iwasaki naoko 岩崎直子

… Alternative Names

Iwasaki Naoko 岩崎直子

IWASAKI Naoko 岩崎直子

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Researcher Number	70203370
Other IDs
External Links
Affiliation (Current)	2026: 東京女子医科大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 東京女子医科大学, 医学部, 特任教授 2021 – 2022: 東京女子医科大学, 医学部, 教授 2018 – 2019: 東京女子医科大学, 医学部, 教授 2017: 東京女子医科大学, 医学部, 准教授 2010 – 2012: 東京女子医科大学, 医学部, 准教授 2007 – 2008: Tokyo Women's Medical University, 医学部, 准教授 1998 – 2004: 東京女子医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Biological Sciences / Basic Section 45010:Genetics-related / Medical genome science / Metabolomics / Medical genome science / Human genetics Except Principal Investigator Metabolomics / Metabolomics
Keywords	Principal Investigator MODY / 2型糖尿病 / 糖尿病 / 全ゲノム解析 / ゲノム / 遺伝子 / monogenic diabetes / 若年発症糖尿病 / SNP / 多因子疾患 … More / 罹患同胞対法 / 網羅的 / 機能解析 / 原因遺伝子 / 網羅的解析 / 糖尿病網膜症 / 罹患同胞対 / HNF / ミトコンドリア遺伝子 / 発症機序 / precision medicine / Copy Number Variation / 精密医療 / MLPA / WES / 単一遺伝子病 / 単一遺伝子疾患 / ゲノム医療 / targeted sequencing / 単一遺伝子異常 / 個別化医療 / 次世代シーケンサー / 単一遺伝子糖尿病 / Calpain 10 / Mitochondrial gene / mutation / hepatocyte nuclear factor / gene / type 2 diabetes / genome-wide scan / HNF-1β / MODY4 / 1PF-1 / NKX2,2 / NEUROD1 / BETA2 / NIDDM / β3 adrenergic receptor / 妊婦糖尿病 / 体重増加 / HNF1β / MODY5 / 疾患感受性遺伝子座位 / 羅患同胞対法 / カルパイン10 / NIDDM1 / 発症遺伝子 / 疾患感受性座位 / 日本人2型糖尿病 / 全ゲノムスギャン / ESRD / 罹患同胞対(法) / 感受性多型 / ミトコンドリア内膜pH / 単一遺伝 / RCNJ15 / LSS / KCNJ15 / ｉＰＳ細胞 / ミトコンドリア / β細胞 / iPS / 次世代シークエンサー / 創薬 / 2 型糖尿病 / large deletion / HNF-4α / 薬剤応答遺伝子 / 2型糖尿病感受性遺伝子 / VEGF遺伝子 / MafA / マイクロアレイ / siRNA / ポジショナルクローニング / 巨大欠失 / VEGF / 網膜症 / 遺伝子多型 / 感受性遺伝子 / 薬剤反応性 / 人類学 / 内科 / 臨床 / 遺伝学 / サブ解析 / BMI / QTL / 多点解析 / マイクロサテライト / 日本人 / 腎障害 / 多因子遺伝 … More Except Principal Investigator MODY / HNF4α / PPAR-γ / PC-1 / Ca^<2+> oscillations / green fluorescent protein / insulin secreting cell / ミトコンドリア機能 / 細胞内局在 / PH可視化測定 / β細胞 / GFP / ミトコンドリア / pH可視化測定 / Diabetes Mellitus / SHP / HNF4 α / 転写因子 / 糖尿病 / affected sib-pair analysis / insulin sensitizer / insulin resistance / type 2 diabetes mellitus / TNF-α / インスリン抵抗性改善剤 / イスンリン抵抗性 / インスリン非依存型糖尿病 / 罹患同胞対法 / インスリン抵抗性改善薬 / 罹忠同胎対法 / インスリン抵抗性改善策 / インスリン抵抗性 / 2型糖尿病 Less

A comprehensive genomic investigation of monogenic diabetes via whole-genome sequencingPrincipal Investigator
- Principal Investigator
  
  岩崎直子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  Tokyo Women's Medical University
A comprehensive genomic investigation of monogenic diabetes via whole-genome sequencingPrincipal Investigator
- Principal Investigator
  
  Iwasaki Naoko
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  Tokyo Women's Medical University
Complihensive analysis for causative genes in unknown monogenic diabetesPrincipal Investigator
- Principal Investigator
  
  Iwasaki Naoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical genome science
- Research Institution
  Tokyo Women's Medical University
Searching for the causative genes and susceptibility SNPs for diabetes mellitus based on the linkage analysis dataPrincipal Investigator
- Principal Investigator
  
  IWASAKI Naoko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical genome science
- Research Institution
  Tokyo Women's Medical University
Study for the Genetics of diabetes mellitus and its complications with one large hospital based cohortPrincipal Investigator
- Principal Investigator
  
  IWASAKI Naoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Women's Medical University
全ゲノム解析結果に基づいた2型糖尿病候補遺伝子解析と糖尿病網膜症関連遺伝子の解析Principal Investigator
- Principal Investigator
  
  岩崎直子
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
全ゲノム解析結果に基づいた2型糖尿病候補遺伝子の解析と糖尿病網膜症関連遺伝子の解析Principal Investigator
- Principal Investigator
  
