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Sugiyama Eiji  杉山 英二

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… Alternative Names

SUGIYAMA EIJI  杉山 英二

SUGIYAMA Eiji  杉山 英二

杉山 英二  スギヤマ エイジ

SUGIYAMA Fiji  杉山 英二

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Researcher Number 70179167
Other IDs
Affiliation (Current) 2025: 広島大学, 病院(医), 名誉教授
Affiliation (based on the past Project Information) *help 2021: 広島大学, 病院(医), 名誉教授
2018 – 2020: 広島大学, 病院(医), 教授
2015 – 2016: 広島大学, 病院(医), 教授
2013 – 2014: 広島大学, 大学病院, 教授
2012 – 2013: 広島大学, 病院, 教授 … More
2012: 広島大学, 病院(医), 教授
2010: 富山大学, 大学院・医学薬学研究部(医学), 准教授
2008: 富山大学, 大学院・医学薬学研究部(医学), 准教授
2006: University of Toyama, Interna Medicine 1, Associate professor
2006: 富山大学, 大学院医学薬学研究部, 助教授
2005: 富山大学, 医学部, 助教授
2003 – 2004: 富山医科薬科大学, 医学部, 助教授
2001: Toyama Medical and Pharmaceutical University, Faculty of Medicine, Associate Professor, 医学部, 助教授
1999 – 2000: 富山医科薬科大学, 附属病院, 講師
1991 – 1992: 富山医科薬科大学, 医学部, 助手
1986: 富山医科薬科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
内科学一般 / Orthopaedic surgery / Basic Section 54020:Connective tissue disease and allergy-related / 膠原病・アレルギー・感染症内科学
Except Principal Investigator
膠原病・アレルギー・感染症内科学 / Basic Section 57030:Conservative dentistry-related / Collagenous pathology/Allergology / Biological Sciences
Keywords
Principal Investigator
破骨細胞 / 関節リウマチ / c-Fos / 滑膜細胞 / TNFα / adeno-associated virus / osteoclast / interleukin-4 / インターロイキン-4 / アデノ随伴ウイルス … More / 遺伝子療法 / インターロイキン4 / Rheumatoid arthritis / Interleukin-11 / Osteoclast / SKGマウス / 抗シトルリン化ペプチド抗体 / CXCL10 / LPS / シトルリン化フィブリノーゲン / モノクローナル抗体 / SKGマウス / 抗シトルリン化蛋白抗体 / PPARγ agonists / Interleukin-10 / PPARγ / インターロイキン-10 / rheumatoid arthritis / gene therapy / インターロイキンー10 / インターロイキンー4 / 遺伝子治療 / 間接リウマチ / NFATc1 / RAW264.7細胞 / Synovial cells / Synovial T cells / OCIF / ODF / 破骨細胞分化誘導因子 / Tリンパ球 / IL-11 / 慢性関節リウマチ / Synovial T cell / Synovial cell / Rheumatoid Arthritis / PPAR / PPAR / プロテアーゼ / サイトカイン / 上皮間葉移行 / 間葉系幹細胞 / 脂肪分化 … More
Except Principal Investigator
関節リウマチ / サイトカイン / 滑膜細胞 / IL-6 / マウス / RNA binding protein / RNA安定化タンパク質 / シトルリン化タンパク質 / 歯周病原細菌 / ケルセチン / 歯周病源細菌 / RNA結合タンパク質 / 歯周炎 / 3'非翻訳配列 / アプタマー / デュアルレポーター / 3'非翻訳領域 / RNA結合タンパク / AU rich element / mRNA / 発現制御 / AU-rich element / 3'UTR / mRNA制御 / 受容体 / mRNA崩壊 / locked nucleic acid / 翻訳制御 / 分化誘導 / miRNA / TGF / マイクロRNA / リウマチ学 / エピトープ / 抗体 / CCP / リンパ球チップシステム / ISAAC法 / マイクロウェルアレイチップ / 抗CCP抗体 / 自己抗体 / リウマチ / 自己免疫疾患 / 自己抗体遺伝子 / 細胞マイクロアレイ法 Less
  • Research Projects

    (13 results)
  • Research Products

    (51 results)
  • Co-Researchers

    (12 People)
  •  Development of inhibitors of osteoclast differentiation with an anti-citrullinated protein monoclonal antibodyPrincipal Investigator

