0716-1484-6_20
- ISBN
  9781071614839, 9781071614846
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17078
[Patent] 心外膜細胞再生促進剤および心外膜細胞の再生促進方法2023
- Inventor(s)
  ルセナカカセアントニオ, 吉田善紀, 田雨
- Industrial Property Rights Holder
  ルセナカカセアントニオ, 吉田善紀, 田雨
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-22K16137
[Patent] 心外膜細胞再生促進剤および心外膜細胞の再生促進方法2023
- Inventor(s)
  吉田善紀, ルセナカカセアントニオ
- Industrial Property Rights Holder
  吉田善紀, ルセナカカセアントニオ
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Acquisition Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-22K16137
[Patent] Mature-cardiomyocyte production method2020
- Inventor(s)
  Antonio Lucena-Cacace, etc
- Industrial Property Rights Holder
  Antonio Lucena-Cacace, etc
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Acquisition Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20K17078
[Presentation] Maturation of human iPSC-derived cardiomyocytes2022
- Author(s)
  Antonio Lucena-Cacace
- Organizer
  Leducq Network: Towards Precision Medicine with Human iPSCs for Cardiac Channelopathies (Stanford University, USA)
- Invited
- Data Source
  KAKENHI-PROJECT-20K17078

1. YOSHIDA Yoshinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Lucena-Cacace Antonio Ｌｕｃｅｎａ．Ｃａｃａｃｅ Ａｎｔｏｎｉｏ

Research Projects

Research Products

Co-Researchers

Improving Functional Regeneration and Engraftment of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells by Brief Cycles of Transient ReprogrammingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation of highly regenerative human induced pluripotent stem cell-derived epicardial cells for cardiac repair and regenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Human induced pluripotent stem cell derived cardiomyocyte maturation by DNA integrative free-delivery of key regulatorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Generation of 3D-Multicellular Human iPSC-Heart Organoids for the Noninvasive Assessment of Cardiac Fibrosis2024

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Immunosuppressants Tacrolimus and Sirolimus revert the cardiac antifibrotic properties of p38-MAPK inhibition in 3D-multicellular human iPSC-heart organoids2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CDH18 is a fetal epicardial biomarker regulating differentiation towards vascular smooth muscle cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of Transcriptional Profiling of Chamber-Specific Human Cardiac Myocytes Derived from Pluripotent Stem Cells2022

Author(s)

Journal Title

DOI

ISBN

Data Source

[Patent] 心外膜細胞再生促進剤および心外膜細胞の再生促進方法2023

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] 心外膜細胞再生促進剤および心外膜細胞の再生促進方 法2023

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Acquisition Date

Data Source

[Patent] Mature-cardiomyocyte production method2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Acquisition Date

Data Source

[Presentation] Maturation of human iPSC-derived cardiomyocytes2022

Author(s)

Organizer

Data Source

Lucena-Cacace Antonio Ｌｕｃｅｎａ．ＣａｃａｃｅＡｎｔｏｎｉｏ

[Patent] 心外膜細胞再生促進剤および心外膜細胞の再生促進方法2023