OBARA Takao 小原孝男

… Alternative Names

小原孝男オバラタカオ

Less

Researcher Number	70090488
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2004 – 2006: Tokyo Women's Medical University, Professor, 医学部, 教授 1998 – 1999: 東京女子医科大学, 医学部, 教授 1995 – 1996: 東京女子医科大学, 医学部, 教授 1988: Tokyo Women's Medical College, Department of Endocrine Surgery, 医学部内分泌外科, 助教授 1987 – 1988: 東京女子医科大学, 医学部・内分泌外科, 助教授 1986: Tokyo Women's Medical College, Department of Endocrine Surgery, 医学部, 助教授
Review Section/Research Field	Principal Investigator General surgery Except Principal Investigator Endocrinology / General surgery / Radiation science
Keywords	Principal Investigator 上皮小体癌 / 原発性上皮小体機能亢進症 / Parathyroid carcinoma / Primary hyperparathyroidism / 原発性副甲状腺機能亢進症 / ビタミンD受容体遺伝子多型 / 骨密度 / 血管内皮細胞増殖因子 / 甲状腺濾胞癌 / 甲状腺乳頭癌 … More / 転移 / 甲状腺癌 / 血管内皮細胞増殖増殖因子 / 発癌機序 / vascular endothelial growth factor / papillary thyroid carcinoma / follicular thyroid carcinoma / metastasis / 高カルシウム血症 / DNAヒストグラム / 上皮小体癌の部位診断法 / 上皮小体癌の抗癌剤療法 / dacarbazine / Hypercalcemia / Flowcytometric DNA analysis / Localization study for recurrent parathyroid carcinoma / 上皮小体腺腫 / 上皮小体過形成 / flowcytometry / aneuploidy / flow cytometry / DNAdiploid / DNAaneuploid / Parathyroid adenoma / Primary hyperplasia / Flowcytometry … More Except Principal Investigator Dosimetry / Functioning mass volume / Thyroid cancer / Radioisotope therapy / Grave's disease / cDNA microarray / prion / double-stranded RNA / 甲状腺乳頭癌 / 接着分子 / E-カドヘリン / 病理組織学 / Radioisotope / Graves disease / Dosimetyr / 副甲状腺 / リン(phosphate) / 副甲状腺ホルモン(PTH) / 成長因子 / 副甲状腺機能亢進症 / 高リン血症 / cDNA minoarray / 細胞増殖刺激因子 / parathyroid gland / phosphate / PTH / growth factors / Toll-like receptor 3 / 1型インターフェロン / 甲状腺濾胞細胞 / 亜急性甲状腺炎 / 血管内皮細胞増殖因子 / 甲状腺血流量 / 無機ヨード / Interferon-α / interferon-β / DNA microarray / Toll-like receptor-3 / type I interferon / thyroid follicles / subacute thyroiditis / vascular endothelial growth factor / thyroidal blood flow / inorganic iodide Less

Endocrinological and Immunological Roles of Toll-like Receptor 3 in Culture Human Thyroid Follicles
- Principal Investigator
  
  SATO Kanji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Tokyo Women's Medical University
GENES REGULATED BY PHOSPHATE-INDUCED PARATHYROID CELL PROLIFERATION IN ORGAN CULTURE : ANALYSIS USING OLIGO-DNA MICROARRAY
- Principal Investigator
  
  SATO Kanji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Tokyo Women's Medical University
The volumetric methods in the lesions for radioisotope therapy
- Principal Investigator
  
  KUSAKABE Kiyoko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Tokyo Women's Medical University
Vascular endothelial growth factor-C mRNA expression on lymphatic metastasis of thyroid papillary carcinomaPrincipal Investigator
- Principal Investigator
  
  OBARA Takao
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Women's Medical University
原発性副甲状腺機能亢進症患者のビタミンD受容体遺伝子多型と骨密度および手術適応Principal Investigator
- Principal Investigator
  
  小原孝男
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Women's Medical University
甲状腺乳頭癌における接着分子および裏うち蛋白の発現異常と生物学的悪性度の関連
- Principal Investigator
  
