Mori Daisuke 森大典

Researcher Number	60835354
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 届出研究員
Affiliation (based on the past Project Information) *help	2024: 東京大学, 医学部附属病院, 届出研究員 2020 – 2022: 東京大学, 医学部附属病院, 届出研究員 2019 – 2020: 東京大学, 医学部附属病院, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator 関節炎 / 血友病 / 変形性関節症 / 関節軟骨 / HIF-2α / HIF-1α / 酸素濃度勾配 / 変形性膝関節症 / 整形外科学 Except Principal Investigator 整形外科学 … More / 変形性関節症 / シングルセル解析 / 軟骨 / 滑膜 / 関節恒常性 / 幹細胞治療 / 異種混合細胞RNAシークエンス / 生体投与後における間葉系幹細胞の変化 / 脂肪由来幹細胞投与後の局在 / マウス神経障害性疼痛モデル / 神経根症 / 脂肪由来幹細胞 / 間葉系幹細胞 / 細胞製剤 / 分化誘導条件 / 細胞製剤の開発 / ヒトES細胞 / 変形性膝関節症 / 骨軟骨代謝学 / 滑膜組織 / 関節軟骨 / 線維芽細胞 / マクロファージ / 廃用症候群 / 関節運動 Less

血液凝固異常時の炎症に起因する関節症発症メカニズムの解明Principal Investigator
- Principal Investigator
  
  森大典
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Molecular mechanisms underlying homeostasis of artiuclar joint
- Principal Investigator
  
  Saito Taku
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Research of cells involved in radiculopathy and development of its treatment using mesenchymal stem cells
- Principal Investigator
  
  Matsubayashi Yoshitaka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Elucidation of articular joint homeostasis regulated by the cellular network in the synovium
- Principal Investigator
  
  Tanaka Sakae
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Molecular mechanisms underlying homeostasis of artiuclar joint by oxygen and two HIFsPrincipal Investigator
- Principal Investigator
  
  Mori Daisuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Development of induced Drug-Cells for treating Arthritis (DCA) using human ES cells for osteoarthritis
- Principal Investigator
  
  Saito Taku
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo

All 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Automatic Detection of Medial and Lateral Compartments from Histological Sections of Mouse Knee Joints Using the Single-Shot Multibox Detector Algorithm2022
- Author(s)
  Mori Yoshifumi、Oichi Takeshi、Enomoto-Iwamoto Motomi、Saito Taku
- Journal Title
  
  CARTILAGE
  
  Volume: 13 Issue: 1
- DOI
  10.1177/19476035221074009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-19K18540, KAKENHI-PROJECT-20K09495, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-20H03799
[Journal Article] TRPV2 is involved in induction of lubricin and suppression of ectopic endochondral ossification in articular joints2021
- Author(s)
  Nakamoto Hideki、Katanosaka Yuki、Chijimatsu Ryota、Mori Daisuke、Xuan Fengjun、Yano Fumiko、Omata Yasunori、Maenohara Yuji、Murahashi Yasutaka、Kawaguchi Kohei、Yamagami Ryota、Inui Hiroshi、Taketomi Shuji、Taniguchi Yuki、Kanagawa Motoi、Naruse Keiji、Tanaka Sakae、Saito Taku
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: - Issue: 8 Pages: 1441-1450
- DOI
  10.1002/art.41684
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-21H04960, KAKENHI-PROJECT-20H03799, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-21K09294, KAKENHI-PROJECT-20K20644, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-18K09019
[Journal Article] Regulation of osteoarthritis development by ADAM17/Tace in articular cartilage2021
- Author(s)
  Kaneko Taizo、Horiuchi Keisuke、Chijimatsu Ryota、Mori Daisuke、Nagata Kosei、Omata Yasunori、Yano Fumiko、Inui Hiroshi、Moro Toru、Tanaka Sakae、Saito Taku
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: 40 Issue: 2 Pages: 196-207
- DOI
  10.1007/s00774-021-01278-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08246, KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-20H03799, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K09495, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-21K20942
[Journal Article] Ear Cartilage Reconstruction Combining Induced Pluripotent Stem Cell-Derived Cartilage and Three-Dimensional Shape-Memory Scaffold2020
- Author(s)
  Uto Sakura、Hikita Atsuhiko、Sakamoto Tomoaki、Mori Daisuke、Yano Fumiko、Ohba Shinsuke、Saito Taku、Takato Tsuyoshi、Hoshi Kazuto
- Journal Title
  
