SEKI Toshihito 関寿人

… Alternative Names

TOSHIHITO Seki 関寿人

Less

Researcher Number	70163087
Other IDs
External Links
Affiliation (Current)	2022: 関西医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2010 – 2012: 関西医科大学, 医学部, 教授 2004 – 2005: 関西医科大学, 医学部, 教授 1996 – 2002: 関西医科大学, 医学部, 助教授 1994 – 1995: 関西医科大学, 医学部, 講師
Review Section/Research Field	Except Principal Investigator Gastroenterology / Gastroenterology
Keywords	Except Principal Investigator TGF-β / Smad / 肝細胞癌 / Hepatocellular Carcinoma / インテグリン / Liver fibrosis / Carcinogenesis / TGF-beta / JNK / CDK … More / シグナル伝達 / 肝発がん / 肝線維化 / 肝発癌 / ヒト肝癌細胞 / 癌転移 / 転移抑制 / 合成オリゴペプチド / Integrin / Hepatocellular carcinoma / Cancer Metastasis / Inhibition of metastasis / Synthetic oligopeptide / 末梢型ベンゾジアゼピンリセプター / 肝性脳症 / Peripheral-Type Benzodiazepine Receptor / Hepatic Encephalopathy / 肝癌細胞 / 転移 / hepatocellular carcinoma / integrin / metastasis / TGF-β受容体 / アクチビン / TGF-R Less

Mechanisms of liver carcinogenesis through phospho-Smad by gene-targeted mice
- Principal Investigator
  
  MATSUZAKI Koichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University
TGF-β Signal Transduction via MAPK in Hepatocellular Carcinoma and Therapeutic Application
- Principal Investigator
  
  MATSUZAKI Koichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University
Autocrine TGF-β Signal Transaction and Regulalion in Hepatocellular Carcinoma.
- Principal Investigator
  
  MATSUZAKI Koichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University
Analyses of TGF-β Signal Transduction Mechanisms in Hepatocellular Carcinoma and Applications for its Treatment.
- Principal Investigator
  
  MATSUZAKI Koichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University
Integrins in hepatocellular carcinoma and antimetastatic therapies
- Principal Investigator
  
  NAITOH Yuji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University
Endogenous Ligands for Intracerebral Peripheral-Type Benzodiazepine Receptor in Hepatic Encephalopathy
- Principal Investigator
  
  NAITOH Yuji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University
IDENTIFICATION OF INTEGRINS ON HUMAN HEPATOCELLULAR CARCINOMAS,AND EXPERIMENTAL INHIBITION OF METASTASIS BY SYNTHETIC OLIGOPEPTIDES
- Principal Investigator
  
  NAITOH Yuji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University

All 2010 2005 2004

All Journal Article Presentation

[Journal Article] Expression of pituitary tumor transforming gene 1 (PTTG1)/securin in hepatitis B virus-associated liver diseases: evidence for a hepatitis B virus X protein-mediated inhibition of PTTG1 ubiquitination and degradation.2010
- Author(s)
  Molina-Jimenez F, Benedicto I, Seki T,Okazaki K, Matsuzaki K, et al.
- Journal Title
  
  Hepatology
  
  Volume: 51 Pages: 777-87
- DOI
  10.1002/hep.23468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390153
[Journal Article] TGF-β and PDGF Signal via JNK-dependent Smad2/3 Phosphorylation in Rat Hepatic Stellate Cells after Acute Liver Injury2005
- Author(s)
  Yoshida K, Matsuzaki K, Mori S, Tahashi Y, Yamagata H, Furukawa F, Seki T, Nishizawa M, Fujisawa J, Okazaki K.
- Journal Title
  
  American Journal of Pathology 166
  
  Pages: 1029-1039
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590646
[Journal Article] Acceleration of Smad2 and Smad3 Phosphorylation via c-Jun N-terminal Kinase during Human Colorectal Carcinogenesis2005
- Author(s)
  Yamagata H, Matsuzaki K, Mori S, Yoshida K, Tahashi Y, Furukawa F, Sekimoto G, Watanabe T, Uemura Y, Sakaida N, Yoshioka K, Kamiyama Y, Seki T, Okazaki K.
- Journal Title
  
  Cancer Research 65
  
  Pages: 157-165
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590646
[Journal Article] TGF-β and HGF Transmit the Signals through JNK-Dependent Smad2/3 Phosphorylation at the Linker Regions2004
- Author(s)
  Mori S, Matsuzaki K, Yoshida K, Furukawa F, Tahashi Y, Yamagata H, Seki T, Matsui H., Nishizawa M, Fujisawa J., Okazaki K.
- Journal Title
  
  Oncogene 23
  
  Pages: 7416-7429
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590646
[Presentation] Smad3 phosphoisoform-mediated signaling during colorectal cancer using chronic colitis mice model2010
- Author(s)
  Matsuzaki K., Seki T., Okazaki K.
- Organizer
  61st Annual Meeting, American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, USA
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22390153

1. MATSUZAKI Koichi (70278638)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
2. NAITOH Yuji (30198014)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. NAKAHASHI Yoshitsugu (70247930)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. OKAZAKI Kazuichi (70145126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. MIYAZAKI Hiroaki (30268370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 城知宏 (40257928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SEKI Toshihito 関 寿人

TOSHIHITO Seki 関 寿人

Research Projects

Research Products

Co-Researchers

Mechanisms of liver carcinogenesis through phospho-Smad by gene-targeted mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

TGF-β Signal Transduction via MAPK in Hepatocellular Carcinoma and Therapeutic Application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Autocrine TGF-β Signal Transaction and Regulalion in Hepatocellular Carcinoma.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of TGF-β Signal Transduction Mechanisms in Hepatocellular Carcinoma and Applications for its Treatment.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Integrins in hepatocellular carcinoma and antimetastatic therapies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Endogenous Ligands for Intracerebral Peripheral-Type Benzodiazepine Receptor in Hepatic Encephalopathy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IDENTIFICATION OF INTEGRINS ON HUMAN HEPATOCELLULAR CARCINOMAS,AND EXPERIMENTAL INHIBITION OF METASTASIS BY SYNTHETIC OLIGOPEPTIDES

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression of pituitary tumor transforming gene 1 (PTTG1)/securin in hepatitis B virus-associated liver diseases: evidence for a hepatitis B virus X protein-mediated inhibition of PTTG1 ubiquitination and degradation.2010

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TGF-β and PDGF Signal via JNK-dependent Smad2/3 Phosphorylation in Rat Hepatic Stellate Cells after Acute Liver Injury2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Acceleration of Smad2 and Smad3 Phosphorylation via c-Jun N-terminal Kinase during Human Colorectal Carcinogenesis2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] TGF-β and HGF Transmit the Signals through JNK-Dependent Smad2/3 Phosphorylation at the Linker Regions2004

Author(s)

Journal Title

Description

Data Source

[Presentation] Smad3 phosphoisoform-mediated signaling during colorectal cancer using chronic colitis mice model2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

SEKI Toshihito 関寿人

TOSHIHITO Seki 関寿人