AKISAKA Toshitaka 明坂年隆

… Alternative Names

明坂年隆アキサカトシタカ

TOSHITAKA Akisaka 明坂年隆

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Researcher Number	70116523
Other IDs
External Links
Affiliation (Current)	2022: 朝日大学, 歯学部, 教授
Affiliation (based on the past Project Information) *help	2009 – 2011: Asahi University, 歯学部, 教授 2004 – 2007: 朝日大学, 歯学部, 教授 1995 – 2002: 朝日大学, 歯学部, 教授 1993: 朝日大学, 歯学部, 教授 1990 – 1991: 朝日大学, 歯学部, 教授 1988: Asahi University, Professor, 歯学部, 教授 1987: 広島大学, 歯学部, 講師
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Morphological basic dentistry Except Principal Investigator Morphological basic dentistry
Keywords	Principal Investigator 破骨細胞 / 培養破骨細胞 / ポドゾーム / 細胞骨格 / podosome / 細胞剥離 / 急速凍結 / cultured osteoclast / cytoskeleton / clathrin sheet … More / cell shearing / 凍結乾燥レプリカ / 三次元可視化 / プロトンポンプ / immunostaining / quick-freezing / freeze-dried replica / クラスリンシート / 超微構造 / quick freezing / 接着構造 / 細胞膜面 / 細胞膜ドメイン / 石灰化基質 / 膜裏打ち構造 / アクチン極性 / アクチンベルト / アクチン線維 / 微小管 / 翻訳後修飾 / 刷子縁 / 明帯 / 膜内粒子 / フリーズレプリカ / 凍結置換 / 凍結レプリカ / マイクロウエ-ブ / 造骨細胞 / ギャップ結合 / Osteoclast / Ruffled border / Clear zone / Cytoskeleton / Membrane particle / Freeze-replica / Quick freezing / 酸性化領域 / DAMP染色 / pH / 共焦点レーザー顕微鏡 / 培養 / 酸性化 / DAMP / 蛍光顕微鏡 / acidic compartment / DAMP staining / pH probe / Laser scanning microscopy / レーザー顕微鏡 / 分離培養破骨細胞 / F-アクチン / G-アクチン / ゲルゾリン / ultrastructure / 表面レプリカ / 三次元観察 / アクチン細胞骨格 / 超音波細胞破砕 / ミオシンサブフラグメント / 超音波細胞剥離 / OSTEOCLAST / CELL SHEARING / SURFACE REPLICATION / CLATHRIN SHEET / CYTOSKELETON / PODOSOME / 3-D ARCHITECTURE / フォーカルアドヒジョン / アクチンリング / ステレオペア / 3-D可視化 / 細胞接着 / トモグラフィー / 細胞剥離法 / クラスリン / 急速凍結・乾燥レプリカ / 電子顕微鏡トモグラフィー / osteoclast / focal adhesion / actin ring / stereopair / 3-D visualization / 凍結技法 / クラスリン被覆 / シグナル伝達 / 電子顕微鏡 / アクチン関連蛋白 / コロイド金 / ステレオペア観察 / osteoclasts / clathrin … More Except Principal Investigator 急速凍結 / 石灰化 / 破骨細胞 / Osteoclast / 軟骨 / プロチオグリカン / 硫酸基 / 軟骨細胞 / グリコサミノグリカン / 高鉄ジアミン / 小柱エナメル質 / 無柱エナメル質 / エナメルタンパク / エナメル芽細胞 / 硫酸化複合糖質 / 急速凍結置換固定 / プロパン / ^<35>Sーオ-トラジオグラフィ- / エナメル質基質形成期 / Prism enamel / Prismless enamel / Enamel protein / Ameloblasts / Sulfated glycoconjugates / Calcification / 刷子縁 / 細胞骨格 / 超微細構造 / ディープエッチング / 急速冷凍凍結置換 / 凍結乾燥 / 細胞裏打ち構造 / 急速凍結凍結置換 / 細胞膜裏打ち構造 / ruffled border / cytoskeleton / ultrastructure / deep-etching / quick freezing / 凍結置換 / 凍結レプリカ / 酸性フォスファターゼ / 膜内粒子 / 前破骨細胞 / フリーズ・レプリカ法 / 酒石酸耐性酸性フォスファターゼ / Quick freezing / Freeze-substitution / Freeze-fracture Less