    • Principal Investigator
      SUGIYAMA EIJI
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Hiroshima University
  •  The induced RNA-binding protein, HuR targets of IL-6 mRNA and enhances its stabilization in periodontitis

    • Principal Investigator
      Ouhara Kazuhisa
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Hiroshima University
  •  AU-rich element dependent mRNA regulation in functional change of rheumatoid arthritis synoviocyte

    • Principal Investigator
      Satoshi Yamasaki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Kurume University
      Hiroshima University
  •  Analyses of gene expressions related with rheumatoid arthritis and epithelial mesenchymal transition in fibroblast-like synoviocyte by adipogenesis.Principal Investigator

    • Principal Investigator
      SUGIYAMA EIJI
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Hiroshima University
  •  Reprograming of rheumatoid synovial cell function by miRNA

    • Principal Investigator
      YAMASAKI Satoshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Hiroshima University
      Nagasaki University
  •  Preparation of CCP antibodies library in Rheumatoid Arthritis and its clinical application

    • Principal Investigator
      KISHI Hiroyuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      University of Toyama
  •  possible therapeutic application of gene therapy of anti-inflammatory cytokines to rheumatoid joint destructionPrincipal Investigator

    • Principal Investigator
      SUGIYAMA Eiji
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      University of Toyama
  •  細胞マイクロアレイ法を用いた自己抗体遺伝子の同定および自己免疫疾患の病態解析

    • Principal Investigator
      KISHI Hiroyuki
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  Development of adeno-associated virus vector-mediated IL-4 gene delivery system for rheumatoid arthritisPrincipal Investigator

    • Principal Investigator
      SUGIYAMA Fiji
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  The role of interleukin 11 in bone resorption by rheumatoid synovial cellsPrincipal Investigator

    • Principal Investigator
      SUGIYAMA Eiji
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  慢性関節リウマチ滑膜細胞における抗リウマチ剤のIL-1誘導IL-6産生抑制効果Principal Investigator

    • Principal Investigator
      杉山 英二
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内科学一般
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  自己免疫疾患発症マウスにおける抗DNA抗体産生調節機構の解析Principal Investigator

    • Principal Investigator
      杉山 英二
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内科学一般
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  遅効性抗リウマチ剤の免疫学的研究(インターロイキン1産生能に及ぼす影響について)Principal Investigator

    • Principal Investigator
      杉山 英二
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内科学一般
    • Research Institution
      Toyama Medical and Pharmaceutical University

All 2021 2020 2019 2018 2016 2015 2014 2013 2007 2006 2005 2003 Other

All Journal Article Presentation Patent

  • [Journal Article] The Lipopolysaccharide Mutant Re-LPS Is a Useful Tool for Detecting LPS Contamination in Rheumatoid Synovial Cell Cultures2021

    • Author(s)
      Kohno Hiroki、Ouhara Kazuhisa、Mokuda Sho、Tokunaga Tadahiro、Sugimoto Tomohiro、Watanabe Hirofumi、Ishitoku Michinori、Yoshida Yusuke、Mizuno Noriyoshi、Ozawa Tatsuhiko、Kawataka Masatoshi、Hirata Shintaro、Kishi Hiroyuki、Sugiyama Eiji
    • Journal Title

      Pathobiology

      Volume: 89 Issue: 2 Pages: 92-100

    • DOI

      10.1159/000520022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K18499, KAKENHI-PROJECT-21H02962
  • [Journal Article] Nailfold capillaries and myositis specific antibodies in anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis2021

    • Author(s)
      Sugimoto, T. Mokuda, S. Kohno, H. Ishitoku, M. Araki, K. Watanabe, H. Tokunaga, T. Yoshida, Y. Hirata, S. Sugiyama, E.
    • Journal Title

      Rheumatology (Oxford)

      Volume: - Issue: 5 Pages: 2006-2015

    • DOI

      10.1093/rheumatology/keab681

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K18499
  • [Journal Article] Activin A Expressed in Rheumatoid Synovial Cells Downregulates TNFα-Induced CXCL10 Expression and Osteoclastogenesis2020

    • Author(s)
      Kuranobu T, Mokuda S, Oi K, Tokunaga T, Yukawa K, Kohno H, Yoshida Y, Hirata S, Sugiyama E
    • Journal Title

