Osana Shion 長名シオン

Researcher Number	60868131
Other IDs
Affiliation (Current)	2025: 国士舘大学, 体育学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 国士舘大学, 体育学部, 講師 2023: 東北大学, 医工学研究科, 特任助教 2022: 電気通信大学, 大学院情報理工学研究科, 特別研究員 2020 – 2021: 東北大学, 医工学研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 59020:Sports sciences-related Except Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 59020:Sports sciences-related
Keywords	Principal Investigator アミノペプチダーゼ / アミノ酸 / プロテアソーム / 骨格筋 / 筋分化 / 筋芽細胞 / サルコペニア Except Principal Investigator オリゴペプチド / アミノペプチダーゼ / 筋衛星細胞 … More / 筋芽細胞 / 次世代 / ビタミンD / エピゲノム / 脂肪組織 / 糖代謝 / 肝臓 / エピジェネティクス / 運動 / 妊娠 / 習慣的運動 / 糖尿病 / 肥満 / SOD3 / エクサカイン / プラセントカイン / 胎盤 / 妊娠期運動 / 分化 / タンパク分解 / 骨格筋 Less

Contribution of post-proteolytic pathways to skeletal muscle volume
- Principal Investigator
  
  永富良一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tohoku University
Elucidation of the regulation mechanism of myogenic differentiation by aminopeptidasePrincipal Investigator
- Principal Investigator
  
  長名シオン
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Kokushikan University
The role of post-proteolytic aminopeptidases in skeletal muscle homeostasis
- Principal Investigator
  
  Nagatomi Ryoichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tohoku University
Mechanism of the beneficial effects of maternal exercise on next generation health focusing on maternal organs, placenta, and fetal tissues
- Principal Investigator
  
  Kusuyama Joji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Tokyo Medical and Dental University
  Tohoku University
Elucidation of Amino Acid Ecosystem in Skeletal Muscle CellsPrincipal Investigator
- Principal Investigator
  
  Osana Shion
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Kokushikan University
  The University of Electro-Communications
  Tohoku University

All 2023 2022 2021 2020

All Journal Article Presentation Patent

[Journal Article] Chronic repetitive cooling and caffeine-induced intracellular Ca<sup>2+</sup> elevation differentially impact adaptations in slow- and fast-twitch rat skeletal muscles2023
- Author(s)
  Takagi Ryo、Tabuchi Ayaka、Hayakawa Kosei、Osana Shion、Yabuta Hiroya、Hoshino Daisuke、Poole David C.、Kano Yutaka
- Journal Title
  
  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  
  Volume: 325 Issue: 2 Pages: R172-R180
- DOI
  10.1152/ajpregu.00063.2023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K16670, KAKENHI-PROJECT-22KJ1361, KAKENHI-PROJECT-20K19478
[Journal Article] Curcumin analog GO-Y030 inhibits tumor metastasis and glycolysis2023
- Author(s)
  MaruYama Takashi、Miyazaki Hirofumi、Komori Taishi、Osana Shion、Shibata Hiroyuki、Owada Yuji、Kobayashi Shuhei
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 174 Issue: 6 Pages: 511-518
- DOI
  10.1093/jb/mvad066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K16670, KAKENHI-PROJECT-22KJ1361, KAKENHI-PROJECT-20KK0225, KAKENHI-PROJECT-22K19724, KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-23K24783
[Journal Article] Cooling‐promoted myogenic differentiation of murine bone marrow mesenchymal stem cells through <scp>TRPM8</scp> activation in?vitro2023
- Author(s)
  Takagi Ryo、Takegaki Junya、Osana Shion、Kano Yutaka、Konishi Satoshi、Fujita Satoshi
- Journal Title
  
