KUNIMOTO Fumio 國元文生

Researcher Number	70125847
Other IDs
Affiliation (based on the past Project Information) *help	2013 – 2014: 群馬大学, 医学部附属病院, 准教授 2007 – 2012: Gunma University, 医学部, 准教授 2006: 群馬大学, 医学部, 助教授 1998 – 1999: 群馬大学, 医学部, 講師 1986 – 1987: 群馬大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Emergency medicine / Anesthesiology/Resuscitation studies Except Principal Investigator 麻酔学
Keywords	Principal Investigator 敗血症 / 脂肪酸代謝 / 糖代謝 / 心機能 / FABP4 / FABP5 / 鎮静薬 / 重症患者 / サイトカイン / 集中治療 … More / apoptosis / 免疫抑制 / 免疫抑制作用 / 毛細血管内皮細胞 / PPARγ / 心不全 / エネルギー代謝 / 脂肪酸 / グルコース / ノックアウトマウス / 心臓手術 / 体外循環 / エンドトキシン / 静脈血酸素飽和度 / ケトン体比 / 胃粘膜pH / 肝静脈血酸素飽和度 / 動脈血ケトン体比 / 心拍出量 / 肝静脈酸素飽和度 / エンドスペシー / ベータグルカン / cardiopulmonary bypass / endotoxin / cardiac output / venous oxygen saturation / ketone body ratio / gastric intramucosal pH … More Except Principal Investigator 虚血と再還流 / 細胞機能障害 / 過酸化脂質 / ショック.スーパーオキシドデイスムターゼ / 酸素遊離基 / ショック / 細胞障害 / スーパーオキシドデイスムターゼ / 虚血 / 再循環 / 活性酸素 / 化学発光 / キサンチン酸化酵素 / スーパーオキシドディスムターゼ / 脳虚血 / 内臓虚血 / Ischemia and reperfusion / cellular injury / lipoperoxide Less

Enhanced glucose metabolism improves cardiac function and survival rate during severe sepsisPrincipal Investigator
- Principal Investigator
  
  KUNIMOTO Fumio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Gunma University
A role of capillary endothelial cells in pathophysiology of sepsis ; basic study by using endothelial-specific PPAR. knockout micePrincipal Investigator
- Principal Investigator
  
  KUNIMOTO Fumio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Gunma University
Evaluation of expression of NF-κB DNA and cytokine production in whte bold cells derived from sedative patientsPrincipal Investigator
- Principal Investigator
  
  KUNIMOTO Fumio
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Gunma University
A study of splanchnic circulation and gastrointestinal mucosal function in critically ill patients.Principal Investigator
- Principal Investigator
  
  KUNIMOTO Fumio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Gunma University
The mechanism of cellular dysfunction after ischemia and reperfusion
- Principal Investigator
  
  OGAWA Ryo
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  麻酔学
- Research Institution
  Nippon Medical School
  Gunma University

All 2014 2013 2012 2010 2008

All Journal Article Presentation

[Journal Article] 神経芽腫、肝腫瘍による腹部コンパートメント症候群に対する周術期管理の1症例2014
- Author(s)
  柳澤晃広, 戸部賢, 日野原宏, 国元文生, 高澤知規, 齋藤繁
- Journal Title
  
  麻酔
  
  Volume: 63 Pages: 184-187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592730
[Journal Article] PPARgamma in Capillary Endothelia Promotes Fatty Acid Uptake by Heart During Long-term Fasting.2013
- Author(s)
  Goto K, Iso T, Hanaoka H, Suga T, Hattori A, Irie Y, Shinagawa Y, Matsui H, Syamsunarno MRAA, Matsui M, Haque A, Arai M, Kunimoto F, Yokoyama T, Endo K, Gonzalez FJ, Kurabayashi M.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 2(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592730
[Journal Article] 術後の血管系合併症-その診断と対策　術後の肺動脈塞栓　治療のコツ2013
- Author(s)
  猪瀬崇徳,宮崎達也,鈴木茂正,田中成岳,国元文生,桑野博行
- Journal Title
  
  臨床外科
  
  Volume: 68（2） Pages: 158-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592730
[Journal Article] Comparative effects of flurbiprofen and fentanyl on natural killer cell cytotoxicity, lymphocyte subsets and cytokine concentrations in post-surgical intensive care unit patients: prospective, randomized study.2013
- Author(s)
  Narahara H, Kadoi Y, Hinohara H, Kunimoto F, Saito S.
- Journal Title
  
  J Anesth.
  
