Zeniya Mikio 銭谷幹男

… Alternative Names

ZENIYA Mikio 銭谷幹男

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Researcher Number	70138767
Other IDs
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Affiliation (Current)	2022: 国際医療福祉大学, 臨床医学研究センター, 教授
Affiliation (based on the past Project Information) *help	2011 – 2012: 東京慈恵会医科大学, 医学部, 教授 2007 – 2008: Jikei University School of Medicine, 医学部, 教授 2006: 東京慈恵会医科大学, 医学部, 助教授 1994 – 2004: 東京慈恵会医科大学, 医学部, 助教授 2003: Jikei University School of Medicine, Assistant Professor, 医学部, 助教授 … More 1993: 東京慈恵会医科大学, 医学部・第一内科, 講師 1993: The Jikei University School of Medicine, First Department of Internal Medicine,, 第一内科, 講師 1992 – 1993: 東京慈恵会医科大学, 医学部, 講師 1991: 東京慈恵会医科大学, 第一内科, 講師 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology / Public health/Health science
Keywords	Principal Investigator 自己免疫性肝炎 / IL-12 / AIH / Fas / bcl-2 / TCRレパトア / 原発性胆汁性肝硬変 / Th1 / 樹状細胞 / PBC … More / 免疫寛容破綻 / 自己反応性T細胞 / 肝移行性 / 補助分子 / 接着分子 / アポトーシス / 自己反応性CD8細胞 / 肝内免疫環境 / 類洞内皮細胞 / 星細胞 / マクロファージ / アシアロ糖蛋白受容体 / T細胞受容体Vβレパトア / T細胞受容体Vbetaレパトア / annexin / 漫性肝炎 / 免疫学的肝障害 / Autoimmune hepatitis / Asialoglycoprotein receptor / T cell receptor / T cell receptor gene subfamily(Vbeta) / T細胞受容体Vβ鎖 / 免疫複合体 / bcl / Fas抗原 / 慢性肝炎 / bc1 / TCRVβ / FACS / autoimmune hepatitis / T-cell receptor / immune coplex / hepatitis C / Th_1 / Th_2バランス / Vβ7 / 肝内サイトカイン発現 / 慢性C型肝炎 / Th2バランス / 原発生胆汁性肝硬変 / Th2プロフィール / 細胞質内サイトカイン発現 / Autoimmune Hepatitis / Th2 balance / TCR reperatoire / Vbeta7 / 融合樹状細胞 / 肝内T細胞浸潤 / HLA-DR4 / CD25 / DR4 / 肝癌細胞 / 融合細胞 / 実験的自己免疫性肝炎 / 細胞障害性T細胞 / AUTOIMMUNE HEPATITIS / ANIMAL MODEL / DENDRITIC CELL / 実験モデル / 胆管細胞 / 動物モデル / 自己抗原 / DC / 調節性細胞 / PDC-E2 / Animal Model / Dendritic cell / Regulatory cell … More Except Principal Investigator 自己免疫性肝炎 / 内皮細胞抗体 / ヘパリン / 類洞壁内皮細胞 / スルファチド / NKT / CTLA-4 / IFN-γ / 脂肪肝 / 動脈硬化 / リスクスコア / 糖尿病 / リスクスコア　フィンランド / HbA1c / 危険因子 / 肝類洞壁内皮細胞 / 慢性肝炎 / 内皮細胞障害 / 血管内皮細胞 / ヘパラン硫酸 / 類洞壁内皮細胞抗体 / Hepatic sinusoidal endothelial cell / Autoimmune hepatitis / Anti-endothelial cell antibody / Heparin / Chronic hepatitis / 類洞壁内原細胞 / 類洞内皮細胞 / 内皮細胞 / 自己抗体 / 肝類洞内皮細胞 / autoimmune hepatitis / hepatic sinusoidal endothelial cell / endothelial cell antibody / antisulfatide antibody / heparin / 原発性胆汁性肝改変 / Vα24 / CD1d / CD1b / CDLd / Vα24JαQ / AUTOIMMUNE HEPATITIS / TOLERANCE / 原発性胆汁性肝硬変 / 遺伝子多型 / 疾患感受性遺伝子 / AIH / PEC / POLYMORPHISM / 肝免疫 / 経口寛容 / 調節性細胞 / 経口寛容誘導 / 肝内免疫環境 / 活性化リンパ球 / アポトーシス / IL-10・IL-12 / 肝内類洞内皮細胞 / 肝内樹状細胞 / ORAL TOLERANCE / LIVER / REGURATORY CELL Less

自己免疫性肝疾患発症に関わる肝内炎症惹起性の肝・脾多段階的免疫寛容誘導破綻の解析Principal Investigator
- Principal Investigator
  
  銭谷幹男
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine
New predictiveindex for atherosclerosis with new risk factors
- Principal Investigator
  
