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NAGUMO Masao  南雲 正男

ORCIDConnect your ORCID iD *help
Researcher Number 70013993
Other IDs
External Links
Affiliation (based on the past Project Information) *help 1992 – 2005: 昭和大学, 歯学部, 教授
2000: 昭和大, 歯学部, 教授
1988 – 1990: 昭和大学, 歯学部, 教授
Review Section/Research Field
Principal Investigator
Surgical dentistry / Surgical dentistry / 外科・放射線系歯学
Keywords
Principal Investigator
p21 / 癌化 / MDM2 / oral leukoplakia / 4NQO / 細胞周期 / アポトーシス / ATM / apoptosis / 白板症 … More / carcinogenesis / 口腔白板症 / 上皮異形成 / c-myc / Tunel法 / Ca^<++> influx / myc mRNA / TNF / IFN / 舌粘膜上皮 / MMP / CD44 / PT-PCR / 口腔癌 / mRNA / p53遺伝子欠失マウス / Fas L / Fas / ICAM-1 / 5-Fu / CDDP / P53遺伝子欠失マウス / P21 / epithelial dysplasia / P53 / SNP / 癌遺伝子 / TGF-alpha / 前癌病変 / 遺伝子発現プロファイル / 発癌剤 / マウス / 白血病細胞 / p53 / bcl-2 / Activation of neutrophils / Synergistical effect / Differentiation of Leukemia cell lines / TGF-beta / 活性化の機序 / 好中球 / IL-1 / INF / 分化誘導 / 好〓球活性化 / カルシウムイオン / IFNーγ / 活性化 / 末梢血好中球 / 分化誘導作用 / 好中球の活性化 / 相乗効果 / 白血病細胞の分化 / TGFーβ / marker of malignant transformation / cytokeratin / kallikrein / malignant transformation / gene expression profile / mouse / ヒト白板症 / 遺伝子発プロファイル / マウス口腔粘膜 / 遺伝子プロファイル / 免疫染色 / DNAチップ / 癌化予測マーカー / サイトケラチン遺伝子 / カリクレイン遺伝子 / 上皮性異形成 / p53 independent pathway / carcinogen / wild type mouse / P53 deficient mouse / E2F / Rb / p53非依存性経路 / 発癌物質 / 野生型マウス / Cytokeratin 19 / circulating cancer cell / magnetic bead / metastasis / oral cancer / RT-PCR / 末梢血中細胞 / 局平上皮癌 / サイトケラチン19 / 末稍血中癌細胞 / 磁気ビーズ / 転移 / p53 gene deficient mouse / CDK inhibitors / DNA-PK / CDK阻害因子 / TNF-alpha / caspase / NO donors / IFN-γ / 可溶性Fas / FasL / 5-FU / TNF-α / カスペース / NO供与体 / TUNEL method / p53 knockout mouse / waf1 / cell cycle / cycline dependent kinase / G1 cycline / サイクリン / TUNEL法 / Waf1 / サイクリン依存性キナーゼ / G1サイクリン / oncogene / P53 protein / Le^y antigen / leukoplakia / 異形成 / 遺伝子 / 抗癌剤 / Le^y抗原 / TGF-α / P53蛋白 / Le^Y抗原 / cell proliferation / Langerhans cell / gene expression / cytokines / precancerous lesions / myc / ras / IFN-gamma / HLA-DR抗原 / ウンゲルハンス細胞 / 細胞増殖 / ランゲルハンス細胞 / 遺伝子発現 / サイトカイン / スクリーニング / GeneChipシステム / 遺伝子多型(SNP) / ゲノム / 疾患感受性 / 4-NQO / マウス舌粘膜 / 口腔癌モデル / 免疫遺伝子療法 / SCC抗原作動型 / 遺伝子導入 / PD-1遺伝子 / プロスタグランディン / 増殖抑制 / 舌癌由来扁平上皮癌細胞 / NS-398 / COX-2阻害剤 / G1期 / c-fos / 口腔粘膜上皮 / 遺伝子欠失マウス / Fasリガント / Fas抗原 / 浸潤リンパ球 / 口腔扁平苔癬 Less
  • Research Projects

    (14 results)
  • Co-Researchers

    (10 People)
  •  SNP解析による口腔白板症の疾患関連遺伝子の同定Principal Investigator

    • Principal Investigator
      南雲 正男
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  SCC抗原作動型PD-1-Ig遺伝子を応用した新たな口腔癌免疫遺伝子療法の試みPrincipal Investigator

    • Principal Investigator
      南雲 正男
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Prediction of malignant transformation of oral precancerous lesions by analyzing gene expression profiles and gene polymorphism.Principal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  The participation of p53 independent pathway in the process of oral carcinogenesisPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  COX-2阻害剤による口腔癌の増殖抑制とその機序の解明Principal Investigator

    • Principal Investigator
      南雲 正男
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  The effects of CDK inhibitors and PI3 kinase related kinase on the carcinogenesis from precancerous lesionsPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Development of detection method of metastasis from squamous cell carcinoma of head and neck using peripheral bloodPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  p53遺伝子欠失マウスを用いた口腔癌発症機序の解析Principal Investigator

    • Principal Investigator
      南雲 正男
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Basic research for oral cancer therapy by anti-cancer drugs and apoptosis-inducing factorPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  口腔扁平苔癬における粘膜下リンパ球浸潤の維持機構Principal Investigator

    • Principal Investigator
      南雲 正男
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Cell cycle and apoptosis in the process of carcinogenesis in oral precancerous lesionsPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Apoptosis in the process of carcinogenesis of oral precancerous lesionsPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Changes of cytokines and their gene expression in the process of carcinogenesis of oral precancerous lesionsPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      外科・放射線系歯学
    • Research Institution
      Showa University
  •  Studies of IFN, IL-1, and Tnf on Induction of Differentiation and Activation of Neutrophils.Principal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      外科・放射線系歯学
    • Research Institution
      Showa University
  • 1.  IWASE Masayasu (50193743)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  ITO Daisuke (40286844)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  HATORI Masashi (20245814)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  KAMIJO Ryutaro (70233939)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  OSHIMA Osamu (50167300)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  住谷 要 (70338531)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  YAGAMI Kimitoshi (00210211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YUI Kumie (50317583)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KAKUTA Saburo (40112726)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  桜田 重世 (00112730)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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