  岩崎直子
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
Mithochondrial pH in virtal inslinoma cell line INS-1 with glucose stimulant Ca release
- Principal Investigator
  
  OGATA Makiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tokyo Women's Medical University
日本人2型糖尿病原因遺伝子の全ゲノム解析結果に基づいた2型糖尿病候補遺伝子の検討Principal Investigator
- Principal Investigator
  
  岩崎直子
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
日本人2型糖尿病原因遺伝子の全ゲノムレベル解析とクローニングPrincipal Investigator
- Principal Investigator
  
  岩崎直子
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
Study for onset of MODY, by gene mutation of transcriptional factor, using cellular localization
- Principal Investigator
  
  OGATA Makiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tokyo Women's Medical University
日本人2型糖尿病原因遺伝子の全ゲノムレベル解析Principal Investigator
- Principal Investigator
  
  岩崎直子
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
インスリン感受性からみたインスリン非依存型糖尿病の成因に関する遺伝学的研究
- Principal Investigator
  
  IWAMOTO Yasuhiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Tokyo Women's Medical University
Searching for the responsible genes for developing type 2 diabetes mellitus in JapanesePrincipal Investigator
- Principal Investigator
  
  NAOKO Iwasaki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tokyo Women's Medical University

[Book] 遺伝医学　朝倉内科学　12版2022
- Author(s)
  岩崎直子
- Publisher
  朝倉出版
- ISBN
  9784254322804
- Data Source
  KAKENHI-PROJECT-21K06281
[Book] ガイドラインにないリアル糖尿病薬物療法をガイドする（部分執筆、「ミトコンドリア糖尿病」）2022
- Author(s)
  岩崎直子
- Publisher
  新興医学出版社
- Data Source
  KAKENHI-PROJECT-21K06281
[Book] ミトコンドリア糖尿病の臨床的特徴と診断基準2011
- Author(s)
  尾形真規子、岩崎直子
- Total Pages
  621
- Publisher
  総号医学社
- Data Source
  KAKENHI-PROJECT-22510214
[Book] (タイトル)新規アジア人2型糖尿病感受性遺伝子KCNJ15(書名)糖尿病学20112011
- Author(s)
  岩崎直子、岡本好司、徳永勝士(分担執筆)
- Total Pages
  146
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-22510214
[Book] (タイトル)KCNJ15遺伝子(書名)糖尿病とヒトゲノムQ&A2011
- Author(s)
  岩崎直子(分担執筆)
- Total Pages
  150
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-22510214
[Book] 糖尿病学2011
- Author(s)
  岩崎直子、岡本好司、徳永勝士
- Total Pages
  146
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-22510214
[Book] 糖尿病とヒトゲノム Q&A2011
- Author(s)
  岩崎直子
- Total Pages
  150
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-22510214
[Book] 糖尿病診療2010
- Author(s)
  岩崎直子
- Publisher
  日本医師会雑誌
- Data Source
  KAKENHI-PROJECT-22510214
[Book] 糖尿病ナビゲーター2010
- Author(s)
  岩崎直子
- Total Pages
  473
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-22510214
[Book] 糖尿病ナビゲーター第2版門脇孝編第2章 20.MODY pp144-1452010
- Author(s)
  岩崎直子
- Total Pages
  473
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-22510214
[Book] 糖尿病学の進歩2010
- Author(s)
  岩崎直子
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-22510214
[Book] 2型糖尿病遺伝子 p311-314「カラー版糖尿病学基礎と臨床」2007
- Author(s)
  岩崎直子(分担執筆)
- Total Pages
  1373
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-19590338
[Book] 2型糖尿病遺伝子 p:121-126「糖尿病学の療養指導2007 療養指導士を育てるために」2007
- Author(s)
  岩崎直子(分担執筆)
- Total Pages
  210
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-19590338
[Book] 新糖尿病眼科学一日一課2004
- Author(s)
  岩崎直子(分担)
- Total Pages
  210
- Publisher
  メディカル葵出版
- Data Source
  KAKENHI-PROJECT-16012261
[Journal Article] Two novel pathogenic PDX1 variants in two Japanese patients with maturity-onset diabetes of the young2025
- Author(s)
  Satoshi Tanaka, Hiroyuki Akagawa, Michiyo Hase, Naoko Iwasaki
- Journal Title
  
  Human Genome Variation
  
  Volume: *
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06281
[Journal Article] High prevalence of copy number variations in the Japanese participants with suspected MODY2024
- Author(s)
  Satoshi Tanaka1Satoshi Tanaka, Kenkou Azuma, Sayaka Higuchi, Atsushi Ujiie, Koshi Hashimoto, Naoko Iwasaki
- Journal Title
  
  Clinical Genetics
  
  Volume: ｘ Issue: 3 Pages: 1-12
- DOI
  10.1111/cge.14544
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06281
[Journal Article] A novel pathogenic variant in the glucokinase gene found in two Japanese siblings with maturity-onset diabetes of the young 22023
- Author(s)
  Satoshi Tanaka, Hiroyuki Akagawa, Kenkou Azuma, Kaoru Watanabe, Sayaka Higuchi, Naoko Iwasaki
- Journal Title
  
  Endocr J
  
  Volume: 70 Issue: 6 Pages: 629-634
- DOI
  10.1507/endocrj.EJ22-0541
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06281
[Journal Article] 単一遺伝子による糖尿病の診断－MIDD，MODYなどの遺伝子診断をどのように進めるか2022
- Author(s)
  岩崎直子
- Journal Title
  
