HIDETO Shimpo 新保秀人

… Alternative Names

Researcher Number	70179076
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2017: 三重大学, 医学系研究科, 教授 2012 – 2015: 三重大学, 医学(系)研究科(研究院), 教授 2007 – 2012: 三重大学, 大学院・医学系研究科, 教授 2004: Mie University, Faculty of Medicine, Professor, 医学部, 教授 2002 – 2003: 三重大学, 医学部, 助教授 … More
Review Section/Research Field	Principal Investigator Thoracic surgery / Thoracic surgery Except Principal Investigator Thoracic surgery / Pediatrics / Thoracic surgery / Cardiovascular surgery / General surgery
Keywords	Principal Investigator 肺高血圧 / p38MAPK / テネイシン / 炎症反応の関与 / 細胞外マトリックス / remodeling of pulmonary artery / 肺血管再構築 / 肺血管構築 / 細胞外マトリクス / inflammation / pulmonary hypertension / P38MAPK … More Except Principal Investigator … More

Study of the autologous endothelialized artificial graft which so not need anticoagulant therapy
- Principal Investigator
  
  KONUMA TAKESHI
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Mie University
胎生期静脈化メカニズムを応用した静脈グラフト治療の実験的研究
- Principal Investigator
  
  武藤紹士
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Mie University
Specific inhibition of tenascin-C with Cilostazol attenuates vascular proliferation in monocrotaline-induced pulmonary hypertension in ratsPrincipal Investigator
- Principal Investigator
  
  SHIMPO HIDETO
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Mie University
Erythropoietin attenuates the sequels of ischaemic spinal cord injury with enhanced recruitment of CD34+ cells in mice
- Principal Investigator
  
  HIRANO KOJI
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Mie University
Pharmacological preconditioning of lung with monophosphoryl lipid A: A role of MyD88-independent signaling pathway.
- Principal Investigator
  
  SHIMAMOTO AKIRA
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Mie University
Role of IL-6-Th17/Treg system in the development of experimental pulmonary hypertension
- Principal Investigator
  
  MITANI Yoshihide
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Mie University
Molecular basis of pulmonary hypertension using mice deficient ina causative gene and an oxidant stress-related gene
- Principal Investigator
  
  YOSHIHIDE Mitani
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Mie University
FR167653 diminishes infarct size in a murine model of myocardial ischemia-reperfusion injury.
- Principal Investigator
  
  YADA Isao
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Mie University
Important role of inflammation on drug induced pulmonary hypertensionPrincipal Investigator
- Principal Investigator
  
  SHIMPO Hideto
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Mie University
Adaptation to Nonpulsatile Mechanical Circulation : Should We Pulse in Mechanical Circulation?
- Principal Investigator
  
  YADA Isao
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Department of Thoracic and Cardiovascular Surgery, Mie University School of Medicine
Role of Endothellial Cells in Reperfusion Injury : Studies on Mechanisms and Prohibition of Reperfusion Injury :
- Principal Investigator
  
  YADA Isao, 草川實
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  MIE UNIVERSITY

All 2016 2015 2011 2010 2009 2008 2007 2004

All Journal Article Presentation

[Journal Article] Role of Heat Shock Proteins in Pharmacological Preconditioning for Lung Ischemia Reperfusion Injury2016
- Author(s)
  A. Shimamoto, M. Takao, H. Shimpo
- Journal Title
  
  The Journal of Heart and Lung Transplantation
  
  Volume: 35
- DOI
  10.1016/j.healun.2016.01.515
- Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592087, KAKENHI-PROJECT-16K10676
[Journal Article] Acute effect of sildenafil on hypoxemic patients (excluding those with Eisenmenger syndrome) with incurable congenital heart disease and disturbed pulmonary vasculature in the mid-term follow-up2011
- Author(s)
  Mitani Y, Ohashi H, Takabayashi S, Shimpo H, Komada Y
- Journal Title
  
  Int J Cardiol
  
  Volume: 146(2) Pages: 273-274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591385
[Journal Article] Acute effect of sildenafil on hypoxemic patients (excluding those with Eisenmenger syndrome) with incurable congenital heart disease and disturbed pulmonary vas culature in the mid-term follow-up2011
- Author(s)
  Mitani Y, Ohashi H, Takabayashi S, Shimpo H, Komada Y
- Journal Title
  
  Int J Cardiol
  
  Volume: 146 Pages: 273-274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591385
[Journal Article] Postnatal course of hypoplastic left heart complex and restrictive foramen ovale2010
- Author(s)
  Hosoki K, Mitani Y, Takabayashi S, Shimpo H, Komada Y.
- Journal Title
  
