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KIKUCHI Toshihiko  菊地 俊彦

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KIKUCHI Tishihiko  菊地 俊彦

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Researcher Number 70177799
External Links
Affiliation (based on the past Project Information) *help 2006: 東北大学, 医学系研究科, 助教授
2003 – 2005: Tohoku University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授
2002: Tohoku University Hospital, Assistant Professor, 医学部附属病院, 講師
1999 – 2001: Department of Otolaryngology, Nagasaki University Hospital, Assistant Professor, 医学部・附属病院, 講師
1998: 東北大学, 医学部, 助手 … More
1990: Tohoku Univ. School of Med., Associate, 医学部, 助手
1990: 東北大学, 医学部附属病院, 助手
1989: 東北大学, 医学部・附属病院, 助手
1988: 東北大学, 医学部附属病院, 助手
1987: 東北大学, 医学部・付属病院・耳鼻咽喉科, 助手 Less
Review Section/Research Field
Principal Investigator
Otorhinolaryngology / Otorhinolaryngology
Except Principal Investigator
Otorhinolaryngology / Otorhinolaryngology
Keywords
Principal Investigator
gap junction / connexin 26 / inner ear / voltage-gated potassium channel / endocochlear potential / 内リンパ電位 / connexin / Kir4.1 / 免疫組織化学 / 内耳 … More / 遺伝性難聴 / connexin 31 / Na,K-ATPase / Na-K-Cl cotransporter / endolymphatic potential / Brain-4 / nonsyndromic deafness / Kv3.1b / aquaporin / Kv3.4 / GLAST / glutamine synthetase / cochlea / aging / inbred strains / DBA / 2J mouse / C57BL / 6J mouse / CBA / J mouse / 老人性難聴 / connexin26 / voltage-gated protassium channel / kv3.4 / non-syndromic deafness / gas junction / hereditary deafness / pottassium ion / sodium channel / Navl.6 / potassium ion / spiral ganglion cell / herediatary deafness / endocochlear / 蝸牛 / 難聴 / 内リンパ直流電位 / カリウム循環 / Kチャネル / 前庭 / 前庭移行細胞 / kir / 内耳内カリウムイオン循環 / deafness / potassium ion recycle / potassium channel … More
Except Principal Investigator
内耳 / 耳管開放症 / 耳管 / Brain-4 / 遺伝性難聴 / 聴力保存 / 電気生理学的研究 / 内耳道 / 聴神経腫瘍 / 中頭蓋窩法 / 側頭骨 / 解剖 / 脂肪細胞 / オストマン脂肪体 / 間葉系幹細胞 / 再生医療 / ノックアウトマウス / コネキシン26 / 内リンパ静止電位 / 老化 / DNA異常 / 老人性難聴 / ミトコンドリアDNA / 老化マウス / 変異 / Brn4 / 加齢 / knockout mice / Connexin-26 / Endocochlear potential / Hereditary deafness / Aging / DNA mutation / 迷路瘻孔 / レーザー / 耳管ピン / 真珠腫 / 中耳真珠腫 / Labyrinthine fistulae / Laser / ET plug / Patulous eustachian tube / Cholesteatoma / 低音障害型感音難聴 / WFSI遺伝子 / 連鎖解析 / 位置的候補遺伝子解析 / 低温障害型感音難聴 / WFS1遺伝子 / 低音障害型難聴 / 遺伝子 / genotype analysis / hereditary hearing loss / low frequency sensorineural hearing loss / WFS1 gene / linkage analysis / positional candidate gene approach / 音響外傷 / 熱ストレス / 有毛細胞 / acoustic trauma / heat stress / hair cell / 超高圧電子顕微鏡 / モルモット / 蝸牛 / 外有毛細胞 / 内有毛細胞 / 求心性神経終末 / 遠心性神経終末 / High-voltage electron microscope / Guinea pig / Cochlea / Outer hair cell / Inner hair cell / Afferent nerve terminal / Efferent nerve terminal / 〓出性中耳炎 / 治療法 / 成因解析 / 滲出性中耳炎 / 病期分類 / 難治化因子 / ケミカルミディエ-タ- / 補体 / 難治例鼓膜病理 / 中耳粘膜病理 / 柴苓湯 / サ-ファクテン局所療法 / ケミカルメディエーター / 鼓膜病理 / コラーゲン線維 / サーファクタント / Secretory otitis media / middle ear effusion / risk factors for SOM / VT insertion / medical managements Less
  • Research Projects

    (15 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (32 People)
  •  内耳におけるイオン輸送関連遺伝子の分子生物学的解析と難聴病態の解明Principal Investigator

    • Principal Investigator
      菊地 俊彦
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  The Stiffness Change of Conditioning Effect in Inner Hair Cells

    • Principal Investigator
      YOSHIDA Naohiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  耳管粘膜下における脂肪細胞の分化誘導-耳管開放症の根本的治療法の開発-

