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HARA Atsushi  原 厚

ORCIDConnect your ORCID iD *help
Researcher Number 70126697
Other IDs
Affiliation (based on the past Project Information) *help 2010 – 2012: 信州大学, 医学系研究科, 准教授
1999 – 2002: 信州大学, 医学部, 講師
1997: SHINSHU UNIVERSITY,LECTURER, 医学部附属加齢適応研究センター, 講師
1996 – 1997: 信州大学, 医学部・附属加齢適応研究センター, 講師
1995 – 1996: 信州大学, 医学部, 講師 … More
1994 – 1995: 信州大学, 医学部・加齢適応研究センター, 講師
1993: 信州大学, 医学部, 講師
1992: Assistant Professor, Department of Lipid Biochemistry, Shinshu University School, 医・心脈管病研, 講師
1992: 信州大学, 医学部・心臓管病研, 講師
1990 – 1991: 信州大学, 医学部・附属心脈管病研究施設, 講師
1990: 信州大学, 医学部・心脈管病研究施設, 講師
1988: Institute of Cardiovascular Disease, Shinshu University School of Medicine, 医学部附属心脈管研究施設, 講師
1986 – 1988: 信州大学, 医学部附属心脈管病研究施設, 講師 Less
Review Section/Research Field
Principal Investigator
General medical chemistry
Except Principal Investigator
Biological Sciences / Neurochemistry/Neuropharmacology / Pathological medical chemistry / Pathological medical chemistry / 物質生物化学
Keywords
Principal Investigator
高インスリン血症 / 糖尿病 / ペルオキシソーム増殖剤活性化受容体 / LDL受容体 / 肥満 / 膵臓 / 白色脂肪組織 / 肝臓 / 糖尿症 / sulfatide … More / anticoagulant / fibrinogen / prothrombin time / thrombin / bieeding time / platelet / sulfdtide / anticodgulant / Prothrombin time / bleeding time / Pldtelet / Sulfatide / dnticoagulant / Platelet / SULFATIDE / ANTICOAGULANT / FIBRINOGEN / PROTHROMBIN TIME / THROMBIN / BLEEDING TIME / PLATELET … More
Except Principal Investigator
糖脂質 / 神経突起 / ガングリオシド / 神経芽細胞腫 / 細胞増殖 / 糖脂質生合成 / スルファチド / PPAR / LDL / スフィンゴ脂質 / 神経細胞 / 細胞分化 / C型肝炎 / コア蛋白 / 肝発癌 / ミトコンドリア膨満 / 脂肪肝 / 酸化ストレス / 遺伝性高脂血症 / WHHLウサギ / 動脈硬化 / 神経芽腫細胞 / 細胞周期 / sphingolipid / neuroblastoma cell / neurite / cell cycle / PPARα / 膜輸送系 / 血液凝固阻害作用 / フィブリノーゲン / リポタンパク質 / 癌 / ウィルス / シグナル伝達 / 核内受容体 / アポトーシス / 長鎖脂肪酸 / C型肝炎ウイルス / 多中心性 / トランスジェニックマウス / レトロウイルス / 分子腫瘍学 / C 型肝炎 / アンタゴニスト / 中性脂肪 / HCVコア蛋白 / HCC / フィブレート / EPA / PPAR活性化 / ミトコンドリア障害 / フィブラート / スフィンゴリピドーシス / Krabbe病 / Gaucher病 / Niemann-Pick病 / リゾスフィンゴリピド / ガラクトサイコシン / グルコサイコシン / スフィンゴシルホスフォリルコリン / 抗動脈硬化作用 / 抗血液凝固作成 / 糖転移酵素 / Glycosphingolipid / Glycolipid biosynthesis / Sphingolipid / Ganglioside / Neuroblastoma cell / Neurite outgrowth / Cell differentiation / Cell growth / スフィンゴシン / プロテインキナーゼ / カルモジュリン / プロテインナーゼ / スフィンゴンン / sphingosine / glycolipid / protein kinase / calmodulin / C型肝炎ウイルス・コア蛋白 / CuZnSOD / β酸化酵素 / 繊維化 / Mitochondria swelling / Hepatitis C virus core protein / Fatty liver / Cu Zu SOD / Oxidative stress / βOxidation enzymes / Fibrosis / スフィンゴ糖脂質 / レクチン / フローサイトメトリー / 神経芽腫再法 / 細胞表面糖鎖 / glycosphingolipid / ganglioside / lectin / flow cytometry / WHHLーrabbits / 動脈硬化症 / 泡沫細胞 / 血清脂質 / リポタン白質 / 動脈壁脂質 / コレステロール / コレステロール・エステル / LysoPC / WHHL-rabbit / コレステロール結晶沈着 / スフィンゴミエリン / エタノールアミン・プラスマロゲン / スティンゴ糖脂貭 / 脂肪酸 / 長鎖塩基 / 動脈硬化性病変 / 酸性糖脂質 / Anti-atherosclerotic effect / Atherosclerosis / Foam cells / Lysophosphatidylcholine / Macrophage / Smooth muscle cell / Sulfatide Less
  • Research Projects

