TAMAYA Teruhiko 玉舍輝彦

Researcher Number	70079870
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2005 : Gifu University, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授 2004 : Gifu Univ., OB/GYN., Prof, 大学院・医学研究科, 教授 1987 – 2003 : 岐阜大学, 医学部, 教授 1986 : 京府医大, 医学部, 助教授
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator 子宮内膜 / エストロゲン / 子宮内膜癌 / GnRH / GnRH作用 / 植物性エストロゲン / 子宮 / PTEN / マウス / SHBG … More Except Principal Investigator 子宮内膜癌 / 卵巣癌 / 女性生殖器癌 / mRNA / ゴナドトロピン放出因子 / GnRH / 血管新生因子 / 子宮内膜症 / 浸潤・転移 / c-fos / RT-PCR / Fas / VEGF / ゴナドトロピン / 顆粒膜細胞 / 増殖因子 / basic FGF / ウエスタンブロッティング / PTEN / tumor dormancy therapy / Apoptosis / Endometrial cancer / 転写因子 / 血管新生 / GnRH II / GnRH receptor / 婦人科癌 / female genital tract cancers / 分子生物学 / 血管新生阻害薬 / アポトーシス / 受容体占有 / GnRH受容体 / 遺伝子変異 / エストロゲン受容体 / jun / TNF-α / ゴナドトロピン放出因子受容体 / Ser / metastasis / IL-1α / エストロゲン / PD-ECGF / 転移 / 腫瘍休眠療法 / angiogenic factors / angiogenesis / 性ステロイド / カドヘリン / エストロゲン合成 / Endometrial carcinoma / Giファミリー / Uterine Endometrial Cancer / CPT-11 / Thrホスファターゼ / 遺伝子発現 / Receptor occupancy / Ovarian carcinoma / gonadotropin / splicing variants / receptors / invasion and metastasis / 卵巣機能 / FGF / プロゲステロン受容体 / mutation / イノシト-ルリン脂質 / オートクリン調節 / anti-proliferative activity / 遺伝子組み換えアデノウイルス / 燐酸化 / アンドロゲン受容体 / 脱リン酸化酵素 / Tyrosine kinase C / angiogenic inhibitor / Mice / Chemoprevention / ウエスタンプロッティング / アデノウイルスベクター / Ovarian cancer / paclitaxel / セカンドメッセンジャ- / イソフラボン / Endometrium / Gi蛋白質 / DNA topoisomerase / 化学予防 / プロゲスチン / Gonadotropin / Ovaian Cancer / cell lines / 子宮内膜 / 癌遺伝子 / Gタンパク / 癌増殖 / 核内受容体 / マウス / 抗癌化学療法 / estrogen receptor / 発癌抑制 / 膜現象 / プレGnRH / 細胞増殖 / ギャップ・ジャンクション / Isoflavones / endometriosis / angiogenic inhibitors / 性スラロイド・レセプター / Thr phosphatase / Fas ligand / Gn-RH receptor / DNA topoisomerase I / transcription factors / Ovary / 子宮筋腫 / Gn-RH / angiogenic factor / Hormone-therapy / Oncogenes / 内分泌撹乱化学物質 / エンドペプチダーゼ / 抗ステロイド / (1-5)GnRH / Gonadotropin-releasing hormone / GTP結合蛋白質 / Molecular Biology / ダイゼイン / GTP-binding protein / 血管新生阻害剤 / カルシウムイオン / オートクリン機構 / 培養細胞 / 受容体 / estrogen synthesis / Molecular biology / growth factor / 酵素の細胞内再分布 / イノシト-ル三リン酸 / Fasリガント / Fasリガンド / camptotecin / Estroqens / Uterine Leiomyoma / gynecological cancers / Granulosa cell / プロセッシング異常 / endometrail carcinoma / 内分泌攪乱化学物質 / Cancer cell lines / 化学療法 / PAI-1 / Estrogen / adenoviral vector / フォスファターゼ / 悪性腫瘍 / メッセンジャーRNA / Western blotting / angiogenisis / TNP470 / 内分泌攪乱物質 / イノシトールリン脂質 / 内分泌関与 / growth factors / camptothecin / 明細胞腺癌 / E-カドヘリン / サイトカイン / Chemotherapy / 抗腫瘍効果 / チロシン・チナーゼ / リゾポスファチジン酸 / コネキシン43 / アロマタ-ゼ / steroid receptors / ゲニステイン / transcription factor / clear cell carcinoma (6) / endocrine disruptors / Aromatase / 子宮頚癌 / 受容・応答機構 / Phosphoinositide / 卵単癌 / Protein kinase C / Camptothecin / protein Kinase / ProGnRH II / DNAトポイソメラーゼ / チロシンリン酸化 / プロGnRH II / Sex Steroid Receptors / 卵巣 / プロラインキナーゼC / Cytokines / sex steroids Less

