SHIMIZU Keiji 清水恵司

Researcher Number	70116044
Other IDs
Affiliation (based on the past Project Information) *help	2014: 高知大学, 教育研究部医療学系, 教授 2013 – 2014: 高知大学, 医歯学系, 教授 2012: 高知大学, 教育研究部医療学系, 教授 2011: 高知大学, 医療学系, 教授 2010 – 2011: 高知大学, 教育研究部・医療学系, 教授 2008: 高知大学, 教育研究部・医療学系, 教授 2008: 高知大学, 教育研究部医療学系, 教授
Review Section/Research Field	Principal Investigator Cerebral neurosurgery Except Principal Investigator Cerebral neurosurgery
Keywords	Principal Investigator 脳腫瘍 / エピジェネティクス / 分化 / 悪性脳腫瘍 / 幹細胞 / 非対称分裂 Except Principal Investigator 浸潤 / 悪性グリオーマ / アストロサイト / エピジェネティクス … More / グリオーマ / 血管新生 / 幹細胞 / TRAIL / IL12 / scFv / 癌 / 発現制御 / 遺伝学 / 発生・分化 / 免疫学 / 癌幹細胞 / 癌精巣抗原遺伝子 / 細胞分化 / 遺伝子治療 / 脳腫瘍 / ゲノムリプログラミング / 悪性脳腫瘍 / 分子生物学 / 変異 / がん幹細胞 / MUC18 / CD133 / 頭部外傷 / うつ病 / 脳内亜鉛 / グリア細胞 / 脳保護薬 / 活性酸素 / 5-lipoxygenase Less

Determination of stress sensitivity molecules that exacerbate depression after head injury
- Principal Investigator
  
  HIGASHI Youichirou
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kochi University
グリオーマ腫瘍幹細胞の浸潤能に関与するMUC18遺伝子を標的とした新規治療の開発
- Principal Investigator
  
  田村雅一
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kochi University
Effect of abnormalities in asymmetric cell divisions of neural stem cells on brain tumor initiationPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Keiji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kochi University
Functional analysis of genomic abnormalities in brain tumors by epigenetic reprogramming
- Principal Investigator
  
  YAWATA Toshio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kochi University
Preliminary study of the induction of malignant glioma apoptosis using mesenchymal stem cell-mediated delivery of TRAIL and IL12
- Principal Investigator
  
  NAKABAYASHI Hiromichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kochi University
Contribution of cancer stem cells to tumor heterogeneity; A search for cancer stem cell-specific immunogen
- Principal Investigator
  
  YAWATA Toshio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kochi University

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

[Book] 腫瘍内在幹細胞(寺本明(編)NS NOW No.5)(グリオーマ-その最新知見)2009
- Author(s)
  八幡俊男, 清水惠司
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-19591685
[Book] Neuroimmunology Research Focus, Nova Science Publishers, Inc.(Broglio PV (ed))2007
- Author(s)
  Kaji T, Tsuchiya T, Yawata T, Nakabayashi H, Yamada SM, Park KC, Shimizu K
- Publisher
  PU.1 is required for the activation of mouse embryonic stem cell-derived microglia
- Data Source
  KAKENHI-PROJECT-19591685
[Journal Article] Possible inhibitory role of endogenous 2-arachidonoylglycerol as an endocannabinoid in (±)-epibatidine-induced activation of central adrenomedullary outflow in the rat.2015
- Author(s)
  Shimizu T, Tanaka K, Shimizu S, Higashi Y, Yawata T, Nakamura K, Taniuchi K, Ueba T, Yuri K, Saito M.
- Journal Title
  
  Neuropharmacology.
  