    • Principal Investigator
      小林 俊光
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  Analysis of the potassium ion recycling mechanism in the cochlea : a challenge for the better understanding of the inner ear dysfunctionPrincipal Investigator

    • Principal Investigator
      KIKUCHI Toshihiko, 千葉 敏彦
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  Expression of voltage-gated potassium channels in the inner ear and herediatary deafness : molecular biological analysisPrincipal Investigator

    • Principal Investigator
      KIKUCHI Toshihiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  Identification of causative gene for hereditary low-frequency sensorineural hearing loss

    • Principal Investigator
      SAKIHAMA Noriyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
  •  中頭蓋窩法における内耳道の簡便同定法の開発―外耳道内照明法の研究―

    • Principal Investigator
      小林 俊光
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
  •  進行性感音難聴モデル動物における内耳障害の多角的解析Principal Investigator

    • Principal Investigator
      菊地 俊彦
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
  •  Analysis of the pathogenesis of the hereditary non syndromic deafness caused by mutations in connection genesPrincipal Investigator

    • Principal Investigator
      KIKUCHI Toshihiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
  •  The New Treatments for the Complications of Middle Ear Cholesteatoma

    • Principal Investigator
      KOBAYASHI Toshimitsu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
  •  Genetics of Presbyacus's and its clinical application

    • Principal Investigator
      TAKASAKA Tomonori
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      TOHOKU UNIVERSITY
  •  Functional significance of the gap junctions in the ion transport mechanism in the cochlea -molecular biological analysisPrincipal Investigator

    • Principal Investigator
      KIKUCHI Toshihiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
      Tohoku University
  •  内耳手術における聴力保存に関する基礎的研究

    • Principal Investigator
      KOBAYASHI Toshimitsu
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  Pathogenesis and Managements for Chronic Secretory Otitis Media.

    • Principal Investigator
      TAKASAKA Tomonori
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  Serial section reconstruction of the guinea pig outer and inner hair cells as studied with a high-voltage electron microscope.

    • Principal Investigator
      SHINKAWA Hideichi
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Hirosaki University
      Tohoku University

All 2006 2005 Other

All Journal Article Book

  • [Book] 遺伝性難聴の病態解析(connexin遺伝子異常) 先端医療シリーズ35 耳鼻咽喉科・頭頸部外科学の最新医療2005

    • Author(s)
      菊地俊彦, 美野輪治
    • Total Pages
      5
    • Publisher
      先端医療技術研究所
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591696
  • [Book] Analysis of the hereditary deafness : connexin genemutations. (Kaga K., Komune S.(eds))(Senntanniryou Series 35 Jibiinnkouka)2005

    • Author(s)
      Kikuchi T., Minowa O.
    • Publisher
      Sentanniryou gijutu kennkyuujo, Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591696
  • [Journal Article] Gap Junctions and Cochlear Homeostasis.2006

    • Author(s)
      Zhao H.B., Kikuchi T., Ngezahayo A., White T.W.
    • Journal Title

      J.Membr.Bop. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591696
  • [Journal Article] Gap junctions and cochlear homeostasis.2006

    • Author(s)
      Zhao H.B., Kikuchi T., Ngezahayo A., White T.W.
    • Journal Title

      J.Membr Biol (in press)

    • Data Source
      KAKENHI-PROJECT-16591696
  • [Journal Article] Gap junctions and cochlear homeostasis.

    • Author(s)
      Zhao H.B., Kikuchi T., Ngezahayo A., White T.W.
    • Journal Title

      J. Membr Biol (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591696
  • 1.  KOBAYASHI Toshimitsu (80133958)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  KAWASE Tetsuaki (50169728)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  TANAKA Fujinobu (00284688)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  YOSHIDA Naohiro (90291260)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  TAKASAKA Tomonori (80004646)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  TSUKASAKI Naoki (70274660)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  OSHIMA Takeshi (40241608)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  IKEDA Katsuhisa (70159614)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  WADA Hiroshi (30111264)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  SHINKAWA Hideichi (90125584)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  高村 博光 (50281209)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  千葉 敏彦 (70280881)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  NAKAO Yoshiaki (40188884)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SAKIHAMA Noriyuki (60264230)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MATSUMOTO Naomichi (80325638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YOSHIURA Koh-ichiro (00304931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KATORI Yukio (20261620)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  HOZAWA Koji (20199459)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SHIBAHARA Yoshihiro (70142940)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  SUZUKI Mamoru (10206534)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  橋本 省 (20156285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  佐々木 豊 (30221279)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  志賀 清人 (10187338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  堀井 明 (40249983)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  古川 徹 (30282122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  山内 大輔 (70361102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  神田 幸彦 (20264244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  末武 光子 (40183412)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  栗原 篤 (80192037)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  鈴木 秀明 (20187751)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  YAGINUMA Yuji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  八木沼 裕司
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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