Ultra and molecular structures of the adhesive apparatus occurred in the osteoclastsPrincipal Investigator
- Principal Investigator
  
  AKISAKA Toshitaka
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
Adhesion structures and their cytoskeleton-membrane interactions at podosomes as a specific signal transduction site of osteoclastsPrincipal Investigator
- Principal Investigator
  
  AKISAKA Toshitaka
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
Podosome structures as a focal adhesion appeared in osteoclasts in culturePrincipal Investigator
- Principal Investigator
  
  AKISAKA Toshitaka
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
CLATHRIN SHEETS AND CYTOSKELETAL STRCTURES ON THE PROTOPLASMIC SURAFCE OF THE VENTRAL MEMBRANES OF OSTEOCLASTS IN CULTUREPrincipal Investigator
- Principal Investigator
  
  AKISAKA Toshitaka
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  ASAHI UNIVERSITY
The ultrastructure of osteoclast ruffled border and resorption lacuna
- Principal Investigator
  
  YOSHIDA Hisaho
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
Clathrin sheets and cytoskeletal podosomes on the cytoplasmic side of ventral membranes of cultured osteoclastsPrincipal Investigator
- Principal Investigator
  
  AKISAKA Toshitaka
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
Membrane associated clathrin sheets as a possible adhesion structure in cultured osteoclastsPrincipal Investigator
- Principal Investigator
  
  AKISAKA Toshitaka
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
Visualization of acidic pH compartments on cultured osteoclastsPrincipal Investigator
- Principal Investigator
  
  AKISAKA Toshitaka
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  ASAHI UNIVERSITY
急速凍結軟骨基質における硫酸基の超微局在と石灰化
- Principal Investigator
  
  KOGAYA Yasutoku
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
Role of sulfated glycoconjugates ectodermally derived hard tissue formation
- Principal Investigator
  
  YOSHIDA Hisaho, 小萱康徳
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
Ultrastructural investigation of the membrane modifications of osteoclastsPrincipal Investigator
- Principal Investigator
  
  AKISAKA Toshitaka
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Asahi University
Ultrastructure of bone resorption by osteoclastsPrincipal Investigator
- Principal Investigator
  
  MITSUTERU Hosoi, 明坂年隆
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  HIROSHIMA UNIVERSITY

All 2012 2011 2010 2009 2008 2006

All Journal Article Presentation

[Journal Article] 細胞剥離法で明らかになる培養破骨細胞の接着側細胞膜面の裏打ち構造2012
- Author(s)
  明坂年隆
- Journal Title
  
  顕微鏡
  
  Volume: 47 Pages: 38-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592350
[Journal Article] 細胞膜剥離法で明らかになる培養破骨細胞の接着側細胞膜面の裏打ち構造顕微鏡2012
- Author(s)
  明坂年隆
- Volume
  47巻
- Pages
  38-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592350
[Journal Article] 細胞膜剥離法で明らかになる培養破骨細胞の接着側細胞膜面の裏打ち構造2012
- Author(s)
  明坂年隆
- Journal Title
  
  顕微鏡
  
  Volume: 47 Pages: 38-43
- NAID
  10030552225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592350
[Journal Article] Differential distribution of posttranslationally modified microtubules in osteoclasts2011
- Author(s)
  Akisaka T, 他2名
- Journal Title
  
  J Histochemistry and Cytochemistry
  
  Volume: 59 Pages: 630-638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592350
[Journal Article] Differential distribution of posttranslationally modified microtubules in osteoclasts2011
- Author(s)
  Akisaka T, 他2名
- Journal Title
  