Angiogenesis and tumor dormancy therapy in gynecological cancer
- Principal Investigator
  
  FUJIMOTO Jiro
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
Involvement of PTEN in hormone-dependent proliferation of endometrial ocarcinoma cells
- Principal Investigator
  
  YOKOYAMA Yasuhiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
オーファンレセプター、エストロゲン関連レセプター(ERR)の研究-リガンド検出とERRの生物学的作用への環境汚染物質の影響-Principal Investigator
- Principal Investigator
  
  玉舎輝彦
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
Mecliamisms of cellelar proliferation and its control in hormonal regulation of gynecological tumors.Principal Investigator
- Principal Investigator
  
  TAMAYA Teruhiko
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
BASIC RESEARCH OF THE GENE THERAPY FOR ENDOMETRIOSIS
- Principal Investigator
  
  ITO Naoki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
Alternative gonadotropin-releasing hormone I and II processing products secreted from endometrial carcinoma
- Principal Investigator
  
  IMAI Atsushi
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
Studies on inhibitory effects of isoflavones on endometrial carcinogenesis.
- Principal Investigator
  
  NIWA Kenji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
Angiogenesis in female genital tract cancers and its inhibition
- Principal Investigator
  
  FUJIMOTO Jiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
植物エストロゲンの子宮内膜癌発生・発育の予防Principal Investigator
- Principal Investigator
  
  玉舎輝彦
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
The study on the cellular growth and its regulation in female reproductive organs and related tumors, with the reference of sex-steroidsPrincipal Investigator
- Principal Investigator
  
  TAMAYA Teruhiko
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  GIFU UNIVERSITY
Study of endocrinological contribution for invasion and metastasis in gynecological cancers
- Principal Investigator
  
  FUJIMOTO Jiro
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
Pathophysiology of GTP-binding protein-linked receptors in hormone-sensitive tumors
- Principal Investigator
  
  IMAI Atsushi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
Study of mechanisms of development and growth in hormone (especially estrogen) dependent uterine tumor and its related diseases.
- Principal Investigator
  
  FUJIMOTO Jiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University School of Medicine
Studies on development and proliferation of endometrial cancer from sex steroid receptor and oncogenesPrincipal Investigator
- Principal Investigator
  
  TAMAYA Teruhiko
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  GIFU UNIVERSITY
Studies on DNA topoisomerase-targeted anti-cancer chemotherapy in gynecologic malignancy.
- Principal Investigator
  
  NIWA Kenji, 森秀弘
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  GIFU UNIVERSITY
Physiological role and transmembranesignaling of gonadotropin-releasing hormonein granulosa cells : expression of Gn-RH and its receptor in the ovary
- Principal Investigator
  
  IMAI Atsushi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
Biological and clinical aspects of estrogen receptor-related evidencesPrincipal Investigator
- Principal Investigator
  
  TAMAYA Teruhiko
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
Physiological role of gonadotropin-releasing hormone (LH-RH) on ovarian function ; phosphoinositide metabolism in granulosa cells.
- Principal Investigator
  
  IMAI Atsushi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
Biological implication and clinical aspect of sex steroid receptorsPrincipal Investigator
- Principal Investigator
  
  TAMAYA Teruhiko
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Gifu University
  Kyoto Prefectural University of Medicine

All 2006 2005 2004 2003 2002

All Journal Article

[Journal Article] Clinical implications of expression of cyclooxygenase-2 related to angiogenesis in ovarian cancer.2006
- Author(s)
  Fujimoto J, Toyoki H, Sakaguchi H, Jahan I, Alam SM, Tamaya T
- Journal Title
  
