KIKUCHI Toshihiko 菊地俊彦

… Alternative Names

KIKUCHI Tishihiko 菊地俊彦

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Researcher Number	70177799
External Links
Affiliation (based on the past Project Information) *help	2006: 東北大学, 医学系研究科, 助教授 2003 – 2005: Tohoku University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授 2002: Tohoku University Hospital, Assistant Professor, 医学部附属病院, 講師 1999 – 2001: Department of Otolaryngology, Nagasaki University Hospital, Assistant Professor, 医学部・附属病院, 講師 1998: 東北大学, 医学部, 助手 … More 1990: Tohoku Univ. School of Med., Associate, 医学部, 助手 1990: 東北大学, 医学部附属病院, 助手 1989: 東北大学, 医学部・附属病院, 助手 1988: 東北大学, 医学部附属病院, 助手 1987: 東北大学, 医学部・付属病院・耳鼻咽喉科, 助手 Less
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Otorhinolaryngology Except Principal Investigator Otorhinolaryngology / Otorhinolaryngology
Keywords	Principal Investigator gap junction / connexin 26 / inner ear / voltage-gated potassium channel / endocochlear potential / 内リンパ電位 / connexin / Kir4.1 / 免疫組織化学 / 内耳 … More / 遺伝性難聴 / connexin 31 / Na,K-ATPase / Na-K-Cl cotransporter / endolymphatic potential / Brain-4 / nonsyndromic deafness / Kv3.1b / aquaporin / Kv3.4 / GLAST / glutamine synthetase / cochlea / aging / inbred strains / DBA / 2J mouse / C57BL / 6J mouse / CBA / J mouse / 老人性難聴 / connexin26 / voltage-gated protassium channel / kv3.4 / non-syndromic deafness / gas junction / hereditary deafness / pottassium ion / sodium channel / Navl.6 / potassium ion / spiral ganglion cell / herediatary deafness / endocochlear / 蝸牛 / 難聴 / 内リンパ直流電位 / カリウム循環 / Kチャネル / 前庭 / 前庭移行細胞 / kir / 内耳内カリウムイオン循環 / deafness / potassium ion recycle / potassium channel … More Except Principal Investigator 内耳 / 耳管開放症 / 耳管 / Brain-4 / 遺伝性難聴 / 聴力保存 / 電気生理学的研究 / 内耳道 / 聴神経腫瘍 / 中頭蓋窩法 / 側頭骨 / 解剖 / 脂肪細胞 / オストマン脂肪体 / 間葉系幹細胞 / 再生医療 / ノックアウトマウス / コネキシン26 / 内リンパ静止電位 / 老化 / DNA異常 / 老人性難聴 / ミトコンドリアDNA / 老化マウス / 変異 / Brn4 / 加齢 / knockout mice / Connexin-26 / Endocochlear potential / Hereditary deafness / Aging / DNA mutation / 迷路瘻孔 / レーザー / 耳管ピン / 真珠腫 / 中耳真珠腫 / Labyrinthine fistulae / Laser / ET plug / Patulous eustachian tube / Cholesteatoma / 低音障害型感音難聴 / WFSI遺伝子 / 連鎖解析 / 位置的候補遺伝子解析 / 低温障害型感音難聴 / WFS1遺伝子 / 低音障害型難聴 / 遺伝子 / genotype analysis / hereditary hearing loss / low frequency sensorineural hearing loss / WFS1 gene / linkage analysis / positional candidate gene approach / 音響外傷 / 熱ストレス / 有毛細胞 / acoustic trauma / heat stress / hair cell / 超高圧電子顕微鏡 / モルモット / 蝸牛 / 外有毛細胞 / 内有毛細胞 / 求心性神経終末 / 遠心性神経終末 / High-voltage electron microscope / Guinea pig / Cochlea / Outer hair cell / Inner hair cell / Afferent nerve terminal / Efferent nerve terminal / 〓出性中耳炎 / 治療法 / 成因解析 / 滲出性中耳炎 / 病期分類 / 難治化因子 / ケミカルミディエ-タ- / 補体 / 難治例鼓膜病理 / 中耳粘膜病理 / 柴苓湯 / サ-ファクテン局所療法 / ケミカルメディエーター / 鼓膜病理 / コラーゲン線維 / サーファクタント / Secretory otitis media / middle ear effusion / risk factors for SOM / VT insertion / medical managements Less

内耳におけるイオン輸送関連遺伝子の分子生物学的解析と難聴病態の解明Principal Investigator
- Principal Investigator
  
  菊地俊彦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tohoku University
The Stiffness Change of Conditioning Effect in Inner Hair Cells
- Principal Investigator
  
  YOSHIDA Naohiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tohoku University
耳管粘膜下における脂肪細胞の分化誘導-耳管開放症の根本的治療法の開発-
- Principal Investigator
  
  小林俊光
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tohoku University
Analysis of the potassium ion recycling mechanism in the cochlea : a challenge for the better understanding of the inner ear dysfunctionPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Toshihiko, 千葉敏彦
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tohoku University
Expression of voltage-gated potassium channels in the inner ear and herediatary deafness : molecular biological analysisPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Toshihiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tohoku University
Identification of causative gene for hereditary low-frequency sensorineural hearing loss
- Principal Investigator
  
