HISHIDA Akira 菱田名

Researcher Number	70111812
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2010: 浜松医科大学, 医学部, 教授 2008: 浜松医科大学, 医学部, 教授 2004: HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE, professor, 医学部, 教授 1999 – 2004: 浜松医科大学, 医学部, 教授 1998: 浜松医科大学, 医学部, 助教授 … More 1996: Hamamatsu University School of Medicine, Department of Medicine, Associate Professor, 医学部附属病院, 助教授 1995 – 1996: 浜松医科大学, 医学部, 助教授 1992 – 1993: 浜松医科大学, 医学部, 助教授 1988 – 1989: 浜松医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / 内科学一般 / Kidney internal medicine / Fisheries chemistry Except Principal Investigator Kidney internal medicine / 内科学一般 / Kidney internal medicine
Keywords	Principal Investigator p21 / acute renal failure / 急性腎不全 / p27 / シスプラチン / DNA修復 / アポトーシス / IGF-1 / サイクリンD_1 / DNA repair … More / p53 / cisplatin / 細胞周期 / apoptosis / aminonucleoside nephrosis / cuprolinic blue / proteoglycan / anionic charge barrier / glomerular basement membrane / ネフローゼ / ネフロ-ゼ / プロテオグリカン / 荷電障壁 / 透過性 / 糸球体基底膜 / GADD45 / p21 antisense / cyclinB1 / cyclineD1 / GADD153 / サイクリンB_1 / アンチセンス / 近位尿細管 / 腎皮質 / sodium arsenite / cyclin D1 / csplatin / 急性腎不全に対する抵抗性獲得 / 細胞周期調節 / 砒素 / 細胞周期調節因子 / cell cycle / BC12 / グリシン / 活性酸素 / rechallenged injury / uninephrectomy / tubular regeneration / uranyl acetate / ischemia / 虚血性腎障害 / 細胞増殖 / 再侵襲 / 片腎摘出 / 尿細管再生 / 酢酸ウラニウム / 虚血 / thromboxane / endothelin / nephrectomy / イヌリンクリアランス / 虚血性急性腎不全 / PCNA / トロンボキサン / エンドセリン / 腎摘出 … More Except Principal Investigator mycophenolate mofetil / 急性腎不全 / cast formation / tubular necrosis / glomerular filtering surface area / oliguric acute renal failure / nonoliguric acute renal failure / 尿細管壊死 / 糸球体有効濾過面積 / ウラニウム誘発急性腎不全 / 虚血性急性腎不全 / 非乏尿性急性腎不全 / uranyl acetate / cellular fibronectin / macrophage / alpha-smooth muscle actin / myofibroblast / acute renal failure / ミィオフィブロブラスト / 尿細管増殖 / 尿細管細胞 / ミコフェノール酸モフュチル / 細胞性フィブロネクチン / 酢酸ウラニウム / ミユフェノール酸モフェチル / 細胞性フィブロブラスト / マクロファージ / α平滑筋アクチン / ミオフィブロブラスト / 閉塞性腎障害 / プロレニン受容体 / 慢性腎臓病 / 塩分摂取 / (プロ)レニン受容体 / レニン / アンジオテンシン / 腎線維化 / プロレニン / 高塩分 / レニン・アンジオテンシン系 / がん / 腎障害 / NFκB / シスプラチン / 細胞・組織 / 再生医学 / 修復 / 前駆様細胞 / 再生 / 近位尿細管細胞 / 尿細管 Less

Effect of salt load on the intrarenal angiotensin activity and receptor-mediated prorenin system in kidney fibrosis
- Principal Investigator
  
  YAMAMOTO Tatsuo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hamamatsu University
Roles of progenitor-like cells and infiltrative macrophages on renal tubular regeneration and their application on cell therapy
- Principal Investigator
  
  FUJIGAKI Yoshihide
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hamamatsu University School of Medicine
Dual effects of NFκB inhibitors on viability of cancer and kidney induced by cisplatin
- Principal Investigator
  
  YASUDA Hideo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hamamatsu University School of Medicine
The prevention of acute renal failure through the intervention in the DNA repair system.Principal Investigator
- Principal Investigator
  
  HISHIDA Akira
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
The role of p21, a cell cycle regulation factor, in the development of cisplatin-induced acute renal failurePrincipal Investigator
- Principal Investigator
  
