YOSHINO Kazuo 吉野和夫

Researcher Number	70143964
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2010 – 2012: 信州大学, 理学部, 教授 2003: Shinsyu University, Department of Chemistry, Assoc.Prof., 理学部, 助教授 1996 – 2003: 信州大学, 理学部, 助教授 1988 – 1994: 信州大学, 理学部, 助手
Review Section/Research Field	Principal Investigator Nuclear engineering / 分析・地球化学 Except Principal Investigator Dermatology / Nuclear engineering
Keywords	Principal Investigator ^<11>B-NMR / DHICA / DHI / 悪性黒色腫 / p-ボロノフェニルアラニン / 中性子捕捉療法(BNCT) / メラニン / 悪性黒色腫(メラノーマ) / 中性子捕捉療法 / Melanin Precursor … More / Melanin / Boron Neutron Capture Therapy / Melanoma / p-BPA / 5-S-システニルドーパ / メラニンモノマー / フェオメラニン / ユウメラニン / m-ボロノフェニルアラニン / 中性子補足療法(NCT) / エピネフリン / ノルエピネフリン / ドーパミン / 中性子捕捉療法(NCT) / メラニン前駆体 / p-ボロノフェニルアラニン(p-BPA) / p-Boronophenylalanine-tyrosine dipeptide / melanin / p-Boronophenylalanine / melanoma / ィイD111ィエD1B-NMR / Boron Neutron Capture Therapy (BNCT) / 腫瘍集積性化合物 / p-ボロノフェニルアラニンチロシンジペプチド / ρ-ボロノフェニルアラニンチロシンジペプチド / ρ-ボロノフェニルアラニン / 11B-NMR / 中性子補足法(BNCT) / 迅速定量 / 生体試料 / 微量ホウ素 / アルカリ溶融 … More Except Principal Investigator 悪性黒色腫 / 熱中性子捕捉療法 / BPA / Neutron Capture Therapy / Melanoma / 抗ガングリオシド抗体 / シクロデキストリン / 単クローン抗体 / melanin monomer complex / isoform of MITF / electroporation / transferrin-conjugate gene vector / malignant melanoma / in vivo gene-transfer / cancer boron neutron capture therapy / 遺伝子導入 / キトサンナノパーティクル / BPAメラニンモノマー錯体 / MITFアイソフォーム / エレクトロポレーション / トランスフェリン複合体ベクター / in vivo遺伝子導入 / がん熱中性子捕捉療法 / Thermal Neutron Capture Therapy / Epithermal / Linear Accelerator / ^<12>B-BPA / Boron / tyrosinase / RBE / ^<10>B-p-bornophenylalanine / boron-10 / melanoma / epithermal / thermal neutron capture therapy / 熱外中性子 / 線形加速器 / ボロン化合物 / Positron Emission Tomography / Bolus / Malignant Melanoma / 皮膚血管肉腫 / ポジトロンCT / 中性子エネルギーシフタ- / PET / ボーラス / PET diagnosis / 悪性黒子型黒色腫 / 黒色腫 / PET画像診断 / 同位体科学 / イオン交換 / リチウム同位体 / 放射線化学 / 同位体 / 磁気共鳴画像 / 単クロ-ン抗体 / 熱中性子捕促療法 Less

A New Principle of Isotope Enrichment by Chemical Methods
- Principal Investigator
  
  ISHIKAWA Atsushi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nuclear engineering
- Research Institution
  Shinshu University
Analysis of Behavior of Boron Compounds for Neutron Capture Therapy in Animal Organism by Nuclear Magnetic ResonancePrincipal Investigator
- Principal Investigator
  
  YOSHINO Kazuo
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nuclear engineering
- Research Institution
  Shinsyu University
Development of tumor-seeking compounds for neutron capture therapy by clarification of the accumulating mechanismPrincipal Investigator
- Principal Investigator
  
  YOSHIRO Kazuo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nuclear engineering
- Research Institution
  Shinshu University
Gene Transfer-applied Cancer Boron Neutron Capture Therapy : Expansion of therapeutic applicability
- Principal Investigator
  
  MISHIMA Yutaka
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Kobe University
Establishment of Boron Neutron Capture Therapy for Primary and Metastatic Melanoma Using Atomic Reactor and Accelerator
- Principal Investigator
  
  ICHIHASHI Masamitsu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Dermatology
- Research Institution
  Kobe University
Further Development of Thermal Neutron Capture Therapy for Metastatic and Deeply-Invasive Human Malignant Melanoma
- Principal Investigator
  
  MISHIMA Yutaka
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Kobe University
Establishment of Optimal Thermal Neutron Capture Therapy for 5 Types of Human Malignant Melanoma
- Principal Investigator
  
