Hashimoto Keiichiro 橋本敬一郎

… Alternative Names

HASHIMOTO Keiichiro 橋本敬一郎

橋本敬一郎ハシモトケイイチロウ

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Researcher Number	70192268
Other IDs
Affiliation (based on the past Project Information) *help	2014 – 2017: 藤田保健衛生大学, 総合医科学研究所, 教授 2007 – 2010: Fujita Health University, 総合医科学研究所, 教授 2000 – 2004: Fujita Health Univ.Inst.Comp.Med.Sci., Professor, 総合医科学研究所, 教授 1997 – 1999: 藤田保健衛生大学, 総合医科学研究所, 助教授 1995 – 1996: 藤田保健衛生大学, 総合医科学研究所, 講師 … More 1994: Inst. for Comprehensive Med. Sci. Fujita Health Univ. Associate Prof., 総医研, 講師 1991 – 1993: 藤田保健衛生大学, 総合医科学研究所, 講師 1989: 保健衛生大学, 医学部・総医研, 助手 1987: 藤田学園保健衛生大学, 医学部・免疫学, 助手 Less
Review Section/Research Field	Principal Investigator Immunology / Molecular biology / Immunology / Evolutionary biology / Evolutionary biology Except Principal Investigator 分子遺伝学・分子生理学 / Immunology / General fisheries
Keywords	Principal Investigator MHC / 分子進化 / クラスI / molecular evolution / 多型性 / 魚類 / polymorphism / class I / 進化 / 獲得免疫 … More / 脊椎動物 / クラスII / 抗原提示 / class II / MR1 / 主要組織適合性抗原 / natural immunity / molecular family / primitive / antigen presentation / vertebrates / acquired immune system / ドメイン / 免疫システム / 自然免疫 / 原始的 / 分子ファミリー / cartilaginous fish / acquired immunity / Class I / 軟骨魚類 / T cell receptor / conservation / linkage / 遺伝子構造 / T細胞レセプター / 保存性 / 連鎖 / クラス I / リガンド / 肉鰭類 / DM分子 / クラスII分子 / ペプチド積載機構 / 獲得免疫機構 / lungfish / antigen / fish / evolution / immune-system / peptide-loading / 主要組織適合遺伝子複合体 / 免疫学 / 生体分子 / ゲノム / 有顎脊椎動物 / 獲得免疫系 / 遺伝子 / 生体防御 / 免疫 / PCR … More Except Principal Investigator 進化 / MHC / Suncus murinus / IgM- and IgG- double bearing cell / immunoglobulin gene / cDNAライブラリー / X染色体 / RFLP解析 / 組み換え酵素 / DNA再編成 / 先天性免疫不全症 / RNAポリメラーゼIII / RNAスプライシング / tRNA / 多様性 / D_H遺伝子 / 免疫グロブリン / hyper IgMimmunodeficiency / IgM-、IgG二重表現株 / トランススプライシング / ヒトIgD産生株 / ジャコウネズミ / hypre IgM immunodeficioncy / IgM-,IgG二重表現株 / 免疫グロブリン遺伝子 / evolution / MR1 gene / human / elasmoblanch / cyprinid fish / MHC class I genes / アロ認識 / 組織特異性 / 分子進化 / 遺伝子ファミリー / PCR / 免疫の系統発生 / MHCクラスI分子 / MHC遺伝子 / MR1遺伝子 / ヒト遺伝子 / 軟骨魚 / コイ科魚類 / MHCクラスI遺伝子 / Sponge / Homeobox / Immune system / Complement / 補体第二経路 / 円口類 / 抗体 / 海綿 / ホメオボックス / 免疫系 / 補体 / 生体分子 / ゲノム / 遺伝子 / 免疫学 / 水産学 / 細胞表面マーカー / Tリンパ球 / CD4 / 免疫学的予防 / 魚病 / InTー6 / T細胞レセプター遺伝子 / PFG法 / 遺伝子増幅 / Nーmyc遺伝子 / Neuroblastoma Less

Molecular evolution of the MHC peptide-loading systemPrincipal Investigator
- Principal Investigator
  
  Hashimoto Keiichiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Evolutionary biology
- Research Institution
  Fujita Health University
Elucidation of the molecular evolution of the major histocompatibility complex (MHC) molecule, critical for the defense system of the jawed vertebratesPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Keiichiro
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Evolutionary biology
- Research Institution
  Fujita Health University
Elucidation of fish T lymphocyte subgroup based on the CD4 family marker
- Principal Investigator
  