  Volume: 95 Pages: 278-289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592133
[Journal Article] Elevated Cell Invasion in a Tumor Sphere Culture of RSV-M Mouse Glioma Cells2015
- Author(s)
  Nonaka M, Yawata T, Takemura M, Higashi Y, Nakai E, Shimizu K, Ueba T.
- Journal Title
  
  Neurologia medico-chirurgica
  
  Volume: 55 Issue: 1 Pages: 60-70
- DOI
  10.2176/nmc.oa.2014-0067
- NAID
  130004922269
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592133, KAKENHI-PROJECT-26462184
[Journal Article] Angiotensin II acting on brain AT1 receptors induces adrenaline secretion and pressor responses in the rat2014
- Author(s)
  Nakamura K, Shimizu T, Yanagita T, Nemoto T, Taniuchi K, Shimizu S, Dimitriadis F, Yawata T, Higashi Y, Ueba T, Saito, M
- Journal Title
  
  Sci. Rep.
  
  Volume: 4 Pages: 7248-7248
- DOI
  10.1038/srep07248
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591013, KAKENHI-PROJECT-24592133, KAKENHI-PROJECT-26460909, KAKENHI-PROJECT-26462184, KAKENHI-PROJECT-26861271
[Journal Article] Central bom besin possibly induces S-nitrosylation of cyclooxygenase-1 in pre-sympathetic neurons of rat hypothalamic paraventric ular nucleus2014
- Author(s)
  Tanaka K, Shimizu T, Higashi Y, Nakamura K, Taniuchi K, Dimitriadis F, Shimizu S, Yokotani K, Saito M.
- Journal Title
  
  Life Sciences
  
  Volume: 100 Pages: 85-96
- DOI
  10.1016/j.lfs.2014.01.079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790744, KAKENHI-PROJECT-24591013, KAKENHI-PROJECT-24592133, KAKENHI-PROJECT-25461023, KAKENHI-PROJECT-25670354, KAKENHI-PROJECT-26861271
[Journal Article] Possible involvement of brain pro staglandin E_2 and prostanoid EP_3 recepto rs in prostaglandin E_2 glycerol ester-in duced activation of central sympathetic outflow in the rat2014
- Author(s)
  Shimizu T, Tanaka K, Nakamura K, Taniuchi K, Yawata T, Higashi Y, Ueba T, Dimitriadis F, Shimizu S, Yokotani K, Saito M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 82 Pages: 19-27
- DOI
  10.1016/j.neuropharm.2014.03.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23790744, KAKENHI-PROJECT-24591013, KAKENHI-PROJECT-24592133, KAKENHI-PROJECT-25461023, KAKENHI-PROJECT-25462267, KAKENHI-PROJECT-25670354, KAKENHI-PROJECT-26462184, KAKENHI-PROJECT-26861271
[Journal Article] Suppression of oxidative stress and 5-lipoxygenase activation by edaravone improves depressive-like behavior after concussion2014
- Author(s)
  Higashi Y., Hoshijima M., Yawata T., Nobumoto A., Tsuda M., Shimizu T., Saito M., Ueba T.
- Journal Title
  
  J Neurotrauma
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592133
[Journal Article] Regulatory effects of Spirulina complex polysaccharides on growth of murine RSV-M gliomas cells through toll-like receptor 42013
- Author(s)
  Kawanishi Y, Tominaga A, Okuyama H, Fukuoka S, Taguchi T, Kusumoto Y, Yawata T, Fujimoto Y, Ono S, Shimizu K
- Journal Title
  
  Microbiol Immunol
  
  Volume: 57 Pages: 63-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659690
[Journal Article] Attenuation of axonal injury and oxidative stress by edaravone protects against cognitive impairments after traumatic brain injury2013
- Author(s)
  Ohta M, Higashi Y, Yawata T, Kitahara M, Nobumoto A, Ishida R, Tsuda M, Fujimoto Y, Shimizu K
- Journal Title
  
  Brain Res
  
  Volume: 1490 Pages: 184-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659690
[Journal Article] Attenuation of axonal injury and oxidative stress by edaravone protects against cognitive impairments after traumatic brain injury.2013
- Author(s)
  Ohta M, Higashi Y, Yawata T, Kitahara M, Nobumoto A, Ishida R, Tsuda M, Fujimoto Y, Shimizu K
- Journal Title
  