  Tissue Engineering Part A
  
  Volume: - Issue: 9-10 Pages: 604-617
- DOI
  10.1089/ten.tea.2020.0106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-18K19635, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-18K09019, KAKENHI-PROJECT-23K21494
[Journal Article] Lubricin Contributes to Homeostasis of Articular Cartilage by Modulating Differentiation of Superficial Zone Cells2020
- Author(s)
  Maenohara Yuji、Chijimatsu Ryota、Tachibana Naohiro、Uehara Kosuke、Xuan Fengjun、Mori Daisuke、Murahashi Yasutaka、Nakamoto Hideki、Oichi Takeshi、Chang Song Ho、Matsumoto Takumi、Omata Yasunori、Yano Fumiko、Tanaka Sakae、Saito Taku
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 36 Issue: 4 Pages: 792-802
- DOI
  10.1002/jbmr.4226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-18K09017, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-21K16690, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-18K09019
[Journal Article] Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling2020
- Author(s)
  Okada Keita、Mori Daisuke、Makii Yuma、Nakamoto Hideki、Murahashi Yasutaka、Yano Fumiko、Chang Song Ho、Taniguchi Yuki、Kobayashi Hiroshi、Semba Hiroaki、Takeda Norihiko、Piao Wen、Hanaoka Kenjiro、Nagano Tetsuo、Tanaka Sakae、Saito Taku
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 5425-5425
- DOI
  10.1038/s41598-020-62463-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-19K22677, KAKENHI-PUBLICLY-18H04609, KAKENHI-PUBLICLY-19H05414, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-18H02360, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10996, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-18K09017, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-20K09405
[Journal Article] Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds2019
- Author(s)
  Kawata Manabu、Mori Daisuke、Kanke Kosuke、Hojo Hironori、Ohba Shinsuke、Chung Ung-il、Yano Fumiko、Masaki Hideki、Otsu Makoto、Nakauchi Hiromitsu、Tanaka Sakae、Saito Taku
- Journal Title
  
  Stem Cell Reports
  
  Volume: 13 Issue: 3 Pages: 530-544
- DOI
  10.1016/j.stemcr.2019.07.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K19600, KAKENHI-PROJECT-18K16645, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone2019
- Author(s)
  Xuan Fengjun、Yano Fumiko、Mori Daisuke、Chijimatsu Ryota、Maenohara Yuji、Nakamoto Hideki、Mori Yoshifumi、Makii Yuma、Oichi Takeshi、Taketo Makoto Mark、Hojo Hironori、Ohba Shinsuke、Chung Ung-il、Tanaka Sakae、Saito Taku
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 21 Issue: 1 Pages: 247-247
- DOI
  10.1186/s13075-019-2041-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10996, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Presentation] ルブリシンは関節軟骨最表層細胞の分化を抑制し軟骨のホメオスタシスを維持している2019
- Author(s)
  前之原悠司、森大典、齋藤琢、他
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] メカノセンサーTrpv2 はLubricin の誘導を介して関節軟骨を保護する2019
- Author(s)
  中元秀樹、森大典、齋藤琢、他
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] Taceは変形性関節症を促進的に制御する2019
- Author(s)
  金子泰三、森大典、齋藤琢、他
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09568

1. Saito Taku (30456107)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
2. 岡田慶太 (50759173)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. Tanaka Sakae (50282661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Matsubayashi Yoshitaka (50747962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山神良太 (00722191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 千々松良太 (60803210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 河田学 (10803174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 矢野文子 (80529040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 大野久美子 (30444251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 寺島明日香 (30596937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小俣康徳 (40570734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Mori Daisuke 森 大典

Research Projects

Research Products

Co-Researchers

血液凝固異常時の炎症に起因する関節症発症メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms underlying homeostasis of artiuclar joint

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research of cells involved in radiculopathy and development of its treatment using mesenchymal stem cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of articular joint homeostasis regulated by the cellular network in the synovium

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms underlying homeostasis of artiuclar joint by oxygen and two HIFsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of induced Drug-Cells for treating Arthritis (DCA) using human ES cells for osteoarthritis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Automatic Detection of Medial and Lateral Compartments from Histological Sections of Mouse Knee Joints Using the Single-Shot Multibox Detector Algorithm2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TRPV2 is involved in induction of lubricin and suppression of ectopic endochondral ossification in articular joints2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of osteoarthritis development by ADAM17/Tace in articular cartilage2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ear Cartilage Reconstruction Combining Induced Pluripotent Stem Cell-Derived Cartilage and Three-Dimensional Shape-Memory Scaffold2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lubricin Contributes to Homeostasis of Articular Cartilage by Modulating Differentiation of Superficial Zone Cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone2019

Author(s)

Journal Title

DOI

Data Source

Mori Daisuke 森大典