ASAHARA Toshimasa 浅原利正

Researcher Number	70175850
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2005 – 2007: 広島大学, 病院・教授 2004 – 2006: 広島大学, 病院, 教授 2002 – 2003: 広島大学, 大学院・医歯薬学総合研究科, 教授 1999 – 2001: Hiroshima University, Medical Hospital, Professor, 医学部, 教授 1996 – 1998: 広島大学, 医学部, 助教授 … More 1994 – 1995: 広島大学, 医学部, 講師 1991: Hiroshiama Univ. School of Med. /Research Professor, 医学部, 助手 1990: 広島大学, 医学部・外科学第二講座, 助手 1989: 広島大学, 医学部・外科学第二, 助手 1986 – 1989: 広島大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General surgery / General surgery / Digestive surgery Except Principal Investigator General surgery / Digestive surgery / Medical systems / General medical chemistry / Functional biochemistry / Digestive surgery / Thoracic surgery / Medical sociology
Keywords	Principal Investigator 異種移植 / 臓器移植 / 免疫寛容 / 拒絶反応 / 免疫制御 / microchimerism / ABO血液型不適合移植 / B細胞 / イムノトキシン / 抗体性拒絶反応 … More / 血液型不適合 / ABO不適合移植 / ABO-incompatible transplantation / Xenotransplantation / B cells / 内皮細胞 / 肝移植 / NK細胞 / C型肝炎 / 細胞免疫療法 / 生体内肝冷却灌流 / 全肝血流遮断 / 肝阻血 / 再灌流障害 / PGI_2誘導体 / 閉塞性黄疸 / V-Vバイパス / PGI誘導体 / 肝組織ATP / 肝冷却灌流 / 肝保護 / In-situ hypothermic perfusion / Hepatic vascular exclusion / Liver ischemia / Reperfusion injury / PGI2 analogue / Obstructive jaundice / V-V bypass / 生物学的免疫操作 / マイクロキメリズム / 骨髄移入 / 異種臓器移植 / hamster-to-rat肝移植 / ドナー放射線照射 / recipient骨髄細胞門脈投与 / xenogeneic transplantation / biological modulation / bone marrow augmentation / 移植 / 免疫抑制 / 血液型A、B抗原 / Gal抗原 / 抗体 / Organ Transplantation / Tolerance / Immuno-toxin / Rejection / Immunotoxin / 移植免疫 / NKT細胞 / 抗体拒絶反応 / Transplant immunology / ABO-blood group incompatible transplantation Xenot / Antibody mediated rejection / NKT cell / CD1d … More Except Principal Investigator Axin / APC / β-catenin / Idax / Duplin / Axam / 肝移植 / GSK-3β / 近赤外分光法 / nitric oxide / NM rince / heat shock protein / Dvl / 大腸癌 / strain gauge force transducer / TCF / MCR / Stop codon / URA3 / 5FOA / heparanase / CRC / 虚血 / フリ-ラジカル / ス-パ-オキサイドディスムタ-ゼ / 臓器保存 / NO / CO / 虚血再灌流障害 / 拒絶反応 / デオキシスパーガリン / kupffer細胞 / 脂肪肝 / 近赤外生体分光 / 虚血再潅流障害 / 中性脂肪 / 生体部分肝移植 / 異所性肝移植 / 異所性肝移植部分肝移植 / 同所性部分肝移植 / Partial liver grafting / Auxiliary liver grafting / 肝阻血障害 / TNFα / FK409 / 生体肝移植 / Kupffer cell blockade / nafamostat mesilate / near-infrared spectroscopy / liver ischemia-reperfusion injury / TNF alpha / 細胞増殖 / 消化管運動 / 自律神経温存手術 / Barostat / 機能温存手術 / 一酸化窒素 / 胃受容性弛緩 / 幽門輪温存膵頭十二指腸切除術 / Strain Gauge Force Transducer / gastrointestinal motility / autonomic nerve preserving surgery / barostat / function preserving surgery / nitrogen oxide / gastric adaptive relaxation / pylorus preserving pancreatoduodenectomy / Wntシグナル伝達経路 / β-カテニン / 遺伝子診断 / SUMO化 / 核移行 / リン酸化 / Wnt signaling / genetic diagnosis / 転移性肝癌 / 遺伝子治療 / Wntシグナル / colorectal cancer / metastatic liver cancer / gene therapy / Wnt signaling pathway / 便検査 / 酵母 / stop codon / Stool test / Yeast / 肝臓癌 / 肺転移 / Heparanase / hepatocellular carcinoma / tumor recurrence / ヒト肝細胞 / ヒト組織バンク / 肝細胞バンク / 公的資源化 / 肝細胞 / human hepatosyte / public resource bank / 同所性肝移植 / 肝保存 / 虚血ー血流再開細胞障害 / 抗酸化物質 / フリーラジカル / 肝移植後胆汁流量 / カフ血管吻合 / 脂質過酸化現象 / 肝虚血 / 血流再開細胞障害 / 同時性肝移植 / 虚血一血流再開細胞障害 / カフ血管吻口 / ラット肝移植 / ラット肝移植手技 / ラット移植肝組織酸素飽和度 / ラット移植肝viabilityの判定 / ラット移植肝胆汁流量 / ラット移植肝ATP / ラット移植肝水分含量%; / Orthotopic liver transplantation / Reperfusion injury / Antioxidants / Primary graft failure / Bile secreation / Cuff technique / リンパ球混合培養 / ヒト抑制性T細胞クローン / 非特異的免疫抑制因子 / 抑制性T細胞 / 同種抗原特異的抑制性T細胞 / 抑制性T細胞クローン / サプレッサーT細胞 / サプレッサーT細胞のクローニング / Mixed lymphocyte culture / Human suppressor T cell clone Less