  Brain Res
  
  Volume: 1490 Pages: 184-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591614
[Journal Article] Regulatory effects of Spirulina complex polysaccharides on growth of murine RSV-M gliomas cells through toll-like receptor 4.2013
- Author(s)
  Kawanishi Y, Tominaga A, Okuyama H, Fukuoka S, Taguchi T, Kusumoto Y, Yawata T, Fujimoto Y, Ono S, Shimizu K
- Journal Title
  
  Microbiol Immunol
  
  Volume: 57 Pages: 63-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591614
[Journal Article] Attenuation of axonal injury and oxidative stress by edaravone protects against cognitive impairments after traumatic brain injury2013
- Author(s)
  Ohta M
- Journal Title
  
  Brain Research
  
  Volume: 1490 Pages: 184-192
- DOI
  10.1016/j.brainres.2012.09.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591614, KAKENHI-PROJECT-23659690, KAKENHI-PROJECT-24592133
[Journal Article] Stereoscopic virtual realistic surgical simulation in intracranial aneurysms2012
- Author(s)
  Nakabayashi H, Shimizu K
- Journal Title
  
  Neurology India
  
  Volume: 60 Pages: 191-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659690
[Journal Article] Identification and functional characterization of glioma-specific promoters and their application in suicide gene therapy.2011
- Author(s)
  Yawata T, Maeda Y, Okiku M, Ishida E, Ikenaka K, Shimizu K
- Journal Title
  
  J Neurooncol
  
  Volume: 104 Pages: 497-507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591614
[Journal Article] Identification and functional characterization of glioma-specific promoters and their application in suicide gene therapy2011
- Author(s)
  Yawata T, Maeda Y, Okiku M, Ishida E, Ikenaka K, Shimizu K
- Journal Title
  
  J Neurooncol
  
  Volume: 04 Pages: 497-507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659690
[Journal Article] Enhanced expression of cancer testis antigen genes in glioma stem cells.2010
- Author(s)
  Yawata T, Nakai E, Park KC, Chihara T, Kumasawa A, Toyonaga S, Masahira N, Nakabayashi H, Kaji T, Shimizu K
- Journal Title
  
  Molecular Carcinogenesis
  
  Volume: 49 Pages: 532-544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591614
[Journal Article] Anti-invasive and antiangiogenic effects of MMI-166 on malignant glioma cells.2010
- Author(s)
  Nakabayashi H, Yawata T, Shimizu K
- Journal Title
  
  BMC Cancer
  
  Volume: 10 Pages: 339-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591614
[Journal Article] Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma2008
- Author(s)
  Nakai E, Oark K, Yawata T, Chihara T, Kumazawa A, Nakabayashi H, Shimizu K
- Journal Title
  
  Cancer Investigation (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591684
[Journal Article] Clinico-pathological significance of RCAS1 expression in gliomas : A potential mechanism of tumor immune escape2007
- Author(s)
  Nakabayashi H, Nakashima M, Hara M, Toyonaga S, Yamada SM, Park KC, Shimizu K
- Journal Title
  
  Cancer Letters 246
  
  Pages: 182-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591684
[Journal Article] Gene therapy strategies for treating brain tumors: Retroviruses are still good candidates for therapeutic vectors
- Author(s)
  Yawata T, Shimizu K
- Journal Title
  
  Open J Genet.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659690
[Journal Article] Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma
- Author(s)
  Nakai E, Park K, Yawata T, Chihara T, Kumazawa A, Nakabayashi H, Shimizu K
- Journal Title
  
  Cancer Investigation (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591685
[Journal Article] Gene therapy strategies for treating brain tumors: Retroviruses are still good candidates for therapeutic vectors.
- Author(s)
  Yawata T, Shimizu K
- Journal Title
  
