LIM KEE SIANG ＬＩＭＫＥＥ・ＳＩＡＮＧ

… Alternative Names

Lim Kee Siang LIM KEE・SIANG

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Researcher Number	60842987
Other IDs
Affiliation (Current)	2026: 金沢大学, ナノ生命科学研究所, 特任助教
Affiliation (based on the past Project Information) *help	2019 – 2024: 金沢大学, ナノ生命科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / 0803:Pathology, infection/immunology, and related fields Except Principal Investigator Medium-sized Section 37:Biomolecular chemistry and related fields
Keywords	Principal Investigator High-speed AFM / viral fusion protein / Influenza A / SARS-CoV-2 / Hemagglutinin / HS-AFM / Nuclear transport / Nuclear pore complex / RNA viruses / RNA-N protein complex … More / RNA compaction / Nucleocapsid protein / Exosome / High Speed AFM / Virulence factor / Influenz A / Fusogenic transition / Virulence factors / Direct visualization / exosome / fusogenic transition / Viral fusion protein / Viral Fusion Protein / COVID-19 / Neutralizing antibodies / SARS-CoV-2 spike protein / HS-AFM nanoimaging / Spike protein / Viral fusion proteins … More Except Principal Investigator 相分離 / 翻訳後修飾 / 液－液相分離 / 核膜孔 / 核膜孔複合体 Less

Nanoscopic elucidation of dynamic behavior of RNA viral nucleocapsid proteins using high-speed atomic force microscopy (HS-AFM)Principal Investigator
- Principal Investigator
  
  LIM KEE・SIANG
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kanazawa University
Functional Dynamics of Liquid-Liquid Phase Separation Mediated by Nuclear Pore Complex
- Principal Investigator
  
  Wong Richard
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Kanazawa University
Real-time observation of native conformations and molecular behaviors of viral fusion proteins using high-speed atomic force microscopy (HS-AFM)Principal Investigator
- Principal Investigator
  
  Lim Kee Siang
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kanazawa University
Direct visualization of conformational dynamics of hemagglutinin and interaction between hemagglutinin and exosomes using high-speed atomic force microscopy.Principal Investigator
- Principal Investigator
  
  Lim Kee Siang
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0803:Pathology, infection/immunology, and related fields
- Research Institution
  Kanazawa University

All 2025 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Nanoscopic Profiling of Small Extracellular Vesicles via High‐Speed Atomic Force Microscopy (HS‐AFM) Videography2025
- Author(s)
  Sandira Muhammad Isman、Lim Keesiang、Yoshida Takeshi、Sajidah Elma Sakinatus、Narimatsu Shinnosuke、Imakawa Reon、Yoshimura Kota、Nishide Goro、Qiu Yujia、Taoka Azuma、Hazawa Masaharu、Ando Toshio、Hanayama Rikinari、Wong Richard W.
- Journal Title
  
  Journal of Extracellular Vesicles
  
  Volume: 14 Issue: 4 Pages: 1-12
- DOI
  10.1002/jev2.70050
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04278, KAKENHI-PUBLICLY-24H01276, KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-23K23476, KAKENHI-PROJECT-24K18449
[Journal Article] Strategies for the Viral Exploitation of Nuclear Pore Transport Pathways2025
- Author(s)
  Zhang Xin、Lim Keesiang、Qiu Yujia、Hazawa Masaharu、Wong Richard W.
- Journal Title
  
  Viruses
  
  Volume: 17 Issue: 2 Pages: 151-151
- DOI
  10.3390/v17020151
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K18449
[Journal Article] Zooming into Gene Activation: Estrogen Receptor α Dimerization and DNA Binding Visualized by High-Speed Atomic Force Microscopy2025
- Author(s)
  Nishide Goro、Ishibashi Tomoka、Lim Keesiang、Qiu Yujia、Hazawa Masaharu、Matsushima Ayami、Wong Richard W.
- Journal Title
  