活性化NK細胞移入療法によるC型ウイルス性肝炎の移植後再発防止法の開発Principal Investigator
- Principal Investigator
  
  大段秀樹, 浅原利正
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
Elucidation of the mechanism on carbohydrate antigen recognition by B cells through CD1d mediated signaling and establishment of a method to regulate B cells responding to the carbohydrate antigens in ABO-incompatible transplantation and xePrincipal Investigator
- Principal Investigator
  
  ASAHARA Toshimasa
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
The estab lishmentt of Hiroshima human hepatocyte bank
- Principal Investigator
  
  AMANO Hironobu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical sociology
- Research Institution
  Hiroshima University
近赤外生体分光測定による非侵襲的肝内トリグリセライド定量法の確立
- Principal Investigator
  
  札場保宏
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  Hiroshima University
骨髄由来再生内皮細胞を用いた臓器移植免疫寛容の誘導Principal Investigator
- Principal Investigator
  
  浅原利正
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
Development of novel screening method by detection of APC mutation from colorectal cancer cells in stool
- Principal Investigator
  
  IKEDA Satoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  HIROSHIMA UNIVERSITY
Analysis of the mechanism of cancer invasion and metastasis due to heparanase
- Principal Investigator
  
  MIYATA Yoshihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  HIROSHIMA UNIVERSITY
Development of synthetic immunotoxin that can enable ABC incompatible transplantation and xenotransplantation.Principal Investigator
- Principal Investigator
  
  ASAHARA Toshimasa
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  HIR0SHIMA UNIVERSITY
Development of gene therapy for metastatic liver cancer from colorectal cancer by introduction of Axin gene and TCF decoy using HVJ-E
- Principal Investigator
  
  OKAJIMA Masazumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  HIROSHIMA UNIVERSITY
Strategies for tolerance induction among B cells responding transplantation-associated carbohydrate antigens (with the aim of success in clinical ABO-incompatible transplantation and xenotransplantationPrincipal Investigator
- Principal Investigator
  
  ASAHARA Toshimasa
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
Isolation of novel proteins that regulate the Wnt signaling pathway
- Principal Investigator
  
  KIKUCHI Akira
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  HIROSHIMA UNIVERSITY
肝移植後の各種病態における低分子モノオキシド代謝の解析と制御、治療への応用
- Principal Investigator
  
  DOHI Kiyohiko
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
Regulation of degradation of β-catenin by Axin and application of Axin into gene diagnosis of cancer
- Principal Investigator
  
  KISHIDA Shosei
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General medical chemistry
- Research Institution
  HIROSHIMA UNIVERSITY
The study of the control mechanisms of gastric motility and the change after function preserving operation.
- Principal Investigator
  
  OKAJIMA Masazumi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hiroshima University
Tolerance induction by biological modulation in allogeneic and xenogeneicPrincipal Investigator
- Principal Investigator
  
  ASAHARA Toshimasa
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  HIROSHIMA UNIVERSITY
Studies of non-investigate evaluation and development of therapy for ischemic injury of the liver using new technic of near-infrared specroscopy
- Principal Investigator
  
