Ozono Keigo 大薗慶吾

Researcher Number	60912847
Affiliation (Current)	2025: 九州大学, 大学病院, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 九州大学, 大学病院, 助教
Review Section/Research Field	Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55020:Digestive surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Except Principal Investigator 抗腫瘍効果 / 樹状細胞 / エクソソーム / 遊走能 / 浸潤能 / 癌治療法開発 / 活性化リンパ球 / 癌免疫治療 / CD8リンパ球 / PTPN3 … More / NOTCHシグナル / 肺癌 / 新規癌治療法開発 / 癌悪性形質 / 形態形成シグナル / 非小細胞肺がん / Notchシグナル / Hedgehogシグナル / MAML3 / 低酸素環境 / 再酸素化 / 転移 / 膵癌 / 癌新規治療法開発 / がん再発 / 細胞周期 / 癌休眠 / 膵癌転移 / C4orf47 / 癌免疫療法 / 抗原特異性 / リンパ球組織浸潤 / ネオ抗原 / がん免疫治療 / 単球 / ネオアンチゲン / 癌治療開発 / 増殖能 / C4orf３ / 新規治療法開発 / 癌微小環境 / チロシンキナーゼ / リン酸化経路 / CACNA1G / 肺NET / 腫瘍免疫 / CD4 / CD8 / 細胞傷害性Tリンパ球 / 非抗体型免疫チェックポイント阻害剤 / 癌組織浸潤リンパ球 / 新規がん免疫治療 / 薬剤スクリーニング / 低分子化合物 / CD4リンパ球 / 免疫チェックポイント阻害剤 Less

Development of cancer immunotherapy with monocyte stimulated by neoantigen-pulsed dendritic cells-derived exosome
- Principal Investigator
  
  大西秀哉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyushu University
Development of a new cancer immunotherapy using the exosome derived from neoantigen pulsed mature dendritic cells
- Principal Investigator
  
  永見雅代 (梅林雅代)
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
Analysis of the mechanism of pancreatic cancer metastasis targeting the kinetics of C4orf47 expression by reoxygenation
- Principal Investigator
  
  梁井公輔
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
Development of a new lung cancer therapy targeting a MAML3-Hh/NOTCH signaling pathway
- Principal Investigator
  
  中村勝也
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kyushu University
Development of cancer immunotherapy using non-receptor type immune checkpoint inhibitor targeting PTPN3
- Principal Investigator
  
  中山和典
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
Analysis of PTPN3-CACNA1G-TK phosphorylation pathway in lung NET
- Principal Investigator
  
  大西秀哉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kyushu University

All 2023 2022

All Journal Article Presentation

[Journal Article] PTPN3 inhibition contributes to the activation of the dendritic cell function to be a promising new immunotherapy target2023
- Author(s)
  Iwamoto N, Onishi H, Masuda S, Imaizumi A, Sakanashi K, Morisaki S, Nagao S, Koga S, Ozono K, Umebayashi M, Morisaki T, Nakamura M
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: 149(16) Issue: 16 Pages: 14619-14630
- DOI
  10.1007/s00432-023-05250-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08906, KAKENHI-PROJECT-22K08715, KAKENHI-PROJECT-23K08073, KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K09583, KAKENHI-PROJECT-23K24422
[Journal Article] PTPN3 could be a therapeutic target of pancreatic cancer2022
- Author(s)
  Onishi H, Iwamoto N, Sakanashi K, Koga S, Oyama Y, Yanai K, Nakamura K, Nagai S, Fujimura A, Nakayama K, Ozono K, Yamasaki A
- Journal Title
  
  Anticancer Res
  
  Volume: 42 Issue: 6 Pages: 2869-2874
- DOI
  10.21873/anticanres.15768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K08712, KAKENHI-PROJECT-21K08906, KAKENHI-PROJECT-21K09583, KAKENHI-PROJECT-22K08715, KAKENHI-PROJECT-20K09180, KAKENHI-PROJECT-23K24422
[Journal Article] Tropomyosin-related kinase B is a biomarker of prognosis and therapeutic target for malignant thymic epithelial tumors2022
- Author(s)
  Ozono K, Onishi H, Iwamoto N, Nakamura K, Miyoshi K, Nakamura M, Oda Y
- Journal Title
  