  ACS Nano
  
  Volume: 19 Issue: 16 Pages: 15395-15410
- DOI
  10.1021/acsnano.4c14943
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04278, KAKENHI-PUBLICLY-24H01276, KAKENHI-PROJECT-23K23476, KAKENHI-PROJECT-24K18449
[Journal Article] Spatiotemporal dynamics of protamine-DNA condensation revealed by high-speed atomic force microscopy2025
- Author(s)
  Nishide G, Lim K, Kobayashi A, Qiu Y, Hazawa M, Ando T, Okada Y, Wong RW.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 53 Issue: 6 Pages: 1-11
- DOI
  10.1093/nar/gkaf152
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05939, KAKENHI-PUBLICLY-23H04278, KAKENHI-PUBLICLY-24H01276, KAKENHI-PROJECT-22K06924, KAKENHI-PROJECT-23K23476, KAKENHI-PROJECT-24K18449
[Journal Article] Phase-separated super-enhancers confer an innate radioresistance on genomic DNA2024
- Author(s)
  Matsumoto Koki、Ikliptikawati Dini Kurnia、Makiyama Kei、Mochizuki Kako、Tobita Maho、Kobayashi Isao、Voon Dominic Chih-Cheng、Lim Keesiang、Ogawa Kazuma、Kashiwakura Ikuo、Suzuki Hiroshi I、Yoshino Hironori、Wong Richard W、Hazawa Masaharu
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 65 Issue: 4 Pages: 482-490
- DOI
  10.1093/jrr/rrae044
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27544, KAKENHI-PROJECT-21K07691, KAKENHI-PROJECT-24K18449
[Journal Article] An Efficient Method for Isolating and Purifying Nuclei from Mice Brain for Single-Molecule Imaging Using High-Speed Atomic Force Microscopy2024
- Author(s)
  Qiu Yujia、Sajidah Elma Sakinatus、Kondo Sota、Narimatsu Shinnosuke、Sandira Muhammad Isman、Higashiguchi Yoshiki、Nishide Goro、Taoka Azuma、Hazawa Masaharu、Inaba Yuka、Inoue Hiroshiら
- Journal Title
  
  Cells
  
  Volume: 13 Issue: 3 Pages: 279-279
- DOI
  10.3390/cells13030279
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19545, KAKENHI-PUBLICLY-22H05537, KAKENHI-PUBLICLY-23H04278, KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-23K23476, KAKENHI-PROJECT-23K24764, KAKENHI-PROJECT-23K26816, KAKENHI-PROJECT-23K27996, KAKENHI-PROJECT-22H00484, KAKENHI-PROJECT-23H00521, KAKENHI-PROJECT-24K18449
[Journal Article] Crafty mimicry grants nuclear pore entry to HIV2024
- Author(s)
  Lim Keesiang、Hazawa Masaharu、Wong Richard W.
- Journal Title
  
  Cell Host & Microbe
  
  Volume: 32 Issue: 4 Pages: 441-442
- DOI
  10.1016/j.chom.2024.03.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16262, KAKENHI-PUBLICLY-22H05537, KAKENHI-PUBLICLY-23H04278, KAKENHI-PUBLICLY-24H01276, KAKENHI-PROJECT-23K23476, KAKENHI-PROJECT-24K18449
[Journal Article] Nanoimaging of SARS-CoV-2 viral invasion toward the nucleus and genome2024
- Author(s)
  Sajidah Elma Sakinatus、Lim Keesiang、Hazawa Masaharu、Wong Richard W.
- Journal Title
  
  Cell Reports Physical Science
  
  Volume: 5 Issue: 9 Pages: 102111-102111
- DOI
  10.1016/j.xcrp.2024.102111
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K18449
[Journal Article] Nanoscopic Elucidation of Spontaneous Self-Assembly of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Open Reading Frame 6 (ORF6) Protein2023
- Author(s)
  Nishide Goro、Lim Keesiang、Tamura Maiki、Kobayashi Akiko、Zhao Qingci、Hazawa Masaharu、Ando Toshio、Nishida Noritaka、Wong Richard W.
- Journal Title
  
  The Journal of Physical Chemistry Letters
  
  Volume: 14 Issue: 38 Pages: 8385-8396
- DOI
  10.1021/acs.jpclett.3c01440
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06924, KAKENHI-PROJECT-20K16262, KAKENHI-PLANNED-21H05250, KAKENHI-PUBLICLY-22H05537, KAKENHI-PUBLICLY-23H04278, KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-23K23476
[Journal Article] Nanoscopic Assessment of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM.2023
- Author(s)
  Keesiang Lim, Goro Nishide, Elma Sakinatus Sajidah, Tomoyoshi Yamano, Yujia Qiu, Takeshi Yoshida, Akiko Kobayashi, Masaharu Hazawa, Toshio Ando, Rikinari Hanayama, Richard W Wong
- Journal Title
  