  DOHI Kiyouhiko
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  HIROSHIMA UNIVERSITY
Experimental study of protective of in-situ hypothermic liver perfusion on the ischemic liver with biliary obstruction in pigsPrincipal Investigator
- Principal Investigator
  
  ASAHARA Toshimasa
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  HIROSHIMA UNIVERSITY
抗酸化剤による虚血肝細胞障害の保護と肝移植への応用
- Principal Investigator
  
  MARUBAYASHI Seiji
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
Study of orthotopic and auxiliary partial liver grafting from living donor
- Principal Investigator
  
  DOHI Kiyohiko
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
Study of Orthotopic Liver Transplantation in Warm Ischemically Damaged Graft-Protective Effects by Antioxidants-
- Principal Investigator
  
  DOHI Kiyohiko
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  HIROSHIMA UNIVERSITY
Study of alloantigen specific human suppressor T cell clone and its clinical application
- Principal Investigator
  
  FUKUDA Yasuhiko
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  HIROSHIMA UNIVERSITY

All 2008 2007 2006 2005

All Journal Article Presentation Book

[Book] 消化器外科学レビュー2007 (分担執筆「9.再生医療」)2007
- Author(s)
  浅原利正
- Publisher
  総合医学社,東京
- Data Source
  KAKENHI-PROJECT-18590493
[Book] 消化器外科学レビュー2007 (分担執筆「9.再生医療」)2007
- Author(s)
  浅原利正
- Publisher
  総合医学社,東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590493
[Book] 消化器外科レビュー2006(「再生医療」分担執筆)2006
- Author(s)
  浅原利正
- Total Pages
  253
- Publisher
  総合医学社
- Data Source
  KAKENHI-PROJECT-18590493
[Journal Article] Rho-associated kinase inhibitor reduces tumor recurrence after liver transplantation in a rat hepatoma model2007
- Author(s)
  T.Ogawa, H.Tashiro, Y.Miyata, Y.Ushitora, Y.Fudaba, T.Kobayashi, K.Arihiro, M.Okajima, T.Asahara
- Journal Title
  
  American Journal of Transplantation 7(2)
  
  Pages: 347-355
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591471
[Journal Article] 2007 Clinicopathologic features of poorly differentiated hepatocellular carcinoma2007
- Author(s)
  K. Oishi, T., Itamoto, H., Amano, S., Fukuda, H., Ohdan, H., Tashiro, F., Shimamoto, T., Asahara
- Journal Title
  
  J Surg. Oncol 95(4)
  
  Pages: 311-316
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590493
[Journal Article] Possible therapeutic effect of lipid supplementation on neurological complications in liver transplant recipients2007
- Author(s)
  Ide, Kentaro, Ohdan, Hideki, Tahara, Hirosyuki, Ishiyama, Kohei, Shishida, Masayuki, Irei, Toshimitsu, Ohira, Masahiro, Tashiro, Hirotaka, Itamoto, Toshiyuki, Asahara, Toshimasa
- Journal Title
  
  Transpl Int 20(7)
  
  Pages: 632-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Journal Article] Role for CD47-SIRPalpha signaling in xenograft rejection by macrojthages2007
- Author(s)
  Ide, Kentaro, Hui, Wang, Tahara, Hiroyuki, Jianxiang, Liu, Xiaoying, Wang, Asahara, Toshimasa, Megan, Sykes, Yong-Guang, Yang, Ohdan, Hideki, Fuchimoto, Yasushi, Egawa, Hiroto, Asahara, Toshimasa
- Journal Title
  
  Proc Natl Acad Sci USA 104(12)
  
  Pages: 5062-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Journal Article] 2007 Repeat hepatectomy for recurrent hepatocellular carcinoma2007
- Author(s)
  T., Itamoto, H., Nakahara, H., Amano, T., Kohashi, H.,Ohdan, H.,Tashiro, T.,Asahara
- Journal Title
  
  Surgery 141
  
  Pages: 589-597
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590493
[Journal Article] The persistent elimination of B cells responding to blood group A carbohydrates by synthetic group A carbohydrates and B-1 cell differentiation blockade : novel concept in preventing antibody-mediated rejection in ABO-incompatible transplantation2007
- Author(s)
  Toshimitsu, Irei, Hideki, Ohdan, Zhou, Wendy, Ishityama, Kohei, Yuka, Tanaka, Ide, Kentaro, Asahara, Toshimasa
- Journal Title
  