  Physiological Reports
  
  Volume: 11 Issue: 23
- DOI
  10.14814/phy2.15855
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K17742, KAKENHI-PROJECT-23K16670, KAKENHI-PROJECT-22KJ1361, KAKENHI-PROJECT-21KK0177, KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-23K24732
[Journal Article] The aminopeptidase LAP3 suppression accelerates myogenic differentiation via the AKT‐TFE3 pathway in C2C12 myoblasts2023
- Author(s)
  Osana Shion、Kitajima Yasuo、Naoki Suzuki、Murayama Kazutaka、Takada Hiroaki、Tabuchi Ayaka、Kano Yutaka、Nagatomi Ryoichi
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 238 Issue: 9 Pages: 2103-2119
- DOI
  10.1002/jcp.31070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K16670, KAKENHI-PROJECT-22KJ1361, KAKENHI-PROJECT-21K19720, KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-21H04857
[Journal Article] Lactate promotes neuronal differentiation of SH-SY5Y cells by lactate-responsive gene sets through NDRG3-dependent and -independent manners2023
- Author(s)
  Xu Yidan、Kusuyama Joji、Osana Shion、Matsuhashi Satayuki、Li Longfei、Takada Hiroaki、Inada Hitoshi、Nagatomi Ryoichi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 6 Pages: 104802-104802
- DOI
  10.1016/j.jbc.2023.104802
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K16670, KAKENHI-PROJECT-22KJ0296, KAKENHI-PROJECT-22KJ1361, KAKENHI-PROJECT-20K19478
[Journal Article] Little involvement of recycled-amino acids from proteasomal proteolysis in de novo protein synthesis2022
- Author(s)
  Shion Osana, Yasuo Kitajima, Suzuki Naoki, Hiroaki Takada, Kazutaka Murayama, Yutaka Kano, Ryoichi Nagatomi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 634 Pages: 40-47
- DOI
  10.1016/j.bbrc.2022.09.113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-21H04857, KAKENHI-PROJECT-22KJ1361, KAKENHI-PROJECT-20H04078
[Journal Article] タンパク質分解経路が筋芽細胞の増殖と分化に与える影響2021
- Author(s)
  長名シオン, 永富良一
- Journal Title
  
  体力科学
  
  Volume: 70 Pages: 60-60
- NAID
  130007967736
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19478
[Journal Article] Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations2021
- Author(s)
  Mitsuzawa S, Suzuki N, Akiyama T, Ishikawa M, Sone T, Kawada J, Funayama R, Shirota M, Mitsuhashi H, Morimoto S, Ikeda K, Shijo T, Ohno A, Nakamura N, Ono H, Ono R, Osana S, Nakagawa T, Nishiyama A, Izumi R, Kaneda S, Ikeuchi Y, Nakayama K, Fujii T, Warita H, Okano H, Aoki M.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 16 Issue: 6 Pages: 1527-1541
- DOI
  10.1016/j.stemcr.2021.04.021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07837, KAKENHI-PROJECT-20K05288, KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-21K07411, KAKENHI-PROJECT-20K16593, KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-20K07897
[Journal Article] Puromycin‐sensitive aminopeptidase is required for C2C12 myoblast proliferation and differentiation2020
- Author(s)
  Osana Shion、Kitajima Yasuo、Suzuki Naoki、Nunomiya Aki、Takada Hiroaki、Kubota Takahiro、Murayama Kazutaka、Nagatomi Ryoichi
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 236 Issue: 7 Pages: 5293-5305
- DOI
  10.1002/jcp.30237
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-18H04080, KAKENHI-PROJECT-21K19720, KAKENHI-PROJECT-20H04078
[Journal Article] siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation2020
- Author(s)
  Osana Shion、Kitajima Yasuo、Suzuki Naoki、Xu Yidan、Murayama Kazutaka、Nagatomi Ryoichi
- Journal Title
  