  山下共行
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Women's Medical University
Flow-cytometric DNA analysis for pathological diagnosis of parathyroid carcinoma.Principal Investigator
- Principal Investigator
  
  OBARA Takao
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Women's Medical College
Parathyroid carcinoma:Criteria for the diagnosis and appropriate therapy of recurrence.Principal Investigator
- Principal Investigator
  
  OBARA Takao
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Women's Medical College

All 2007 2006 2004 2003 2001 Other

All Journal Article

[Journal Article] Suppression of iodide uptake and thyroid hormone synthesis with stimulation of type I interferon system by double-stranded RNA (dsRNA) in cultured human thyroid follicles2007
- Author(s)
  Yamazaki K, Suzuki K, Emiko Yamada E, Yamada T, Takeshita F, Matsumoto M, Mitsuhashi T, Obara T, Takano K, Sato K
- Journal Title
  
  Endocrinology 148 (In revision)
- Data Source
  KAKENHI-PROJECT-17590967
[Journal Article] Suppression of iodide uptake and thyroid hormone synthesis with stimulation of type I interferon system by double-stranded RNA (dsRNA) in cultured human thyroid follicles2007
- Author(s)
  Yamazaki K, Suzuki K, Yamada E, Yamada T, Takeshita F, Matsumoto M, Mitsuhashi T, Obara T, Takano K, Sato K
- Journal Title
  
  Endocrinology 148(In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590967
[Journal Article] Iodide inhibits vascular endothelial growth factor (VEGF)-A expression in cultured human thyroid follicles : a microarray search for effects of TSH and iodide on angiogenesis factors2006
- Author(s)
  Yamada E, Yamazaki K, Takano K, Obara T, Sato K
- Journal Title
  
  Thyroid 16
  
  Pages: 545-554
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590967
[Journal Article] 「研究成果報告書概要(欧文)」より2006
- Author(s)
  Yamada E, Yamazaki K, Takano K, Obara T, Sato K
- Journal Title
  
  Iodide inhibits vascular endothelial growth factor (VEGF)-A expression in cultured human thyroid follicles : a microarray search for effects of TSH and iodide on angiogenesis factors. Thyroid 16
  
  Pages: 545-554
- Data Source
  KAKENHI-PROJECT-17590967
[Journal Article] Hypercalcemia induced by excessive intake of calcium supplement, presenting similar findings of primary hyperparathyroidism.2004
- Author(s)
  Kato Y, Sato K, Sata A, Omori K, Nakajima K, Tokinaga K, Obara T, Takano K.
- Journal Title
  
  Endocr J 51
  
  Pages: 557-562
- NAID
  10014080474
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590985
[Journal Article] Genes regulated by TSH and iodide in cultured human thyroid follicles : Analysis by cDNA microarray2003
- Author(s)
  Yamazaki K, Yamada E, Obara T, Sato K.
- Journal Title
  
  Thyroid 13
  
  Pages: 149-158
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590985
[Journal Article] Genes regulated by TSH and iodide in cultured human thyroid follicles : Analysis by cDNA microarray2003
- Author(s)
  Yamazaki K, Yamada E, Obara T, Sato K
- Journal Title
  
  Thyroid 13
  
  Pages: 149-158
- Data Source
  KAKENHI-PROJECT-15590985
[Journal Article] Genes Regulated by TSH and iodide in cultured human thyroid follicles : analysis by cDNA microarray.2003
- Author(s)
  Yamazaki Y, Yamada E, Kanaji Y, Yanagisawa T, Kato Y, Takano K, Obara T, Sato K.
- Journal Title
  
  Thyroid 13
  
  Pages: 149-158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590985
[Journal Article] Somatic mutations of the MEN-1 gene and microsatellite instability in tertiary hyperparathyroidism occurring during high phosphate therapy for acquired, hypophosphatemic osteomalacia2001
- Author(s)
  Sato K, Obara T, Yamazaki, Nakajima K, et al.
- Journal Title
  