  Blood 110(13)
  
  Pages: 4567-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Journal Article] Evidence of immune tolerance to blood group antigens in a case of ABO-incompatible pediatric liver transplantation2007
- Author(s)
  Ohdan, Hideki, Zhou, Wendy, Tanaka, Yuka, Irei, Toshimitsu, Fuchimoto, Yasushi, Egawa, Hiroto, Asahara, Toshimasa
- Journal Title
  
  Am J Transplant 7(9)
  
  Pages: 2190-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Journal Article] Difference in cytotoxicity against hepatocellular carcinoma between liver and periphery natural killer cells in humans.2006
- Author(s)
  Ishiyama K, Asahara T, et al.
- Journal Title
  
  Hepatology 43(2)
  
  Pages: 362-372
- Data Source
  KAKENHI-PROJECT-17659389
[Journal Article] Liver sinusoidal endothelial cells that endocytose allogeneic cells suppress T cells with indirect allospecificity2006
- Author(s)
  Tokita, Daisuke, Shishida, Masayuki, Ohdan, Hideki, Onoe, Takashi, Hara, Hidetaka, Tanaka, Yuka, Ishiyama, Kohei, Mitsuta, Hiroshi, Ide, Kentaro, Arihiro, Koji, Asahara, Toshimasa
- Journal Title
  
  J Immunol 177(6)
  
  Pages: 3615-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Journal Article] Adoptive transfer of TRAIL-expressing natural killer cells prevents recurrence of hepatocellular carcinoma after partial hepatectomy2006
- Author(s)
  Ohira, Masahiro, Ohdan, Hideki, Mitsuta, Hiroshi, Ishiyama, Kohei, Tanaka, Yuka, Igarashi, Yuka, Asahara, Toshimasa
- Journal Title
  
  Transplantation 82(12)
  
  Pages: 1712-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Journal Article] Near-infrared spectroscopic analysis of hemodynamics and mitochondrial redox in right lobe grafts in living-donor liver transplantation.2006
- Author(s)
  Mtsuta H.Ohdan H.Fudaba Y.Irei T.Tashiro H.Itamoto T.Asahara T.
- Journal Title
  
  Am J Transplant 6(4)
  
  Pages: 797-805
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Near-infrared spectroscopic analysis of hemodynamics and mitochondrial redox in right lobe grafts in living-donor liver transplantation2006
- Author(s)
  Mitsuta, Hiroshi, Ohdan, Hideki, Fudaba, Yasuhiro, Irei, Toshimistu, Tashiro, Hirotaka, Itamoto, Toshiyuki, Asahara, Toshimasa
- Journal Title
  
  Am J Transplant 6(4)
  
  Pages: 797-805
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Journal Article] Near-infrared spectroscopic analysis of hemodynamics and mitochondrial redox in right lobe grafts in living-donor liver transplantation.2006
- Author(s)
  Mitsuta H, Asahara T, et al.
- Journal Title
  
  American journal of transplantation 6巻4号
  
  Pages: 797-805
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Difference in cytotoxicity against hepatocellular carcinoma between liver and periphery natural killer cells in humans. Hepatology.2006
- Author(s)
  Iishiyama K, Asahara T, et al.
- Journal Title
  
  Hepatology 43巻2合
  
  Pages: 362-372
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Difference in cytotoxicity against hepatocellular carcinoma between liver and periphery natural killer cells in humans.2006
- Author(s)
  Ishiyama K.Ohdan H.Ohira M.Mitsuta H.Arihiro K.Asahara T.
- Journal Title
  
  Hepatology 42(2)
  
  Pages: 362-372
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Induction of endotoxin tolerance inhibits alloimmune responses2006
- Author(s)
  Ishiyama, Kohei, Ohdan, Hideki, Tokita, Daisuke, Shishida, Masayuki, Tanaka, Yuka, Irei, Toshimitsu, Asahara, Toshimasa
- Journal Title
  
  Transpl Immunol 16(3-4)
  
  Pages: 158-65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Journal Article] Calcineurin inhibitors block B-1 cell differentiation : the relevance to immunosuppressive treatment in ABO incompatible transplantation2005
- Author(s)
  Zhou W, Ohdan H, Asahara T, et al.
- Journal Title
  
  Transplantation Proceedings (in press)
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Antibody- and complement-independent phagocytotic and cytolytic activities of human macrophages toward porcine cells. Xenotransplantation.2005
- Author(s)
  Ide K, Asahara T, et al.
- Journal Title
  