  Pediatr Cardiol 31(2)
  
  Pages: 270-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591385
[Journal Article] Removal of prostaglandin E2 and increased intraoperative blood pressure during modified ultrafiltration in pediatric cardiac surgery.2009
- Author(s)
  Yokoyama K, Takabayashi S, Komada T, Onoda K, Mitani Y, Iwata H, Shimpo H.
- Journal Title
  
  J Thorac Cardiovasc Surg 137
  
  Pages: 730-735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] In Vivo Plaque Composition and Morphology in Coronary Artery Lesions in The Adolescents and Young Adults Long After Kawasaki Disease : A Virtual Histology-Intravascular Ultrasound Study2009
- Author(s)
  Mitani Y, Ohashi H, Sawada H, Ikeyama Y, Hayakawa H, Takabayashi S, Maruyama K, Shimpo H, Komada Y.
- Journal Title
  
  Circulation 119(21)
  
  Pages: 2829-2836
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591385
[Journal Article] Removal of prostaglandin E2 and increased intraoperative blood pressure during modified ultrafiltration in pediatric cardiac surgery2009
- Author(s)
  Yokoyama K, Takabayashi S, Komada T, Onoda K, Mitani Y, Iwata H, Shimpo H.
- Journal Title
  
  J Thorac Cardiovasc Surg 137(3)
  
  Pages: 142-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591385
[Journal Article] In Vivo Plaque Composition and Morphologyin Coronary Artery Lesions in TheAdolescents and Young Adults Long AfterKawasaki Disease2009
- Author(s)
  Mitani Y(1), Ohashi H(2),Maruyama K(7),Shimpo H(8),計9名
- Journal Title
  
  A Virtual Histology-Intravascular Ultrasound StudyCirculation (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Removal of prostaglandin E2 and increasedintraoperative blood pressure duringmodified ultrafiltration in pediatriccardiac surgery2009
- Author(s)
  Yokoyama K(1), Mitani Y(4), Shimpo H (7), 計7名
- Journal Title
  
  J Thorac Cardiovasc Surg 137(3)
  
  Pages: 730-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Fatal pulmonary lymphangiectasia manifesting after repeated surgeries for intractable chylopericardium and chylothorax in a 20-month-old girl.2008
- Author(s)
  Kamada N, Mitani Y, Kihira K, Iwao A, Sinoki T, Ikeyama Y, Sawada H, Deguchi T, Takabayashi S, Shimpo H, Komada Y.
- Journal Title
  
  Circulation 117
  
  Pages: 1894-1896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Atrial natriuretic peptide gene transfection with a novel envelope vector system ameliorates pulmonary hypertension in rats.2008
- Author(s)
  Mitani Y, Maruyama J, Jiang BH, Sawada H, Shimpo H, Imanaka-Yoshida K, Kaneda Y, Komada Y, Maruyama K.
- Journal Title
  
  J Thorac Cardiovasc Surg 136
  
  Pages: 142-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Suture repair of pectus excavatum at thetime of cardiac surgery on an infantAnn Thorac Surg2008
- Author(s)
  Takabayashi S(1), Ohashi H(4), MitaniY(4), Shimpo H(5), 計4名
- Journal Title
  
  Ann Thorac Surg 85(2)
  
  Pages: 651-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Atrial natriuretic peptide genetransfection with a novel envelope vectorsystem ameliorates pulmonary hypertensionin rats2008
- Author(s)
  Mitani Y(1), Shimpo H(5), Maruyama K(9), 計9名
- Journal Title
  
  J Thorac Cardiovasc Surg 136(1)
  
  Pages: 142-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] A persistent infiltrated lung shadow inan infant : A rare association ofcongenital pulmonary venous obstructionwith partial anomalous pulmonary venousconnection and ventricular septaldefect2008
- Author(s)
  Iwasa T(1), Mitani Y(2), Shimpo H, (5), 計7名
- Journal Title
  
  Ped Int 50(3)
  
  Pages: 397-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Pulmonary artery growth after Norwood andbidirectional Glenn procedureInteract Cardiovasc Thorac Surg2008
- Author(s)
  Takabayashi S(1), Mitani Y(2), Shimpo H(4), 計4名
- Journal Title
  
  7(2)
  
  Pages: 328-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Fatal pulmonary lymphangiectasiamanifesting after repeated surgeries forintractable chylopericardium andchylothorax in a 20-month-old girl2008
- Author(s)
  Kamada N(1), Mitani Y(2), Shimpo H(10), 計11名
- Journal Title
  