  Nano letters
  
  Volume: 23 Issue: 2 Pages: 619-628
- DOI
  10.1021/acs.nanolett.2c04270
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07065, KAKENHI-PROJECT-21K07173, KAKENHI-PROJECT-22K06924, KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-20K16262, KAKENHI-PUBLICLY-22H05537, KAKENHI-PUBLICLY-23H04278, KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-23K23476
[Journal Article] Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells2023
- Author(s)
  Hazawa M, Ikliptikawati DK, Iwashima Y, Lin DC, Jiang Y, Qiu Y, Makiyama K, Matsumoto K, Kobayashi A, Nishide G, Keesiang L, Yoshino H, Minamoto T, Suzuki T, Kobayashi I, Meguro-Horike M, Jiang YY, Nishiuchi T, Konno H, Koeffler HP, Hosomichi K, Tajima A, Horike SI, Wong RW.
- Journal Title
  
  Cell Chemical Biology
  
  Volume: － Issue: 4 Pages: 792-804.e7
- DOI
  10.1016/j.chembiol.2023.10.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07691, KAKENHI-PUBLICLY-22H05537, KAKENHI-PUBLICLY-23H04278, KAKENHI-PUBLICLY-24H01276, KAKENHI-PROJECT-22K06880, KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K06924, KAKENHI-PROJECT-23K23476, KAKENHI-PROJECT-23K27544, KAKENHI-PROJECT-23K27835, KAKENHI-PROJECT-24K18449
[Journal Article] Recent advances in sensing the inter-biomolecular interactions at the nanoscale ? A comprehensive review of AFM-based force spectroscopy2023
- Author(s)
  Lostao Anabel、Lim KeeSiang、Pallar?s Mar?a Carmen、Ptak Arkadiusz、Marcuello Carlos
- Journal Title
  
  International Journal of Biological Macromolecules
  
  Volume: 238 Pages: 124089-124089
- DOI
  10.1016/j.ijbiomac.2023.124089
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16262
[Journal Article] NSP9 of SARS-CoV-2 attenuates nuclear transport by hampering nucleoporin 62 dynamics and functions in host cells2022
- Author(s)
  Makiyama Kei、Hazawa Masaharu、Kobayashi Akiko、Lim Keesiang、Voon Dominic C.、Wong Richard W.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 586 Pages: 137-142
- DOI
  10.1016/j.bbrc.2021.11.046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-20K16262, KAKENHI-PUBLICLY-21H05744, KAKENHI-PUBLICLY-22H05537, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-23K23476
[Journal Article] Spatiotemporal tracking of small extracellular vesicle nanotopology in response to physicochemical stresses revealed by HS-AFM.2022
- Author(s)
  Elma Sakinatus Sajidah, Keesiang Lim, Tomoyoshi Yamano, Goro Nishide, Yujia Qiu, Takeshi Yoshida, Hanbo Wang, Akiko Kobayashi, Masaharu Hazawa, Firli R P Dewi, Rikinari Hanayama, Toshio Ando, Richard W Wong
- Journal Title
  
  Journal of extracellular vesicles
  
  Volume: 11 Issue: 11 Pages: 12275-12275
- DOI
  10.1002/jev2.12275
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07065, KAKENHI-PROJECT-21K07173, KAKENHI-PROJECT-22K06924, KAKENHI-PROJECT-20K16262, KAKENHI-PUBLICLY-21H05744, KAKENHI-PUBLICLY-22H05537, KAKENHI-PROJECT-22H00405, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-23K23476
[Journal Article] Discovery of a Novel Aminocyclopropenone Compound That Inhibits BRD4-Driven Nucleoporin NUP210 Expression and Attenuates Colorectal Cancer Growth2022
- Author(s)
  Kondo Hiroya、Mishiro Kenji、Iwashima Yuki、Qiu Yujia、Kobayashi Akiko、Lim Keesiang、Domoto Takahiro、Minamoto Toshinari、Ogawa Kazuma、Kunishima Munetaka、Hazawa Masaharu、Wong Richard W.
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 3 Pages: 317-317
- DOI
  10.3390/cells11030317
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-19K07710, KAKENHI-PROJECT-20K15953, KAKENHI-PROJECT-19H03727, KAKENHI-PROJECT-20K16262, KAKENHI-PUBLICLY-21H05744, KAKENHI-PUBLICLY-22H05537, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-23K24403, KAKENHI-PROJECT-23K23476
[Journal Article] High-Speed Atomic Force Microscopy Reveals Spatiotemporal Dynamics of Histone Protein H2A Involution by DNA Inchworming2021
- Author(s)
  Nishide Goro、Lim Keesiang、Mohamed Mahmoud Shaaban、Kobayashi Akiko、Hazawa Masaharu、Watanabe-Nakayama Takahiro、Kodera Noriyuki、Ando Toshio、Wong Richard W.
- Journal Title
  