  HISHIDA Akira
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hamamatsu University School of Medicine
Roles of interstitial cells on the recovery process from acute renal failure
- Principal Investigator
  
  FUJIGAKI Yoshihide
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hamamatsu University, School of Medicine
The role of apoptosis in cisplatin-induced acute renal failure.Principal Investigator
- Principal Investigator
  
  HISHIDA Akira
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hamamatsu University School of Medicine.
The study on the factors which enhance the recovery from acute renal failure.Principal Investigator
- Principal Investigator
  
  HISHIDA Akira
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hamamatsu university School of Medicine
The roles of endothelin and growth factors in ischemic acute renal failure.Principal Investigator
- Principal Investigator
  
  HISHIDA Akira
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Hamamatsu University School of Medicine
Pathogenesis of nonoliguric acute renal failure.
- Principal Investigator
  
  HONDA Nishio
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Hamamatsu University School of Medicine
The role of anionic charge of the glomerular basement membrane.Principal Investigator
- Principal Investigator
  
  HISHIDA Akira
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Hamamatsu University School of Medicine

All 2010 2009 2008 2007 2004

All Journal Article Presentation

[Journal Article] Reduction of transforming growth factor-β type II receptor is caused by the enhanced ubiquitin-dependent degradation in human renal cell carcinoma2010
- Author(s)
  Fukasawa H, Yamamoto T, Fujigaki Y, Misaki T, Ohashi N, Takayama T, Mugiya S, Oda T, Uchida C, Kitagawa K, Hattori T, Suzuki S, Hayashi H, Ozono S, Kitagawa M, Hishida A
- Journal Title
  
  Int.J.Cancer 127
  
  Pages: 1517-1525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590967
[Journal Article] Cell division and phenotype regression of proximal tubular cells in response to uranyl acetate insult in rats2009
- Author(s)
  Fujigaki Y, Sakakima M, M, Sun Y, Fujikura T, Tsuji T, Yasuda H, Hishida A
- Journal Title
  
  Nephrol Dial Transplant
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590945
[Journal Article] The dimethylthiourea-induced attenuation of cisplatin nephrotoxicity is associated with the augmented induction of heat shock proteins2009
- Author(s)
  Tsuji T, Kato A, Yasuda H, Miyaji T, Luo J, Sakao Y, Ito H, Fujigaki Y, Hishida A
- Journal Title
  
  Toxicol Appl Pharmacol 234
  
  Pages: 202-8
- Data Source
  KAKENHI-PROJECT-19790579
[Journal Article] Decrease in tumor necrosis factor-alpha receptor-associated death domain results from ubiquitin-dependent degradation in obstructive renal injury in rats2009
- Author(s)
  Misaki T, Yamamoto T, Suzuki S, Fukasawa H, Togawa A, Ohashi N, Suzuki H, Fujigaki Y, Oda T, Uchida C, Kitagawa K, Hattori T, Kitagawa M, Hishida A
- Journal Title
  
  Am.J.Pathol. 175
  
  Pages: 74-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590967
[Journal Article] A distinct population of tubular cells in the distal S3 segment contributes to S3 segment regeneration in rats following acute renal failure induced by uranyl acetate2008
- Author(s)
  Sakakima M, Fujigaki Y, Yamamoto T, Hishida A
- Journal Title
  
  Nephron Exp Nephrol 109
  
  Pages: 57-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590945
[Journal Article] 臨床腎臓学2008
- Author(s)
  菱田明, 藤垣嘉秀, 安田日出夫, 加藤明彦
- Journal Title
  
  日本腎臓学会誌 50
  
  Pages: 11-15
- Data Source
  KAKENHI-PROJECT-19790579
[Journal Article] The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcysteine in rats2008
- Author(s)
  Luo J, Tsuji T, Yasuda H, Sun Y, Fujigaki Y, Hishida A
- Journal Title
  
  Nephrol Dial Transplant 23
  
  Pages: 2198-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590945
[Journal Article] Intrarenal RAS activity and urinary angiotensinogen excretion in anti-thymocyte serum nephritis rats2008
- Author(s)
  Ohashi N, Yamamoto T, Huang Y, Misaki T, Fukasawa F, Suzuki H, Togawa A, Suzuki S, Fujigaki Y, Nakagawa T, Nakamura Y, Suzuki F, Kitagawa M, Hishida A
- Journal Title
  
