KUDO Tsuyoshi 工藤剛

Researcher Number	70003407
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007 – 2008: Hirosaki University, Graduate School of Medicine, Assistant Professor 2005 – 2006: 弘前大学, 医学部, 助手 1992 – 1997: 弘前大学, 医学部, 助手 1986 – 1989: 弘前大学, 医学部, 助手
Review Section/Research Field	Principal Investigator 麻酔学 / Anesthesiology/Resuscitation studies Except Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / 麻酔学
Keywords	Principal Investigator ANP / Naloxane / Atrium cell / Rat / Catecholamine / Dynorphin / Enkepharin / Morphine / CompB / ACTH … More / c-GMP / オピオイド受容体 / フェンタニール / ナロキソン / 心房筋細胞 / ラット / カテコルアミン / ダイノルフィン / エンケファリン / モルフィン / DFK / HPLC / racemate / enatiomer / norketamine / ketamine / DFK麻酔 / ラセミ体 / 光学異性体 / HPLC測定法 / ノルケタミン / ケタミン / PRA / アルドステロン / フロセミド / トリナタファン / ニトロプレシッド / ニカルジピン / 降圧薬 … More Except Principal Investigator Aldosterone / ACTH / ノルエピネフリン / ラット / 大脳皮質 / マイクロダイアリーシス / buprenorphine / morphine / cancer pain / continuous epidural infusion pump / continuous epidural infusion / 日内変動 / ブプレノルフィン / モルヒネ / 癌性疼痛 / 硬膜外持続注入ポンプ / 硬膜外持続注入 / cyclic GMP / corticosterone / adrenal / <alpha>-human atrial natriuretic polypetide / Cyclic GMP / Cyclic AMP / エンドトキシンショック / cyclicGMP / コルチコステロン / Adosterone / 副腎 / 心房性ナトリウム利尿ホルモン / cerebrocortical slice / microdialysis / rat / noradrenaline / orexin / 静脈麻酔薬 / 吸入麻酔薬 / 神経組織 / ベンゾジアゼピン / α受容体作リガンド / 電撃痙攣療法 / 大脳皮質スライス / ノルアドレナリン / オレキシン / eyelash reflex / nasal reflex / 95% spectral edge frequency / median frequency / bispectral index / monitoring / propofol / Anaesthesia / Bispectral index / ケタミン血中濃度 / フェンタニール血中濃度 / プロポフォール血中濃度 / 脳波 / 麻酔深度 / 気管内挿管 / プロポフォール / 麻酔薬自動注入法 / 双スペクトラル解析脳波 / 全静脈麻酔 / Total intravenous anesthesia / Target controlled infusion / Ketamine / Fentanyl / Pharmacokinetics / コンピュータシュミレーション / ドロペリドール / 完全静脈麻酔 / 完全静脈麻酔法 / 自動投与法 / ケタミン / フェンタニール / 薬物動態学 / 麻酔科学 / 覚醒 / 麻酔の質 / 麻酔学 / UFP-803 / 麻酔 / HEK293-UII細胞 / UT受容体 / 細胞内Ca / 神経伝達物質 / ウロテンシンII / プロスタグランジンE_1 / グルタミン酸 / 脳虚血 Less

Study on a mechanism of emergence from general anesthesia-apply of the ascending arousal system for smooth recovery from general anesthesia
- Principal Investigator
  
  KUSHIKATA Tetsuya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
生理活性物質ウロテンシンIIの全身麻酔および睡眠への関与
- Principal Investigator
  
  HIROTA Kazuyoshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Brain orexinergic-noradrenergic neurons and mechanism of general anesthesia
- Principal Investigator
  
  HIROTA Kazuyoshi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Clinical study for target control infusion system with processed EEG
- Principal Investigator
  
  MATSUKI Akitomo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  HIROSAKI UNIVERSITY
Studies of Pharmacokinetic on Enatiomers of Ketamine and Norketamine during DFK AnesthesiaPrincipal Investigator
- Principal Investigator
  