  Anticancer Res
  
  Volume: 42 Issue: 8 Pages: 3779-3787
- DOI
  10.21873/anticanres.15868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K08712, KAKENHI-PROJECT-21K08906, KAKENHI-PROJECT-22K08715, KAKENHI-PROJECT-20K09180, KAKENHI-PROJECT-23K24422
[Journal Article] Cancer therapy that targets the HEDGEHOG signaling pathway considering the cancer microenvironment2022
- Author(s)
  Onishi H, Nakamura K, Yanai K, Nagai S, Nakayama K, Oyama Y, Fujimura A, Ozono K, Yamasaki A
- Journal Title
  
  Oncol Rep
  
  Volume: 47(5) Issue: 5 Pages: 93-93
- DOI
  10.3892/or.2022.8304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22662, KAKENHI-PROJECT-20K09180, KAKENHI-PROJECT-21K08906, KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K08712, KAKENHI-PROJECT-21K09583, KAKENHI-PROJECT-22K08715, KAKENHI-PROJECT-23K24422
[Presentation] 低酸素環境で発現・活性化が亢進するシグナル系、新規分子を標的とした胸部悪性腫瘍に対する新規治療法開発2022
- Author(s)
  中村勝也、大西秀哉、古賀智子、永井俊太郎、山崎章生、大薗慶吾、内山明彦、中村雅史
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-23K24422
[Presentation] 低酸素環境で発現・活性化が亢進するシグナル系、新規分子を標的とした胸部悪性腫瘍に対する新規治療法開発2022
- Author(s)
  中村勝也、大西秀哉、古賀智子、永井俊太郎、山崎章生、大薗慶吾、内山明彦、中村雅史
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-22K08715

1. 大西秀哉 (30553276)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
2. 緒方久修 (70432945)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. 中村勝也 (60585743)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 山崎章生 (80404440)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 永見雅代 (80792209)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 中山和典 (30915252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山下智大 (30645635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 藤村晶子 (60892718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 片野光男 (10145203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中村雅史 (30372741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 中島欽一 (80302892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 森崎隆 (90291517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 梁井公輔 (10621055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 永井俊太郎 (90755240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Ozono Keigo 大薗 慶吾

Research Projects

Research Products

Co-Researchers

Development of cancer immunotherapy with monocyte stimulated by neoantigen-pulsed dendritic cells-derived exosome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a new cancer immunotherapy using the exosome derived from neoantigen pulsed mature dendritic cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the mechanism of pancreatic cancer metastasis targeting the kinetics of C4orf47 expression by reoxygenation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a new lung cancer therapy targeting a MAML3-Hh/NOTCH signaling pathway

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of cancer immunotherapy using non-receptor type immune checkpoint inhibitor targeting PTPN3

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of PTPN3-CACNA1G-TK phosphorylation pathway in lung NET

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] PTPN3 inhibition contributes to the activation of the dendritic cell function to be a promising new immunotherapy target2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PTPN3 could be a therapeutic target of pancreatic cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tropomyosin-related kinase B is a biomarker of prognosis and therapeutic target for malignant thymic epithelial tumors2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cancer therapy that targets the HEDGEHOG signaling pathway considering the cancer microenvironment2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] 低酸素環境で発現・活性化が亢進するシグナル系、新規分子を標的とした胸部悪性腫瘍に対する新規治療法開発2022

Author(s)

Organizer

Data Source

[Presentation] 低酸素環境で発現・活性化が亢進するシグナル系、新規分子を標的とした胸部悪性腫瘍に対する新規治療法開発2022

Author(s)

Organizer

Data Source

Ozono Keigo 大薗慶吾