  J Histochem Cytochem
  
  Volume: Vol.59 Pages: 630-638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592350
[Journal Article] Differential distribution of posttranslationally modified microtubules inosteoclasts2011
- Author(s)
  Akisaka T, 他2名
- Journal Title
  
  J Histochemistry Cytochemistry
  
  Volume: Vol.S9 no.6 Pages: 630-638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592350
[Journal Article] 培養破骨細胞における接着側細胞膜面の三次元可視化2011
- Author(s)
  明坂年隆
- Journal Title
  
  The Bone
  
  Volume: 25巻 Pages: 183-187
- Data Source
  KAKENHI-PROJECT-21592350
[Journal Article] 培養破骨細胞における接着側細胞膜面の三次元可視化2011
- Author(s)
  明坂年隆
- Journal Title
  
  The Bone(和文季刊雑誌)
  
  Volume: 25
- Data Source
  KAKENHI-PROJECT-21592350
[Journal Article] Adhesion structures and their cytoskeleton-membrane interactions at podosomes of osteoclasts in sulture2008
- Author(s)
  Akisaka T, et. al.
- Journal Title
  
  Cell Tiss Res 331
  
  Pages: 625-641
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592020
[Journal Article] Adhesion structures and their cytoskeleton-membrane interactions at podosomes of osteoclasts in culture2008
- Author(s)
  Akisaka T, et. al.
- Journal Title
  
  Cell Tissue Research 331
  
  Pages: 625-641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592020
[Journal Article] Adhesion structures and their cytoskeleton-membrane2008
- Author(s)
  Akisaka T, et. al.
- Journal Title
  
  Cell Tissue Re3s 331
  
  Pages: 625-641
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592020
[Journal Article] The ruffled border and attachment regions of the apposing membrane of resorbing osteoclasts as visualized from the cytoplasmic face of the membrane2006
- Author(s)
  Akisaka, T., Yoshida H, Suzuki R.
- Journal Title
  
  J Electron Microsc (in press)
- NAID
  10018183301
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591848
[Journal Article] The ruffled border and attachment regions of the apposing membrane of resorbing osteoclasts as visualized from the cytoplasmic face of the membrane2006
- Author(s)
  Akisaka T et al.
- Journal Title
  