  KATOH Shuichi
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  Jikei University School of Medicine
Mechanisms of the breakdown of antigen specific immunotolerance in autoimmune hepatitisPrincipal Investigator
- Principal Investigator
  
  ZENIYA Mikio
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine
ANALYSIS OF THE PATHOGENESIS OF PRIMARY BILIARY CIRRHOSIS BY USING ANIMAL MODEL THAT IS ESTABLISHED BY MULTI STEP BREAKING OF TOLERANCEPrincipal Investigator
- Principal Investigator
  
  ZENIYA Mikio
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JIKEI UNIVERSITY SCHOOL OF MEDICINE
THE ROLE OF THE LIVER FOR THE INDUCTION OF ORAL TOLERANCE.
- Principal Investigator
  
  TAKAHASHI Hiroki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine
IDENTIFICATION OF NEW NON-HLA DISEASE SUESEPUTABILITY GENE OF AUTOIMMUNE HEPATITIS
- Principal Investigator
  
  WATANABE Fumitoki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JIKEI UNIVERSITY SCHOOL OF MEDCINE
ESTABLISHMENT OF AUTOIMMUNE HEPATITIS MODEL BY USING FUSION CELL OF HEPATOCYTE AND DENDRITIC CELL.Principal Investigator
- Principal Investigator
  
  ZENIYA Mikio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine
PRESENTATION OF SULFACHID ANTIGEN BY INTRAHEPATIC CD1b POSITIVE ANTIGEN PRESENTING CELL OF AUTOIMMUNE HEPATITIS.
- Principal Investigator
  
  TAKAHASHI Hiroki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JIKEI UNIVERSITY SCHOOL OF MEDCINE
MOCECULAR MECHANISMS OF HEPATOCYTOTOXICITY IN AUTOIMMUNE LIVER DISEASESPrincipal Investigator
- Principal Investigator
  
  ZENIYA Mikio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The JIKEI University School of Medicine
Mechanism of hepatocyte injury in autoimmune hepatitis : involvement of hepatic sinusoidal endothelial cell injury.
- Principal Investigator
  
  TODA Gotaro
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The Jikei University School of Medicine
IMMUNO-REGULATION OF AUTO-REACTIVELIVER-INFILTRATE LYMPHOCYTE AND ITS RELATION TO APOPTOSIS IN AUTOMMUNE HEPATITIS.Principal Investigator
- Principal Investigator
  
  ZENIYA Mikio
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The Jikei University School of Medicine
The pathophisiologic role of hepatic lectin (asialoglycoprotein receptor) on immune mdiated liver cell injury in chronic liver diseases.Principal Investigator
- Principal Investigator
  
  ZENIYA Mikio
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The JIKEI University School of Medicine
IgG class antibody to hepatic endothelial cell in sera of patients with autoimmune hepatitis and its pathophysiological significance
- Principal Investigator
  
  TODA Gotaro
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The Jikei University School of Medicine

All 2013 2012 2011 2008

All Journal Article Presentation

[Journal Article] Cross sectional analysis of the Japanese Diabetes Risk Score in 4017 Japanese people and its clinical interpretation.2012
- Author(s)
  Katoh S, Zeniya M, Sakamoto Y, Utsunomiya K
- Journal Title
  
  Minerva Endocrinologica.
  
  Volume: 37(4) Pages: 6-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590609
[Journal Article] Cross sectional analysis of the Japanese Diabetes Risk Score in 4017 Japanese people and its clinical interpretation.2012
- Author(s)
  Katoh S, Zeniya M, Sakamoto Y, Utsunomiya K.
- Journal Title
  
  Minerva Endocrinologica
  
  Volume: 37(4) Pages: 6-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590609
[Journal Article] Characteristics of autoimmune hepatitis in the Asia-Pacific2012
- Author(s)
  Zeniya M.　Takahashi H
- Journal Title
  
  Hepatol Int
  
  Volume: 6 Pages: 342-349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590994
[Journal Article] Acute presentation of autoimmune hepatitis: Does it exist? A published work review2011
- Author(s)
  Takahashi H, Zeniya M.
- Journal Title
  
  Hepatol Res.
  
  Volume: 41 Pages: 498-504
- NAID
  10031144117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590994
[Journal Article] 自己免疫性肝炎の診断におけるスコアリングシステムの位置付け2011
- Author(s)
  高橋宏樹　銭谷幹男
- Journal Title
  