  MISHIMA Yutaka
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Kobe University
ホウ素熱中性子捕捉療法の適応拡大に関する研究副題:単クロ-ン抗体利用の ^<10>B集積,即発γ線による癌診断,L体単離による ^<10>BーBPAの薬効増強
- Principal Investigator
  
  三島豊
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kobe University
アルカリ溶融分解法による生体試料中の微量ホウ素の迅速定量Principal Investigator
- Principal Investigator
  
  吉野和夫
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分析・地球化学
- Research Institution
  Shinshu University
ホウ酸熱中性子補促療法の適応拡大に関する研究副題:単クローン抗体利用の^<10>B集積,即発γ線による癌診断,L体単離による^<10>BーBPAの薬効増強
- Principal Investigator
  
  MISHIMA Yutaka
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kobe University
ホウ素熱中性子捕捉療法の適応拡大に関する研究副題:単クローン抗体利用の^<10>B集積、即発γ線による癌診断、L体単離による^<10>B-BPAの薬効増強
- Principal Investigator
  
  三島豊
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kobe University

All 2013 2012 2011 2003 2002 2001 2000

All Journal Article Presentation Book

[Book] 悪性黒色腫の診断・治療指針2001
- Author(s)
  市橋正光, 福田寛, 吉野和夫, 平塚純一, 古林徹, 荒木敬司, 上田正登, 鶴顕太
- Total Pages
  196
- Publisher
  金原出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Book] 平成11年度中性子捕捉療法の現状と課題および今後の展開に関する調査報告書2000
- Author(s)
  吉野和夫, 切畑光統
- Total Pages
  294
- Publisher
  財団法人医用原子力技術研究振興財団
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] ^<11>B NMR Study of p-Carboxybenzeneboronic Acid Ions for Complex Formation with Some Monosaccharides2003
- Author(s)
  T.M.Bulbul Islam, K.Yoshino, A.Sasane
- Journal Title
  
  Anal.Sci. 19
  
  Pages: 455-460
- NAID
  80015831100
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Boron Neutron Capture Therapy (BNCT) for Malignant Melanoma with Special Reference to Absorbed Doses to the Normal Skin and Tumor2003
- Author(s)
  H.Fukuda, J.Hiratsuka, T.Kobayashi, K.Yoshino, H.Karashima, K.Turu, K.Araki, Y.Mishima, M.Ichihashi
- Journal Title
  
  Australas.Phys.Eng.Sci.Med 26(3)
  
  Pages: 78-84
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Boron Neutron Capture Therapy (BNCT) for Malignant Melanoma with Special Reference to Absorbed Doses to the Normal Skin and Tumor2003
- Author(s)
  H.Fukuda, J.Hiratsuka, T.Kobayashi, K.Yoshino, H.Karashima, K.Turu, K.Araki, Y.Mishima, M.Ichihashi
- Journal Title
  
  Australas.Phys.Eng.Sci.Med. 26(3)
  
  Pages: 78-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] ^<11>B NMR Study of p-Carboxybenzeneboronic Acid Ions for Complex Formation with Some Monosaccharides2003
- Author(s)
  T.M.Bulbul Islam, K.Yoshino, A.Sasane
- Journal Title
  
  Anal Sci. 19
  
  Pages: 455-460
- NAID
  80015831100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Measurement of Optical Purity of p-BPA-Tyrosine Dipeptide2002
- Author(s)
  N.Sato, K.Yoshino, K.Kitta, Y.Saitake.J.Hiratsuka, M.Ichihashi
- Journal Title
  
  Peptide Science 2001 (H.Aoyagi ed)(The Japanese Peptide Society)
  
  Pages: 245-248
- NAID
  10009660521
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Measurement of Optical Purity of p-BPA-Tyrosine Dipeptide2002
- Author(s)
  N.Sato, K.Yoshino, K.Kitta, Y.Saitake, J.Hiratsuka, M.Ichihashi
- Journal Title
  
  Peptide Science 2001(H.Aoyagi ed), The Japanese Peptide Society
  
  Pages: 245-248
- NAID
  10009660521
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] ^1H and ^<11>B NMR study of p-Toluene Boronic Acid and Anhydride2002
- Author(s)
  T.M.Bulbul Islam, K.Yoshino, H.Nomura, T.Mizuno, A.Sasane
- Journal Title
  
  Anal.Sci. 18
  
  Pages: 363-366
- NAID
  10011314417
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Current Clinical Paradigms in Melanoma BNCT, Leading to Cell Modulation Era Teamed with Active ^<10>B-Biodelivery Systems2001
- Author(s)
  Y.Mishima, H.Kondoh, K.Yoshino, J.Hiratsuka
- Journal Title
  