  糖尿病・内分泌代謝科
  
  Volume: 55 Pages: 728-735
- Data Source
  KAKENHI-PROJECT-21K06281
[Journal Article] ルーブリック評価概論2021
- Author(s)
  岩崎直子
- Journal Title
  
  遺伝子医学
  
  Volume: 11 Pages: 66-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06281
[Journal Article] Expression of mutant mRNA and protein in pancreatic cells derived from MODY3- iPS cells2019
- Author(s)
  Shigeharu G. Yabe1, Junko Nishida, Satsuki Fukuda, Fujie Takeda, Kiyoko Nasiro, Kazuki Yasuda, Naoko Iwasaki, Hitoshi Okochi
- Journal Title
  
  PLOS ONE
  
  Volume: accepted
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07258
[Journal Article] Low resting energy expenditure in postmenopausal Japanese women with type 2 diabetes mellitus2019
- Author(s)
  Ide Risa, Ogata Makiko, Iwasaki Naoko, Babazono Tetsuya
- Journal Title
  
  Diabetology International
  
  Volume: 10 Issue: 4 Pages: 268-278
- DOI
  10.1007/s13340-019-00391-z
- NAID
  40022039939
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07258
[Journal Article] Diagnosis and Genetic Counseling for Mitochondrial Disease at the Institute of Medical Genetics, Tokyo Women's Medical University2018
- Author(s)
  Mari MATSUO, Naoko IWASAKI, Kayoko SAITO
- Journal Title
  
  Tokyo Women's Medical University Journal
  
  Volume: 2 Issue: 0 Pages: 6-13
- DOI
  10.24488/twmuj.2018003
- NAID
  130007537173
- ISSN
  2432-6186
- Year and Date
  2018-12-20
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07258
[Journal Article] Localization of hepatocyte nuclear factor-4a in the nucleolus and nucleus is regulated by its C-terminus2012
- Author(s)
  Ogata M, Awaji T, Iwasaki N, et al.
- Journal Title
  
  J Diabet Invest
  
  Volume: 3 Pages: 449-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] Whole gene deletion mutation of HNF1B and exonic aberration of GCK and HNF1B in patients with MODY in Japan2012
- Author(s)
  Takizawa M, Iwasaki N, Toshiyuki Y, Iwamoto Y, Uchigata Y
- Journal Title
  
  Diabetology International
  
  Volume: 3 Pages: 224-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] A new mitochondrial pH biosensor for quantitative assessment of pancreatic β-cell function2012
- Author(s)
  Ogata M, Awaji T, Iwasaki N et al
- Journal Title
  
  Biochemical and Biophysical Res Comm
  
  Volume: 421 Pages: 20-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] A new mitochondrial pH biosensor for quantitative assessment of pancreatic β-cell function2012
- Author(s)
  Ogata M, Awaji T, Iwasaki N. Fujimaki R, Takizawa M, Maruyama K, Iwamoto Y, Uchigata Y
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] A new mitochondrial pH biosensor for quantitative assessment of pancreatic β-cell function2012
- Author(s)
  Ogata M, Awaji T, Iwasaki N, Fujimaki R, Takizawa M, Maruyama K, Iwamoto Y, Uchigata Y
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 421 Pages: 20-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] Inhibition of Glucose-stimulated Insulin Secretion by KCNJ15, a Newly Identified Susceptibility Gene for Type 2 Diabetes2012
- Author(s)
  Okamoto K, Iwasaki N, Doi K, Noiri E, Iwamoto Y, Uchigata Y, Tokunaga K
- Journal Title
  
  Diabetes
  
  Volume: 61(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] Localization of hepatocyte nuclear factor-4a in the nucleolus and nucleus is regulated by its C-terminus.2012
- Author(s)
  Ogata M, Awaji T, Iwasaki N, Fujimaki R, Takizawa M, Maruyama K, Bell GI, Iwamoto Y, Uchigata Y
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 3 Pages: 449-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] Whole gene deletion mutation of HNF1B and exonic aberration mutations of GCK and HNF1B in patients with MODY in Japan2012
- Author(s)
  Takizawa M, Iwasaki N, Yamamoto T, Iwamoto Y, Uchigata Y
- Journal Title
  
  Diabetology International
  
  Volume: 特別号(Second revised)
- NAID
  10030590170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] Whole gene deletion mutation of HNF1B and exonic aberration of GCK and HNF1B in patients with MODY in Japan2012
- Author(s)
  Takizawa M, Iwasaki N, Toshiyuki Y, Iwamoto Y, Uchigata Y
- Journal Title
  
  Diabetol Int
  
  Volume: 3 Pages: 224-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] Inhibition of Glucose stimulated insulin secretion by KCNJ15, a newly identified susceptibility gene for type 2 diabetes mellitus2012
- Author(s)
  Okamoto K, Iwasaki N, Noiri E, Doi K, Iwamoto Y, Fujita T, Tokunaga K
- Journal Title
  
  Diabetes
  
  Volume: 61 Pages: 1734-1741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] WFS1複合ヘテロ変異を認めたWolfram症候群女性の長期予後と医療管理2011
- Author(s)
  藤巻理沙、岩崎直子, 他
- Journal Title
  