  日本消化器病学会誌
  
  Volume: 108 Pages: 1838-1844
- NAID
  10030298660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590994
[Presentation] Japanese Diabetes Risk Scoreにおける糖尿病発症予測、尿中微量アルブミン値予測の検証および脂肪肝の指標との比較検討.2013
- Author(s)
  加藤秀一、銭谷幹男、阪本要一、宇都宮一典.
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22590609
[Presentation] Japanese Diabetes Risk Scoreにおける糖尿病発症予測、尿中微量アルブミン値予測の検証および脂肪肝の指標との比較検討2013
- Author(s)
  加藤秀一、銭谷幹男、阪本要一、宇都宮一典
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22590609
[Presentation] Retrospective analysis of the Japanese Diabetes Risk Score for incident diabetes and urinary albumin excretion in 2084 subjects and comparison with fatty liver markers.2013
- Author(s)
  S. Katoh, H. Takahashi, M. Kaji, M. Zeniya, Y. Sakamoto, K. Utsunomiya
- Organizer
  49th Annual Meeting of the European Association for the Study of Diabetes (欧州糖尿病学会)
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22590609
[Presentation] Cross sectional analysis of the Japanese Diabetes Risk Score in 4017 Japanese people and its clinical interpretation.2012
- Author(s)
  Katoh S, Zeniya M, Sakamoto Y, Utsunomiya K.
- Organizer
  7th World Congress on Prevention of Diabetes and its Complications.
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-22590609
[Presentation] Cross sectional analysis of the Japanese Diabetes Risk Score in 4017 Japanese people and its clinical interpretation2012
- Author(s)
  Katoh S, Zeniya M, Sakamoto Y, Utsunomiya K
- Organizer
  7th World Congress on Prevention of Diabetes and its Complications
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-22590609
[Presentation] 人間ドック受診者4017例におけるJapanese Diabetes Risk Scoreの横断的研究とその臨床的な解釈.2012
- Author(s)
  加藤秀一、銭谷幹男、阪本要一、宇都宮一典.
- Organizer
  第53回日本人間ドック学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590609
[Presentation] 人間ドック受診者4017例におけるJapanese Diabetes Risk Scoreの横断的研究とその臨床的な解釈2012
- Author(s)
  加藤秀一、銭谷幹男、阪本要一、宇都宮一典.
- Organizer
  第53回日本人間ドック学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590609
[Presentation] HbA1c(JDS 値)新基準による糖尿病診断率の変化に関する検討2011
- Author(s)
  加藤秀一、高橋宏樹、和田高士、銭谷幹男、阪本要一、宇都宮一典
- Organizer
  第52回日本人間ドック学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590609
[Presentation] 自己免疫性肝炎の発症機構と病態(シンポジウム)2008
- Author(s)
  高橋宏樹, 銭谷幹男
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-18590751

1. TODA Gotaro (40090500)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. TAKAHASHI Hiroki (80256403)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. AIZAWA Yoshio (90147273)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. WATANABE Fumitoki (90231711)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KUNIYASU Yushi (10338890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. AMANO Katausi (70424645)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KATOH Shuichi (00333071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. SAKAMOTO Yoichi (00119801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. UTSUNOMIYA Kazunori (50185047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
10. ISHIKAWA Tomohisa (10260944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 林昭太 (80287276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Zeniya Mikio 銭谷 幹男

ZENIYA Mikio 銭谷 幹男

Research Projects

Research Products

Co-Researchers

自己免疫性肝疾患発症に関わる肝内炎症惹起性の肝・脾多段階的免疫寛容誘導破綻の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New predictiveindex for atherosclerosis with new risk factors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of the breakdown of antigen specific immunotolerance in autoimmune hepatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ANALYSIS OF THE PATHOGENESIS OF PRIMARY BILIARY CIRRHOSIS BY USING ANIMAL MODEL THAT IS ESTABLISHED BY MULTI STEP BREAKING OF TOLERANCEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

THE ROLE OF THE LIVER FOR THE INDUCTION OF ORAL TOLERANCE.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IDENTIFICATION OF NEW NON-HLA DISEASE SUESEPUTABILITY GENE OF AUTOIMMUNE HEPATITIS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ESTABLISHMENT OF AUTOIMMUNE HEPATITIS MODEL BY USING FUSION CELL OF HEPATOCYTE AND DENDRITIC CELL.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PRESENTATION OF SULFACHID ANTIGEN BY INTRAHEPATIC CD1b POSITIVE ANTIGEN PRESENTING CELL OF AUTOIMMUNE HEPATITIS.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MOCECULAR MECHANISMS OF HEPATOCYTOTOXICITY IN AUTOIMMUNE LIVER DISEASESPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of hepatocyte injury in autoimmune hepatitis : involvement of hepatic sinusoidal endothelial cell injury.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IMMUNO-REGULATION OF AUTO-REACTIVELIVER-INFILTRATE LYMPHOCYTE AND ITS RELATION TO APOPTOSIS IN AUTOMMUNE HEPATITIS.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The pathophisiologic role of hepatic lectin (asialoglycoprotein receptor) on immune mdiated liver cell injury in chronic liver diseases.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IgG class antibody to hepatic endothelial cell in sera of patients with autoimmune hepatitis and its pathophysiological significance

Principal Investigator

Project Period (FY)

Zeniya Mikio 銭谷幹男

ZENIYA Mikio 銭谷幹男