  Frontiers in Neutron Capture Therapy(M.F.Hawthorne et al. eds.)(Kluwer Academic/Plenum Publishers, New York)
  
  Pages: 1365-1382
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Fluorination of p-Boronophenylalanine2001
- Author(s)
  K.Yoshino, Y.Inamoto, T.Ido, H.Kakihana, M.Ichihashi, Y.Mishima
- Journal Title
  
  Frontiers in Neutron Capture Therapy (M.F.Hawthorne et al.eds.)(Kluwer Academic / Plenum Publishers New York)
  
  Pages: 831-834
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] A Further Mechanism Study of Boron Accumulation to and Release from Melanoma with p-Boronophenylalanine2001
- Author(s)
  K.Yoshino, M.Kamijo, M.Kimura, Y.Mishima, H.Kondoh, M.Kadota, S.Ito, K.Wakamatsu, H.Kakihana
- Journal Title
  
  Frontiers in Neutron Capture Therapy(M.F.Hawthorne et al. eds.)(Kluwer Academic/Plenum Publishers, New York)
  
  Pages: 985-989
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Thermal Neutron Capture Therapy2001
- Author(s)
  M.Ichihashi, H.Fukuda, K.Yoshino, J.Hiratsuka, T.Kobayash K.Araki, M.Ueda, K.Tsuru
- Journal Title
  
  Diagnosis, and Medical Treatment Policy for Melanoma (Kanehara Co.Ltd.)
  
  Pages: 176-182
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Structure Determination of p-Boronophenylalanine-Fructose Complex Using ^1J_<cc> coupling Constants2001
- Author(s)
  M.Kitazawa, K.Yoshino
- Journal Title
  
  Frontiers in Neutron Capture Therapy(M.F.Hawthorne et al. eds.)(Kluwer Academic/Plenum Publishers, New York)
  
  Pages: 857-861
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Simultaneous Determination of p-Boronophenylalanine and Boric Acid Using ^<11>B-NMR2001
- Author(s)
  K.Yoshino, Y.Tanaka, H.Kakihana, M.Ichihashi, Y.Mishima
- Journal Title
  
  Frontiers in Neutron Capture Therapy (M.F.Hawthorne et al.eds.)(Kluwer Academic / Plenum Publishers New York)
  
  Pages: 863-868
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Simultaneous Determination of p-Boronophenylalanine and Boric Acid Using ^<11>B-NMR2001
- Author(s)
  K.Yoshino, Y.Tanaka, H.Kakihana, M.Ichihashi, Y.Mishima
- Journal Title
  
  Frontiers in Neutron Capture Therapy(M.F.Hawthorne et al. eds.)(Kluwer Academic/Plenum Publishers, New York)
  
  Pages: 863-868
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Current Clinical Paradigms in Melanoma BNCT, Leading to Cell Modulation Era Teamed with Active ^<10>B-Biodelivery Systems2001
- Author(s)
  Y.Mishima, H.Kondoh, K.Yoshino, J.Hiratsuka
- Journal Title
  
  Frontiers in Neutron Capture Therapy (M.F.Hawthorne et al.eds.)(Kluwer Academic / Plenum Publishers New York)
  
  Pages: 1365-1382
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Structure Determination of p-Boronophenylalanine-Fructose Complex Using 1^J_<cc> coupling Constants2001
- Author(s)
  M.Kitazawa, K.Yoshino
- Journal Title
  
  Frontiers in Neutron Capture Therapy (M.F.Hawthorne et al.eds.)(Kluwer Academic / Plenum Publishers New York)
  
  Pages: 857-861
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Fluorination of p-Boronophenylalanine2001
- Author(s)
  K.Yoshino, Y.Inamoto, T.Ido, H.Kakihana, M.Ichihashi, Y.Mishima
- Journal Title
  
  Frontiers in Neutron Capture Therapy(M.F.Hawthorne et al. eds.)(Kluwer Academic/Plenum Publishers, New York)
  
  Pages: 831-834
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Biodistribution of Boron Concentration on Melanoma-bearing Hamsters after Administration of p-, m-, o-Boronophenylalanine2000
- Author(s)
  J.Hiratsuka, K.Yoshino, H.Kondoh, Y.Imajo, Y.Mishima
- Journal Title
  
  Jpn.J.Cancer Res. 91
  
  Pages: 446-450
- NAID
  10008056797
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] A Further Mechanism Study of Boron Accumulation to and Release from Melanoma with p-Boronophenylalanine New York2000
- Author(s)
  K.Yoshino, M.Kamijo, M.Kimura, Y.Mishima, H.Kondoh, M.Kadota, S.Ito, K.Wakamatsu, H.Kakihana
- Journal Title
  
