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YOSHINO Kazuo  吉野 和夫

ORCIDConnect your ORCID iD *help
Researcher Number 70143964
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2010 – 2012: 信州大学, 理学部, 教授
2003: Shinsyu University, Department of Chemistry, Assoc.Prof., 理学部, 助教授
1996 – 2003: 信州大学, 理学部, 助教授
1988 – 1994: 信州大学, 理学部, 助手
Review Section/Research Field
Principal Investigator
Nuclear engineering / 分析・地球化学
Except Principal Investigator
Dermatology / Nuclear engineering
Keywords
Principal Investigator
^<11>B-NMR / DHICA / DHI / 悪性黒色腫 / p-ボロノフェニルアラニン / 中性子捕捉療法(BNCT) / メラニン / 悪性黒色腫(メラノーマ) / 中性子捕捉療法 / Melanin Precursor … More / Melanin / Boron Neutron Capture Therapy / Melanoma / p-BPA / 5-S-システニルドーパ / メラニンモノマー / フェオメラニン / ユウメラニン / m-ボロノフェニルアラニン / 中性子補足療法(NCT) / エピネフリン / ノルエピネフリン / ドーパミン / 中性子捕捉療法(NCT) / メラニン前駆体 / p-ボロノフェニルアラニン(p-BPA) / p-Boronophenylalanine-tyrosine dipeptide / melanin / p-Boronophenylalanine / melanoma / ィイD111ィエD1B-NMR / Boron Neutron Capture Therapy (BNCT) / 腫瘍集積性化合物 / p-ボロノフェニルアラニン チロシン ジペプチド / ρ-ボロノフェニルアラニンチロシンジペプチド / ρ-ボロノフェニルアラニン / 11B-NMR / 中性子補足法(BNCT) / 迅速定量 / 生体試料 / 微量ホウ素 / アルカリ溶融 … More
Except Principal Investigator
悪性黒色腫 / 熱中性子捕捉療法 / BPA / Neutron Capture Therapy / Melanoma / 抗ガングリオシド抗体 / シクロデキストリン / 単クローン抗体 / melanin monomer complex / isoform of MITF / electroporation / transferrin-conjugate gene vector / malignant melanoma / in vivo gene-transfer / cancer boron neutron capture therapy / 遺伝子導入 / キトサンナノパーティクル / BPAメラニンモノマー錯体 / MITFアイソフォーム / エレクトロポレーション / トランスフェリン複合体ベクター / in vivo遺伝子導入 / がん熱中性子捕捉療法 / Thermal Neutron Capture Therapy / Epithermal / Linear Accelerator / ^<12>B-BPA / Boron / tyrosinase / RBE / ^<10>B-p-bornophenylalanine / boron-10 / melanoma / epithermal / thermal neutron capture therapy / 熱外中性子 / 線形加速器 / ボロン化合物 / Positron Emission Tomography / Bolus / Malignant Melanoma / 皮膚血管肉腫 / ポジトロンCT / 中性子エネルギーシフタ- / PET / ボーラス / PET diagnosis / 悪性黒子型黒色腫 / 黒色腫 / PET画像診断 / 同位体科学 / イオン交換 / リチウム同位体 / 放射線化学 / 同位体 / 磁気共鳴画像 / 単クロ-ン抗体 / 熱中性子捕促療法 Less
  • Research Projects

    (11 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (21 People)
  •  A New Principle of Isotope Enrichment by Chemical Methods

    • Principal Investigator
      ISHIKAWA Atsushi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Nuclear engineering
    • Research Institution
      Shinshu University
  •  Analysis of Behavior of Boron Compounds for Neutron Capture Therapy in Animal Organism by Nuclear Magnetic ResonancePrincipal Investigator

    • Principal Investigator
      YOSHINO Kazuo
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nuclear engineering
    • Research Institution
      Shinsyu University
  •  Development of tumor-seeking compounds for neutron capture therapy by clarification of the accumulating mechanismPrincipal Investigator

    • Principal Investigator
      YOSHIRO Kazuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nuclear engineering
    • Research Institution
      Shinshu University
  •  Gene Transfer-applied Cancer Boron Neutron Capture Therapy : Expansion of therapeutic applicability

    • Principal Investigator
      MISHIMA Yutaka
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Kobe University
  •  Establishment of Boron Neutron Capture Therapy for Primary and Metastatic Melanoma Using Atomic Reactor and Accelerator