  Xenotransplantation 12巻3号
  
  Pages: 181-188
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Calcineurin inhibitors block B-1 cell differer baton : the relevance to immunosuppressive treatment in ABO-incompatible transplantation.2005
- Author(s)
  Zhou W, Ohdan H, Asahara T.
- Journal Title
  
  Transplant Proc. 37(4)
  
  Pages: 1808-1811
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Antibody- and complement-independent phagocytotic and cytolytic activities of human macrophages toward porcine cells2005
- Author(s)
  Ide K, Ohdan H, Asahara T, et al.
- Journal Title
  
  Xenotransplantation 12
  
  Pages: 181-188
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Calcineurin inhibitors block B-1 cell differentiation : the relevance to immunosuppressive treatment in ABO-incompatible transplantation.2005
- Author(s)
  Zhou W, Asahara T, et al.
- Journal Title
  
  Transplantation proceedings 37巻4号
  
  Pages: 1808-1811
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Antibody- and complement-independent phagocytotic and cytolytic activities of human macrophages toward porcine cells.2005
- Author(s)
  Ide K, Ohdan H, Kobayashi T, Hara H, Ishiya K, Asahara T.
- Journal Title
  
  Xenotrasplantation 12(3)
  
  Pages: 181-188
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Low incidence of acute rejection after living donor liver transplantation : Immunological analyses by MLR using a CFSE labeling technique2005
- Author(s)
  Tanaka Y, Ohdan H, Asahara T, et al.
- Journal Title
  
  Transplantation (in press)
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Low incidence of acute rejection after living-donor liver transplantation : immunologic analyses by mixed lymphocyte reaction using a carboxyfluorescein diacetate succinimidyl ester labeling technique.2005
- Author(s)
  Tanaka Y, Ohdan H, Onoe T, Mitsuta H, Tashiro H, Itamoto T, Asahara T.
- Journal Title
  
  Transplantation 79(9)
  
  Pages: 1262-1267
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390364
[Journal Article] Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice.2005
- Author(s)
  Onoe T, Asahara T, et al.
- Journal Title
  
  The Journal of Immunology 175(1)
  
  Pages: 139-146
- Data Source
  KAKENHI-PROJECT-17659389
[Journal Article] Low incidence of acute rejection after living-donor liver transplantation : immunologic analyses by mixed lymphocyte reaction using a carboxyfluorescein diacetate succinimidyl ester labeling technique.2005
- Author(s)
  Tanaka Y, Asahara T, et al.
- Journal Title
  