  J・M Dijkstra
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General fisheries
- Research Institution
  Fujita Health University
Elucidation of the molecular evolution of MHC family and the establishment of the acquired immune systemPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Keiichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Fujita Health University
Studies on the molecular evolution of MHC class I genes and their polymorphismPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Keiichiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Fujita Health University
MHC関連遺伝子群の解析Principal Investigator
- Principal Investigator
  
  橋本敬一郎
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Fujita Health University
Studies on the molecular evolution of MHC class I genes and their polymorphismPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Keiichiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Fujita Health University
MHC関連遺伝子群の解析Principal Investigator
- Principal Investigator
  
  橋本敬一郎
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Fujita Health University
新しいヒトMHC関連遺伝子群の解析Principal Investigator
- Principal Investigator
  
  橋本敬一郎
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Fujita Health University
Studies on the molecular evolution of MHC class I genes and their polymorplusinPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Keiichiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Fujita Health University
新しいヒトMHC関連遺伝子群の解析Principal Investigator
- Principal Investigator
  
  橋本敬一郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Fujita Health University
NHCクラス工遺伝子の分子進化と多型性獲得機構の解明Principal Investigator
- Principal Investigator
  
  橋本敬一郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Fujita Health University
新しいヒトMHC関連遺伝子の解析Principal Investigator
- Principal Investigator
  
  橋本敬一郎
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Fujita Health University
自己・非自己識別機構の分子進化Principal Investigator
- Principal Investigator
  
  橋本敬一郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Fujita Health University
Analysis of molecular basis for allo-recognition
- Principal Investigator
  
  KUROSAWA Yoshikazu
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Institute for Comprehensive Medical Science, Fujita Health Univ.
自己・非自己識別機構の分子進化Principal Investigator
- Principal Investigator
  
  橋本敬一郎
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Fujita Health University
Construction and expression of gene families
- Principal Investigator
  
  KUROSAWA Yoshikazu
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Fujita Health University
癌細胞における染色体変異の分子機構の解析
- Principal Investigator
  
  KUROSAWA Yoshikazu
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Fujita Health University
Analysis of the genes in lymphocyte differentiation.
- Principal Investigator
  
  KUROSAWA Yoshikazu
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  FUJITA-GAKUEN HEALTH UNIVERSITY

All 2011 2010 2009 2008 2007 2003 Other

All Journal Article Presentation

[Journal Article] Constitutive high expression of interleukin-4/13A and GATA-3 in gill and skin ofsalmonid fishes suggests that these tissues form Th2-skewed immune environments.2011
- Author(s)
  Takizawa F, Koppang EO, Ohtani M, Nakanishi T, Hashimoto K, Fischer U, Dijkstra JM.
- Journal Title
  
  Mol.Immunol. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570223
[Journal Article] A molecule in teleost fish, related with human MHC-encoded G6F, has a cytoplasmic tail with ITAM and marks the surface of thrombocytes and in some fishes also of erythrocytes.2010
- Author(s)
  Ohashi K, Takizawa F, Tokumaru N, Nakayasu C, Toda H, Fischer U, Moritomo T, Hashimoto K, Nakanishi T, Dijkstra JM.
- Journal Title
  
  Immunogenetics 62
  
  Pages: 543-559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570223
[Journal Article] Zinc-dependent binding between peptides derived from rainbow trout CD8alpha and LCK.2010
- Author(s)
  Hayashi N, Takeuchi M, Nakanishi T, Hashimoto K, Dijkstra JM.
- Journal Title
  
  Fish Shellfish Immunol. 28
  
  Pages: 72-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570223
[Journal Article] Zinc-dependent binding between peptides derived from rainbow trout CD8a and LCK.2010
- Author(s)
  Hayashi N, Takeuchi M, Nakanishi T, Hashimoto K, Dijkstra JM.
- Journal Title
  
  Fish Shellfish Immunology 28
  
  Pages: 72-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580220
[Journal Article] Comprehensive clarification of two paralogous interleukin 4/13 loci in teleost fish.2008
- Author(s)
  Ohtani M, Hayashi N, Hashimoto K, Nakanishi T, Dijkstra JM.
- Journal Title
  
  Immunogenetics 60
  
  Pages: 383-397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580220
[Journal Article] Comprehensive clarification of two paralogous interleukin 4/13 loci in teleost fish.2008
- Author(s)
  Ohtani M, Hayashi N, Hashimoto K, Nakanishi T, Dijkstra JM.
- Journal Title
  