  SAKIHAMA Noriyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagasaki University
中頭蓋窩法における内耳道の簡便同定法の開発―外耳道内照明法の研究―
- Principal Investigator
  
  小林俊光
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagasaki University
進行性感音難聴モデル動物における内耳障害の多角的解析Principal Investigator
- Principal Investigator
  
  菊地俊彦
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagasaki University
Analysis of the pathogenesis of the hereditary non syndromic deafness caused by mutations in connection genesPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Toshihiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagasaki University
The New Treatments for the Complications of Middle Ear Cholesteatoma
- Principal Investigator
  
  KOBAYASHI Toshimitsu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagasaki University
Genetics of Presbyacus's and its clinical application
- Principal Investigator
  
  TAKASAKA Tomonori
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  TOHOKU UNIVERSITY
Functional significance of the gap junctions in the ion transport mechanism in the cochlea -molecular biological analysisPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Toshihiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagasaki University
  Tohoku University
内耳手術における聴力保存に関する基礎的研究
- Principal Investigator
  
  KOBAYASHI Toshimitsu
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tohoku University
Pathogenesis and Managements for Chronic Secretory Otitis Media.
- Principal Investigator
  
  TAKASAKA Tomonori
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tohoku University
Serial section reconstruction of the guinea pig outer and inner hair cells as studied with a high-voltage electron microscope.
- Principal Investigator
  
  SHINKAWA Hideichi
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hirosaki University
  Tohoku University

All 2006 2005 Other

All Journal Article Book

[Book] 遺伝性難聴の病態解析(connexin遺伝子異常) 先端医療シリーズ35 耳鼻咽喉科・頭頸部外科学の最新医療2005
- Author(s)
  菊地俊彦, 美野輪治
- Total Pages
  5
- Publisher
  先端医療技術研究所
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591696
[Book] Analysis of the hereditary deafness : connexin genemutations. (Kaga K., Komune S.(eds))(Senntanniryou Series 35 Jibiinnkouka)2005
- Author(s)
  Kikuchi T., Minowa O.
- Publisher
  Sentanniryou gijutu kennkyuujo, Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591696
[Journal Article] Gap Junctions and Cochlear Homeostasis.2006
- Author(s)
  Zhao H.B., Kikuchi T., Ngezahayo A., White T.W.
- Journal Title
  
  J.Membr.Bop. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591696
[Journal Article] Gap junctions and cochlear homeostasis.2006
- Author(s)
  Zhao H.B., Kikuchi T., Ngezahayo A., White T.W.
- Journal Title
  
  J.Membr Biol (in press)
- Data Source
  KAKENHI-PROJECT-16591696
[Journal Article] Gap junctions and cochlear homeostasis.
- Author(s)
  Zhao H.B., Kikuchi T., Ngezahayo A., White T.W.
- Journal Title
  
  J. Membr Biol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591696

1. KOBAYASHI Toshimitsu (80133958)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. KAWASE Tetsuaki (50169728)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TANAKA Fujinobu (00284688)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. YOSHIDA Naohiro (90291260)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. TAKASAKA Tomonori (80004646)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TSUKASAKI Naoki (70274660)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. OSHIMA Takeshi (40241608)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. IKEDA Katsuhisa (70159614)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. WADA Hiroshi (30111264)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. SHINKAWA Hideichi (90125584)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 高村博光 (50281209)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 千葉敏彦 (70280881)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. NAKAO Yoshiaki (40188884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SAKIHAMA Noriyuki (60264230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MATSUMOTO Naomichi (80325638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YOSHIURA Koh-ichiro (00304931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KATORI Yukio (20261620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HOZAWA Koji (20199459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SHIBAHARA Yoshihiro (70142940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. SUZUKI Mamoru (10206534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 橋本省 (20156285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 佐々木豊 (30221279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 志賀清人 (10187338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 堀井明 (40249983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 古川徹 (30282122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 山内大輔 (70361102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 神田幸彦 (20264244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 末武光子 (40183412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 栗原篤 (80192037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 鈴木秀明 (20187751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. YAGINUMA Yuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 八木沼裕司

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KIKUCHI Toshihiko 菊地 俊彦

KIKUCHI Tishihiko 菊地 俊彦

Research Projects

Research Products

Co-Researchers

内耳におけるイオン輸送関連遺伝子の分子生物学的解析と難聴病態の解明Principal Investigator

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Analysis of the potassium ion recycling mechanism in the cochlea : a challenge for the better understanding of the inner ear dysfunctionPrincipal Investigator

Principal Investigator

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Expression of voltage-gated potassium channels in the inner ear and herediatary deafness : molecular biological analysisPrincipal Investigator

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進行性感音難聴モデル動物における内耳障害の多角的解析Principal Investigator

Principal Investigator

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Analysis of the pathogenesis of the hereditary non syndromic deafness caused by mutations in connection genesPrincipal Investigator

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Functional significance of the gap junctions in the ion transport mechanism in the cochlea -molecular biological analysisPrincipal Investigator

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Principal Investigator

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KIKUCHI Toshihiko 菊地俊彦

KIKUCHI Tishihiko 菊地俊彦