  Transplantation 79巻9号
  
  Pages: 1262-1267
- Data Source
  KAKENHI-PROJECT-16390364
[Presentation] Elucidation of the mehcanism of differentiation of B cells responding to blood group antigen and application to ABO-incompatible renal transplantation2008
- Author(s)
  T., Irei, H., Ohdan, Y., Igarashi, K., Ishiyama, Y., Tanaka, K., Ide, M., Shishida, M., Ohira, H., Tahara, M., Bansyodani, Y., Fudaba, F., Shintaku, T., Ishikawa, Y., Fukuda, T., Asahara
- Organizer
  The 41th Annual Meeting of Japan Clinical Renal Transplanataion Society
- Place of Presentation
  Hamamatsu
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Significance of surgical treatment for patients with hepatocelluar carcinoma exceeding milan criteria2008
- Author(s)
  H., Amano, T., Itamoto, Y., Tanimoto, I., Ushitora, H., Ohdan, H., Tashiro, T., Asahara
- Organizer
  8th Word Congress of the International Hepato Pancreato Biliary Assotiation
- Place of Presentation
  Mumbai (INDIA)
- Year and Date
  2008-02-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590493
[Presentation] Treatment of portal vein stenosis after living donor liver transplantation using interventional radiography2008
- Author(s)
  H., Amano, A., Oshita, H., Ohdan, H., Tashiro, T., Asahara, T., Itamoto
- Organizer
  8th Word Congress of the International Hepato Pancreato Hillary Assotiation
- Place of Presentation
  Mumbai (INDIA)
- Year and Date
  2008-02-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590493
[Presentation] Making a tissue donation system in research use of human liver in Hiroshima University2008
- Author(s)
  H., Amano, M., Tanimoto, T., Itamoto, Y., Igarashi, T., Tateno, K., Yoshizaato, T., Asahara
- Organizer
  The 7th Congress Society for Regenerative Medicine
- Place of Presentation
  Nagoya
- Year and Date
  2008-03-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590493
[Presentation] Surgical technic of hepatectomy for hepatocellular carcinoma toward "zero"morbidity2007
- Author(s)
  H., Amano, T., Itamoto, A., Oshita, K., Ishiyama, H., Ohdan, H., Tashiro, T., Asahara
- Organizer
  The 62th Japanese Society Gastroencological Surgery
- Place of Presentation
  Tokyo
- Year and Date
  2007-07-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590493
[Presentation] Human CD47 expression protects porcine cells from xenogeneic human macrophage phagocytosis through inhibitory CD47-SIRPa signaling (Young Investigator Award)2007
- Author(s)
  K., Ide, H., Wang, T., Asahara, M., Sykes, Y.G., Yang, H., Ohdan
- Organizer
  The First Joint International Transpl ant Meeting / The Transplantation Society(TTS) / WTC2006
- Place of Presentation
  Boston, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] B-Cell Tolerance to Blood-Group Antigens Post Pediatric ABO-Incompatible Liver Transplantation2007
- Author(s)
  Y., Igarashi, H., Ohdan, Y., Tanaka, M., Shishida, T., Irei, T., Asahara
- Organizer
  American Transplant Congress 2007
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-05-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Possibility of B cell immunotorelance induction by liver sinusoidal endothelial cells2007
- Author(s)
  Y., Igarashi, H., Ohdan, T., Irei, M., shishida, Y., Tanaka, T., Asahara
- Organizer
  The 43th Annual Meeting of Japan Society for Transplantation
- Place of Presentation
  Sendai
- Year and Date
  2007-11-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Application of Immunosuppressive strategy for ABO-incompatible renal transplantation based on the B cell developmental theory responding to blood group carbohydrates.2007
- Author(s)
  T., Irei, H., Ohdan, Y., Igarashi, K., Ishiyama, Y., Tanaka, K., Ide, M., Shishida, M., Ohira, H., Tahara, M., Bansyodani, T., Asahara
- Organizer
  The 40th Annual Meeting of Janan Clinical renal Transplanataion Society
- Place of Presentation
  Kanazawa
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Mechanism of avoidance of xenogeneic rejection by macrophages through intracellular inhibitory CD47-SIRPa signaling2007
- Author(s)
  K., Ide, H., Ohdan, H., Tahara, N., Basnet, K., Ishiyama, Y., Tanaka, M., Shishida, T., Irei, M., Ohira, Y., Igarashi, T., Asahara
- Organizer
  The 10th Meeting of Japanese Xenotransplantaion Society
- Place of Presentation
  Tokyo
- Year and Date
  2007-03-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Immunogenicity of xenogeneic antigen N-glycolylneuraminic acid (NeuGc)2007
- Author(s)
  H., Tahara, H., Ohdan, K., Ide, N., Basnet, K., Ishiyama, M., Shishida, Y., Tanaka, T., Irei, M., Ohira, Y., Igarashi, M., Doskali, H., Takematsu, Y., Kozutsumi, T., Asahara
- Organizer
  The 10th Meeting of Japanese Xenotransplantaion Society
- Place of Presentation
  Tokyo
- Year and Date
  2007-03-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Risk factors of surgical site infection after heptectomy for hepatocellular carcinoma2007
- Author(s)
  H., Amano, R., Man, T., Itamoto, Y., Tanimoto, I., Ushitora, A., Oshita, H., Ohdan, H., Tashiro, T., Asahara
- Organizer
  The 69th Annual Congress of JSA
- Place of Presentation
  Tokyo
- Year and Date
  2007-01-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590493
[Presentation] B cell tolerance to blood-group antigens post pediatric ABO-incompatible liver transplantation2007
- Author(s)
  Y., Igarashi, H., Ohdan, T., Irei, M., Shishida, Y., Tanaka, T., Asahara
- Organizer
  13th Congress of the European Society for Transplantation
- Place of Presentation
  Prague,Czech
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Possibility of B cell immunotorelance induction by liver sinusoidal endothelial cells2007
- Author(s)
  Y., Igarashi, H., Ohdan, T., Irei, T., Asahara
- Organizer
  The l4th Annual Meeting of ABO-incompatible Transplantation Society
- Place of Presentation
  Nagoya
- Year and Date
  2007-08-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Immunogenicity of N-Glycolylneuraminic Acid(NeuGc) in Xenotransplantation2007
- Author(s)
  H., Tahara, H., Ohdan, K., Ide, N.B., Basnet, T., Asahara, H., Takematsu, Y., Kozutsumi
- Organizer
  American Transplant Congress 2007
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-05-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Crucial role of invariant NKT cells in the production of antibodies against blood group carbohydrate epitopes in ABO-incompatible transplantation2007