      Pathobiology

      Volume: - Issue: 3 Pages: 198-207

    • DOI

      10.1159/000506260

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K18499
  • [Journal Article] TGFβ1 Regulates Human RANKL-Induced Osteoclastogenesis via Suppression of NFATc1 Expression2020

    • Author(s)
      Tokunaga T, Mokuda S, Kohno H, Yukawa K, Kuranobu T, Oi K, Yoshida Y, Hirata S, Sugiyama E
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 3 Pages: 800-800

    • DOI

      10.3390/ijms21030800

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K18499
  • [Journal Article] Angiotensin-converting Enzyme 2, a SARS-CoV-2 Receptor, Is Upregulated by Interleukin 6 through STAT3 Signaling in Synovial Tissues.2020

    • Author(s)
      Mokuda S, Tokunaga T, Masumoto J, Sugiyama E.
    • Journal Title

      J Rheumatol.

      Volume: 47 Issue: 10 Pages: 2553-2558

    • DOI

      10.3899/jrheum.200547

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K18499, KAKENHI-PROJECT-20H03719
  • [Journal Article] Physiologic Target, Molecular Evolution, and Pathogenic Functions of a Monoclonal Anti-Citrullinated Protein Antibody Obtained From a Patient With Rheumatoid Arthritis.2020

    • Author(s)
      Ozawa T, Ouhara K, Tsuda R, Munenaga S, Kurihara H, Kohno H, Hamana H, Kobayashi E, Taki H, Tobe K, Sugiyama E, Muraguchi A, Kishi H.
    • Journal Title

      Arthritis Rheumatol.

      Volume: 72 Issue: 12 Pages: 2040-2049

    • DOI

      10.1002/art.41426

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08908, KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-18H02689, KAKENHI-PROJECT-18K09599
  • [Journal Article] Effect of Porphyromonas gingivalis infection on gut dysbiosis and resultant arthritis exacerbation in mouse model2020

    • Author(s)
      Hamamoto Yuta、Ouhara Kazuhisa、Munenaga Syuichi、Shoji Mikio、Ozawa Tatsuhiko、Hisatsune Jyunzo、Kado Isamu、Kajiya Mikihito、Matsuda Shinji、Kawai Toshihisa、Mizuno Noriyoshi、Fujita Tsuyoshi、Hirata Shintaro、Tanimoto Kotaro、Nakayama Koji、Kishi Hiroyuki、Sugiyama Eiji、Kurihara Hidemi
    • Journal Title

      Arthritis Research & Therapy

      Volume: 22 Issue: 1 Pages: 249-249

    • DOI

      10.1186/s13075-020-02348-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K10072, KAKENHI-PROJECT-20K09921, KAKENHI-PROJECT-20K18537, KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-18H02689, KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K18999, KAKENHI-PROJECT-19K24073
  • [Journal Article] Serum CXCL10 levels are associated with better responses to abatacept treatment of rheumatoid arthritis.2019

    • Author(s)
      Yukawa K, Mokuda S, Kohno H, Oi K, Kuranobu T, Tokunaga T, Yoshida Y, Yamana J, Iwahashi M, Hirata S, Yamana S, Sugiyama E.
    • Journal Title

      Clin Exp Rheumatol.

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08908
  • [Journal Article] Multiple External Root Resorption of Teeth as a New Manifestation of Systemic Sclerosis-A Cross-Sectional Study in Japan.2019

    • Author(s)
      Memida T, Matsuda S, Kajiya M, Mizuno N, Ouhara K, Fujita T, Hirata S, Yoshida Y, Sugimoto T, Nishi H, Kawaguchi H, Sugiyama E, Kurihara H.
    • Journal Title

      J Clin Med.

      Volume: Oct 4;8(10). Issue: 10 Pages: 1628-1628

    • DOI

      10.3390/jcm8101628

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09599
  • [Journal Article] The involvement of C5a in the progression of experimental arthritis with Porphyromonas gingivalis infection in SKG mice2018

    • Author(s)
      Munenaga Syuichi、Ouhara Kazuhisa、Hamamoto Yuta、Kajiya Mikihito、Takeda Katsuhiro、Yamasaki Satoshi、Kawai Toshihisa、Mizuno Noriyoshi、Fujita Tsuyoshi、Sugiyama Eiji、Kurihara Hidemi
    • Journal Title

