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NAGAYOSHI YU  永芳 友

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Nagayoshi Yu  永芳 友

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Researcher Number 60908028
Other IDs
Affiliation (Current) 2026: 熊本大学, 大学院生命科学研究部(医), 特任講師
Affiliation (based on the past Project Information) *help 2025: 熊本大学, 大学院生命科学研究部(医), 特任講師
2022 – 2024: 熊本大学, 大学院生命科学研究部(医), 特任助教
2022: 熊本大学, 大学院生命科学研究部(医), 助教
2021: 熊本大学, 大学院生命科学研究部(医), 特定事業教員
Review Section/Research Field
Principal Investigator
Basic Section 53040:Nephrology-related / 0903:Organ-based internal medicine and related fields
Except Principal Investigator
Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords
Principal Investigator
修飾ヌクレオシド / リキッドバイオプシー / 慢性腎不全 / 糖尿病性腎症 / RNA修飾病 / CDKAL1 / 足細胞 / RNA修飾 / 尿中バイオマーカー / 腎疾患 / バイオマーカー … More
Except Principal Investigator
… More RNA修飾 / RNA修飾病 / バイオマーカー / 心腎連関 / 慢性腎臓病 / 修飾ヌクレオシド Less
  • Research Projects

    (4 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (2 People)
  •  修飾ヌクレオシド解析による腎疾患の分子メカニズム解明と新規評価法の開発Principal Investigator

    • Principal Investigator
      永芳 友
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Kumamoto University
  •  Biological significance of modified nucleosides in homeostasis regulation and their role in cardiorenal interaction upon renal failure

    • Principal Investigator
      Mukoyama Masashi
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Kumamoto University
  •  Exploring the Molecular Regulation of podocyte function by tRNA modification enzyme CDKAL1Principal Investigator

    • Principal Investigator
      Nagayoshi Yu
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Kumamoto University
  •  Development of a Novel Diagnostic Method for Renal Disease by Profilings of Modified Nucleosides in UrinePrincipal Investigator

    • Principal Investigator
      Nagayoshi Yu
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0903:Organ-based internal medicine and related fields
    • Research Institution
      Kumamoto University

All 2025 2024 2023

All Journal Article Presentation

  • [Journal Article] Bacteria-specific modified nucleoside is released and elevated in urine of patients with bacterial infections2025

    • Author(s)
      Yamamura Ryosuke、Nagayoshi Yu、Nishiguchi Kayo、Kaneko Hitomi、Yamamoto Keiichi、Matsushita Koki、Shimamura Miho、Kunisawa Akihiro、Sakakida Korin、Chujo Takeshi、Adachi Masataka、Kakizoe Yutaka、Izumi Yuichiro、Kuwabara Takashige、Mukoyama Masashi、Tomizawa Kazuhito
    • Journal Title

      mBio

      Volume: 16 Issue: 1

    • DOI

      10.1128/mbio.03124-24

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-23K07676
  • [Journal Article] A Serine Protease Inhibitor, Camostat Mesilate, Suppresses Urinary Plasmin Activity and Alleviates Hypertension and Podocyte Injury in Dahl Salt-Sensitive Rats2023

    • Author(s)
      Iwata Yasunobu、Deng Qinyuan、Kakizoe Yutaka、Nakagawa Terumasa、Miyasato Yoshikazu、Nakagawa Miyuki、Nishiguchi Kayo、Nagayoshi Yu、Narita Yuki、Izumi Yuichiro、Kuwabara Takashige、Adachi Masataka、Mukoyama Masashi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 24 Issue: 21 Pages: 15743-15743

    • DOI

      10.3390/ijms242115743

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-23K07676, KAKENHI-PROJECT-21K08280
  • [Presentation] The molecular mechanism of innate immune response by bacteria-specific modified nucleosides2025

    • Author(s)
      Miho Shimamura, Yu Nagayoshi, Kayo Nishiguchi, Hitomi Kaneko, Ryosuke Yamamura, Kazuhito Tomizawa 
    • Organizer
      Anatomy-Physiology-Pharmacology Week in 2025 (APPW2025)
    • Data Source
      KAKENHI-PROJECT-23K18291
  • [Presentation] The relationship between the tRNA modification enzyme: CDKAL1 and the pathology of hepatocellular carcinoma2025

    • Author(s)
      Yuki Adachi, Yu Nagayoshi, Kayo Nishiguchi, Hitomi Kaneko Takeshi Chujo, Kazuhito Tomizawa
    • Organizer
      APPW2025
    • Data Source
      KAKENHI-PROJECT-23K18291
  • [Presentation] 細菌特異的修飾ヌクレオシドの排泄メカニズムと生理学的意義2024

    • Author(s)
      山村遼介、西口栞世、永芳 友、富澤一仁
    • Organizer
      第97回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-23K18291
  • [Presentation] The reactions of immune cells by bacteria specific modified nucleosides2024

    • Author(s)
      Miho Shimamura, Yu Nagayoshi, Kayo Nishiguchi, Hitomi Kaneko, Ryosuke Yamamura, Kazuhito Tomizawa 
    • Organizer
      第53回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K18291
  • [Presentation] 培養細胞培養液中エクソソームを用いた修飾ヌクレオシドプロファイリング解析2024

    • Author(s)
      高山泰享、金子 瞳、江越正敏、永芳 友
    • Organizer
      第24回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-23K18291
  • [Presentation] Elevation of modified nucleosides in blood by chronic kidney disease affect vascular endothelial cell proliferations2024

    • Author(s)
      Hitomi Kaneko, Yu Nagayoshi, Ryosuke Yamamura, Takeshi Chujo, Kazuhito Tomizawa
    • Organizer
      第101回日本生理学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K18291
  • [Presentation] 細菌における修飾ヌクレオシドの新規代謝物経路の探索2024

    • Author(s)
      西口栞世、永芳 友、山村遼介、富澤一仁
    • Organizer
      第97回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-23K18291
  • [Presentation] 細菌特異的修飾ヌクレオシドの排泄メカニズムと生理学的意義2023

    • Author(s)
      西口 栞、永芳 友、山村遼介、柿添 豊、安達政隆、富澤一仁、向山政志
    • Organizer
      第66回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K18291
  • [Presentation] 腎臓におけるtRNA修飾酵素CDKAL1の生理機能および足細胞機能との関連2023

    • Author(s)
      永田裕子、永芳 友、柿添 豊、安達政隆、仲里仁史、向山政志、富澤一仁
    • Organizer
      第66回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K18291
  • [Presentation] Plasmin inhibition attenuates ENaC activation and podocyte injury in Dahl salt-sensitive rats2023

    • Author(s)
      Yutaka Kakizoe, Yu Nagayoshi, Masashi Mukoyama, et al.
    • Organizer
      Annual Meeting of the American Society of Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18291
  • [Presentation] 修飾ヌクレオシドが織りなす新たな生体制御と腎不全に伴う血中濃度上昇から紐解く新規心腎連関分子メカニズムの解明2023

    • Author(s)
      永芳 友、山村遼介、安達政隆、柿添 豊、向山政志
    • Organizer
      第120回日本内科学会総会
    • Data Source
      KAKENHI-PROJECT-23K18291
  • [Presentation] 腎不全に伴う血中修飾ヌクレオシド上昇から紐解く新規心腎連関分子メカニズムの解明2023

    • Author(s)
      山村遼介、永芳 友、柿添 豊、安達政隆、富澤 一仁、向山政志
    • Organizer
      第66回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K18291
  • 1.  Mukoyama Masashi (40270558)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 2.  桑原 孝成
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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