- Author(s)
  T., Irei, H., Ohdan, T., Asahara
- Organizer
  American Transplant Congress 2007
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-05-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Surgical treatment of cholangiocellular carcinoma2007
- Author(s)
  H., Amami., T., Itamoto, A., Oshita, I., Ushitora, J., Hashizume, H., Momisako, T., Matumoto, H., Ohdan, H., Tashiro, T., Asahara
- Organizer
  The 19th Meeting of Japanese Society of Hepato-Biliary-Pancreatic surgery
- Place of Presentation
  Yokohama
- Year and Date
  2007-06-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590493
[Presentation] Antibody-dependent rejection against xenogeneic antigen N-glycolylneuraminic acid (NeuGc)2007
- Author(s)
  H., Tahara, H., Ohdan, K., Ide, N., Basnet, K., Ishiyama, M., Shishida, Y., Tanaka, T., Irei, M., Ohira, Y., Igarashi, K., Kajitani, M., Banshodani, H., Takematsu, Y., Kozutsumi, T., Asahara
- Organizer
  The 43th Annual Meeting of Japan Society for Transplantation
- Place of Presentation
  Sendai
- Year and Date
  2007-11-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Elucidation of the mehcanism of differentiation of B cells responding to blood group antigen (co-stimulating effect from NKT cells) and application to ABO-incompatible organ transplantation2007
- Author(s)
  T., Irei, H., Ohdan, K., Ishiyama, Y., Tanaka, K., Ide, M., Shishida, M., Ohira, Y., Igarashi, H., Tahara, B., Nabin, T., Asahara
- Organizer
  The 43th Annual Meeting of Japan Society for Transplantation
- Place of Presentation
  Sendai
- Year and Date
  2007-11-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Periopevative pitfall for the safety inpatients undergoing living donor transplantation2007
- Author(s)
  H., Amano, T., Itamoto, A., Ohshita, I., Ushitora, Y., Tanimoto, K., Ishiyama, H., Ohdan, H., Tashiro, T., Asahara
- Organizer
  The 43th Annual Congress of the Japan Society
- Place of Presentation
  Sendai
- Year and Date
  2007-11-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590493
[Presentation] Each cases of ABO-incompatible liver and kidney transplantation using the immunosuppressive regimenl without splenectomy based on the B cell developmental theory responding to blood group carbohydrates2007
- Author(s)
  T., Irei, H., Ohdan, Y., Igarashi, K., Ishiyama, M., Bansyodani, Y., Tanaka, K., Ide, M., Shishida, M., Ohira, H., Tashiro, T., Itamoto, T., Asahara
- Organizer
  The l4th Annual Meeting of ABO-incompatible Transplantation Society
- Place of Presentation
  Nagoya
- Year and Date
  2007-08-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Genetic induction of human CD47 on porcine cells prevents macrophagemediated xenograft rejection through inhibitory signaling to SIRPα2007
- Author(s)
  K., Ide, H., Wang, H., Tahara, T., Asahara, Sykes, M., Yang YG., H., Ohdan
- Organizer
  CTS-IPITA-IXA2007 Joint Conference
- Place of Presentation
  Mineapolice, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] A case of ABO-incompatible liver transplantationby using the immunosuppressive regimenl without splenectomy based on the B cell developmental theory responding to blood group carbohydrates2007
- Author(s)
  T., Irei, H., Ohdan, Y., Igarashi, K., Ishiyama, S., Kuroda, Y., Tanaka, K., Ide, M., Shishida, M., Ohira, H., Tahara, M., Bansyodani, N., Basnet, M., doskari,T., Asahara
- Organizer
  The 25th Annual Meeting of Chugoku Shikoku Clinical Organ Transplantation society
- Place of Presentation
  Shimane
- Year and Date
  2007-08-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Role of antibodies against N-glycolylneuraminic acid (NeuGc) in acute vascular rejection caused by anti-non-Gal antibodies2007
- Author(s)
  H., Tahara, H., Ohdan, K., Ide, Basnet, NB., H., Takematsu, Y., Kozutsumi, T., Asahara
- Organizer
  CTS-IPITA-IXA2007 Joint Conference
- Place of Presentation
  Mineapolice, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Therapeutic strategy for ABO-incompatible liver transplantation based on the B cell developmental theory responding to blood group carbohydrates2007
- Author(s)
  T., Irei, H., Ohdan, K., Ishiyama, Y., Tanaka, K., Ide, M., Shishida, M., Ohira, Y., Igarashi, H., Tahara, B., Nabin, M., Doskari, T., Asahara
- Organizer
  The 25th annual meeting of Japanese Liver Transplantaion Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] responding to blood group A carbohydrates by using The persistent elimination of B cells GalNAca1-3Fuca1-2Gal oligosaccharides and B-1 cell differentiation blockade (Young Investigator Award)2007
- Author(s)
  T., Irei, W., Zhou, T., Asahara, H., Ohdan
- Organizer
  The First Joint International Transpl ant Meeting / The Transplantation Society(TTS) / WTC2006
- Place of Presentation
  Boston, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] Avoidance of xenogeneic rejection by macrophages through intracellular inhibitory CD47-SIRPa signaling2006
- Author(s)
  K., Ide, H., Ohdan, H., Tahara, K., Ishiyama, Y., Tanaka, M., Shishida, T., Irei, M., Ohira, T., Asahara
- Organizer
  The 42th Annual Meeting of Japan Society, for Transplantation
- Place of Presentation
  Chiba
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] The elucidation of B cell deveropmental mechanism responding to T cell independent blood group carbohydrates and the establishment of immunosippressive methodology for such Bcells2006
- Author(s)
  T., Irei, H., Ohdan, K., Ishiyama, H., Mitsuta, Y., Tanaka, K., Ide, M., Shishida, M., Ohira, T., Asahara
- Organizer
  The 42th Annual Meeting of Japan Society, for Transplantation
- Place of Presentation
  Chiba
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349
[Presentation] The new methodology of the persistent elimination of B cells responding to blood group carbohydrates using the immunotoxin and the possibility of application to ABO incompatible organ transplantation2006
- Author(s)
  T., Irei, H., Ohdan, W., Zhou, K., Ishiyama, Y., Tanaka, K., Ide, M., Shishida, M., Ohira, Y., igarashi, H., Tahara, T., Asahara
- Organizer
  The l3th Annual Meeting of ABO-incompatible Transplantation Society
- Place of Presentation
  Nagoya
- Year and Date
  2006-08-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390349