  Am.J.Physiol.Renal Physiol. 295(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590967
[Journal Article] Immunohistochemica study on caveolin -lalpha in regenerating process tubular cells in gentamicin-induced acute tubular injury in rats2007
- Author(s)
  Fujigaki Y, Sakakima M, Sun Y, Goto T, Fukasawa H, Tsuji T, Yamamoto T, Hishida A
- Journal Title
  
  Virchows Arch 450
  
  Pages: 671-681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590945
[Journal Article] Association of prohepcidin and hepcidin-25 with erythropoietin response and ferritin in hemodialysis patients2007
- Author(s)
  Kato A, Tsuji T, Luo J, Sakao Y, Yasuda H, Hishida A.
- Journal Title
  
  Am J Nephrol 28
  
  Pages: 115-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790579
[Journal Article] Plasma protein extravasation and vascular endothelial growth factor expression with endothelial nitric oxide synthase induction in gentamicin-induced acute renal failure in rats.2004
- Author(s)
  Tetsuo Goto, Yoshihide ujigaki, Di Fei Sun, Tatsuo Yamamoto, Akira Hishida
- Journal Title
  
  Virchows Arch 444(4)
  
  Pages: 362-374
- Data Source
  KAKENHI-PROJECT-15590846
[Journal Article] Insulin-like growth factor-I increases p21 expression and attenuates cisplatin-induced acute renal injury in rats.2004
- Author(s)
  Hideo Yasuda, Akihiko Kato, Takehiko Miyaji, Hua Zhou, Akashi Togawa, Akira Hishida
- Journal Title
  
  Clin Exp Nephrol 8(1)
  
  Pages: 27-35
- NAID
  10012683920
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590846
[Journal Article] The induction of cell cycle regulatory and DNA repair proteins in cisplatin-induced acute renal failure.2004
- Author(s)
  Hua Zhou, Akihiko Kato, Hideo Yasuda, Takehiko Miyaji, Yoshihide Fujigaki, Tatsuo Yamamoto, Katsuhiko Yonemura, Akira Hishida
- Journal Title
  
  Pharmacology 200
  
  Pages: 111-120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590846
[Journal Article] Plasma protein extravasation and vascular endothelial growth factor expression with endothelial nitric oxide synthase induction in gentamicin-induced acute renal failure in rats.2004
- Author(s)
  Tetsuo Goto, Yoshihide Fujigaki, Di Fei Sun, Tatsuo Yamamoto, Akira Hishida
- Journal Title
  
  Virchows Arch 444(4)
  
  Pages: 362-374
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590846
[Journal Article] The induction of cell cycle regulatory and DNA repair proteins in cisplatin-induced acute renal failure.2004
- Author(s)
  Hua-Zhou, Akihiko, _Kato, Hideo Yasuda, Takehiko Miyaji, Yoshihide Fujigaki, Tatsuo Yamamoto, Katsuhiko Yonemura, Akira Hishida
- Journal Title
  
  Toxicology and Applied Pharmacology 200
  
  Pages: 111-120
- Data Source
  KAKENHI-PROJECT-15590846
[Journal Article] Insulin-like growth factor-I increases p21 expression and attenuates cisplatin-induced acute renal injury in rats.2004
- Author(s)
  Hideo Yasuda, Akihiko Kato, Takehiko Miyaji, Hua Zhou, Akashi Togawa, Akira Hishida
- Journal Title
  
  Clip Exp Nephrol 8(1)
  
  Pages: 27-35
- NAID
  10012683920
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590846
[Journal Article] The induction of cell cycle regulatory, and DNA repair proteins in cisplatin-induced acute renal failure.2004
- Author(s)
  Hua-Zhou, Akihiko Kato, Hideo Yasuda, Takehiko Miyaji, Yoshihide Fujigaki, Tatsuo Yamamoto, Katsuhiko Yonemura, Akira Hishida
- Journal Title
  