  KUDO Tsuyoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  UNIVERSITY OF HIROSAKI
虚血脳蘇生時の神経伝達物質濃度変化と脳内サイトカインに関する研究
- Principal Investigator
  
  坂井哲博
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Pharmacokinetic study for target controlled infusion of ketamine and fentanyl
- Principal Investigator
  
  MATSUKI Akitomo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  HIROSAKI UNIVERSITY
降圧薬のラット心房性ナトリウム利尿ペプチド(r-ANP)分泌に及ぼす影響Principal Investigator
- Principal Investigator
  
  工藤剛
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  Hirosaki University
Study of the secretion of atrial natriuretic peptide (ANP) induced by morphine.Principal Investigator
- Principal Investigator
  
  KUDO Tsuyoshi
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  Hirasaki University
Epidural Treatment and Endocrine Response to Pain in Cancer Patients
- Principal Investigator
  
  OYAMA Tsutomu
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  麻酔学
- Research Institution
  University of Hirosaki School of Medicine
Effect of <alph>-Human Atrial Natriuretic Polypeptide on Adrenal Endocrine Function in Rats
- Principal Investigator
  
  KUDO Mihoko
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  University of Hirosaki School of Medicine

All 2010 2009 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] The Effects of Neuropeptide S on General Anesthesia in Rats2010
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Salvadori S, Calo G, Hirota K
- Journal Title
  
  Anesth Analg 112巻
  
  Pages: 845-849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] The Effects of Neuropeptide S on General Anesthesia in Rats2010
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Salvadori S , Cato G , Hirota K
- Journal Title
  
  Anes thAnalg
  
  Volume: 112 Pages: 845-849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Interaction between orexinergic neurons and NMDA receptors in the control of locus coeruleus-cerebrocortical noradrenergic activity of the rat2009
- Author(s)
  Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
- Journal Title
  
  Brain Res 1250巻
  
  Pages: 81-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Interaction between orexinergic neurons and NMDA receptors in the control oflocus coeruleus-cerebrocortical noradrenergic activity of the rat.2009
- Author(s)
  Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
- Journal Title
  
  Brain Res. 1250
  
  Pages: 81-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Orexin A decreases ketamine-induced anesthesia time in the rat : the relevance to brain noradrenergic neuronal activity.2009
- Author(s)
  Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
- Journal Title
  
  Anesth Analg. 108
  
  Pages: 491-495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] The effects of benzodiazepines on urotensin II-stimulated norepinephrine release from rat cerebrocortical slices.2009
- Author(s)
  Kawaguchi Y, Ono T, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Hirota K.
- Journal Title
  
  Anesthesia and Analgesia 108
  
  Pages: 1177-1181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659395
[Journal Article] Orexin A decreases ketamine-induced anesthesia time in the rat : the relevance to brain noradrenergic neuronal activity2009
- Author(s)
  Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
- Journal Title
  
  Anesth Analg 108巻
  
  Pages: 491-495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Role of the orexinergic system in acute haemorrhage in the rat2008
- Author(s)
  Hirota K, Kushikata T, Yoshida H, Kudo M, Kudo T.
- Journal Title
  
  Neurosci Lett 432
  
  Pages: 162-166
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Urotensin II evokes neurotransmitter release from rat cerebrocortical slices2008
- Author(s)
  Ono T, Kawaguchi Y, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Guerrini R, Calo' G, Hirota K
- Journal Title
  
  Neurosci Lett 440(3)
  
  Pages: 275-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659395
[Journal Article] Urotensin II evokes neurotransmitter release from rat cerebrocortical slices2008
- Author(s)
  Ono T, Kawaguchi Y, Kudo M, Kushikata T, Hashiba E,Yoshida H, Kudo T, Furukawa K, Douglas SA, Guerrini R, Calo' G, Hirota K
- Journal Title
  
  Neurosci Lett 440巻
  
  Pages: 275-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Urotensin II evokes neurotransmitter release from rat cerebrocortical slices2008
- Author(s)
  Ono T, Kawaguchi Y, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Guerrini R, Calo G, Hirota K
- Journal Title
  