1. OHDAN Hideki (10363061)

# of Collaborated Projects: 6 results

# of Collaborated Products: 38 results
2. DOHI Kiyohiko (90034024)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. FUKUDA Yasuhiko (40093801)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. MARUBAYASHI Seiji (80144814)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KIKUCHI Akira (10204827)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. OKAJIMA Masazumi (90274068)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. KISHIDA Shosei (50274064)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 札場保宏 (50397981)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SUGINO Keizo (80162882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAHATA Hiroshi (10191181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KISHIDA Michiko (40274089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YOSHIOKA Shinkichiro (30284194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. IKEDA Satoshi (60397924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MIYATA Yoshihiro (50397965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. AMANO Hironobu (30423370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
16. ITAMOTO Toshiyuki (50294575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
17. 田代裕尊 (90359894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 伊禮俊充 (20397946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NAKATA Motomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. AKAHANE Koichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ASAHARA Toshimasa 浅原 利正

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活性化NK細胞移入療法によるC型ウイルス性肝炎の移植後再発防止法の開発Principal Investigator

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Elucidation of the mechanism on carbohydrate antigen recognition by B cells through CD1d mediated signaling and establishment of a method to regulate B cells responding to the carbohydrate antigens in ABO-incompatible transplantation and xePrincipal Investigator

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骨髄由来再生内皮細胞を用いた臓器移植免疫寛容の誘導Principal Investigator

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Development of synthetic immunotoxin that can enable ABC incompatible transplantation and xenotransplantation.Principal Investigator

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Strategies for tolerance induction among B cells responding transplantation-associated carbohydrate antigens (with the aim of success in clinical ABO-incompatible transplantation and xenotransplantationPrincipal Investigator

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Tolerance induction by biological modulation in allogeneic and xenogeneicPrincipal Investigator

ASAHARA Toshimasa 浅原利正