    • Principal Investigator
      ICHIHASHI Masamitsu
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      Kobe University
  •  Further Development of Thermal Neutron Capture Therapy for Metastatic and Deeply-Invasive Human Malignant Melanoma

    • Principal Investigator
      MISHIMA Yutaka
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Kobe University
  •  Establishment of Optimal Thermal Neutron Capture Therapy for 5 Types of Human Malignant Melanoma

    • Principal Investigator
      MISHIMA Yutaka
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Kobe University
  •  ホウ素熱中性子捕捉療法の適応拡大に関する研究 副題:単クロ-ン抗体利用の ^<10>B集積,即発γ線による癌診断,L体単離による ^<10>BーBPAの薬効増強

    • Principal Investigator
      三島 豊
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  アルカリ溶融分解法による生体試料中の微量ホウ素の迅速定量Principal Investigator

    • Principal Investigator
      吉野 和夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      分析・地球化学
    • Research Institution
      Shinshu University
  •  ホウ酸熱中性子補促療法の適応拡大に関する研究 副題:単クローン抗体利用の^<10>B集積,即発γ線による癌診断,L体単離による^<10>BーBPAの薬効増強

    • Principal Investigator
      MISHIMA Yutaka
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  ホウ素熱中性子捕捉療法の適応拡大に関する研究 副題:単クローン抗体利用の^<10>B集積、即発γ線による癌診断、L体単離による^<10>B-BPAの薬効増強

    • Principal Investigator
      三島 豊
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University

All 2013 2012 2011 2003 2002 2001 2000

All Journal Article Presentation Book

  • [Book] 悪性黒色腫の診断・治療指針2001

    • Author(s)
      市橋正光, 福田寛, 吉野和夫, 平塚純一, 古林徹, 荒木敬司, 上田正登, 鶴顕太
    • Total Pages
      196
    • Publisher
      金原出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Book] 平成11年度中性子捕捉療法の現状と課題および今後の展開に関する調査報告書2000

    • Author(s)
      吉野和夫, 切畑光統
    • Total Pages
      294
    • Publisher
      財団法人 医用原子力技術研究振興財団
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] ^<11>B NMR Study of p-Carboxybenzeneboronic Acid Ions for Complex Formation with Some Monosaccharides2003

    • Author(s)
      T.M.Bulbul Islam, K.Yoshino, A.Sasane
    • Journal Title

      Anal.Sci. 19

      Pages: 455-460

    • NAID

      80015831100

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Boron Neutron Capture Therapy (BNCT) for Malignant Melanoma with Special Reference to Absorbed Doses to the Normal Skin and Tumor2003

    • Author(s)
      H.Fukuda, J.Hiratsuka, T.Kobayashi, K.Yoshino, H.Karashima, K.Turu, K.Araki, Y.Mishima, M.Ichihashi
    • Journal Title

      Australas.Phys.Eng.Sci.Med 26(3)

      Pages: 78-84

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Boron Neutron Capture Therapy (BNCT) for Malignant Melanoma with Special Reference to Absorbed Doses to the Normal Skin and Tumor2003

    • Author(s)
      H.Fukuda, J.Hiratsuka, T.Kobayashi, K.Yoshino, H.Karashima, K.Turu, K.Araki, Y.Mishima, M.Ichihashi
    • Journal Title

      Australas.Phys.Eng.Sci.Med. 26(3)

      Pages: 78-84

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] ^<11>B NMR Study of p-Carboxybenzeneboronic Acid Ions for Complex Formation with Some Monosaccharides2003

    • Author(s)
      T.M.Bulbul Islam, K.Yoshino, A.Sasane
    • Journal Title

      Anal Sci. 19

      Pages: 455-460

    • NAID

      80015831100

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Measurement of Optical Purity of p-BPA-Tyrosine Dipeptide2002

    • Author(s)
      N.Sato, K.Yoshino, K.Kitta, Y.Saitake.J.Hiratsuka, M.Ichihashi
    • Journal Title

      Peptide Science 2001 (H.Aoyagi ed)(The Japanese Peptide Society)

      Pages: 245-248

    • NAID

      10009660521

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Measurement of Optical Purity of p-BPA-Tyrosine Dipeptide2002

    • Author(s)
      N.Sato, K.Yoshino, K.Kitta, Y.Saitake, J.Hiratsuka, M.Ichihashi
    • Journal Title

      Peptide Science 2001(H.Aoyagi ed), The Japanese Peptide Society

      Pages: 245-248

    • NAID

      10009660521

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] ^1H and ^<11>B NMR study of p-Toluene Boronic Acid and Anhydride2002