  Immunogenetics 60
  
  Pages: 383-397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570223
[Journal Article] Comprehensive clarification of two paralogous interleukin 4/13 loci in teleost fish2008
- Author(s)
  Ohtani M, Hayashi N, Hashimoto K, Nakanishi T, Dijkstra JM.
- Journal Title
  
  Immunogenetics 60
  
  Pages: 383-397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570223
[Journal Article] Molecular cloning of C4 gene and identification of the class III complement region in the shark MHC.2003
- Author(s)
  Terado, T., Okamura, K., Ohta, Y., Shin, D.-H., Smith, S.L., Hashimoto, K., Takemoto, T., Nonaka, M., Kimura, H., Flajnik, M.F., Nonaka, M.
- Journal Title
  
  J.Immunol. 171
  
  Pages: 2461-2466
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590443
[Journal Article] A molecule in teleost fish, related with human MHC-encoded G6F, has a cytoplasmic tail with ITAM and marks the surface of thrombocytes and in some fishes also of erythrocytes.
- Author(s)
  Ohashi K, Takizawa F, Tokumaru N, Nakayasu C, Toda H, Fischer U, Morimoto T, Hashimoto K, Nakanishi T, Dijkstra JM.
- Journal Title
  
  Immunogenetics (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580220
[Presentation] Molecular characteristics of the leukocyte markers CD4-1, CD4-2, LAG-3, CD8alpha and CD8beta in teleost fish.2009
- Author(s)
  Dijksta JM, Hashimoto K.
- Organizer
  日本比較免疫学会
- Place of Presentation
  藤沢
- Year and Date
  2009-08-04
- Data Source
  KAKENHI-PROJECT-19580220
[Presentation] Molecular characteristics of the leukocyte markers CD4-1, CD4-2, LAG-3, CD8alpha and CD8beta in teleost fish.2009
- Author(s)
  Dijkstra JM, Hayashi N, Nakanishi T, Hashimoto K.
- Organizer
  日本比較免疫学会
- Place of Presentation
  藤沢
- Year and Date
  2009-08-04
- Data Source
  KAKENHI-PROJECT-19570223
[Presentation] Evolution of cytokines important for T helper cell differentiation.2008
- Author(s)
  Dijksta JM, Ohtani M, Hayashi N, Nakanishi T, Hashimoto K.
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19580220
[Presentation] Evolution of cytokines important for T helper cell differentiation.2008
- Author(s)
  Dijkstra JM, Ohtani M, Hayashi N, Nakanishi T, Hashimoto K.
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19570223
[Presentation] Unique features of major histocompatibility complex (MHC) genes in fish.2007
- Author(s)
  Dijkstra JM, Hashimoto K.
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19570223
[Presentation] Unique features of major histocompatibility complex (MHC) genes in fish.2007
- Author(s)
  Dijksta JM, Hashimoto K.
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19580220

1. DIJKSTRA J・M (10387681)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
2. KUROSAWA Yoshikazu (10109259)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. OKAMURA Kazuhiko (60132255)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. YAMAGUCHI Hisateru (70319250)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HAYASHI Nobuhiro (80267955)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. NAKANISHI Teruyuki (00322496)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. NAITO Kazuhiro (80132257)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 井野晶夫 (80121432)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MATSUI Toshikazu (50181681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 祖父江良 (70216589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 加藤浩 (10169518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 塚本健太郎 (00582818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 伊藤渉 (50192498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 松村宏 (50157278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 市原慶和 (80176304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 朝倉義博 (80175843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hashimoto Keiichiro 橋本 敬一郎

HASHIMOTO Keiichiro 橋本 敬一郎

橋本 敬一郎 ハシモト ケイイチロウ

Research Projects

Research Products

Co-Researchers

Molecular evolution of the MHC peptide-loading systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the molecular evolution of the major histocompatibility complex (MHC) molecule, critical for the defense system of the jawed vertebratesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of fish T lymphocyte subgroup based on the CD4 family marker

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the molecular evolution of MHC family and the establishment of the acquired immune systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the molecular evolution of MHC class I genes and their polymorphismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MHC関連遺伝子群の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Studies on the molecular evolution of MHC class I genes and their polymorphismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MHC関連遺伝子群の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

新しいヒトMHC関連遺伝子群の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Studies on the molecular evolution of MHC class I genes and their polymorplusinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しいヒトMHC関連遺伝子群の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

NHCクラス工遺伝子の分子進化と多型性獲得機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しいヒトMHC関連遺伝子の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hashimoto Keiichiro 橋本敬一郎

HASHIMOTO Keiichiro 橋本敬一郎

橋本敬一郎ハシモトケイイチロウ