  Open J Genet
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591614
[Patent] 腫瘍特異的プロモーターおよびその用途2009
- Inventor(s)
  清水惠司、八幡俊男
- Industrial Property Rights Holder
  国立大学高知大学
- Industrial Property Number
  2009-095888
- Filing Date
  2009-04-10
- Overseas
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] Development of a high-titer retrovirus production system for glioma gene therapy.2013
- Author(s)
  Shimizu K
- Organizer
  Joint Neurosurgical Convention 2013
- Place of Presentation
  Hilton Waikoloa Village (U.S.A.)
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] Development of a high-titer retrovirus production system for glioma gene therapy2013
- Author(s)
  Shimizu K
- Organizer
  Joint Neurosurgical Convention 2013
- Place of Presentation
  Waikoloa, Hawaii, U.S.A
- Data Source
  KAKENHI-PROJECT-23659690
[Presentation] Development of a high-titer retrovirus production system for glioma gene therapy.2013
- Author(s)
  Shimizu K
- Organizer
  Joint Neurosurgical Convention 2013
- Place of Presentation
  Hilton Waikoloa Village (U.S.A.)
- Data Source
  KAKENHI-PROJECT-23659690
[Presentation] Development of a high-titer retrovirus production system for glioma gene therapy.2013
- Author(s)
  Shimizu K
- Organizer
  Joint Neurosurgical Convention 2013
- Place of Presentation
  Waikoloa, Hawaii, U.S.A.
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] Multidrug-resistance (MDR-1) gene expression in immature glioma cells2012
- Author(s)
  Shimizu K
- Organizer
  American Association for Cancer Research, Annual Meeting 2012
- Place of Presentation
  Chicago, IL, U.S.A.
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] 悪性グリオーマの治療に対する新たな展開2012
- Author(s)
  清水　惠司
- Organizer
  第5回静岡県脳腫瘍研究会
- Place of Presentation
  アクトシティー浜松（静岡）
- Invited
- Data Source
  KAKENHI-PROJECT-23659690
[Presentation] Towards a clinical trial of gene therapy for malignant glioma using highly concentrated retrovirus solution.2012
- Author(s)
  Shimizu K
- Organizer
  ESGCT 20th Anniversary Congress in Collaboration with the SFTCG
- Place of Presentation
  Palais des Congres (France)
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] 悪性グリオーマに対する新たな治療法を求めて2012
- Author(s)
  清水　惠司
- Organizer
  第69回山形脳神経外科懇話会
- Place of Presentation
  山形国際ホテル（山形）
- Invited
- Data Source
  KAKENHI-PROJECT-23659690
[Presentation] Multidrug-resistance (MDR-1) gene expression in immature glioma cells2012
- Author(s)
  Shimizu K
- Organizer
  American Association for Cancer Research, Annual Meeting 2012
- Place of Presentation
  Chicago, IL, U.S.A
- Data Source
  KAKENHI-PROJECT-23659690
[Presentation] 頭部外傷による軸索損傷と認知機能障害に対するエダラボンの効果の解析2012
- Author(s)
  大田学、東洋一郎、北原正大、八幡俊男、星島陸宏、藤本康倫、清水恵司
- Organizer
  第１３回日本分子脳神経外科学会
- Place of Presentation
  熊本（熊本市国際交流会館）
- Data Source
  KAKENHI-PROJECT-24592133
[Presentation] Towards a clinical trial of gene therapy for malignant glioma using highly concentrated retrovirus solution.2012
- Author(s)
  Shimizu K
- Organizer
  ESGCT 20th Anniversary Congress in Collaboration with the SFTCG
- Place of Presentation
  Palais des Congres (France)
- Data Source
  KAKENHI-PROJECT-23659690
[Presentation] Multidrug-resistance (MDR-1) gene expression in immature glioma cells.2012
- Author(s)
  Shimizu K
- Organizer
  American Association for Cancer Research, Annual Meeting 2012
- Place of Presentation
  McCormick Place (U.S.A.)
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] Edaravone supresses axonal injury and improves memory dysfunction after traumatic brain injury in mice2012
- Author(s)
  Higashi Y, Ohta M, YawataT, Kitahara M, Fujimoto Y, Shimizu K
- Organizer
  35回日本神経科学大会