  Neurosci Lett 440(3)
  
  Pages: 275-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Role of the orexinergic system in acute haemorrhage in the rat.2008
- Author(s)
  Hirota K, Kushikata T, Yoshida H, Kudo M, Kudo T.
- Journal Title
  
  Neurosci Lett 432
  
  Pages: 162-166
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices.2007
- Author(s)
  He Y, Kudo M, Kudo T, Kushikata T, Li E, Hirota K.
- Journal Title
  
  Anesth Analg 104
  
  Pages: 338-340
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices2007
- Author(s)
  He Y, Kudo M, Kudo T, Kushikata T, Li E, Hirota K.
- Journal Title
  
  Anesth Analg 104
  
  Pages: 338-340
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Special cases : ketamine, nitrous oxide and xenon.2006
- Author(s)
  Hirota K, Kudo M, Tose R, et al.
- Journal Title
  
  Best Pract Res Clin Anaesthesiol 20
  
  Pages: 69-79
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Isoflurane increases norepinephrine release in the rat preoptic area and the posterior hypothalamus in vivo and in vitro: Relevance to thermoregulation during anesthesia2005
- Author(s)
  Kushikata T, Hirota K, Kotani N, Yoshida H, Kudo M, Matsuki A.
- Journal Title
  
  Neuroscience 131
  
  Pages: 79-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Isoflurane increases norepinephrine release in the rat preoptic area and the posterior hypothalamus in vivo and in vitro: Relevance to thermoregulation during anesthesia.2005
- Author(s)
  Kushikata T, Hirota K, Kotani N, Yoshida H, Kudo M, Matsuki A.
- Journal Title
  
  Neuroscience 131
  
  Pages: 79-86
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Lack of interaction between orexinergic and alpha2-adrenergic neuronal systems in rat cerebrocortical slices2005
- Author(s)
  Hirota K, Kudo M, Tose R, Yoshida H, Kudo T, Kushikata T.
- Journal Title
  
  Neurosci Lett 387
  
  Pages: 49-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Lack of interaction between orexinergic and α_2-adrenergic neuronal systems in rat cerebrocortical slices.2005
- Author(s)
  Hirota K, Kudo M, Tose R, et al.
- Journal Title
  
  Neuroscience Letters 387
  
  Pages: 49-52
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Lack of interaction between orexinergic and alpha2-adrenergic neuronal systems in rat cerebrocortical slices.2005
- Author(s)
  Hirota K, Kudo M, Tose R, Yoshida H, Kudo T, Kushikata T.
- Journal Title
  