  東京女子医科大学雑誌
  
  Volume: 特別号 Pages: 241-246
- NAID
  110008441475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] 複雑性尿路感染症を合併したMODY5の1例2011
- Author(s)
  青木絵麻、岩崎直子, 他
- Journal Title
  
  東京女子医科大学雑誌
  
  Volume: 特別号 Pages: 247-252
- NAID
  110008441476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] 糖尿病の遺伝素因2011
- Author(s)
  岩崎直子
- Journal Title
  
  東京女子医科大学雑誌
  
  Volume: 特別号 Pages: 6-13
- NAID
  110008441447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] 糖尿病関連遺伝子2010
- Author(s)
  岩崎直子
- Journal Title
  
  臨床検査
  
  Volume: 54 Pages: 987-997
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] Genetic Polymorphisms in the Organic Cation Transporter 1, OCT1, in Chinese and Japanese Populations, Exhibit Altered Function2010
- Author(s)
  Chen L, Takizawa M, Chen E, Iwasaki N,and Giacomini KM
- Journal Title
  
  J Pharmacol ExpTherap
  
  Volume: 335(1) Pages: 42-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] Genetic Polymorphisms in the Organic Cation Transporter 1, OCT1, in Chinese and Japanese Populations, Exhibit Altered Function2010
- Author(s)
  Chen L, Takizawa M, (5名略) Kubo M, Nakamura S, Iwamoto Y, Iwasaki N, Giacomini KM
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 335 Pages: 42-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus2010
- Author(s)
  Okamoto K, Iwasaki N, Tokunaga K.
- Journal Title
  
  Am J Hum Genet
  
  Volume: 86 Pages: 54-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] The over 50 year clinical course of a patient with slowly progressive type 1 diabetes (SPIDDM)2010
- Author(s)
  Yanagisawa K, Omori Y, Fukushima S, Iwasaki N, Hashimoto N, Iwamoto Y
- Journal Title
  
  Endocrine Journal
  
  Volume: 57 Pages: 181-183
- NAID
  10029583829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] 糖尿病領域における遺伝カウンセリング-現状と今後の課題2010
- Author(s)
  岩崎直子
- Journal Title
  
  医学のあゆみ
  
  Volume: 232 Pages: 1217-1218
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus.2010
- Author(s)
  Okamoto K, Iwasaki N, Nishimura C, Doi K, Noiri E, et al.
- Journal Title
  
  American Journal of Human Genetics
  
  Volume: 86 Pages: 54-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Journal Article] Impact of variants in the VEGF gene on progression of proliferative diabetic retinopathy2008
- Author(s)
  Nakamura S, Iwasaki N, Funatsu H, Kitano S, Iwamoto Y.
- Journal Title
  
  Graefes Arch Clin Exp Opthalmol 247
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590338
[Journal Article] Impact of variants in the VEGF gene on progression of proliferative diabetic retinopathy2008
- Author(s)
  Nakamura S, Iwasaki N, Funatsu H, Kitano S, Iwamoto Y
- Journal Title
  
  Graefes Arch Clin Exp Opthalmol 247
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590338
[Journal Article] Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects2008
- Author(s)
  Kazuaki Miyake, Yukio Horikawa, Naoko Iwasaki, et. al.
- Journal Title
  
  Journal of Human Genetics 53
  
  Pages: 174-180
- NAID
  10021248002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590338
[Journal Article] Multistage genone-wide SNP association study revealed KCNQ1 as a novel susceptibility gene for type 2 diabetes mellitus in multiple ethnic groups : a report of the Millennium Genome Project of Japan2008
- Author(s)
  Yasuda K, Miyake K, Hoikawa Y, Iwasaki N, Iwamoto Y, Makino H, Nanjo K, Kadowaki T, et al.
- Journal Title
  
  Nature Genet 40
  
  Pages: 1092-1097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590338
[Journal Article] Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan2008
- Author(s)
  Horikawa Y, Miyake K, Yasuda K, Enya M, Horita Y, Iwasaki N, Iwamoto Y, et al
- Journal Title
  
  J Clin Endoclinol Metab 93
  
  Pages: 3136-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590338
[Journal Article] Multistage genome-wide SNP association study revealed KCNQ1 as a novel susceptibility gene for type 2 diabetes mellitus in multiple ethnic groups : a report of the Millennium Genome Project of Japan2008
- Author(s)
  Yasuda K, Iwasaki N, et.al.
- Journal Title
  
  Nature Genet 40
  
  Pages: 1092-1097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590338
[Journal Article] Association of TCF7L2 polymorphisms with susceptibility to type2 diabetes in 4, 087 Japanese subjects2008
- Author(s)
  Miyake K, Horikawa Y, Hara K, Yasuda K, Osawa H, Furuta H, Yamagata K, Hinokio Y, Iwasaki N, Iwamoto Y, et al.
- Journal Title
  
  J Hum Genet 53
  
  Pages: 174-180
- NAID
  10021248002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590338
[Journal Article] Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan2008
- Author(s)
  Horikawa Y, Iwasaki N, et.al.
- Journal Title
  
  J Clin Endoclinol Metab 93(8)
  
  Pages: 3136-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590338
[Journal Article] Genetic variants in the caplan-10 gene and the development of type 2 diabetes in the Japanese population.2005
- Author(s)
  Naoko Iwasaki, Makiko Ogata et al.
- Journal Title
  