- Place of Presentation
  名古屋（名古屋国際会議場）
- Data Source
  KAKENHI-PROJECT-24592133
[Presentation] Towards a clinical trial of gene therapy for malignant glioma using highly concentrated retrovirus solution2012
- Author(s)
  Shimizu K
- Organizer
  ESGCT 20th Anniversary Congress in Collaboration with the SFTCG
- Place of Presentation
  Versailles, France
- Data Source
  KAKENHI-PROJECT-23659690
[Presentation] Towards a clinical trial of gene therapy for malignant glioma using highly concentrated retrovirus solution.2012
- Author(s)
  Shimizu K
- Organizer
  ESGCT 20th Anniversary Congress in Collaboration with the SFTCG
- Place of Presentation
  Versailles, France
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] Multidrug-resistance (MDR-1) gene expression in immature glioma cells.2012
- Author(s)
  Shimizu K
- Organizer
  American Association for Cancer Research, Annual Meeting 2012
- Place of Presentation
  McCormick Place (U.S.A.)
- Data Source
  KAKENHI-PROJECT-23659690
[Presentation] Up-regulation and invasive role of MUC18/MCAM in glioma sphere culture2011
- Author(s)
  Shimizu K
- Organizer
  AACR 102nd Annual Meeting
- Place of Presentation
  Orange County Convention Center (Orlando, FL, U.S.A.)
- Year and Date
  2011-04-05
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] Up-regulation and invasive role of MUC18/MCAM in glioma sphere culture. American Association for Cancer Research2011
- Author(s)
  Shimizu K
- Organizer
  102nd Annual Meeting
- Place of Presentation
  Orlando, Florida, U.S.A.
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] Brain tumor selective gene expression and therapy mediated by recombinant retroviruses containing the SSX4 promoter2011
- Author(s)
  Shimizu K
- Organizer
  ESGCT and BSGT Collaborative Congress 2011
- Place of Presentation
  Brighton, U.K.
- Data Source
  KAKENHI-PROJECT-23659690
[Presentation] Brain tumor selective gene expression and therapy mediated by recombinant retroviruses containing the SSX4 promoter2011
- Author(s)
  Shimizu K
- Organizer
  ESGCT and BSGT Collaborative Congress 2011
- Place of Presentation
  Brighton Centre (Brighton, U.K.)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] Brain tumor selective gene expression and therapy mediated by recombinant retroviruses containing the SSX4 promoter.2011
- Author(s)
  Shimizu K
- Organizer
  ESGCT and BSGT Collaborative Congress 2011
- Place of Presentation
  The Brighton Centre（U.K.）
- Data Source
  KAKENHI-PROJECT-23659690
[Presentation] Brain tumor selective gene expression and therapy mediated by recombinant retroviruses containing the SSX4 promoter.2011
- Author(s)
  Shimizu K
- Organizer
  ESGCT and BSGT Collaborative Congress 2011
- Place of Presentation
  Brighton, U.K.
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] Development of brain tumor-specific targeted system by using retroviral-mediated gene therapy with SSX4 promotor.2010
- Author(s)
  Shimizu K
- Organizer
  AACR 101st Annual Meeting 2010
- Place of Presentation
  Washington convention center (Washington, DC, U.S.A.)
- Year and Date
  2010-04-18
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] Development of a suicide gene therapy for the treatment of glioblastoma using tumor-specific retrovirus vectors.2010
- Author(s)
  Shimizu K
- Organizer
  18th Annual Congress of the European Society of Gene & Cell Therapy
- Place of Presentation
  Stella Polare Convention Centre (Milano, Italy)
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] Development of a suicide gene therapy for the treatment ofglioblastoma using tumor-specific retrovirus vectors.2010
- Author(s)
  Shimizu K
- Organizer