  The Journal of Physical Chemistry Letters
  
  Volume: 12 Issue: 15 Pages: 3837-3846
- DOI
  10.1021/acs.jpclett.1c00697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-19K07398, KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-20K16262
[Journal Article] How SARS-CoV-2 and Other Viruses Build an Invasion Route to Hijack the Host Nucleocytoplasmic Trafficking System2021
- Author(s)
  Sajidah Elma Sakinatus、Lim Keesiang、Wong Richard W.
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 6 Pages: 1424-1424
- DOI
  10.3390/cells10061424
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-20K16262
[Journal Article] Millisecond dynamic of SARS‐CoV‐2 spike and its interaction with ACE2 receptor and small extracellular vesicles2021
- Author(s)
  Lim Keesiang、Nishide Goro、Yoshida Takeshi、Watanabe‐Nakayama Takahiro、Kobayashi Akiko、Hazawa Masaharu、Hanayama Rikinari、Ando Toshio、Wong Richard W.
- Journal Title
  
  Journal of Extracellular Vesicles
  
  Volume: 10 Issue: 14
- DOI
  10.1002/jev2.12170
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-21K07173, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-20K16262
[Journal Article] High-Speed AFM Reveals Molecular Dynamics of Human Influenza A Hemagglutinin and Its Interaction with Exosomes2020
- Author(s)
  Lim Keesiang、Kodera Noriyuki、Wang Hanbo、Mohamed Mahmoud Shaaban、Hazawa Masaharu、Kobayashi Akiko、Yoshida Takeshi、Hanayama Rikinari、Yano Seiji、Ando Toshio、Wong Richard W.
- Journal Title
  