  Circulation 117
  
  Pages: 1894-1896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Reduced regional right ventricular wallmotion after transventricular repair oftetralogy of Fallot2007
- Author(s)
  Takabayashi S(1), Shimpo H(2), Mitani Y(5)
- Journal Title
  
  J Thorac Cardiovasc Surg 133(6)
  
  Pages: 1656-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Fate of the 'opened' arterial duct:Lessons learned from bilateral pulmonaryartery banding for hypoplastic left heartsyndrome under the continuous infusion ofprostaglandin E12007
- Author(s)
  Mitani Y(1), Ohashi H(4), Maruyama K(8), Shimpo H(9)
- Journal Title
  
  J Thorac Cardiovasc Surg 133(6)
  
  Pages: 1653-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Palliative management of alow-birth-weight infant with congenitallycorrected transposition of the great arteries,severe restrictive foramen ovale,hypoplasia of the morphologically rightventricle, ventricular septal defect, andsteno-insufficiency of the tricuspidvalve2007
- Author(s)
  Takabayashi S(1), Shimpo H(2), Mitani Y(5)
- Journal Title
  
  Gen Thorac Cardiovasc Surg 55(4)
  
  Pages: 163-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Reversal of increased pulmonary arterialpressure associated with systemic venouscollaterals after tonsillectomy in aFontan candidate after Glenn procedure:Impact of obstructive sleep apnea onFontan circulation2007
- Author(s)
  Sawada H(1), Mitani Y(2), Shimpo H(7), Maruyama K(8)
- Journal Title
  
  J Thorac Cardiovasc Surg 133(5)
  
  Pages: 1371-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] A nuclear factor-κB inhibitor pyrrolidine dithiocarbamate ameriolates pulmonary hypertension in rats2007
- Author(s)
  Sawada H(1), Mitani Y(2), Shimpo H(8), Maruyama K(10)
- Journal Title
  
  Chest 132(4)
  
  Pages: 1265-1274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591202
[Journal Article] Specific inhibition of p38 mitogen-activated protein kinase with ER167653 attenuates vascular proliferation in monocrotaline-induced pulmonary hypertension in rats.2004
- Author(s)
  Jun Lu, Hideto Shimpo, Akira Shimamoto, Albert J.Chong, Craig R.Hampton, Denise J.Spring, Masaki Yada, Motoshi Takao, Koji Onoda, Isao Yada, Timothy H Pohlman, Edward D.Verrier
- Journal Title
  
  Journal of Thoracic and Cardiovascular Surgery 128(6)
  