  J Hum Genet 50
  
  Pages: 92-98
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590957
[Journal Article] Genetic variants in the caplan-10 gene and the development of type 2 diabetes in the Japanese population.2005
- Author(s)
  Naoko Iwasaki, Yukio Horikawsa, Takafumi Tsuchiya, Yutaka Kitamura, Takahiro Nakamura, Yukio Tanizawa, Makiko Ogata, Naoyuki Kamatani, yasuhiko Iwamoto, Laura del Bosque-Plata, M.Geoffrey Hayes, Nancy J.Cox, Graeme I.Bell
- Journal Title
  
  J.Hum.Genet. 50
  
  Pages: 92-98
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590957
[Journal Article] Genetic variants in the Calpain-10 gene and the development of type2 diabetes in the Japanese population2005
- Author(s)
  Iwasaki N et al.
- Journal Title
  
  J.Hum.Genetics (in press)
- NAID
  10014513339
- Data Source
  KAKENHI-PROJECT-16012261
[Journal Article] 2型糖尿病の疾患感受性遺伝子2004
- Author(s)
  岩崎直子
- Journal Title
  
  Mebio 21(6)
  
  Pages: 22-27
- Data Source
  KAKENHI-PROJECT-16012261
[Journal Article] 連鎖解析を用いた2型糖尿病の全ゲノム解析による日本人糖尿病遺伝素図2004
- Author(s)
  岩崎直子
- Journal Title
  
  内分泌・糖尿病科 18(1)
  
  Pages: 64-71
- Data Source
  KAKENHI-PROJECT-16012261
[Journal Article] 2型糖尿病感受性遺伝子-罹患同胞対解析2004
- Author(s)
  岩崎直子
- Journal Title
  
  医学のあゆみ「別冊」
  
  Pages: 185-187
- Data Source
  KAKENHI-PROJECT-16012261
[Journal Article] Simultenuous estimation of haplotype frequencies and quantitative trait parameters: applications to the test of assocation between phenotype and diplotype configuration2004
- Author(s)
  Iwasaki, N他
- Journal Title
  
  Genetics 168
  
  Pages: 525-539
- Data Source
  KAKENHI-PROJECT-16012261
[Journal Article] 2型糖尿病感受性遺伝子のホールゲノムアプローチ2004
- Author(s)
  岩崎直子
- Journal Title
  
  分子糖尿病学の進歩2004
  
  Pages: 68-74
- Data Source
  KAKENHI-PROJECT-16012261
[Journal Article] Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects
- Author(s)
  Miyake K, Iwasaki N, et.al.
- Journal Title
  
  J Hum Genet
- NAID
  10021248002
- Data Source
  KAKENHI-PROJECT-19590338
[Journal Article] correspoding author) Lanosterol synthase predisposes to type 2 diabetes mellitus and insulin resistance.
- Author(s)
  Okamoto K, Honda K, Iwasaki N*, TokunagaK et al.
- Journal Title
  