    (15 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (6 People)
  •  Development of prevention methods for hepatitis C - related liver tumor focusing function of nuclear receptor PPAR

    • Principal Investigator
      AOYAMA Toshifumi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Shinshu University
  •  C型肝炎ウイルス感染による多中心的肝発癌に対する新たな予防法の開発

    • Principal Investigator
      青山 俊文
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Shinshu University
  •  C型肝炎ウイルス・コア蛋白による多中心的肝癌発生機構の解明

    • Principal Investigator
      AOYAMA Toshifumi
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Shinshu University
  •  核内受容体を介したインスリン分泌および肥満調節機構の解明Principal Investigator

    • Principal Investigator
      原 厚
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Shinshu University
  •  Elucidation of mechanisms of steatosis and inflammation by alcohol ingestion or HCV core protein

    • Principal Investigator
      AOYAMA Toshifumi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Shinshu University
  •  Roles of sphingolipids and glycosphingolipids in neurite extension, adhesion and growth of neuronal cells.

    • Principal Investigator
      UEMURA Kei-ichi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Shinshu University
  •  ANTICOAGULANT ACTIVITY OF SULFATIDE AND ITS EFFECTS ON ARTERIOSCLEROSISPrincipal Investigator

    • Principal Investigator
      HARA Atsushi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      SHINSHU UNIVERSITY
  •  Sphingolipids which regulate the cell functions in neuronal cells.

    • Principal Investigator
      UEMURA Kei-ichi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Shinshu University
  •  血清リポタンパク質酸性糖脂質の分子認識と接着

    • Principal Investigator
      武富 保
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Shinshu University
  •  ガングリオシドによる神経細胞膜輸送系の調節の機構

    • Principal Investigator
      上村 敬一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Shinshu University
  •  ガングリオシドによる神経細胞膜輸送系の調節の機構

    • Principal Investigator
      UEMURA Kei-ichi
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Shinshu University
  •  The regulation of expression and function of glycoshingolipids on cell surfaces with an inhibitor of glucosylceramide synthesis.

    • Principal Investigator
      UEMURA Kei-ichi
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Shinshu University
  •  動脈硬化症における血管壁の脂質代謝と血清リポタン白質の作用

    • Principal Investigator
      武富 保
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Shinshu University
  •  スフィンゴリピドーシスの病因病態解析の基礎的研究

    • Principal Investigator
      武富 保
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Shinshu University
  •  Basic Research on Lipid Metabolism in Atherosclerosis

    • Principal Investigator
      TAKETOMI Tamotsu
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Shinshu University

All 2012

All Journal Article

  • [Journal Article] Hepatic cerebroside sulfotransferase is induced by PPARα activation in mice2012

    • Author(s)
      Kimura T, Nakajima T, Kamijo Y, Tanaka N, Wang L, Hara A, Sugiyama E, Tanaka E, Gonzalez FJ, Aoyama T
    • Journal Title

      PPAR Res

      Volume: 2012 Pages: 174932-174932

    • DOI

      10.1155/2012/174932

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390060
  • [Journal Article] Long-term improvement of oxidative stress via kidney transplantation ameliorates serum sulfatide levels.2012

    • Author(s)
      Kamijo Y, Wang LX, Matsumoto A,Nakajima T, Hashimoto K, Higuchi M, Kyogashima M, Aoyama T, Hara A
    • Journal Title

      Clin Exp Nephrol

      Volume: 16 Pages: 959-967

    • DOI

      10.1007/s10157-012-0634-2

    • NAID

      10031145928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390060
  • [Journal Article] PPAR α activation protects against anti-Thy1 nephritis by suppressing glomerular NF-κB signaling.2012

    • Author(s)
      Hashimoto K, Kamijo Y, Nakajima T, Harada M, Higuchi M, Ehara T, Shigematsu H, Aoyama T
    • Journal Title

      PPAR Res.

      Volume: 2012 Pages: 1-11

    • DOI

      10.1155/2012/976089

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390060, KAKENHI-PROJECT-22590238
  • [Journal Article] Attenuation of Kidney Injuries Maintains Serum Sulfatide Levels Dependent on Hepatic Synthetic Ability: A Possible Involvement of Oxidative Stress2012

    • Author(s)
      Sheng XN, Nakajima T, Wang LX, Zhang XW, Kamijo Y, Takahashi K, Tanaka N, Sugiyama E, Kyogashima M, Aoyama T, Hara A
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 227 Issue: 1 Pages: 1-12

    • DOI

      10.1620/tjem.227.1

    • NAID

      10030613055

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390060
  • 1.  UEMURA Kei-ichi (80012756)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  TAKETOMI Tamotsu (30020704)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  AOYAMA Toshifumi (50231105)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 4 results
  • 4.  NASU Tamie (10020794)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  岡野 照 (30020803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KAMIJO Yuji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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