      Arthritis Research & Therapy

      Volume: 20 Issue: 1

    • DOI

      10.1186/s13075-018-1744-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09599
  • [Journal Article] Reparative bone-like tissue formation in the tooth of a systemic sclerosis patient2018

    • Author(s)
      Matsuda S.、Memida T.、Mizuno N.、Ogawa I.、Ouhara K.、Kajiya M.、Fujita T.、Sugiyama E.、Kurihara H.
    • Journal Title

      International Endodontic Journal

      Volume: 26-28 Issue: 9 Pages: 12914-12914

    • DOI

      10.1111/iej.12914

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11390, KAKENHI-PROJECT-18K09599
  • [Journal Article] Tocilizumab induced acquired factor XIII deficiency in patients with rheumatoid arthritis.2013

    • Author(s)
      Mokuda S, Murata Y, Sawada N, Matoba K, Yamada A, Onishi M, Okuda Y, Jouyama K, Sugiyama E, Takasugi K.
    • Journal Title

      PLoS One.

      Volume: 8 Issue: 8 Pages: e69944-e69944

    • DOI

      10.1371/journal.pone.0069944

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591448
  • [Journal Article] Interleukin-iO inhibits RANKL-mediated expression of NFATcl in part via suppression of c-Fos and c-Jun in RAW264.7 cells and mouse bone marrow cells.2007

    • Author(s)
      Mohamed SG, Sugiyama E, Shinoda K, Taki H, Hounoki H, Abdel-Aziz HO, et. al.
    • Journal Title

      Bone 41(4)

      Pages: 592-602

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591557
  • [Journal Article] Isoproterenol suppresses cytokine-induced RANTES secretion in human lung epithelial cells through the inhibition of c-jun N-terminal kinase pathway2006

    • Author(s)
      Miyabayashi K, Maruyama M, Yamada T, Shinoda C, Hounoki H, Kanatani Y, Shinoda K, Kawagishi Y, Miwa T, Suzuki K, Arai N, Hayashi R, Matsui S, Sugiyama E, Kobayashi M.
    • Journal Title

      Biochem Biophys Res Commun 350(3)

      Pages: 753-61

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591557
  • [Journal Article] Ionizing radiation suppresses FAP-i mRNA level in A549 cells via p53 activation.2006

    • Author(s)
      Yamada T, Maruyama M, Fujita T, Miyabayashi K, Shinoda C, KawagishiY, Fujishita T, Hayashi R, Miwa T, Arai N, Matsui S, Sugiyama E, Kobayashi M.
    • Journal Title

      FEBS Lett 580(18)

      Pages: 4387-91

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591557
  • [Journal Article] Interleukin-4 inhibits RANKL-induced expression of NFATc1 and c-Fos : a possible mechanism for downregulation of osteoclastogenesis2005

    • Author(s)
      S.G.Kamel Mohamed, E.Sugiyama, K.Shinoda, H.Hounoki, H.Taki, M.Maruyama, T.Miyahara, M.Kobayashi
    • Journal Title

      Biochem Biophys Res Commun 329

      Pages: 839-845

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591570
  • [Journal Article] Interleukin-4 inihibits RANKL-induced expression of NFATc1 and c-Fos : A possible mechanism for downregulation of osteoclastogenesis2005

    • Author(s)
      Mohamed SGK, Sugiyama E, Shinoda K, et al.
    • Journal Title

      Biochemical and Biophysical Research Communications 329

      Pages: 839-845

    • Data Source
      KAKENHI-PROJECT-15591570
  • [Journal Article] Cooperative induction of 15-lipoxygenase in rheumatoid synovial cells by IL-4 and proinflammatory cytokines2003

    • Author(s)
      S.Harada, E.Sugiyama, S.Takebe, H.Taki, K.Shinoda, S.G.Mohamed, M.Maruyama, T.Hamazaki, M.Kobayashi
    • Journal Title

      Clin Exp Rheumatol 21

      Pages: 753-758

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591570
  • [Journal Article] Resting T cells negatively regulate osteoclast generation from peripheral blood monocytes2003

    • Author(s)
      K.Shinoda, E.Sugiyama, H Taki, S.Harada, T.Mino, M.Maruyama, M.Kobayashi
    • Journal Title

      Bone 33

      Pages: 711-720

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591570
  • [Journal Article] Activation of peroxisome proliferator-activated receptory inhibits TNF-mediated osteoclast differentiation in human peripheral monocytes in part via suppression of monocytechemoattractant protein-i expression.