    • Author(s)
      T.M.Bulbul Islam, K.Yoshino, H.Nomura, T.Mizuno, A.Sasane
    • Journal Title

      Anal.Sci. 18

      Pages: 363-366

    • NAID

      10011314417

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Current Clinical Paradigms in Melanoma BNCT, Leading to Cell Modulation Era Teamed with Active ^<10>B-Biodelivery Systems2001

    • Author(s)
      Y.Mishima, H.Kondoh, K.Yoshino, J.Hiratsuka
    • Journal Title

      Frontiers in Neutron Capture Therapy(M.F.Hawthorne et al. eds.)(Kluwer Academic/Plenum Publishers, New York)

      Pages: 1365-1382

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Fluorination of p-Boronophenylalanine2001

    • Author(s)
      K.Yoshino, Y.Inamoto, T.Ido, H.Kakihana, M.Ichihashi, Y.Mishima
    • Journal Title

      Frontiers in Neutron Capture Therapy (M.F.Hawthorne et al.eds.)(Kluwer Academic / Plenum Publishers New York)

      Pages: 831-834

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] A Further Mechanism Study of Boron Accumulation to and Release from Melanoma with p-Boronophenylalanine2001

    • Author(s)
      K.Yoshino, M.Kamijo, M.Kimura, Y.Mishima, H.Kondoh, M.Kadota, S.Ito, K.Wakamatsu, H.Kakihana
    • Journal Title

      Frontiers in Neutron Capture Therapy(M.F.Hawthorne et al. eds.)(Kluwer Academic/Plenum Publishers, New York)

      Pages: 985-989

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Thermal Neutron Capture Therapy2001

    • Author(s)
      M.Ichihashi, H.Fukuda, K.Yoshino, J.Hiratsuka, T.Kobayash K.Araki, M.Ueda, K.Tsuru
    • Journal Title

      Diagnosis, and Medical Treatment Policy for Melanoma (Kanehara Co.Ltd.)

      Pages: 176-182

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Structure Determination of p-Boronophenylalanine-Fructose Complex Using ^1J_<cc> coupling Constants2001

    • Author(s)
      M.Kitazawa, K.Yoshino
    • Journal Title

      Frontiers in Neutron Capture Therapy(M.F.Hawthorne et al. eds.)(Kluwer Academic/Plenum Publishers, New York)

      Pages: 857-861

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Simultaneous Determination of p-Boronophenylalanine and Boric Acid Using ^<11>B-NMR2001

    • Author(s)
      K.Yoshino, Y.Tanaka, H.Kakihana, M.Ichihashi, Y.Mishima
    • Journal Title

      Frontiers in Neutron Capture Therapy (M.F.Hawthorne et al.eds.)(Kluwer Academic / Plenum Publishers New York)

      Pages: 863-868

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Simultaneous Determination of p-Boronophenylalanine and Boric Acid Using ^<11>B-NMR2001

    • Author(s)
      K.Yoshino, Y.Tanaka, H.Kakihana, M.Ichihashi, Y.Mishima
    • Journal Title

      Frontiers in Neutron Capture Therapy(M.F.Hawthorne et al. eds.)(Kluwer Academic/Plenum Publishers, New York)

      Pages: 863-868

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Current Clinical Paradigms in Melanoma BNCT, Leading to Cell Modulation Era Teamed with Active ^<10>B-Biodelivery Systems2001

    • Author(s)
      Y.Mishima, H.Kondoh, K.Yoshino, J.Hiratsuka
    • Journal Title

      Frontiers in Neutron Capture Therapy (M.F.Hawthorne et al.eds.)(Kluwer Academic / Plenum Publishers New York)

      Pages: 1365-1382

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Structure Determination of p-Boronophenylalanine-Fructose Complex Using 1^J_<cc> coupling Constants2001

    • Author(s)
      M.Kitazawa, K.Yoshino
    • Journal Title

      Frontiers in Neutron Capture Therapy (M.F.Hawthorne et al.eds.)(Kluwer Academic / Plenum Publishers New York)

      Pages: 857-861

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Fluorination of p-Boronophenylalanine2001

    • Author(s)
      K.Yoshino, Y.Inamoto, T.Ido, H.Kakihana, M.Ichihashi, Y.Mishima
    • Journal Title

      Frontiers in Neutron Capture Therapy(M.F.Hawthorne et al. eds.)(Kluwer Academic/Plenum Publishers, New York)