  Nano Letters
  
  Volume: 20 Issue: 9 Pages: 6320-6328
- DOI
  10.1021/acs.nanolett.0c01755
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-20K07568, KAKENHI-PROJECT-19K22578, KAKENHI-PROJECT-20K16262, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-19K23841
[Presentation] Journey to the Nucleus2024
- Author(s)
  Lim Kee Siang
- Organizer
  The 8th WPI NanoLSI Symposium
- Data Source
  KAKENHI-PROJECT-24K18449
[Presentation] Nanoscopic Elucidation of Molecular Trafficking in Cells using High-Speed AFM2024
- Author(s)
  Lim Kee Siang
- Organizer
  The 12th Singapore International Chemistry Conference (SICC-12)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K18449
[Presentation] Nanoscopic Investigation of Real-Time Conformational Dynamics of Condensins using High-Speed Atomic Force Microscopy2024
- Author(s)
  Lim Kee Siang
- Organizer
  The 9th International Symposium of Practical Surface Analysis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K18449
[Presentation] Nanoscopic Evaluation of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM.2024
- Author(s)
  Lim Kee Siang
- Organizer
  The 4th Meeting of Cross-Scale Biology Conference
- Data Source
  KAKENHI-PROJECT-24K18449
[Presentation] Nanoscopic Evaluation of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM2023
- Author(s)
  Keesiang Lim
- Organizer
  the 7th WPI NanoLSI Symposium
- Data Source
  KAKENHI-PROJECT-20K16262
[Presentation] Nanoscopic Evaluation of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM.2023
- Author(s)
  Keesiang Lim
- Organizer
  The 70th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-20K16262
[Presentation] Nanoscopic Evaluation of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM2023
- Author(s)
  Keesiang Lim
- Organizer
  The 23rd annual meeting of the Protein Science Society of Japan
- Data Source
  KAKENHI-PROJECT-20K16262
[Presentation] Spatiotemporal tracking of SARS-CoV-2 spike (S) protein and its interaction with ACE2 receptor and small extracellular vesicles2022
- Author(s)
  Keesiang Lim
- Organizer
  he 60th Annual Meeting of the Japanese Society for Biophysics
- Data Source
  KAKENHI-PROJECT-20K16262
[Presentation] Millisecond tracking of structural dynamics of SARS-CoV-2 spike protein and its interaction with ACE2 receptor and small extracellular vesicles.2022
- Author(s)
  Keesiang Lim
- Organizer
  The 95th Annual Meeting of the Japanese Society for Biochemistry
- Data Source
  KAKENHI-PROJECT-20K16262
[Presentation] Structural dynamics of SARS-CoV-2 spike (S) protein and its interaction with ACE2 receptor and small extracellular vesicle2022
- Author(s)
  Keesiang Lim
- Organizer
  The 69th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-20K16262
[Presentation] Structural dynamics of SARS-CoV-2 spike (S) protein and its interaction with ACE2 receptor and small extracellular vesicles2022
- Author(s)
  Keesiang Lim
- Organizer
  Cross-Scale Biology 1st Wakate meeting
- Data Source
  KAKENHI-PROJECT-20K16262
[Presentation] Conformational dynamics of SARS-CoV-2 spike (S) protein and its interaction with ACE2 receptor and small extracellular vesicles.2022
- Author(s)
  Keesiang Lim
- Organizer
  The 74th Annual Meeting of the Japanese Society for Cell Biology
- Data Source
  KAKENHI-PROJECT-20K16262
[Presentation] 高速 AFM を用いた DNA インチワーミングによるヒストン H2A ラッピング動態の実時空間イメージング2021
- Author(s)
  西出梧朗、Keesiang Lim、Mahmoud Shaaban Mohamed、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  日本生化学会北陸支部第 39 回大会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 高速 AFM によるヒストン H2A トポグラフィーとその DNA コンパクション時の時空間ダイナミクスの解明2021
- Author(s)
  西出梧朗、Keesiang Lim、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] Investigation of real-time dynamic histone H2A-DNA interaction and H2A-DNA condensation/de-condensation using high-speed AFM2021
- Author(s)
  西出梧朗、Keesiang LIM、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard WONG
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 核膜孔複合体による核膜近傍での転写制御機構2021
- Author(s)
  岩嶋友紀、羽澤勝治、Qiu Yujia、Dini Kurnia Ikliptikawati、西出梧朗、小林亜紀子、Lim Kee Siang、Richard Wong
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 核内相分離の制御を可能とする新規アミノシクロプロペノン化合物の発見2021
- Author(s)
  近藤寛弥、三代憲司、岩嶋友紀、Qiu Yujia、稲葉有香、小林亜紀子、Keesiang Lim、源利成、小川数馬、國嶋崇隆、羽澤勝治、Richard Wong
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 高速AFMを用いたヒストンH2A-DNA実時空間イメージングによるヌクレオソーム凝縮プロセスとその環境の解明2021
- Author(s)
  西出梧朗、Keesiang Lim、Mahmoud Shaaban Mohamed、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第94回日本生化学大会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 核膜孔複合体による転写制御機構2021
- Author(s)
  岩嶋友紀、羽澤勝治、Qiu Yujia、Dini Kurnia Ikliptikawati1、西出梧朗、小林亜紀子、Lim Kee Siang、Richard Wong
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] ヒストンH2A-DNAダイナミクスの実時空間イメージング2021
- Author(s)
  西出梧朗、Keesiang Lim、小林亜紀子、羽澤勝治、稲葉有香、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] 高速 AFM を用いた DNA インチワーミングによるヒストン H2A ラッピング動態の実時空間イメージング2021
- Author(s)
  西出梧朗、Keesiang Lim、小林亜紀子、羽澤勝治、中山隆宏、古寺哲幸、安藤敏夫、Richard Wong
- Organizer
  第73回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] Molecular Dynamic of Coronavirus Spike Protein2021
- Author(s)
  Keesiang Lim
- Organizer
  The Molecular Biology Society of Japan
- Data Source
  KAKENHI-PROJECT-20K16262
[Presentation] Molecular Dynamic of Coronavirus Spike Protein2021
- Author(s)
  Keesiang Lim, Goro Nishide, Takeshi Yoshida, Takahiro Watanabe-Nakayama, Akiko Kobayashi, Masaharu Hazawa, Rikinari Hanayama, Toshio Ando, Richard W. Wong
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19043
[Presentation] High-Speed AFM Reveals Molecular Dynamics of Human Influenza A Hemagglutinin and Its Interaction with Exosomes2020
- Author(s)
  Lim Kee Siang
- Organizer
  WPI NanoLSI Symposium (4th)
- Data Source
  KAKENHI-PROJECT-20K16262
[Presentation] High-Speed AFM Reveals Molecular Dynamics of Human Influenza A Hemagglutinin and Its Interaction with Exosomes2020
- Author(s)
  Lim Kee Siang
- Organizer
  MBSJ (The Molecular Biology Society of Japan) 2020
- Data Source
  KAKENHI-PROJECT-19K23841
[Presentation] Direct visualization of avian influenza H5N1 hemagglutinin precursor and its conformational changes by high-speed atomic force microscopy.2020
- Author(s)
  Lim Kee Siang
- Organizer
  1st WPI NanoLSI-iCeMS Joint Symposium on Nanoimaging and Advanced Materials for Life Science
- Data Source
  KAKENHI-PROJECT-19K23841
[Presentation] High-Speed AFM Reveals Molecular Dynamics of Human Influenza A Hemagglutinin and Its Interaction with Exosomes2020
- Author(s)
  Lim Kee Siang
- Organizer
  MBSJ (The Molecular Biology Society of Japan) 2020
- Data Source
  KAKENHI-PROJECT-20K16262
[Presentation] High-Speed AFM Reveals Molecular Dynamics of Human Influenza A Hemagglutinin and Its Interaction with Exosomes2020
- Author(s)
  Lim Kee Siang
- Organizer
  WPI NanoLSI Symposium (4th)
- Data Source
  KAKENHI-PROJECT-19K23841
[Presentation] Direct visualization of avian influenza H5N1 Hemagglutinin precursor and its conformational change by high-speed atomic force microscopy.2019
- Author(s)
  Lim Kee Siang
- Organizer
  MBSJ
- Data Source
  KAKENHI-PROJECT-19K23841