  Oncol Rep 2006 15
  
  Pages : 21-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] Clinical implications of expression of cyclooxygenase-2 related to angiogenesis in uterine endometrial cancers.2005
- Author(s)
  Toyoki H, Fujimoto J, Sato E, Sakaguchi H, Tamaya T
- Journal Title
  
  Ann Oncol 16
  
  Pages : 51-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] PTEN Sensitizes Epidermal Growth Factor-Mediated Proliferation in Endometrial Carcinoma Cells.2005
- Author(s)
  Liulin Tang, Yasuhiro Yokoyama, Xiaoyun Wan, Shigenori Iwagaki, Teruhiko Tamaya.
- Journal Title
  
  Oncology Report (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571552
[Journal Article] PTEN Sensitizes Epidermal Growth Factor-Mediated Proliferation in Endometrial Carcinoma Cells.2005
- Author(s)
  Liulin Tang, Yasuhiro Yokoyama, Xiaoyun Wan, Shigenori Iwagaki, Teruhiko Tamaya
- Journal Title
  
  Oncology Report (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571552
[Journal Article] Sex steroid-dependent angiogenesis in uterine endometrial cancers2005
- Author(s)
  Fujimoto J, Toyoki H, Jahan I, Alam SM, Sakaguchi H, Sato E, Tamaya T
- Journal Title
  
  J Steroid Biochem Mol Biol 93
  
  Pages : 161-165
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] Expression of E26 transformation specific (ETS-1) related to angiogenesis in ovarian endometriosis.2004
- Author(s)
  Sakaguchi H, Fujimoto J, Aoki I, Toyoki H, Sato E, Tamaya T
- Journal Title
  
  Fertil Steril 82
  
  Pages : 507-510
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] Preventive effect of Juzen-taiho-to on endometrial carcinogenesis in mice is based on Shimotsu-to constituent.2004
- Author(s)
  Niwa K, Tamaya T et al.
- Journal Title
  
  Biol Pharm Bull 27
  
  Pages : 156-161
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470351
[Journal Article] Evidence for tight coupling of Gi protein-mediated lysophosphatidic acid receptor to stimulated cytokine production in ovarian cancer cell.2004
- Author(s)
  Sugiyama M, Tamaya T et al.
- Journal Title
  
  Am Obstet Gynecol 190
  
  Pages : 680-685
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470351
[Journal Article] Clinical implication of expression of vascular endothelial growth factor-C in metastatic lymph nodes of uterine cervical cancers.2004
- Author(s)
  Fujimoto J, Toyoki H, Sato E, Sakaguchi H, Tamaya T
- Journal Title
  
  Br J Cancer 91
  
  Pages : 466-469
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] Clinical implications of expression of ETS-1 related to angiogenesis in metastatic lesions of ovarian cancers.2004
- Author(s)
  Fujimoto J, Aoki I, Toyoki H, Khatun S, Sato E, Sakaguchi H, Tamaya T
- Journal Title
  
  Oncology (Basel) 66
  
  Pages : 420-428
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] Placental growth by the estrogen-dependent angiogenic factors vascular endothelial growth factor and basic fibroblast growth factor throughout gestation.2004
- Author(s)
  Nakagawa Y, Fujimoto J, Tamaya T
- Journal Title
  
  Gynecol Endocrinol 19
  
  Pages : 259-266
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] Evidence for tight coupling of Gi protein-mediated lysophosphatidic acid receptor to stimulated cytokine production in ovarian cancer cell2004
- Author(s)
  Sugiyama M, Tamaya T et al.
- Journal Title
  
  Am Obstet Gynecol 190
  
  Pages : 680-685
- Data Source
  KAKENHI-PROJECT-13470351
[Journal Article] Independent action of serine/threonine protein phosphatase in ovarian cancer plasma membrane and cytosol during gonadotropin-releasing hormone stimulatin.2003
- Author(s)
  Sugiyama M, Tamaya T et al.
- Journal Title
  