  Toxicology and Applied Pharmacology 200
  
  Pages: 111-120
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590846
[Presentation] シスプラチン(CDDP)誘発急性腎不全に対するN-アセチルシステイン(NAC)の効果の検討2009
- Author(s)
  安田日出夫、羅景慧、辻孝之、孫媛、榊間昌哲、戸川証、鈴木洋行、加藤明彦、菱田明
- Organizer
  第51回日本腎臓学会
- Data Source
  KAKENHI-PROJECT-19790579
[Presentation] 酢酸ウラニウム誘発ラット急性尿細管障害における細胞生存とHSP27/FAK発現2008
- Author(s)
  藤垣嘉秀(代表)、孫媛、榊間昌哲、辻孝之、戸川証、安田日出夫、鈴木洋行、菱田明
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡市
- Year and Date
  2008-06-01
- Data Source
  KAKENHI-PROJECT-19590945
[Presentation] The Prevalence and Outcome of Acute Kidney Injury Requiring Renal Replacement Therapy-A Japanese Population-Based Multicenter Prospective Survey2007
- Author(s)
  Yasuda H, Kato A, Fujigaki Y, Hishida A
- Organizer
  American society of nephrology renal week 2007 1-4 November
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-19590945
[Presentation] The prevalence and outcome of acute kidney injury requiring renal replacement therapy-a Japanese population-based multicenter prospective survey2007
- Author(s)
  Yasuda H, Kato A, Fujigaki Y, Hishida A.
- Organizer
  American Society of Nephrology
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-19790579
[Presentation] 正常および障害後の近位尿細管細胞再生現象. ワークショップ3腎の発生と再生-その分子機構と臨床応用に向けて-2007
- Author(s)
  藤垣嘉秀、榊間昌哲、菱田明
- Organizer
  第50回日本腎臓学会学術総会
- Place of Presentation
  浜松市
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19590945
[Presentation] 慢性腎臓病対策からみた薬剤性腎障害対策の課題. シンポジウム1薬剤性腎障害の発症機序と防御2007
- Author(s)
  菱田明, 藤垣嘉秀
- Organizer
  第34回日本トキシコロジー学会学術年会
- Place of Presentation
  東京
- Year and Date
  2007-06-27
- Data Source
  KAKENHI-PROJECT-19590945
[Presentation] Cell division and phenotype regression of proximal tubular cells in response to uranyl acetate insult in rats2007
- Author(s)
  Fujigaki Y, Sakakima M, Sun Y, Sakao Y, Tsuji T, Yamamoto T, Hishida A
- Organizer
  44th Congress of European Dialysis and Transplant Association. 21-24 June
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-19590945

1. FUJIGAKI Yoshihide (20283351)

# of Collaborated Projects: 7 results

# of Collaborated Products: 16 results
2. KATO Akihiko (60324357)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. YAMAMOTO Tatsuo (30200819)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
4. YASUDA Hideo (60432209)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. YONEMURA Katsuhiko (40252176)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 池谷直樹 (80283357)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SAKAKIMA Masanori (60402351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. SUN Yuen (90402346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. FUJIKURA Tomoyuki (00444349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. TSUJI Takayuki (30464126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. SAKAO Yukitoshi (60402335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. SUZUKI Hiroyuki (10452179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. ISHIDA Junko (50410501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. ODAMAKI Mari (00347387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HUANG Yanjie (30535563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. ISAKI Taro (20464125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. OGAWA Akashi (90467225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. HONDA Nishio (00010231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KOBAYASHI Shuzo (60195782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 熊谷裕通 (40183313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 大石和久 (90211094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YAMASHITA Fuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ARAI Takami

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HISHIDA Akira 菱田 名

Research Projects

Research Products

Co-Researchers

Effect of salt load on the intrarenal angiotensin activity and receptor-mediated prorenin system in kidney fibrosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of progenitor-like cells and infiltrative macrophages on renal tubular regeneration and their application on cell therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dual effects of NFκB inhibitors on viability of cancer and kidney induced by cisplatin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The prevention of acute renal failure through the intervention in the DNA repair system.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of p21, a cell cycle regulation factor, in the development of cisplatin-induced acute renal failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of interstitial cells on the recovery process from acute renal failure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of apoptosis in cisplatin-induced acute renal failure.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study on the factors which enhance the recovery from acute renal failure.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The roles of endothelin and growth factors in ischemic acute renal failure.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathogenesis of nonoliguric acute renal failure.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of anionic charge of the glomerular basement membrane.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Reduction of transforming growth factor-β type II receptor is caused by the enhanced ubiquitin-dependent degradation in human renal cell carcinoma2010

Author(s)

Journal Title

Data Source

[Journal Article] Cell division and phenotype regression of proximal tubular cells in response to uranyl acetate insult in rats2009

Author(s)

Journal Title

Data Source

[Journal Article] The dimethylthiourea-induced attenuation of cisplatin nephrotoxicity is associated with the augmented induction of heat shock proteins2009

Author(s)

HISHIDA Akira 菱田名