  Hum Mol Genet (in revising)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510214
[Patent] 糖尿病発症及び/又は進展リスクの判定方法2008
- Inventor(s)
  徳永勝士岩崎直子岡本好司鎌谷直之
- Industrial Property Rights Holder
  徳永勝士岩崎直子岡本好司鎌谷直之
- Industrial Property Number
  2008-316595
- Filing Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] Systematic Genetic Analysis achieved 57.1% of detection rate in Japanese MODY patient2024
- Author(s)
  Satoshi Tanaka, Naoko Iwasaki
- Organizer
  GGD Conference Exeter 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] Whole Exome Sequencing revealed a novel PDX1 missense variants Arg148Leu in Japanese MODY4 patients2024
- Author(s)
  Satoshi Tanaka, Hiroyuki Akagawa, Naoko Iwasaki
- Organizer
  第69回日本人類遺伝学会大会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] Current status of genetic counseling for MODY in our hospital2024
- Author(s)
  Yuko Sato, Naoko Iwasaki, Satoshi Tanaka, Mari Urano, Toshiyuki Yamamoto, Kayoko Saito
- Organizer
  第69回日本人類遺伝学会大会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] Systematic Genetic Analysis achieved 57.1% of detection rate in Japanese MODY patient.2024
- Author(s)
  Satoshi Tanaka, Hiroyuki Akagawa, Naoko Iwasaki
- Organizer
  9th Meeting of the Study Group on Genetics of Diabetes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] Next Generation Sequencing in Japanese patients with Maturity-Onset Diabetes of the Young.2023
- Author(s)
  Satoshi Tanaka,. Naoko Iwasaki, Kenko Azuma, Hiroyuki Akagawa, Shohei Mitani
- Organizer
  Human Genectics Asia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] Current issues in the management of monogenic diabetes in our institution2023
- Author(s)
  Naoko Iwasaki
- Organizer
  IDF-WPR Congress 2023 / 15th Scientific Meeting of AASD
- Invited
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] 糖尿病のprecision medicineを目指してーＭODYの診断による患者QOL向上のためにー2022
- Author(s)
  岩崎直子
- Organizer
  第56回　糖尿病学の進歩
- Invited
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] MODY5疑い症例のスクリーニングにより同定された15例のMODY5症例におけるgenotype-phenotypeの検討2022
- Author(s)
  岩崎直子, 田中　慧, 赤川浩之, 尾形真規子, 井出理沙, 馬場園哲也, 齋藤加代子
- Organizer
  第65回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] Outcome of Providing the Precision Medicine in Patients with Monogenic Diabetes2022
- Author(s)
  Tanaka Satoshi, Iwasaki Naoko,
- Organizer
  American College of Physicians Japan Chapter 年次総会・講演会　2022
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] ＜シンポジウム⑥ 予防に活かす　最新の臨床研究の成果＞糖尿病治療における個別化医療の重要性2022
- Author(s)
  岩崎直子
- Organizer
  第60回日本糖尿病学会　九州地方会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] 次世代シークエンサーを用いたMonogenic diabetesのスクリーニング2022
- Author(s)
  岩崎直子, 田中慧, 赤川浩之
- Organizer
  日本人類遺伝学会第67回大会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] シンポジウム8「糖尿病および合併症の遺伝素因」　単一遺伝子異常による糖尿病の個別化医療に向けた展望2022
- Author(s)
  岩崎直子
- Organizer
  第37回日本糖尿病合併症学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] Genetic screening for monogenic diabetes using whole exome sequencing in a single hospital cohort in Japan2022
- Author(s)
  Tanaka Satoshi, Akagawa Hiroyuki, Ogata Makiko, Iwasaki Naoko
- Organizer
  58th European Association for the Study of Diabetes Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] 日本人MODY1患者の全エクソームシーケンシング解析2022
- Author(s)
  田中慧, 赤川浩之, 岩崎直子
- Organizer
  日本人類遺伝学会第67回大会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] 成人期に診断された新規バリアントによるMODY2の姉妹例2022
- Author(s)
  田中　慧、赤川浩之、馬場園哲也、岩崎直子
- Organizer
  第65回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] 全エクソームシーケンシングによるMODY27症例の網羅的遺伝子解析2021
- Author(s)
  岩崎直子、赤川浩之、長谷美智代、尾形真規子、斎藤加代子
- Organizer
  第64回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] 全エクソームシークエンスによるMODY遺伝子のゲノム構造異常の解析2021
- Author(s)
  岩崎直子, 赤川浩之, 東剣虹
- Organizer
  日本人類遺伝学会　第66回大会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] WFS1遺伝子における新規複合ヘテロ接合性変異を認めたWolfram症候群の一例2021
- Author(s)
  氏家　淳、原澤　彰、三宅勇輝、奥村武憲、久保未央、古川　翔、原　健司、阿久澤有、篠﨑浩之、山内元貴、土屋天文、竹林晃三、岩崎直子、橋本貢士
- Organizer
  第64回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] Progeroid syndrome with focal segmental glomeruloscrelosis due to ZMPSTE24 mutations2019
- Author(s)
  Mari Matsuo, Naoko Iwasaki, Toru Kusakabe, Kayoko Sato, Gen Nishimura, Kayoko Saito
- Organizer
  European Human Genetics Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07258
[Presentation] Screening for mutations in 14 kinds of MODY genes in patients with MODY in Japanese by next generation sequencing2018
- Author(s)
  Naoko Iwasaki, Toshiyuki Yamamoto, Hiroyuki Akagawa, makiko Ogata, Kayoko Saito
- Organizer
  Annual meeting of Japan Sosiety of Human Genetics 63rd Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07258
[Presentation] Screening for mutations in 14 kinds of MODY genes in patients with MODY in Japanese by next generation sequencing2018
- Author(s)
  Naoko Iwasaki, Toshiyuki Yamamoto, Hiroyuki Akagawa, makiko Ogata, Kayoko Saito
- Organizer
  The American Society of Human Genetics 2018 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07258
[Presentation] Newly identified mutation in 5'UTR of HNF4A in a case of MODY32017
- Author(s)
