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DOI HIROYOSHI  土井 浩義

ORCIDConnect your ORCID iD *help
Researcher Number 60906337
Other IDs
Affiliation (based on the past Project Information) *help 2021 – 2022: 九州大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 55050:Anesthesiology-related / 0905:Surgery of the organs maintaining homeostasis and related fields
Keywords
Principal Investigator
麻酔薬 / クロマチン / ミダゾラム / 神経幹細胞 / ニューロン新生 / クロマチンポテンシャル / ATAC-seq / 認知機能低下 / 増殖抑制 / 学習・記憶 … More / 自発的運動 / GABA / 麻酔薬曝露 / 記憶・学習障害 Less
  • Research Projects

    (2 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (1 People)
  •  発達期麻酔薬曝露による神経幹細胞のクロマチンポテンシャル制御機構の解明Principal Investigator

    • Principal Investigator
      土井 浩義
    • Project Period (FY)
      2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Kyushu University
  •  Elucidation of molecular mechanisms underlying cognitive decline at adult stage induced by neonatal exposure to midazolam and development of a therapeutic strategyPrincipal Investigator

    • Principal Investigator
      DOI HIROYOSHI
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0905:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Kyushu University

All 2022 2021

All Journal Article Presentation

  • [Journal Article] Early-life midazolam exposure persistently changes chromatin accessibility to impair adult hippocampal neurogenesis and cognition2021

    • Author(s)
      Doi Hiroyoshi、Matsuda Taito、Sakai Atsuhiko、Matsubara Shuzo、Hoka Sumio、Yamaura Ken、Nakashima Kinichi
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 38

    • DOI

      10.1073/pnas.2107596118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02808, KAKENHI-PROJECT-21K20956
  • [Presentation] 幼若期ミダゾラム曝露による神経幹細胞のクロマチン構造変化2022

    • Author(s)
      土井 浩義, 松田 泰斗, 中島 孝輔, 中島 欽一, 山浦 健
    • Organizer
      日本麻酔科学会第69回学術集会
    • Data Source
      KAKENHI-PROJECT-22K16603
  • [Presentation] 幼若期ミダゾラム曝露による神経幹細胞のクロマチン構造変化2022

    • Author(s)
      土井 浩義、松田 泰斗、中島 孝輔 、中島 欽一、山浦 健
    • Organizer
      日本麻酔科学会 第69回学術集会
    • Data Source
      KAKENHI-PROJECT-21K20956
  • [Presentation] 生後早期のミダゾラム曝露はクロマチンのアクセス性を持続的に変化させ、成体ニュ―ロン新生および認知機能を低下させる2022

    • Author(s)
      土井 浩義、松田 泰斗、山浦 健、中島 欽一
    • Organizer
      NEURO2022
    • Data Source
      KAKENHI-PROJECT-22K16603
  • [Presentation] Midazolam anesthesia modifies chromatin landscape to promote neural stem cell dormancy2022

    • Author(s)
      Hiroyoshi Doi, Taito Matsuda, Ken Yamaura, , Kinichi Nakashima
    • Organizer
      NEURO 2022
    • Data Source
      KAKENHI-PROJECT-21K20956
  • 1.  松田 泰斗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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