  Neurosci Lett 387
  
  Pages: 49-52
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] オレキシンがケタミンン麻酔に与える影響-ノルアドレナリン作動性神経活性との関連において-.2006
- Author(s)
  遠瀬龍二、櫛方哲也、吉田仁、安田忠伸、工藤美穂子、工藤剛、廣田和美
- Organizer
  第53回日本麻酔科学会総会
- Place of Presentation
  神戸
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] Effects of orexin on ketamine anesthesia. The relation with activity of noradrenergic neurons2006
- Author(s)
  Tose R, Kushikata T, Yoshida H, Yasuda T, Kudo M, Kudo T, Hirota K.
- Organizer
  The 53th Annual Meeting of Japan Society of Anesthesiolohists
- Place of Presentation
  Kobe
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] Plasma orexin A increases by hemorrhagic shock2006
- Author(s)
  Kushikata T, Hirota K, Yoshida H, Tose R, Kudo M.
- Organizer
  The 53th Annual Meeting of Japan Society of. Anesthesiolohists
- Place of Presentation
  Kobe
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] Orexin decreased ketamine anesthesia time in rat. -Relevance to brain noradrenergic neuronal activity2006
- Author(s)
  Tose R, Kushikata T, Yoshida H, Yasuda, Kudo M, Hirota K.
- Organizer
  80th Clinical and Scientific Congress of International A nesthesia Research Society,
- Place of Presentation
  San Francisco
- Year and Date
  2006-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] Orexin decreased ketamine anesthesia time in rat. -Relevance to brain noradrenergic neuronal activity2006
- Author(s)
  Tose R, Kushikata T, Yoshida H, Yasuda, Kudo M, Hirota K.
- Organizer
  80th Clinical and Scientific Congress of International Anesthesia Research Society
- Place of Presentation
  San Francisco
- Year and Date
  2006-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] Effects of nitrous oxide on noradrenaline release from the cerebral cortex in rats2006
- Author(s)
  Yoshida H, Kushikata T, Tose R, Kudo M, Ishihara H, Hirota K.
- Organizer
  The 53th Annual Meeting of Japan Society of Anesthesiolohists
- Place of Presentation
  Kobe
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] 亜酸化窒素の大脳皮質ノルアドレナリン放出に与える影響.2006
- Author(s)
  吉田仁、櫛方哲也、遠瀬龍二、工藤美穂子、石原弘規、廣田和美
- Organizer
  第53回日本麻酔科学会総会
- Place of Presentation
  神戸
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] 出血性ショックは血漿中のオレキシンA(OXA)濃度を増加させる.-オレキシン受容体拮抗薬SB-334867を用いた研究-.2006
- Author(s)
  櫛方哲也、廣田和美、吉田仁、遠瀬龍二、工藤美穂子
- Organizer
  第53回日本麻酔科学会総会
- Place of Presentation
  神戸
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] オレキシンによるラット大脳皮質スライスからの選択的ノルエピネフリン放出に対するベンゾジアゼピンの抑制効果.2005
- Author(s)
  櫛方哲也、工藤美穂子、工藤剛、廣田和美
- Organizer
  第12回日本静脈麻酔・Infusion Technology研究会
- Place of Presentation
  千葉
- Year and Date
  2005-12-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices2005
- Author(s)
  Kushikata T, Kudo M, Kudo T, Hirota K.
- Organizer
  The 12^<th> Japan Society for Intravenous Anesthesia And Infusion Technology
- Place of Presentation
  Chiba
- Year and Date
  2005-12-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423

1. KUDO Mihoko (30003411)

# of Collaborated Projects: 8 results

# of Collaborated Products: 30 results
2. KUSHIKATA Tetsuya (80250603)

# of Collaborated Projects: 4 results

# of Collaborated Products: 28 results
3. HIROTA Kazuyoshi (20238413)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
4. YOSHIDA Hitoshi (00374843)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
5. MATSUKI Akitomo (20003543)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. HASHIMOTO Hiroshi (00218421)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ISHIHARA Hironori (50111224)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MURAOKA Masatoshi (90240647)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SATO Tetsumi (30281934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OYAMA Tsutomu (60003349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 坂井哲博 (80205707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 橋場英二 (10374844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

KUDO Tsuyoshi 工藤 剛

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Studies of Pharmacokinetic on Enatiomers of Ketamine and Norketamine during DFK AnesthesiaPrincipal Investigator

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降圧薬のラット心房性ナトリウム利尿ペプチド(r-ANP)分泌に及ぼす影響Principal Investigator

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Study of the secretion of atrial natriuretic peptide (ANP) induced by morphine.Principal Investigator

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[Journal Article] The Effects of Neuropeptide S on General Anesthesia in Rats2010

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[Journal Article] The Effects of Neuropeptide S on General Anesthesia in Rats2010

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[Journal Article] Interaction between orexinergic neurons and NMDA receptors in the control of locus coeruleus-cerebrocortical noradrenergic activity of the rat2009

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[Journal Article] Interaction between orexinergic neurons and NMDA receptors in the control oflocus coeruleus-cerebrocortical noradrenergic activity of the rat.2009

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[Journal Article] Orexin A decreases ketamine-induced anesthesia time in the rat : the relevance to brain noradrenergic neuronal activity.2009

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KUDO Tsuyoshi 工藤剛