Hajime Yasuhara 安原一

… Alternative Names

YASUHARA Hajime 安原一

Less

Researcher Number	70053999
Other IDs
External Links
Affiliation (Current)	2025: 昭和大学, 医学部, 名誉教授
Affiliation (based on the past Project Information) *help	2011 – 2012: 昭和大学, 医学部, 名誉教授 2010: 昭和大学, 医学部, 教授 1994 – 2001: 昭和大学, 医学部, 教授 2000: 昭和大, 医学部, 教授 1989 – 1990: 昭和大学, 医学部, 教授
Review Section/Research Field	Principal Investigator 応用薬理学・医療系薬学 / General pharmacology / Cancer epidemiology and prevention Except Principal Investigator 応用薬理学・医療系薬学
Keywords	Principal Investigator CYP2C19 / Cytochrome P450 / CYP / Trimethadione / Omeprazole / Drug metabolism / in vitro / 薬物代謝 / CYP2E1 / Polymorphism … More / Genotype / Phenotype / Cytochrome P-450 / trimethadione / ラット / 肝薬物代謝酵素 / 肝臓癌 / microsomes / Hepatic cancer / Human liver / 酵素欠損 / 遺伝子欠損 / 肝硬変 / Interaction / Inhibition / Human Liner / Antineoplastic agent / human liver / microsome / 代謝阻害 / ヒト肝ミクロソーム / cytochrome P450 / 阻害作用 / 薬物相互作用 / ヒト肝臓 / 抗悪性腫瘍薬 / Ethics / Chlorzoxazone / Human Liver / Pharmacogenetics / hepatic drug metabolizing enzymes / genetic polymorphism / cytochorome P-450 / omeprazole / 遺伝多型 / Tnimethadione / extrapolation / debrisoquine / antipyrine / model substrates / polymorphism / drug metabolizing enzymes / チトクロ-ムPー450 / エノキサシン / 外挿 / デブリソキン / トリメタジオン / アンチピリン / 指標薬物 / 多様性 / 発がんメカニズム / 遺伝子環境交互作用 / 転移性肝臓癌 / 転移 / サイトカイン / 遺伝子多型 … More Except Principal Investigator microsomes / CYP / Cytochrome P-450 / Drug metabolism / Surgical Samples / Human liver / 薬物代謝 / 手術材料 / cytochrome P450 / ヒト肝臓 Less

Association between genetic polymorphisms of drug-metabolizingenzymes and factors of liver cancerPrincipal Investigator
- Principal Investigator
  
  YASUHARA Hajime
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cancer epidemiology and prevention
- Research Institution
  Showa University
Evaluation of Drug-metabolizing enzyme activity and-drug interaction in paitients with hepatic diseasePrincipal Investigator
- Principal Investigator
  
  YASUHARA Hajime
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  SHOWA UNIVERSITY
Evaluation of reliability of human liver surgical samples from hepatocellular carcinoma and metastatic cancer patients on the application to the drug-metabolism study
- Principal Investigator
  
  KURATA Norimitsu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  SHOWA University
Study of the effects of antineoplastic agents on drug metabolizing enzymes and evaluation of its efficacy and safetyPrincipal Investigator
- Principal Investigator
  
  YASUHARA Hajime
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Showa University
Polymorphism of drug-metabolising enzymesPrincipal Investigator
- Principal Investigator
  
  YASUHARA Hajime
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Showa University
Polymorphism of drug-metabolyzing enzymes and the assessment of drug efficacy and safetyPrincipal Investigator
- Principal Investigator
  
  YASUHARA Hajime
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Showa University
Polymorphism of Hepatic Dung Metabolizing Enzymes and Extrapolation of its Data from Animal to HumanPrincipal Investigator
- Principal Investigator
  
  YASUHARA Hajime
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Showa University

All 2011

All Presentation

[Presentation] CYP2C19遺伝子変異の発癌への関与2011
- Author(s)
  西村有希、倉田知光、岩瀬万里子、小林靖奈、山元俊憲、安原一
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-24
- Data Source
  KAKENHI-PROJECT-22501059
[Presentation] CYP2C19遺伝子変異と肝臓癌発症リスクの関連2011
- Author(s)
  西村有希、倉田知光、岩瀬万里子、安原一、小林靖奈、山元俊憲、青木武士、村上雅彦、齋藤光次、小林真一
- Organizer
  第32回日本臨床薬理学会年会
- Place of Presentation
  浜松
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-22501059

1. KURATA Norimitsu (80231299)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
2. NISHIMURA Yuki (40276572)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. UCHIDA Eiji (80175223)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. IWASE Mariko (70424273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. UEDA Takako (00175499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KOBAYASHI Shinichi (20129836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hajime Yasuhara 安原 一

YASUHARA Hajime 安原 一

Research Projects

Research Products

Co-Researchers

Association between genetic polymorphisms of drug-metabolizingenzymes and factors of liver cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of Drug-metabolizing enzyme activity and-drug interaction in paitients with hepatic diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of reliability of human liver surgical samples from hepatocellular carcinoma and metastatic cancer patients on the application to the drug-metabolism study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of the effects of antineoplastic agents on drug metabolizing enzymes and evaluation of its efficacy and safetyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Polymorphism of drug-metabolising enzymesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Polymorphism of drug-metabolyzing enzymes and the assessment of drug efficacy and safetyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Polymorphism of Hepatic Dung Metabolizing Enzymes and Extrapolation of its Data from Animal to HumanPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Presentation] CYP2C19遺伝子変異の発癌への関与2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] CYP2C19遺伝子変異と肝臓癌発症リスクの関連2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Hajime Yasuhara 安原一

YASUHARA Hajime 安原一