  Yukari Kiramura,Iwasaki Naoko, Ogata Makiko, AKAGAWA HIROYUKI, Saito Kayoko, YASUKO UCHIGATA
- Organizer
  The 9th Scientific Meeting of the Asian Associaation for the Study of Diabetes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07258
[Presentation] A novel mutation in the IPF-1/PDX-1 gene identified in a Japanese family with MODY.2017
- Author(s)
  IwasakiNaoko, AKAGAWA HIROYUKI, Hase Michiyo, FUJIMAKI Risa, Furukawa Toru, MITANI Shohei, UCHIGATA YASUKO
- Organizer
  53rd Annual Meeting of the European Association for the Study of Diabetes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07258
[Presentation] A novel mutation in the IPF-1/PDX-1 gene identified in a Japanese family with MODY.2017
- Author(s)
  Iwasaki Naoko, Akagawa Hiroyuki, Hase Michiyo, Takizawa Miho, Ogata Makiko, Babazono Tetsuya
- Organizer
  日本人類遺伝学会第62回大会
- Data Source
  KAKENHI-PROJECT-17K07258
[Presentation] Application of MODY Probability Calculator for Japanese Patients with MODY32013
- Author(s)
  Naoko Iwasaki, Miho Takizawa, Risa Ide, Makiko Ogata, Yasuko Uchigata
- Organizer
  56rd Annual Meeting of Scientific Session of American Association of Diabetes
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Identification of MODY-X gene in Japanese by combination of whole exome sequencing with linkage analysis.2012
- Author(s)
  Iwasaki N, Saito A, et al
- Organizer
  9th International Diabetes Federation Western Pacific Region Congress
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] 次世代シークエンサーを用いた新規 MODY遺伝子の解析2012
- Author(s)
  岩崎直子、斎藤聡、他
- Organizer
  第55回日本糖尿病学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Whole exome sequencing identifiesCUL9 as a MODY-X gene2012
- Author(s)
  Iwasaki Naoko, Akira Saito, Ogata Makiko, Furukawa Toru, Takizawa Miho, FUJIMAKI Risa, Uchigata Yasuko
- Organizer
  European Association for the Study of Dabetes 48th Annual Meeting
- Place of Presentation
  Berlin, Gemany
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Liragultide Ameriorate the ethdium bromide induced mitochondrial dysfunction of cultured b-cell which are the model of MIDD2012
- Author(s)
  Ogata Makiko, Iwasaki Naoko, Fujimaki Risa, Takizawa Miho, Uchigata Yasuko
- Organizer
  9th International Diabetes federation Western Pacific Region Congress
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] MODY1、MIDD モデル培養膵β細胞においてリラグルチドはミトコンドリア機能を回復させる2012
- Author(s)
  尾形真規子、岩崎直子、他
- Organizer
  第55回日本糖尿病学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] MODY1原因遺伝子hepatocyte nuclear factor(HNF)-4αのC端部欠損の影響2012
- Author(s)
  尾形真規子, 岩崎直子, 藤巻理沙, 滝澤美保, 内潟安子
- Organizer
  第52回日本先天異常学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Identification of MODY-X gene in Japanese by combination of whole exome sequencing with linkage analysis2012
- Author(s)
  Iwasaki N,Iwasaki Naoko, Saito Akira, Furukawa Toru, Takizawa Miho, Fujimaki Risa, Ogata Makiko, Uchigata Yasuko
- Organizer
  9ｔｈ International Diabetes federation Western Pacific Region Congress
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Application of MODYprobability calculator for Japanese patients with MODY2012
- Author(s)
  Iwasaki N, Takizawa M, ide R, Ogata M, Uchigata Y.
- Organizer
  73th scientific session of American Diabetes Assoc
- Place of Presentation
  Chicago
- Year and Date
  2012-06-22
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] MODY5 診断における表現型の有用性と遺伝子型の関連について2012
- Author(s)
  藤巻理沙、滝沢美保、岩崎直子、他
- Organizer
  第55回日本糖尿病学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Whole exome sequence identifies CUL9 as a MODY-X gene2012
- Author(s)
  Iwasaki N, Saito A
- Organizer
  48rd Annual Meeting of EADSD (European Association for Study of Diabetes)
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] MODY および若年発症糖尿病を対象としたインスリン遺伝子変異の検索2011
- Author(s)
  岩崎直子、滝澤美保、藤巻理沙、中村新子、尾形真規子、富岡光枝、岩本安彦
- Organizer
  第54回日本糖尿病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Common variation in lanosterol synthase gene predispose to type 2 diabetes.2011
- Author(s)
  Iwasaki N, Okamoto K, et al.
- Organizer
  47rd Annual Meeting of EADSD (European Association for Study of Diabetes)
- Place of Presentation
  Risbon, Portogal
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] KATP channel and mitochondrial pH: Estimation of mitochondrial matrix pH in cultured living β cells using an improved ratiometric biosensor2011
- Author(s)
  Ogata M, Iwasaki N, et al.
- Organizer
  47rd Annual Meeting of EADSD (European Association for Study of Diabetes)
- Place of Presentation
  Risbon, Portogl
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] MODY および若年発症糖尿病を対象としたインスリン遺伝子変異の検索2011
- Author(s)
  岩崎直子、滝澤美保、藤巻理沙、中村新子、尾形真規子、富岡光枝、岩本安彦
- Organizer
  第56回日本人類遺伝学会
- Place of Presentation
  千葉
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] 膵β細胞ミトコンドリア pH は電子伝達系コンプレックスの活性バランスによって決定される2011
- Author(s)
  尾形真規子、岩崎直子、他
- Organizer
  第54回日本糖尿病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] MODYおよび若年発症糖尿病を対象としたインスリン遺伝子変異の検索2011
- Author(s)
  岩崎直子、滝澤美保、藤巻理沙、中村新子、尾形真規子、富岡光枝、岩本安彦
- Organizer
  第56回日本人類遺伝学会
- Place of Presentation
  千葉