  18th Annual Congress of the European Society of Gene & Cell Therapy
- Place of Presentation
  Milano, Italy.
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] Development of brain tumor-specific targeted system by using retroviral-mediated gene therapy with SSX4 promoter.2010
- Author(s)
  Shimizu K
- Organizer
  American Association for Cancer Research, 101st Annual Meeting 2010
- Place of Presentation
  Washington, DC, U.S.A.
- Data Source
  KAKENHI-PROJECT-22591614
[Presentation] ES細胞由来神経細胞移植によるパーキンソン病モデルの機能回復と脳内免疫応答の解析.2009
- Author(s)
  清水惠司, 他
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京都東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] 脳腫瘍臨床組織に由来する癌幹細胞の樹立と性状の検討2009
- Author(s)
  八幡俊男, 中居永一, 熊澤綾乃, 石田恵理, 田村雅一, 清水惠司
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] ES細胞由来神経細胞移植によるパーキンソン病モデルの機能回復と脳内免疫応答の解析2009
- Author(s)
  清水惠司, 八幡俊男, 熊澤綾乃, 中居永一, 野中大伸, 田村雅一
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] 同系及び異系パーキンソン病モデルに対し, 免疫抑制剤非投与時におけるES細胞由来のTH細胞移植による機能回復の検討.2008
- Author(s)
  清水恵司, 他
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京都東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] パーキンソン病モデルマウスに移植された異系ES細胞由来ドーパミン作動性神経細胞の長期生存2008
- Author(s)
  梶豪雄, 中居永一, 土屋孝弘, 熊澤綾乃, 八幡俊男, 政平訓貴, 清水惠司
- Organizer
  第7回日本再生医療学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] 同系及び異系パーキンソン病モデルに対し,免疫抑制剤非投与時におけるES細胞由来のTH細胞移植による機能回復の検討2008
- Author(s)
  清水惠司, 熊澤綾乃, 八幡俊男, 中居永一
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] グリオーマに対するSpirulina複合多糖体の抗腫瘍効果2008
- Author(s)
  川西裕, 富永明, 奥山洋美, 田口尚弘, 楠本豊, 八幡俊男, 小野史郎, 清水惠司
- Organizer
  社団法人日本脳神経外科学会第67回学術総会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] Evaluation of CD133 expression in brain tumors using tissue array2008
- Author(s)
  Shimizu K, Kumazawa A, Toyonaga S, Masahira N, Nakabayashi H, Park K, Yawata T
- Organizer
  AACR Annual Meeting 2008
- Place of Presentation
  San Diego, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] 脳腫瘍組織における体性幹細胞マーカーCD133の発現頻度2008
- Author(s)
  八幡俊男, 熊澤綾乃, 川西裕, 田村雅一, 清水惠司
- Organizer
  第26回日本脳腫瘍学会
- Place of Presentation
  愛媛
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] Spirulina 複合多糖体のTLR4依存的抗腫瘍効果の検討2008
- Author(s)
  川西裕, 富永明, 奥山洋美, 田口尚弘, 楠本豊, 八幡俊男, 小野史郎, 清水惠司
- Organizer
  第21回日本バイオセラピィ学会学術集会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] 同系および異系マウスパーキンソンモデルに移植したES細胞由来TH産生細胞のMHC抗原の表現性2008
- Author(s)
  清水惠司, 熊澤綾乃, 中居永一, 田村雅一, 八幡俊男
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] マウスES細胞由来ドーパミン産生神経の移植によるマウスパーキンソン病モデルの機能回復と脳内免疫応答の解析2008
- Author(s)
  熊澤綾乃, 八幡俊男, 梶豪雄, 布施理子, 清水惠司
- Organizer
  神経組織の成長・再生・移植研究会第23回学術集会
- Place of Presentation
  千葉
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] マウスグリオーマ幹細胞の浸潤能,および免疫組織学的解析2008
- Author(s)
  中居永一, 中林博道, 小宮山雅樹, 政平訓貴, 川西裕, 清水惠司
- Organizer
  社団法人日本脳神経外科学会第67回学術総会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] Killing activity of suicide gene therapy against cancer stem cells2008
- Author(s)
  Shimizu K, Ikenaka K, Kawanishi Y, Tamura M, Yawata T
- Organizer
  16th European Society of Gene & Cell Theraphy Annual Congress
- Place of Presentation
  Brugge, Belgium
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] ヒト・グリオーマ細胞に対するparthenolideの抗腫瘍効果について2008
- Author(s)
  中林博道, 八幡俊男, 田村雅一, 清水惠司
- Organizer
  社団法人日本脳神経外科学会第67回学術総会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] 同系および異系マウスパーキンソンモデルに移植したES細胞由来TH産生細胞のMHC抗原の表現性.2008
- Author(s)
  清水惠司, 他
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都府国立京都国際会館
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] Evaluation of CD133 expression in brain tumors using tissue array.2008
- Author(s)
  Shimizu K, et al.
- Organizer