1. Wong Richard (30464035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. 小林亜紀子 (00345662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
3. 羽澤勝治 (40622460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. OKADA Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 山野友義

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 安藤敏夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 吉野浩教

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 井上啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

LIM KEE SIANG ＬＩＭ ＫＥＥ・ＳＩＡＮＧ

Lim Kee Siang LIM KEE・SIANG

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Nanoscopic elucidation of dynamic behavior of RNA viral nucleocapsid proteins using high-speed atomic force microscopy (HS-AFM)Principal Investigator

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Functional Dynamics of Liquid-Liquid Phase Separation Mediated by Nuclear Pore Complex

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Real-time observation of native conformations and molecular behaviors of viral fusion proteins using high-speed atomic force microscopy (HS-AFM)Principal Investigator

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Direct visualization of conformational dynamics of hemagglutinin and interaction between hemagglutinin and exosomes using high-speed atomic force microscopy.Principal Investigator

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[Journal Article] Nanoscopic Profiling of Small Extracellular Vesicles via High‐Speed Atomic Force Microscopy (HS‐AFM) Videography2025

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[Journal Article] Strategies for the Viral Exploitation of Nuclear Pore Transport Pathways2025

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[Journal Article] Zooming into Gene Activation: Estrogen Receptor α Dimerization and DNA Binding Visualized by High-Speed Atomic Force Microscopy2025

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[Journal Article] Spatiotemporal dynamics of protamine-DNA condensation revealed by high-speed atomic force microscopy2025

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[Journal Article] Phase-separated super-enhancers confer an innate radioresistance on genomic DNA2024

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[Journal Article] An Efficient Method for Isolating and Purifying Nuclei from Mice Brain for Single-Molecule Imaging Using High-Speed Atomic Force Microscopy2024

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[Journal Article] Crafty mimicry grants nuclear pore entry to HIV2024

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[Journal Article] Nanoimaging of SARS-CoV-2 viral invasion toward the nucleus and genome2024

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[Journal Article] Nanoscopic Elucidation of Spontaneous Self-Assembly of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Open Reading Frame 6 (ORF6) Protein2023

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[Journal Article] Nanoscopic Assessment of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM.2023

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[Journal Article] Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells2023

LIM KEE SIANG ＬＩＭＫＥＥ・ＳＩＡＮＧ