    • Author(s)
      Hounoki H, Sugiyama E, Mohamed SG, Shinoda K, Taki H, Abdel-Aziz HO, Maruyama M, Kobayashi M, Miyahara T
    • Journal Title

      Bone (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591557
  • [Patent] 関節リウマチの処置薬2014

    • Inventor(s)
      山崎聡士、杉山英二、禹 済泰、車 炳允
    • Industrial Property Rights Holder
      広島大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-190312
    • Filing Date
      2014-09-18
    • Data Source
      KAKENHI-PROJECT-24591448
  • [Patent] 破骨細胞分化誘導抑制剤および破骨細胞分化誘導抑制法2005

    • Inventor(s)
      杉山 英二, 岸 裕幸, 朴木 博幸
    • Industrial Property Rights Holder
      富山医科薬科大学
    • Industrial Property Number
      2005-281831
    • Filing Date
      2005-09-28
    • Data Source
      KAKENHI-PROJECT-17591557
  • [Presentation] リウマチ滑膜細胞のTLR4活性化研究におけるLPSのコンタミネーションの検出に、変異型LPS・Re-LPSは有用である2021

    • Author(s)
      河野紘輝、應原一久、徳永忠浩、茂久田翔、水野智仁、小澤龍彦、川高正聖、平田信太郎、岸裕幸、杉山英二
    • Organizer
      第36回日本臨床リウマチ学会
    • Data Source
      KAKENHI-PROJECT-19K08908
  • [Presentation] Angiotensin-converting enzyme 2, a SARS-CoV-2 receptor, is upregulated by IL-6 via STAT3 signaling in synovial fibroblasts and lymphocytes.2021

    • Author(s)
      Sho Mokuda, Tadahiro Tokunaga, Junya Masumoto, Eiji Sugiyama
    • Organizer
      第65回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-19K08908
  • [Presentation] Usefulness of nailfold video-capillaroscopy for diagnosing patients positive for anti-centromere antibody.2021

    • Author(s)
      Tomohiro Sugimoto, Hiroki Kobayashi, Harumichi Suma, Yohei Hosokawa, Michinori Ishitoku, Hiroki Kohno, Hirofumi Watanabe, Tadahiro Tokunaga, Shinpei Ohnari, Yusuke Yoshida, Sho Mokuda, Shintaro Hirata, Eiji Sugiyama
    • Organizer
      第65回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-19K08908
  • [Presentation] 関節リウマチ患者由来抗シトルリン化ペプチド抗体を用いた破骨細胞分化抑制作用について2019

    • Author(s)
      應原 一久、宗永 修一、平田 信太郎、杉山 英二、栗原 英見
    • Organizer
      第63回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18K09599
  • [Presentation] 3’-UTR Reporter Systemを用いた関節リウマチ関連遺伝子制御機序の解明2016

    • Author(s)
      山崎聡士  吉田雄介  熊谷和彦  野島崇樹  杉山英二
    • Organizer
      第60回日本リウマチ学会総会・学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-26461463
  • [Presentation] 3´-Untranslated Region Reporter Systemを用いた関節リウマチ関連遺伝子制御機序の解明.2016

    • Author(s)
      山崎聡士、吉田雄介、熊谷和彦、野島崇樹、杉山英二
    • Organizer
      第60回日本リウマチ学会総会・学術集会
    • Place of Presentation
      横浜パシフィコ
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-26461463
  • [Presentation] interleukin-1β Stabilize CXCL2mRNA and increase its Expression.2016

    • Author(s)
      Satoshi Yamasaki, Yusuke Yoshida and Eiji Sugiyama
    • Organizer
      82th American College of Rheumatology
    • Place of Presentation
      Walter E. Washington Convention Center,Washington, D.C.,USA
    • Year and Date
      2016-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461463
  • [Presentation] IL-1βとIL-17AによるAU-rich elementを介したCXCL2 mRNAの制御.2016

    • Author(s)
      吉田雄介、山崎聡士、熊谷和彦、野島崇樹、杉山英二
    • Organizer
      第60回日本リウマチ学会総会・学術集会
    • Place of Presentation
      横浜パシフィコ
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-26461463
  • [Presentation] IL-1βと IL-17Aによる AU-rich element を介したCXCL2 mRNAの制御2016