  AACR Annual Meeting 2008
- Place of Presentation
  San Diego Convention Center, San Diego, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] Killing activity of suicide gene therapy against cancer stem cells.2008
- Author(s)
  Shimizu K, el al.
- Organizer
  16th European Society of Gene & Cell Theraphy Annual Congress
- Place of Presentation
  Concertgebouw, Brugge, Belgium
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] Enhanced expression of cancer testis antigen genes in cancer stem cells derived from glioma cell lines2008
- Author(s)
  Yawata T, Chihara T, Kumazawa A, Nakai E, Park K, Shimizu K
- Organizer
  An AACR Special Conference in Cancer Research ; The Role of Cancer Stem Cells in the Initiation and Propagation of Tumorigenesis
- Place of Presentation
  Los Angeles, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] Killing activity of suicide gene therapy against cancer stem cells.2008
- Author(s)
  Shimizu K, et al.
- Organizer
  16th European Society of Gene & Cell Theraphy Annual Congress
- Place of Presentation
  Concertgebouw, Brugge, Belgium
- Data Source
  KAKENHI-PROJECT-19591684
[Presentation] Toll-like receptor 4を介したスピルリナ複合多糖体の抗腫瘍効果2008
- Author(s)
  川西裕, 富永明, 奥山洋美, 田口尚弘, 楠本豊, 八幡俊男, 小野史郎, 清水惠司
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] Killing activity of suicide gene therapy against cancer stem cells2008
- Author(s)
  Shimizu K, Ikenaka K, Kawanishi Y, Tamura M, Yawata T
- Organizer
  16th European Society of Gene & Cell Theraphy Annual Congress
- Place of Presentation
  Belgium
- Data Source
  KAKENHI-PROJECT-19591684
[Presentation] ヒト・グリオーマ細胞に対するparthenolide の抗腫瘍効果について2008
- Author(s)
  中林博道, 八幡俊男, 田村雅一, 清水惠司
- Organizer
  社団法人日本脳神経外科学会第67回学術総会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-19591684
[Presentation] Enhanced expression of cancer testis antigen genes in cancer stem cells derived from glioma cell lines2007
- Author(s)
  Yawata T, Nakai E, Park KC, Shimizu K
- Organizer
  第66回日本癌学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] グリオーマ癌幹細胞における癌精巣抗原遺伝子の発現増強2007
- Author(s)
  八幡俊男, 中居永一, 千原隆弘, 熊澤綾乃, 豊永晋一, 朴啓彰, 清水惠司
- Organizer
  第8回日本分子脳神経外科学会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] リオーマがん幹細胞におけるMDR1発現と薬剤耐性能2007
- Author(s)
  朴啓彰, 八幡俊男, 中居永一, 熊澤綾乃, 千原隆弘, 中林博道, 清水惠司
- Organizer
  第66回社団法人日本脳神経外科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] 悪性グリオーマにおける癌精巣抗原遺伝子の発現と腫瘍細胞分化レベルの相関2007
- Author(s)
  清水惠司, 八幡俊男, 中居永一, 熊澤綾乃, 千原隆弘, 政平訓貴, 朴啓彰
- Organizer
  第25回日本脳腫瘍学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] グリオーマ癌幹細胞における癌精巣抗原遺伝子の発現亢進2007
- Author(s)
  清水惠司, 八幡俊男, 中居永一, 千原隆弘, 熊澤綾乃, 朴啓彰
- Organizer
  第66回社団法人日本脳神経外科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] マウスグリオーマ腫瘍幹細胞 : 神経幹細胞との比較2007
- Author(s)
  豊永晋一, 中居永一, 八幡俊男, 梶豪雄, 川西裕, 井川直樹, 政平訓貴, 中林博道, 朴啓彰, 清水惠司
- Organizer
  第66回社団法人日本脳神経外科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] Killing activity of HSV-TK/GCV suicide gene therapy for cancer stem cells derived from malignant glioma2007
- Author(s)
  Shimizu K, Yawata T, Nakai E, Toyonaga S, Chihara T, Maeda Y, Okiku M, Masahira N, Ikenaka K
- Organizer
  5th Australasian Gene Therapy Society Meeting
- Place of Presentation
  Canberra, Australia
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] マウスグリオーマ腫瘍幹細胞の形態学的特徴 : 神経幹細胞との比較2007
- Author(s)
  豊永晋一, 中居永一, 八幡俊男, 梶豪雄, 政平訓貴, 井川直樹, 中林博道, 山田昌興, 朴啓彰, 清水惠司
- Organizer
  第25回日本脳腫瘍病理学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-19591685
[Presentation] マウスグリオーマ腫瘍幹細胞の遺伝子発現、および免疫組織学的解析2007
- Author(s)
  中居永一, 八幡俊男, 豊永晋一, 梶豪雄, 朴啓彰, 清水惠司
- Organizer
  第25回日本脳腫瘍病理学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-19591685