  J. Clin Endocrinol.Metab 86
  
  Pages: 5564-5571
- Data Source
  KAKENHI-PROJECT-15590985
[Journal Article] Somatic mutations of the MEN-1 gene and microsatellite instability in tertiary hyperparathyroidism occurring2001
- Author(s)
  Sato K, Obara T, Yamazaki K, Nakajima K, et al.
- Journal Title
  
  J.Clin Endocrinol.Metab 86
  
  Pages: 5564-5571
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590985
[Journal Article] Somatic mutations of the MEN1 gene and microsatellite instability in tertiary hyperparathyroidism occurring during high phosphate therapy for acquired, hypophosphatemic osteomalacia2001
- Author(s)
  Sato K, Obara T, Yamazaki K, Kanbe M, Nakajima K, Yamada A, Yanagisawa T, Kato Y, Nishikawa T, Takano K.
- Journal Title
  
  J Clin Endocrinol Metab 86
  
  Pages: 5564-5571
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590985
[Journal Article] Phosphate-induced proliferation in parathyroid cells obtained from primary and secondary hyperparathyroidism
- Author(s)
  Nakajima K, Takano K, Obara T., Sato K
- Journal Title
  
  J Bone Miner Res (submitted)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590985
[Journal Article] Phosphate-induced proliferation in parathyroid cells obtained from primary and secondary hyper para ---
- Author(s)
  Nakajima K, Takano K, Obara T, Sato K
- Journal Title
  
  J.Bone Miner Res. (Submitted)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590985
[Journal Article] Phosphate-induced proliferation in parathyroid cells obtained from primary and secondary hyperpara
- Author(s)
  Nakajima K, Takano K, Obara T, Sato K
- Journal Title
  
  J.Bone Miner Res (submitted)
- Data Source
  KAKENHI-PROJECT-15590985

1. SATO Kanji (60138857)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
2. KUSAKABE Kiyoko (80075473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. IIHARA Masatoshi (10222829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. OKAMOTO Takahiro (70194397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TANAKA Reiko (60197499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SUZUKI Koichi (20206478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. HIRAYAMA Akira (80075217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KODAMA Takaya (30161946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. FUJIMOTO Yoshihide (10010167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山下共行 (60174679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 神戸雅子 (90214733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OBARA Takao 小原 孝男

小原 孝男 オバラ タカオ

Research Projects

Research Products

Co-Researchers

Endocrinological and Immunological Roles of Toll-like Receptor 3 in Culture Human Thyroid Follicles

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GENES REGULATED BY PHOSPHATE-INDUCED PARATHYROID CELL PROLIFERATION IN ORGAN CULTURE : ANALYSIS USING OLIGO-DNA MICROARRAY

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The volumetric methods in the lesions for radioisotope therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Vascular endothelial growth factor-C mRNA expression on lymphatic metastasis of thyroid papillary carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

原発性副甲状腺機能亢進症患者のビタミンD受容体遺伝子多型と骨密度および手術適応Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

甲状腺乳頭癌における接着分子および裏うち蛋白の発現異常と生物学的悪性度の関連

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Flow-cytometric DNA analysis for pathological diagnosis of parathyroid carcinoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Parathyroid carcinoma:Criteria for the diagnosis and appropriate therapy of recurrence.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Suppression of iodide uptake and thyroid hormone synthesis with stimulation of type I interferon system by double-stranded RNA (dsRNA) in cultured human thyroid follicles2007

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of iodide uptake and thyroid hormone synthesis with stimulation of type I interferon system by double-stranded RNA (dsRNA) in cultured human thyroid follicles2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Iodide inhibits vascular endothelial growth factor (VEGF)-A expression in cultured human thyroid follicles : a microarray search for effects of TSH and iodide on angiogenesis factors2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] 「研究成果報告書概要(欧文)」より2006

Author(s)

Journal Title

Data Source

[Journal Article] Hypercalcemia induced by excessive intake of calcium supplement, presenting similar findings of primary hyperparathyroidism.2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Genes regulated by TSH and iodide in cultured human thyroid follicles : Analysis by cDNA microarray2003

Author(s)

Journal Title

OBARA Takao 小原孝男

小原孝男オバラタカオ