      Pages: 831-834

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Biodistribution of Boron Concentration on Melanoma-bearing Hamsters after Administration of p-, m-, o-Boronophenylalanine2000

    • Author(s)
      J.Hiratsuka, K.Yoshino, H.Kondoh, Y.Imajo, Y.Mishima
    • Journal Title

      Jpn.J.Cancer Res. 91

      Pages: 446-450

    • NAID

      10008056797

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] A Further Mechanism Study of Boron Accumulation to and Release from Melanoma with p-Boronophenylalanine New York2000

    • Author(s)
      K.Yoshino, M.Kamijo, M.Kimura, Y.Mishima, H.Kondoh, M.Kadota, S.Ito, K.Wakamatsu, H.Kakihana
    • Journal Title

      Frontiers in Neutron Capture Therapy (M.F.Hawthorne et al.eds.)(Kluwer Academic / Plenum Publishers)

      Pages: 985-989

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Present Situation and Future of the Compounds for Neutron Capture Therapy2000

    • Author(s)
      K.Yoshino, M.Kirihata
    • Journal Title

      Annual Report (1999) for Present Situation with Problems and Development in Future of Neutron Capture Therapy (Association for Nuclear Technology in Medicine)

      Pages: 49-73

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Biodistribution of Boron Concentration on Melanoma-bearing Hamsters after Administration of p-, m-, o-Boronophenylalanine2000

    • Author(s)
      J.Hiratsuka, K.Yoshino, H.Kondoh, Y.Imajo, Y.Mishima
    • Journal Title

      Jpn.J Cancer Res. 91

      Pages: 446-450

    • NAID

      10008056797

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Journal Article] Selective Uptake of para-Boronophenylalanine Increases in Amelanotic Melanoma Cells Transfected by the Tyrosinase Gene2000

    • Author(s)
      J.Hiratsuka, H.Kondoh, T.Tsuboi, K.Yoshino, Y.Imajo, Y.Mishima
    • Journal Title

      Melanoma Research 10

      Pages: 297-302

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12680507
  • [Presentation] 同位体の濃縮と分離に関する新しい方法2013

    • Author(s)
      石川厚, 平井和彦, 千賀達也, 大木寛,成田進, 吉野和夫
    • Organizer
      第61回質量分析総合討論会
    • Place of Presentation
      つくば
    • Year and Date
      2013-09-10
    • Data Source
      KAKENHI-PROJECT-22656211
  • [Presentation] リチウム吸着帯の溶離展開2013

    • Author(s)
      石川厚, 佐々木美絵, 千賀達也, 大木寛,吉野和夫
    • Organizer
      第11回同位体科学会研究発表会
    • Place of Presentation
      東京
    • Year and Date
      2013-03-14
    • Data Source
      KAKENHI-PROJECT-22656211
  • [Presentation] リチウム同位体の溶離2012

    • Author(s)
      石川厚, 平井和彦, 大木寛, 吉野和夫
    • Organizer
      第10回同位体科学会研究発表会
    • Place of Presentation
      東京
    • Year and Date
      2012-03-08
    • Data Source
      KAKENHI-PROJECT-22656211
  • [Presentation] イオン交換法による同位体濃縮の新しい方法2011

    • Author(s)
      石川厚, 平井和彦, 水野直人, 塩沢能好人,大木寛, 吉野和夫
    • Organizer
      第9回同位体科学会研究発表会
    • Place of Presentation
      東京, 東日本大震災による計画停電等により研究発表会中止, 要旨のみ発表.
    • Year and Date
      2011-03-16
    • Data Source
      KAKENHI-PROJECT-22656211
  • 1.  MISHIMA Yutaka (10073743)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  FUKUDA Hiroshi (30125645)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  HIRATSUKA Junichi (30192298)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 11 results
  • 4.  ICHIHASHI Masamitsu (00030867)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  KOBAYASHI Tooru (90089136)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  神田 啓治 (10027419)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  奥村 勝彦 (60025707)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  徳久 剛史 (20134364)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  ISHIKAWA Atsushi (40242713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 10.  OHKI Hiroshi (60241783)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 11.  UTSUMI Hiroshi (20025646)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  FUKUMORI Yoshinobu (60102927)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ONO Koji (90122407)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SHIBAHARA Shigeki (70206142)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TAMAKI Norihiko (10030941)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  井戸 達雄 (80134063)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  玉置 憲一 (50055860)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  成田 進 (10208085)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  谷山 絋太郎 (70030898)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  新津 洋司郎 (10045502)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SASAKI Makoto
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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