  Volume: 27 Pages: 676-683
- DOI
  10.1007/s00540-013-1597-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592730, KAKENHI-PROJECT-25670664
[Journal Article] 【今知りたい!集中治療の最新論点-Pro & Conディベート-】栄養　栄養管理に中心静脈栄養法は不要である?2013
- Author(s)
  巽博臣, 今泉均, 升田好樹, 吉田真一郎, 坂脇英志, 後藤京子, 高橋科那子, 山蔭道明, 大川牧生, 国元文生
- Journal Title
  
  救急・集中治療
  
  Volume: 25 Pages: 1194-1200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592730
[Journal Article] Perioperative nutriture in esophageal cancer patients undergoing esophagectomy.2013
- Author(s)
  Kobayashi T, Oshima K, Yokobori T, Idetsu A, Hayashi Y, Hinohara RN, Miyazaki T, Kunimoto F, Kato H, Kuwano H.
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 60 Pages: 1311-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592730
[Journal Article] 乳癌の抗癌薬によるアナフィラキシー様反応により呼吸不全を生じ、ECMO使用により救命できた1例2013
- Author(s)
  柳澤晃広,金本匡史,久保和弘,日野原宏, 国元文生,齋藤　繁
- Journal Title
  
  臨床麻酔
  
  Volume: 37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592730
[Journal Article] ICU患者における血清マグネシウムイオン値と重症度の関連2012
- Author(s)
  楢原創,金本匡史,大川牧生,日野原宏,国元文生,齋藤繁
- Journal Title
  
  ICUとCCU
  
  Volume: 36（6） Pages: 445-450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592730
[Journal Article] Necrotizing fasciitis following psoas muscle abscess caused by hypermucoviscous Klebsiella pneumoniae.2012
- Author(s)
  Mita N, Narahara H, Okawa M, Hinohara H, Kunimoto F, Haque A, Saito S, Oshima K.
- Journal Title
  
  J Infect Chemother
  
  Volume: 18(4) Pages: 565-8
- NAID
  10030948251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592730
[Journal Article] Effects of the cannabinoid antagonist AM281 on systemic hemodynamics and mortality rate in streptozotocin- induced diabetic rats with endotoxic shock-Comparison between non-diabetic and diabetic rats2008
- Author(s)
  Kadoi Y, Hinohara H, Kunimoto F, Saito S
- Journal Title
  
  Acta Anaesthesiol. Scand 52
  
  Pages: 664-672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591977
[Journal Article] Comparative effects of propofol versus dexmedetomidine on cerebrovascular carbon dioxide reactivity in patients with septic shock2008
- Author(s)
  Kadoi Y, Saito S, Kawauchi C, Hinohara H, Kunimoto F
- Journal Title
  
  British Journal of anesthesia 100
  
  Pages: 224-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591977
[Journal Article] Comparative effects of propofol versus dexmedetomidine on cerebrovascular carbon dioxide reactivity in patients with septic2008
- Author(s)
  Kadoi Y, Saito S, Kawauchi C, Hinohara H, Kunimoto F
- Journal Title
  
  shock. Br. J Anesth 100
  
  Pages: 224-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591977
[Journal Article] Evaluation of cerebrovascular carbon dioxide reactivity in patients with diabetes mellitus under sedative doses of propofol2008
- Author(s)
  Kawauchi C, Kadoi Y, Hinohara H, Kunimoto F, Saito S
- Journal Title
  
  J Anesthesia 22
  
  Pages: 429-434
- NAID
  10024460901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591977
[Journal Article] Effects of the cannabinoid antagonist AM281 on systemic hemodynamics and mortality rate in streptozotocin- induced diabetic rats with endotoxic shock- Comparison between non-diabetic and diabetic rats2008
- Author(s)
  Kadoi Y, Hinohara H, Kunimoto F, Saito S
- Journal Title
  