    • Author(s)
      吉田雄介  山崎聡士  熊谷和彦  野島崇樹   杉山英二
    • Organizer
      第60回日本リウマチ学会総会・学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2016-04-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461463
  • [Presentation] Inhibition of Dickkopf1 Dampens Anti Osteogenic Effect of Fibroblast-like Synoviocytes2015

    • Author(s)
      Eiji Sugiyama, Yusuke Yoshida and Satoshi Yamasaki,
    • Organizer
      81th American College of Rheumatology
    • Place of Presentation
      Moscone Center,San Francisco,USA
    • Year and Date
      2015-11-06
    • Data Source
      KAKENHI-PROJECT-26461463
  • [Presentation] 滑膜線維芽細胞による骨芽細胞抑制の可能性.2015

    • Author(s)
      山崎聡士、野島崇樹、吉田雄介、熊谷和彦、杉山英二
    • Organizer
      第59回日本リウマチ学会総会・学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-23
    • Data Source
      KAKENHI-PROJECT-26461463
  • [Presentation] 滑膜細胞によるDKK1を介した骨芽細胞抑制の可能性2015

    • Author(s)
      山崎聡士、吉田雄介、野島崇樹、杉山英二
    • Organizer
      第43回日本臨床免疫学会総会,
    • Place of Presentation
      神戸
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-26461463
  • [Presentation] 脂肪分化誘導による滑膜細胞からのマトリックスメタロプロテアーゼ産生抑制2013

    • Author(s)
      山崎聡士、遠藤功二、熊谷和彦、野島祟樹、杉山英二
    • Organizer
      第41回日本臨床免疫学会総会
    • Place of Presentation
      海峡メッセ下関,山口市
    • Year and Date
      2013-11-27
    • Data Source
      KAKENHI-PROJECT-23591440
  • [Presentation] Changes in MMPs in Fibroblast-Like Synoviocytes Following Adipogenesis2013

    • Author(s)
      Satoshi Yamasaki, Kazuhiko Kumagai, Kouji Endo, Takaki Nojima and Eiji Sugiyama.
    • Organizer
      2013 ACR/ARHP Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-23591440
  • [Presentation] 抗IL-6受容体抗体(トシリズマブ)投与中の関節リウマチ患者における血液凝固第XIII因子活性の低下2013

    • Author(s)
      茂久田 翔、村田洋介、高杉 潔、杉山英二
    • Organizer
      第24回日本リウマチ学会 中国・四国支部学術集会
    • Place of Presentation
      米子市コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-24591448
  • [Presentation] 脂肪分化誘導による滑膜細胞からのマトリックスメタロプロテアーゼ産生抑制2013

    • Author(s)
      山崎聡士、岡田覚丈、遠藤功二、大岩 寛、野島祟樹、熊谷和彦、川上 純、杉山英二
    • Organizer
      第57回日本リウマチ学会総会・学術集会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-24591448
  • [Presentation] 肪分化誘導による 滑膜細胞からのマトリックスメタロプロテアーゼ産生抑制2013

    • Author(s)
      山崎聡士、岡田覚丈、遠藤功二、大岩 寛、野島祟樹、熊谷和彦、川上 純、杉山英二.
    • Organizer
      第57回日本リウマチ学会総会学術集会
    • Place of Presentation
      京都国際会館、京都.
    • Data Source
      KAKENHI-PROJECT-23591440
  • [Presentation] Changes in MMPs in Fibroblast-Like Synoviocytes Following Adipogenesis2013

    • Author(s)
      Satoshi Yamasaki, Kazuhiko Kumagai, Kouji Endo, Takaki Nojima and Eiji Sugiyama
    • Organizer
      79th American College of Rheumatology
    • Place of Presentation
      San Diego Convention Center,San Diego,USA
    • Data Source
      KAKENHI-PROJECT-23591440
  • [Presentation] Changes in MMPs in Fibroblast-Like Synoviocytes Following Adipogenesis.2013

    • Author(s)
      Satoshi Yamasaki, Kazuhiko Kumagai, Kouji Endo, Takaki Nojima and Eiji Sugiyama viocytes Following Adipogenesis.
    • Organizer
      79th American College of Rheumatology
    • Place of Presentation
      San Diego Convention Center (United States of America)
    • Data Source
      KAKENHI-PROJECT-24591448
  • [Presentation] 脂肪分化誘導による滑膜細胞からのマトリックスメタロプロテアーゼ産生抑制2013