1. YAWATA Toshio (40380323)

# of Collaborated Projects: 6 results

# of Collaborated Products: 47 results
2. HIGASHI Yoichiro (80380062)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. MASAHIRA Noritaka (80444769)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. NAKABAYASHI Hiromichi (70346716)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
5. KAJI Takao (70343366)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. TAMURA Masakazu (40516150)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 清水惠司 (50162699)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. UEBA Tetsuya (00314203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. FUJIMOTO Yasunori (80589789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. SHIMIZU Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. TANAKA Kenjirou

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 谷内恵介

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. 中村久美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. 清水翔吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
15. 齋藤源顕

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
16. 小谷典弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

SHIMIZU Keiji 清水 恵司

Research Projects

Research Products

Co-Researchers

Determination of stress sensitivity molecules that exacerbate depression after head injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

グリオーマ腫瘍幹細胞の浸潤能に関与するMUC18遺伝子を標的とした新規治療の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of abnormalities in asymmetric cell divisions of neural stem cells on brain tumor initiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of genomic abnormalities in brain tumors by epigenetic reprogramming

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Preliminary study of the induction of malignant glioma apoptosis using mesenchymal stem cell-mediated delivery of TRAIL and IL12

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Contribution of cancer stem cells to tumor heterogeneity; A search for cancer stem cell-specific immunogen

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 腫瘍内在幹細胞(寺本明(編)NS NOW No.5)(グリオーマ-その最新知見)2009

Author(s)

Publisher

Data Source

[Book] Neuroimmunology Research Focus, Nova Science Publishers, Inc.(Broglio PV (ed))2007

Author(s)

Publisher

Data Source

[Journal Article] Possible inhibitory role of endogenous 2-arachidonoylglycerol as an endocannabinoid in (±)-epibatidine-induced activation of central adrenomedullary outflow in the rat.2015

Author(s)

Journal Title

Data Source

[Journal Article] Elevated Cell Invasion in a Tumor Sphere Culture of RSV-M Mouse Glioma Cells2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Angiotensin II acting on brain AT1 receptors induces adrenaline secretion and pressor responses in the rat2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Central bom besin possibly induces S-nitrosylation of cyclooxygenase-1 in pre-sympathetic neurons of rat hypothalamic paraventric ular nucleus2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Possible involvement of brain pro staglandin E_2 and prostanoid EP_3 recepto rs in prostaglandin E_2 glycerol ester-in duced activation of central sympathetic outflow in the rat2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppression of oxidative stress and 5-lipoxygenase activation by edaravone improves depressive-like behavior after concussion2014

Author(s)

Journal Title

Data Source

[Journal Article] Regulatory effects of Spirulina complex polysaccharides on growth of murine RSV-M gliomas cells through toll-like receptor 42013

SHIMIZU Keiji 清水恵司