  Acta Anaesthesiolica Scandinavica 52
  
  Pages: 664-672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591977
[Presentation] ICU患者の急性期投与エネルギー量は20～25kcal/kgも必要ない2014
- Author(s)
  国元文生
- Organizer
  第41回日本集中治療医学会学術集会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-24592730
[Presentation] Oral Assesment Sheetを用いた口腔ケア回診での口腔スコアの経時的変化と課題2014
- Author(s)
  福士宙之,神山治郎,柳澤晃広,河内奈穂美,楢原創,金本匡史,戸部賢,日野原宏,根岸明秀,国元文生
- Organizer
  第41回日本集中治療医学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24592730
[Presentation] 重症患者栄養管理のエビデンスとプラクティス2013
- Author(s)
  国元文生
- Organizer
  第40回　日本集中治療医学会学術集会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-24592730
[Presentation] 塩酸ピルジカイニド中毒により心室頻拍を呈した1例2013
- Author(s)
  村田将人,萩原周一,金子稔,青木誠,古川和美,中村卓郎,大山良雄,田村遵一,国元文生,大嶋清宏
- Organizer
  第40回　日本集中治療医学会学術集会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-24592730
[Presentation] プロカルシトニン（PCT）値と各種細菌培養結果との検討2013
- Author(s)
  柳澤晃広,福士宙之,神山治郎,楢原創,金本匡史,久保和宏,戸部賢,日野原宏,門井雄司,国元文生,齋藤繁
- Organizer
  第22回日本集中治療医学会関東甲信越地方会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-24592730
[Presentation] L-FABPによる腎機能低下の早期診断における有用性2013
- Author(s)
  柳澤晃広,楢原創,金本匡史,大川牧生,戸部賢,高澤知規,日野原宏,門井雄司,国元文生,齋藤繁
- Organizer
  第40回　日本集中治療医学会学術集会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-24592730
[Presentation] A possible role of transendothelial glycerol transport through aquaporin 7 regulated by peroxisome proliferated activator reveptor-gamma2010
- Author(s)
  Haque A., Iso T.,Kunimoto F.,Saito S.,Kurabayashi M.
- Organizer
  XX^<th> World Congress International Society for Heart Research (ISHR)
- Place of Presentation
  Kyoto
- Year and Date
  2010-05-16
- Data Source
  KAKENHI-PROJECT-21592303
[Presentation] 集中治療患者のヘモグロビン濃度2008
- Author(s)
  日野原宏、河内力、金丸良範、林淑朗、大嶋清宏、門井雄司、桑野博行、國元文生
- Organizer
  第35回日本集中治療医学会
- Place of Presentation
  東京
- Year and Date
  2008-03-01
- Data Source
  KAKENHI-PROJECT-18591977

1. ISO Tatsuya (10400756)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. KADOI Yuji (10292591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. OGAWA Ryo (20008345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 齊藤繁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUNIMOTO Fumio 國元 文生

Research Projects

Research Products

Co-Researchers

Enhanced glucose metabolism improves cardiac function and survival rate during severe sepsisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A role of capillary endothelial cells in pathophysiology of sepsis ; basic study by using endothelial-specific PPAR. knockout micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of expression of NF-κB DNA and cytokine production in whte bold cells derived from sedative patientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study of splanchnic circulation and gastrointestinal mucosal function in critically ill patients.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of cellular dysfunction after ischemia and reperfusion

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 神経芽腫、肝腫瘍による腹部コンパートメント症候群に対する周術期管理の1症例2014

Author(s)

Journal Title

Data Source

[Journal Article] PPARgamma in Capillary Endothelia Promotes Fatty Acid Uptake by Heart During Long-term Fasting.2013

Author(s)

Journal Title

Data Source

[Journal Article] 術後の血管系合併症-その診断と対策 術後の肺動脈塞栓 治療のコツ2013

Author(s)

Journal Title

Data Source

[Journal Article] Comparative effects of flurbiprofen and fentanyl on natural killer cell cytotoxicity, lymphocyte subsets and cytokine concentrations in post-surgical intensive care unit patients: prospective, randomized study.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 【今知りたい!集中治療の最新論点-Pro & Conディベート-】 栄養 栄養管理に中心静脈栄養法は不要である?2013

Author(s)

Journal Title

Data Source

[Journal Article] Perioperative nutriture in esophageal cancer patients undergoing esophagectomy.2013

Author(s)

Journal Title

Data Source

[Journal Article] 乳癌の抗癌薬によるアナフィラキシー様反応により呼吸不全を生じ、ECMO使用により救命できた1例2013

Author(s)

Journal Title

Data Source

[Journal Article] ICU患者における血清マグネシウムイオン値と重症度の関連2012

Author(s)

Journal Title

Data Source

[Journal Article] Necrotizing fasciitis following psoas muscle abscess caused by hypermucoviscous Klebsiella pneumoniae.2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Effects of the cannabinoid antagonist AM281 on systemic hemodynamics and mortality rate in streptozotocin- induced diabetic rats with endotoxic shock-Comparison between non-diabetic and diabetic rats2008

Author(s)

Journal Title

Data Source

[Journal Article] Comparative effects of propofol versus dexmedetomidine on cerebrovascular carbon dioxide reactivity in patients with septic shock2008

Author(s)

Journal Title

Data Source

KUNIMOTO Fumio 國元文生

[Journal Article] 術後の血管系合併症-その診断と対策　術後の肺動脈塞栓　治療のコツ2013

[Journal Article] 【今知りたい!集中治療の最新論点-Pro & Conディベート-】栄養　栄養管理に中心静脈栄養法は不要である?2013