    • Author(s)
      山崎聡士、遠藤功二、熊谷和彦、野島祟樹、杉山英二
    • Organizer
      第41回日本臨床免疫学会総会
    • Place of Presentation
      海峡メッセ下関
    • Data Source
      KAKENHI-PROJECT-24591448
  • [Presentation] 脂肪分化誘導による滑膜細胞からのマトリックスメタロプロテアーゼ産生抑制2013

    • Author(s)
      山崎聡士、岡田覚丈、遠藤功二、大岩寛、野島祟樹、熊谷和彦、川上純、杉山英二
    • Organizer
      第57回日本リウマチ学会総会学術集会
    • Place of Presentation
      京都国際会館、京都(ポスター)
    • Data Source
      KAKENHI-PROJECT-23591440
  • [Presentation] Interleukin-10 inhibits RANKL-mediated expression of NFATc1 in part via suppression of c-Fos and c-Jun in RAW264.7 cells and mouse bone marrow cells.2007

    • Author(s)
      Sugiyama E
    • Organizer
      The 25th Annual Meeting of the Japanese Society for Bone and Mineral Reasearch
    • Place of Presentation
      Osaka
    • Year and Date
      2007-07-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591557
  • [Presentation] IL-10はc-Fos,c-Junの発現抑制を介して破骨細胞の分化,誘導を抑制する2007

    • Author(s)
      杉山 英二
    • Organizer
      第25回日本骨代謝学会総会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2007-07-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591557
  • [Presentation] 15-d-PGJ2はTNFαに串るヒト単球の破骨細胞誘導を抑制する2006

    • Author(s)
      杉山 英二
    • Organizer
      第24回日本骨代謝学会総会
    • Place of Presentation
      東京ファッションタウン
    • Year and Date
      2006-07-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591557
  • [Presentation] 15-d PGJ2 inhibits TNFa-mediated osteoclastogenesis in human peripheral monocytes.2006

    • Author(s)
      Sugiyama E
    • Organizer
      The 24th Annual Meeting of the Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Tokyo
    • Year and Date
      2006-07-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591557
  • [Presentation] 天然PPARγリガントによる滑膜細胞の脂肪分化誘導と関節リウマチ治療への応用

    • Author(s)
      山崎聡士、禹 済泰、熊谷和彦、野島崇樹、杉山英二
    • Organizer
      第42回日本臨床免疫学会総会
    • Place of Presentation
      京王プラザホテル
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24591448
  • [Presentation] Satoshi Yamasaki and Eiji Sugiyama:Fibroblast-Like Synoviocytes Inhibit WNT Signaling Pathway by Secreting Dickkopf-1.

    • Author(s)
      Satoshi Yamasaki and Eiji Sugiyama
    • Organizer
      80th American College of Rheumatology
    • Place of Presentation
      Boston Convention & Exhibition Center(United States of America)
    • Year and Date
      2014-11-14 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-24591448
  • [Presentation] Arterpilin-CとMagnololによる滑膜細胞脂肪分化誘導

    • Author(s)
      山崎聡士、禹 済泰、熊谷和彦、遠藤功二、野島崇樹、杉山英二
    • Organizer
      第58回日本リウマチ学会総会・学術集会
    • Place of Presentation
      グランドプリンス新高輪 国際館パミール
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-24591448
  • [Presentation] 抗IL-6受容体抗体トシリズマブ投与中の関節リウマチ患者における血液凝固第XⅢ因子の欠乏

    • Author(s)
      茂久田 翔、村田洋介、高杉 潔、杉山英二
    • Organizer
      第58回日本リウマチ学会総会・学術集会
    • Place of Presentation
      グランドプリンス新高輪 国際館パミール
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-24591448
  • 1.  KISHI Hiroyuki (60186210)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  MURAGUCHI Atsushi (20174287)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  YAMASAKI Satoshi (30367388)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 19 results
  • 4.  OZAWA Tatsuhiko (10432105)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 5.  Ouhara Kazuhisa (80550425)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 6.  TAKI Hirofumi (10240780)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  SHINODA Koichiro (40377312)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KAWAKAMI Atsushi (90325639)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  鈴木 正康 (70226554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  清水 幸裕 (00235673)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  藤田 剛 (80379883)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  HIRATA Shintaro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results

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