  Pages: 850-859
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571261
[Presentation] モノクロタリン誘発肺高血圧ラットモデルにおけるテネイシンCの役割とシロスタゾールの効果の検討2015
- Author(s)
  真栄城亮、新保秀人
- Organizer
  第68回日本胸部外科学会定期学術集会
- Place of Presentation
  神戸ポートピアホテル(兵庫県・神戸市)
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-24592057
[Presentation] Eisenmenger 症候群を除く肺血管病変を伴う先天性心疾患に対するボセンタンの効果2009
- Author(s)
  大橋啓之(1)、三谷義英(2)、新保秀人(7)、計7名
- Organizer
  第44回日本小児循環器学会総会
- Place of Presentation
  郡山市
- Year and Date
  2009-07-02
- Data Source
  KAKENHI-PROJECT-19591202
[Presentation] Bosentan promotes incorporation of bone marrow-derived endothelial cells but inhibits infiltration of macrophages into pulmonary vascular lesions in mice exposed to chronic hypoxia : A novel concept of bosentan therapy in pulmonary hypertension2009
- Author(s)
  Kato T, Sawada H, Maruyama J, Ikeyama Y, Masuya M, Miyata E, Nakamura S, Shimpo H, Maruyama K, Komada Y, Mitani Y.
- Organizer
  American Heart Association
- Place of Presentation
  Orland (US)
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-21591385
[Presentation] Bosentan Promotes Incorporation of Bone Marrow-Derived Endothelial Progenitor Cells but Inhibits Infiltration of Macrophages into Pulmonary Vascular Lesions in Mice Exposed to Chronic Hypoxia : A New Mechanism of Bosentan in Inhibiting Pulmonary Hypertension2009
- Author(s)
  Kato T, Shimpo H, Maruyama K, Mitani Y.
- Organizer
  Japanese Circulation Society
- Place of Presentation
  大阪
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-19591202
[Presentation] Bosentan Promotes Incorporation of Bone Marrow-Derived Endothelial Progenitor Cells but Inhibits Infiltration of Macrophages into Pulmonary VascularLesions in Mice Exposed to ChronicHypoxia : A New Mechanism of Bosentan in Inhibiting Pulmonary Hypertension2009
- Author(s)
  Kato T(1), Shimpo H(9), Maruyama K(10), Mitani Y(12), 計12名
- Organizer
  Japanese Circulation Society
- Place of Presentation
  大阪
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-19591202
[Presentation] Chronic hypoxia increases bone marrow-derived endothelial cells of non-hematopoietic stem cell origin, as well as macrophages of hematopoietic stem cell origin, in pulmonary vascular. lesions in mice : differential roles of bone marrow-derived hematopoietic and non-hematopoietic stem cells in pulmonary hypertension2008
- Author(s)
  Kato T, Sawada H, Maruyama J, Masuya M, Mityata E, Nakamura S, Ikeyama Y, Shimpo H, Maruyama K, Komada Y, Mitani Y.
- Organizer
  American Heart Association
- Place of Presentation
  New Orleans, USA
- Year and Date
  2008-11-10
- Data Source
  KAKENHI-PROJECT-19591202
[Presentation] Chronic hypoxia increases bonemarrow-derived endothelial cells ofnon-hematopoietic stem cell origin, aswell as macrophages of hematopoietic stemcell origin, in pulmonary vascular lesionsin mice : differential roles of bonemarrow-derived hematopoietic andnon-hematopoietic stem cells in pulmonaryhypertension2008
- Author(s)
  Kato T(1), Shimpo H(8), Maruyama K(9), Mitani Y(11), 計11名
- Organizer
  American Heart Association, New Orleans
- Place of Presentation
  US
- Year and Date
  2008-11-10
- Data Source
  KAKENHI-PROJECT-19591202
[Presentation] 先天性心疾患の治療計画におけるSildenafil の有用性(第2報) : non-PH群での中期成績2008
- Author(s)
  三谷義英(1)、大橋啓之(2)、新保秀人(6)、計7名
- Organizer
  第44回日本小児循環器学会総会
- Place of Presentation
  郡山市
- Year and Date
  2008-07-02
- Data Source
  KAKENHI-PROJECT-19591202
[Presentation] マウス肺高血圧性血管病変における骨髄幹細胞の関与 : 間葉系幹細胞と血球系幹細胞の役割2008
- Author(s)
  加藤太一(1)、三谷義英(2)、丸山一男(8)、新保秀人(9)、計10名
- Organizer
  第44回日本小児循環器学会総会
- Place of Presentation
  郡山市
- Year and Date
  2008-07-02
- Data Source
  KAKENHI-PROJECT-19591202

1. YADA Isao (80093152)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
2. YOSHIHIDE Mitani (60273380)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
3. SHIMAMOTO AKIRA (90324524)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. MATSUO ERI (40751665)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KAZUO Maruyama (20181828)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
6. SHIMONO Takatsugu (80206242)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MAESHIRO RYO (90647124)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. TAKAO Motoshi (30263007)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. KUMAMOTO Tadashi (50362348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. GOTO TAKEHIRO (80774877)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HIRANO KOJI (40378394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KONUMA TAKESHI (40307559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TANI Kazuhiro (80263010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ONODA Koji (70260601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TOMITA MASAYUKI (90774860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 澤田博文 (30362354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. 武藤紹士 (30600829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 草川實 (10046336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIDETO Shimpo 新保 秀人

SHIMPO Hideto 新保 秀人

SHINPO Hideto 新保 秀人

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Specific inhibition of tenascin-C with Cilostazol attenuates vascular proliferation in monocrotaline-induced pulmonary hypertension in ratsPrincipal Investigator

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Important role of inflammation on drug induced pulmonary hypertensionPrincipal Investigator

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[Journal Article] Role of Heat Shock Proteins in Pharmacological Preconditioning for Lung Ischemia Reperfusion Injury2016

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[Journal Article] Acute effect of sildenafil on hypoxemic patients (excluding those with Eisenmenger syndrome) with incurable congenital heart disease and disturbed pulmonary vasculature in the mid-term follow-up2011

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[Journal Article] Acute effect of sildenafil on hypoxemic patients (excluding those with Eisenmenger syndrome) with incurable congenital heart disease and disturbed pulmonary vas culature in the mid-term follow-up2011

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[Journal Article] Postnatal course of hypoplastic left heart complex and restrictive foramen ovale2010

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HIDETO Shimpo 新保秀人

SHIMPO Hideto 新保秀人

SHINPO Hideto 新保秀人