  J Electron Microscopy (未定)
- NAID
  10018183301
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591848
[Presentation] アパタトペレット面に吸収窩を形成する培養破骨細胞の膜面の裏打ち構造2012
- Author(s)
  明坂年隆
- Organizer
  第117回日本解剖日本学会
- Place of Presentation
  山梨大学(甲府)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] アパタイトペレット面に吸収窩を形成する培養破骨細胞の膜面の裏打ち構造2012
- Author(s)
  明坂年隆
- Organizer
  第117回日本解剖日本学会
- Place of Presentation
  山梨大学(甲府)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] アパタイトペッレト面に吸収窩を形成する培養破骨細胞の膜面構造2011
- Author(s)
  明坂年隆
- Organizer
  第71回日本解剖学会中部支部学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] 細胞剥離(unroofing)法を用いた凍結技法と電顕細胞化学2011
- Author(s)
  明坂年隆
- Organizer
  第2回日本組織細胞化学会ワークショップ
- Place of Presentation
  金沢(招待講演)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] The polarity of actin filaments within the podosome as osteoclast adhesion structures2011
- Author(s)
  Akisaka T
- Organizer
  第88回日本生理学会・第116回日本解剖学会合同大会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] 細胞剥離法を用いた凍結技法と電顕細胞化学2011
- Author(s)
  明坂年隆
- Organizer
  第52回日本組織細胞化学会
- Place of Presentation
  金沢大学(金沢)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] アパタイトペレット面に吸収窩を形成する培養破骨細胞の膜面構造2011
- Author(s)
  明坂年隆
- Organizer
  第71回日本解剖学会中部支部学術集会
- Place of Presentation
  名古屋大学(名古屋)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] 培養破骨細胞に出現するフリー微小管2010
- Author(s)
  明坂年隆, 他1名
- Organizer
  日本解剖学会
- Place of Presentation
  盛岡(岩手医科大学)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] HMM修飾による培養破骨細胞におけるアクチン線維の構成と極性についての凍結レプリカ超微構造解析2010
- Author(s)
  明坂年隆
- Organizer
  第52回日本歯科基礎医学会
- Place of Presentation
  タワーホール船橋(東京)
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] HMM修飾による培養破骨細胞におけるアクチン線維の構成と極性についての凍結レプリカ超微構造解析2010
- Author(s)
  明坂年隆, 他1名
- Organizer
  第52回歯科基礎医学会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] HMM修飾による培養破骨細胞におけるアクチン線維の構成と極性についての凍結レプリカ超微構造解析2010
- Author(s)
  明坂年隆
- Organizer
  第52回日本歯科基礎医学会
- Place of Presentation
  ホール船橋(東京)
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] 培養破骨細胞に出現するフリー微小管2010
- Author(s)
  明坂年隆
- Organizer
  第115回日本解剖学会
- Place of Presentation
  岩手県民会館(盛岡)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] アパタイトペレット面に吸収窩を形成する培養破骨細胞のポドゾームにおけるアクチン線維の構造とその極性2010
- Author(s)
  明坂年隆
- Organizer
  第70回日本解剖学会中部支部学術集会
- Place of Presentation
  じゅうろくプラザ(岐阜)
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] 破骨細胞に現れるnon-centrosomal微小管2009
- Author(s)
  明坂年隆
- Organizer
  第51回日本歯科基礎医学会
- Place of Presentation
  新潟コンベンションセンター(新潟)
- Year and Date
  2009-09-01
- Data Source
  KAKENHI-PROJECT-21592350
[Presentation] 破骨細胞に現れる non-centrosomal 微小管2009
- Author(s)
  明坂年隆, 他1名
- Organizer
  日本解剖学会
- Place of Presentation
  新潟(朱鷺メッセ)
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-21592350

1. YOSHIDA Hisaho (80102119)

# of Collaborated Projects: 11 results

# of Collaborated Products: 1 results
2. KOGAYA Yasutoku (30076046)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. SHIGA Hisataka (10076044)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SUZUKI Reiko (90333723)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 中島経夫 (60139938)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MITSUTERU Hosoi (00034190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AKISAKA Toshitaka 明坂 年隆

明坂 年隆 アキサカ トシタカ

TOSHITAKA Akisaka 明坂 年隆

Research Projects

Research Products

Co-Researchers

Ultra and molecular structures of the adhesive apparatus occurred in the osteoclastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Adhesion structures and their cytoskeleton-membrane interactions at podosomes as a specific signal transduction site of osteoclastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Podosome structures as a focal adhesion appeared in osteoclasts in culturePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CLATHRIN SHEETS AND CYTOSKELETAL STRCTURES ON THE PROTOPLASMIC SURAFCE OF THE VENTRAL MEMBRANES OF OSTEOCLASTS IN CULTUREPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The ultrastructure of osteoclast ruffled border and resorption lacuna

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clathrin sheets and cytoskeletal podosomes on the cytoplasmic side of ventral membranes of cultured osteoclastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Membrane associated clathrin sheets as a possible adhesion structure in cultured osteoclastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Visualization of acidic pH compartments on cultured osteoclastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

急速凍結軟骨基質における硫酸基の超微局在と石灰化

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of sulfated glycoconjugates ectodermally derived hard tissue formation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ultrastructural investigation of the membrane modifications of osteoclastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ultrastructure of bone resorption by osteoclastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 細胞剥離法で明らかになる培養破骨細胞の接着側細胞膜面の裏打ち構造2012

Author(s)

AKISAKA Toshitaka 明坂年隆

明坂年隆アキサカトシタカ

TOSHITAKA Akisaka 明坂年隆