  Frontiers in Neutron Capture Therapy (M.F.Hawthorne et al.eds.)(Kluwer Academic / Plenum Publishers)
  
  Pages: 985-989
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Present Situation and Future of the Compounds for Neutron Capture Therapy2000
- Author(s)
  K.Yoshino, M.Kirihata
- Journal Title
  
  Annual Report (1999) for Present Situation with Problems and Development in Future of Neutron Capture Therapy (Association for Nuclear Technology in Medicine)
  
  Pages: 49-73
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Biodistribution of Boron Concentration on Melanoma-bearing Hamsters after Administration of p-, m-, o-Boronophenylalanine2000
- Author(s)
  J.Hiratsuka, K.Yoshino, H.Kondoh, Y.Imajo, Y.Mishima
- Journal Title
  
  Jpn.J Cancer Res. 91
  
  Pages: 446-450
- NAID
  10008056797
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Journal Article] Selective Uptake of para-Boronophenylalanine Increases in Amelanotic Melanoma Cells Transfected by the Tyrosinase Gene2000
- Author(s)
  J.Hiratsuka, H.Kondoh, T.Tsuboi, K.Yoshino, Y.Imajo, Y.Mishima
- Journal Title
  
  Melanoma Research 10
  
  Pages: 297-302
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680507
[Presentation] 同位体の濃縮と分離に関する新しい方法2013
- Author(s)
  石川厚, 平井和彦, 千賀達也, 大木寛,成田進, 吉野和夫
- Organizer
  第61回質量分析総合討論会
- Place of Presentation
  つくば
- Year and Date
  2013-09-10
- Data Source
  KAKENHI-PROJECT-22656211
[Presentation] リチウム吸着帯の溶離展開2013
- Author(s)
  石川厚, 佐々木美絵, 千賀達也, 大木寛,吉野和夫
- Organizer
  第11回同位体科学会研究発表会
- Place of Presentation
  東京
- Year and Date
  2013-03-14
- Data Source
  KAKENHI-PROJECT-22656211
[Presentation] リチウム同位体の溶離2012
- Author(s)
  石川厚, 平井和彦, 大木寛, 吉野和夫
- Organizer
  第10回同位体科学会研究発表会
- Place of Presentation
  東京
- Year and Date
  2012-03-08
- Data Source
  KAKENHI-PROJECT-22656211
[Presentation] イオン交換法による同位体濃縮の新しい方法2011
- Author(s)
  石川厚, 平井和彦, 水野直人, 塩沢能好人,大木寛, 吉野和夫
- Organizer
  第9回同位体科学会研究発表会
- Place of Presentation
  東京, 東日本大震災による計画停電等により研究発表会中止, 要旨のみ発表.
- Year and Date
  2011-03-16
- Data Source
  KAKENHI-PROJECT-22656211

1. MISHIMA Yutaka (10073743)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. FUKUDA Hiroshi (30125645)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. HIRATSUKA Junichi (30192298)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
4. ICHIHASHI Masamitsu (00030867)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KOBAYASHI Tooru (90089136)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 神田啓治 (10027419)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 奥村勝彦 (60025707)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 徳久剛史 (20134364)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. ISHIKAWA Atsushi (40242713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. OHKI Hiroshi (60241783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. UTSUMI Hiroshi (20025646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. FUKUMORI Yoshinobu (60102927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ONO Koji (90122407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SHIBAHARA Shigeki (70206142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAMAKI Norihiko (10030941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 井戸達雄 (80134063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 玉置憲一 (50055860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 成田進 (10208085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 谷山絋太郎 (70030898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 新津洋司郎 (10045502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SASAKI Makoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YOSHINO Kazuo 吉野 和夫

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Analysis of Behavior of Boron Compounds for Neutron Capture Therapy in Animal Organism by Nuclear Magnetic ResonancePrincipal Investigator

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Development of tumor-seeking compounds for neutron capture therapy by clarification of the accumulating mechanismPrincipal Investigator

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アルカリ溶融分解法による生体試料中の微量ホウ素の迅速定量Principal Investigator

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[Book] 悪性黒色腫の診断・治療指針2001

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[Book] 平成11年度中性子捕捉療法の現状と課題および今後の展開に関する調査報告書2000

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[Journal Article] ^<11>B NMR Study of p-Carboxybenzeneboronic Acid Ions for Complex Formation with Some Monosaccharides2003

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NAID

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[Journal Article] Boron Neutron Capture Therapy (BNCT) for Malignant Melanoma with Special Reference to Absorbed Doses to the Normal Skin and Tumor2003

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YOSHINO Kazuo 吉野和夫