  Oncol Rep 10
  
  Pages : 1885-1889
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470351
[Journal Article] Expression of ETS-1 related to angiogenosis in uterine endometrium during the menstrual cycle.2003
- Author(s)
  Fujimoto J, Aoki I, Toyoki H, Khatun S, Sato E, Tamaya T
- Journal Title
  
  J Biomed Sci 10
  
  Pages : 320-327
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] Expression of estrogen receptor β exon-deleted variant mRNAs in ovary and uterine endometrium.2003
- Author(s)
  Fujimoto J, Tamaya T et al.
- Journal Title
  
  Steroid Biochem Molec Biol 84
  
  Pages : 133-140
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470351
[Journal Article] Clinical implications of expression of ETS-1 in relation to angiogenosis in ovarian cancers.2003
- Author(s)
  Khatun S, Fujimoto J, Toyoki H, Tamaya T
- Journal Title
  
  Cancer Sci (Jpn J Cancer Res) 1
  
  Pages : 769-773
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] Various steroids on platelet-derived endothelial cell growth factor (PD-ECGF) and its mRNA expression in uterine endometrial cancer cells.2003
- Author(s)
  Aoki I, Fujimoto J, Tamaya T
- Journal Title
  
  J Steroid Biochem Mol Biol 84
  
  Pages : 217-222
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] Coexprssion of growth arrest-specific gene 6 and receptor tyrosine kinases Axl and Sky in human uterine endometrial cancers.2003
- Author(s)
  Sun W, Tamaya T et al.
- Journal Title
  
  Ann Oncol 14
  
  Pages : 898-906
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470351
[Journal Article] Clinical implications of expression of interleukin-8 related to myometrial invasion with angiogenosis in uterine endometrial cancers.2002
- Author(s)
  Fujimoto J, Aoki I, Khatun S, Toyoki H, Tamaya T
- Journal Title
  
  Ann Oncol 13
  
  Pages : 430-434
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] Clinical implications of expression of ETS-1 related to angiogenosis in uterine endometrial cancers.2002
- Author(s)
  Fujimoto J, Aoki I, Toyoki H, Khatun S, Tamaya T
- Journal Title
  
  Ann Oncol 13
  
  Pages : 1605-1611
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528
[Journal Article] Divalent hammerthead ribozyme targeting template region of human telomerase RNA has potent cleavage activity, but less inhibitory activity on telomerase.2002
- Author(s)
  Yokoyama Y, Tamaya T et al.
- Journal Title
  
  Arch Biochem Biophys 405
  
  Pages : 32-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470351
[Journal Article] Clinical implications of expression of ETS-1 related to angiogenosis in uterine cervical cancers.2002
- Author(s)
  Fujimoto J, Aoki I, Toyoki H, Khatun S, Tamaya T
- Journal Title
  
  Ann Oncol 13
  
  Pages : 1598-1604
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370528

1. FUJIMOTO Jiro (80199372)

# of Collaborated Projects : 9results

# of Collaborated Products : 14results
2. IMAI Atsushi (40193643)

# of Collaborated Projects : 8results

# of Collaborated Products : 0results
3. NIWA Kenji (80218247)

# of Collaborated Projects : 6results

# of Collaborated Products : 1results
4. ITO Naoki (30184675)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
5. YOKOYAMA Yasuhiro (00200923)

# of Collaborated Projects : 3results

# of Collaborated Products : 3results
6. 森秀弘 (50190997)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
7. MISAO Ryo (40262761)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. FURUI Tatsuro (00313883)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. 高橋雄一郎 (50334925)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

TAMAYA Teruhiko 玉舍 輝彦

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オーファンレセプター、エストロゲン関連レセプター(ERR)の研究-リガンド検出とERRの生物学的作用への環境汚染物質の影響-Principal Investigator

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Mecliamisms of cellelar proliferation and its control in hormonal regulation of gynecological tumors.Principal Investigator

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植物エストロゲンの子宮内膜癌発生・発育の予防Principal Investigator

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The study on the cellular growth and its regulation in female reproductive organs and related tumors, with the reference of sex-steroidsPrincipal Investigator

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Studies on development and proliferation of endometrial cancer from sex steroid receptor and oncogenesPrincipal Investigator

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TAMAYA Teruhiko 玉舍輝彦