  Experimental Cell Research
  
  Volume: 397 Issue: 1 Pages: 112337-112337
- DOI
  10.1016/j.yexcr.2020.112337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-18H04080
[Patent] 荷重センサおよび荷重検出装置2021
- Inventor(s)
  成田史生,井上久美,栗田大樹,長名シオン他
- Industrial Property Rights Holder
  成田史生,井上久美,栗田大樹,長名シオン他
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K19478
[Presentation] LAP3の発現抑制はC2C12の筋分化を促進する2023
- Author(s)
  長名シオン
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K19478
[Presentation] LAP3の発現抑制はC2C12の筋分化を促進する2023
- Author(s)
  長名シオン
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K16670
[Presentation] ロイシンアミノペプチダーゼLAP3の発現抑制は筋分化を促進する,2023
- Author(s)
  長名シオン
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21H04857
[Presentation] アミノペプチダーゼによる筋分化制御メカニズムの解明2022
- Author(s)
  長名シオン
- Organizer
  日本筋学会
- Data Source
  KAKENHI-PROJECT-20K19478
[Presentation] アミノペプチダーゼによる筋分化制御メカニズムの解明2022
- Author(s)
  Shion Osana, Yasuo Kitajima, Suzuki Naoki, Hiroaki Takada, Kazutaka Murayama, Yutaka Kano, Ryoichi Nagatomi.
- Organizer
  第8回日本筋学会
- Data Source
  KAKENHI-PROJECT-21H04857
[Presentation] ペプチド分解酵素による筋分化制御機構の解明2022
- Author(s)
  長名シオン, 北嶋康雄, 鈴木直輝, 村山和隆, 永富良一, 狩野豊
- Organizer
  第77回日本体力医学会
- Data Source
  KAKENHI-PROJECT-21H04857
[Presentation] ペプチド分解酵素による筋分化制御機構の解明2022
- Author(s)
  長名シオン
- Organizer
  日本体力医学会
- Data Source
  KAKENHI-PROJECT-20K19478
[Presentation] ペプチド分解酵素LAP3による筋量調節機構の解明2022
- Author(s)
  長名シオン, 北嶋康雄, 鈴木直輝, 高田拓明, 村山和隆, 狩野豊, 永富良一
- Organizer
  第9回骨格筋生物学研究会
- Data Source
  KAKENHI-PROJECT-21H04857
[Presentation] ペプチド分解酵素アミノペプチダーゼによる筋芽細胞の分化制御2021
- Author(s)
  長名シオン, 永富良一
- Organizer
  日本体力医学会
- Data Source
  KAKENHI-PROJECT-20K19478
[Presentation] Puromycin-sensitive aminopeptidase is involved in myogenic differentiation through cell polarity regulation2021
- Author(s)
  長名シオン
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K19478
[Presentation] ペプチド分解酵素アミノペプチダーゼによる筋芽細胞の分化制御2021
- Author(s)
  長名シオン、永富良一
- Organizer
  日本体力医学会
- Data Source
  KAKENHI-PROJECT-21H04857
[Presentation] 骨格筋細胞におけるアミノペプチダーゼの役割2020
- Author(s)
  長名シオン
- Organizer
  骨格筋生物学研究会
- Data Source
  KAKENHI-PROJECT-20K19478
[Presentation] Inhibition of leucine aminopeptidase affects myocyte proliferation and differentiation2020
- Author(s)
  Shion Osana, Kazutaka Murayama, Naoki Suzuki, Hiroaki Takada, Takahiro Kubota, Ryoichi Nagatomi
- Organizer
  Experimental Biology 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K19478
[Presentation] タンパク質分解経路が筋芽細胞の増殖と分化に与える影響2020
- Author(s)
  長名シオン, 永富良一
- Organizer
  日本体力医学会
- Data Source
  KAKENHI-PROJECT-20K19478

1. Nagatomi Ryoichi (20208028)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. 神崎展 (10272262)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 村山和隆 (40400452)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 鈴木直輝 (70451599)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. Kusuyama Joji (70596105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 木村友彦 (50454830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小塚智沙代 (70722370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 竹垣淳也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 中川直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Osana Shion 長名 シオン

Research Projects

Research Products

Co-Researchers

Contribution of post-proteolytic pathways to skeletal muscle volume

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the regulation mechanism of myogenic differentiation by aminopeptidasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of post-proteolytic aminopeptidases in skeletal muscle homeostasis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of the beneficial effects of maternal exercise on next generation health focusing on maternal organs, placenta, and fetal tissues

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of Amino Acid Ecosystem in Skeletal Muscle CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Chronic repetitive cooling and caffeine-induced intracellular Ca<sup>2+</sup> elevation differentially impact adaptations in slow- and fast-twitch rat skeletal muscles2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Curcumin analog GO-Y030 inhibits tumor metastasis and glycolysis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cooling‐promoted myogenic differentiation of murine bone marrow mesenchymal stem cells through <scp>TRPM8</scp> activation in?vitro2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The aminopeptidase LAP3 suppression accelerates myogenic differentiation via the AKT‐TFE3 pathway in C2C12 myoblasts2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lactate promotes neuronal differentiation of SH-SY5Y cells by lactate-responsive gene sets through NDRG3-dependent and -independent manners2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Little involvement of recycled-amino acids from proteasomal proteolysis in de novo protein synthesis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] タンパク質分解経路が筋芽細胞の増殖と分化に与える影響2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Puromycin‐sensitive aminopeptidase is required for C2C12 myoblast proliferation and differentiation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation2020

Osana Shion 長名シオン