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] ミトコンドリア遺伝子異常に伴う糖尿病の予後2011
- Author(s)
  滝澤美保、岩崎直子、藤巻理沙、尾形真規子、富岡光枝、岩本安彦
- Organizer
  第54回日本糖尿病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] 膵β細胞ミトコンドリアpHは電子伝達系コンプレックスの活性バランスによって決定される2011
- Author(s)
  尾形真規子、岩崎直子、淡路健雄、藤巻理沙、富岡光枝、丸山敬、岩本安彦
- Organizer
  第54回日本糖尿病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Identification of KCNJ15 as a susceptibility gene in in Asian patients with Type 2 diabetes Mellitus2011
- Author(s)
  Iwasaki N
- Organizer
  16thJapan-Korea Symposium on Diabetes Mellitus
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] 内臓脂肪蓄積のある糖尿病合併脂質異常症におけるコレスチラミドの有効性(第2報)2011
- Author(s)
  藤巻理沙、岩崎直子、他
- Organizer
  第54回日本糖尿病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Common variation in lanosterol synthase gene predispose to type 2 diabetes2011
- Author(s)
  Iwasaki N, Okamoto K, Noiri E, Takizawa M, Fujimaki R, Ogata M, Hansen T, Pedersen O, Part K, Iwamoto Y, Tokunaga K
- Organizer
  47 rd Annual Meeting of European Association for Study of Diabetes
- Place of Presentation
  Risbon, Portogal
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Identification of KCNJ15 as a susceptibility gene in in Asian patients with Type 2 diabetes Mellitus2011
- Author(s)
  Iwasaki N
- Organizer
  16^<th> Japan-Korea Symposium on Diabetes Mellitus
- Place of Presentation
  Tokyo(招待講演)
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] KATP channel and mitochondrial pH : Estimation of mitochondrial matrix pH in cultured living beta cell using an improved ratiometric biosensor2011
- Author(s)
  Ogata M, Iwasaki N, Awaji T, Fujimaki R, Takizawa M, Maruyama K, Iwamoto Y
- Organizer
  47 rd Annual Meeting of European Association for Study of Diabetes
- Place of Presentation
  Risbon, Portogal
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] MODYおよび若年発症糖尿病を対象としたインスリン遺伝子変異の検索2011
- Author(s)
  岩崎直子、滝澤美保、藤巻理沙、中村新子、尾形真規子、富岡光枝、岩本安彦
- Organizer
  第54回日本糖尿病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] 糖尿病治療薬およびQ268XHNF4α遺伝子導入による培養膵β細胞ミトコンドリア電子伝達系機能への影響2010
- Author(s)
  尾形真規子、岩崎直子、藤巻理沙、富岡光枝、岩本安彦
- Organizer
  第53回日本糖尿病学会総会
- Place of Presentation
  岡山市
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Positional cloningによって見出された新規2型糖尿病感受性遺伝子KCNJ15の白人2型糖尿病における意義2010
- Author(s)
  岩崎直子、尾形真規子、藤巻理沙、富岡光枝、岩本安彦
- Organizer
  第53回日本糖尿病学会総会
- Place of Presentation
  岡山市
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Genetic counseling for MODY, MIDD and other type of diabetes mellitus2010
- Author(s)
  Iwasaki N, Takizawa M, Fujimaki R, Ogata M, Saito K, Iwamoto Y
- Organizer
  46rd Annual Meeting of EASD (European Association for Study of Diabetes)
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Mutation of HNF4a/MODY1 (Q268XHNF4a) gene affects the mitochondrial function in cultured living b cells; evaluation by a new original system2010
- Author(s)
  Ogata M, Iwasaki N, Awaji T, Fujimaki R, Takizawa M, Iwamoto Y
- Organizer
  14th International Congress of Endocrinology
- Year and Date
  2010-04-01
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] 動脈硬化関連遺伝子多型と糖尿病網膜症の関連2010
- Author(s)
  中村新子、岩崎直子、尾形真規子、北野滋彦、岩本安彦
- Organizer
  第53回日本糖尿病学会総会
- Place of Presentation
  岡山市
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Positional cloning によって見出された新規 2 型糖尿病感受性遺伝子 KCNJ15 の白人 2型糖尿病における意義2010
- Author(s)
  岩崎直子, 岡本好司, 野入英世, 尾形真規子,鎌谷直之, 徳永勝士, Pedersen O, 岩本安彦
- Organizer
  第53回日本糖尿病学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] Genetic counseling for MODY, MIDD and other type of diabetes mellitus.2010
- Author(s)
  Iwasaki N, Takizawa M, Fujimaki R, Ogata M, Saito K, Iwamoto Y
- Organizer
  46 rd Annual Meeting of European Association for Study of Diabetes (EASD)
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] MODY原因遺伝子領域におけるゲノム構造異常の解析2010
- Author(s)
  滝澤美保、岩崎直子、藤巻理沙、富岡光枝、岩本安彦
- Organizer
  第53回日本糖尿病学会総会
- Place of Presentation
  岡山市
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-22510214
[Presentation] A novel susceptible gene to type 2 diabetes on chromosome 21 as a new target for the treatment2009
- Author(s)
  Iwasaki N, Okamoto K, Takizawa M, Ogata M, et.al.
- Organizer
  The 2nd European Association for the Study of Diabetes - Study Group for Genetics of Diabetes Meeting
- Place of Presentation
  Bergen, Norway
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] 培養膵β細胞を用いたミトコンドリア機能の継時的定量評価の検討2008
- Author(s)
  尾形真規子, 淡路健雄, 岩崎直子, 富岡光枝, 苅部幸代, 宮崎俊一, 岩本安彦
- Organizer
  第51回日本糖尿病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] Deletion of the whole gene deletion mutation of the HNF-1・gene in Japanese Patients with MODY2008
- Author(s)
  Iwasaki N, Yamamoto T, Watanabe J, et.al.
- Organizer
  44rd Annual Meeting of European Association for Study of Diabetes
- Place of Presentation
  Roma
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] メトフォルミンの治療効果とOrganidc Cation Transporter-1遺伝子多型の関連2008
- Author(s)
  滝沢美保, 岩崎直子, 藤巻理沙, 尾形真規子, 富岡光枝, 吉永陽子, 岩本安彦
- Organizer
  第51回日本糖尿病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] Deletion of the whole gene deletion mutation of the HNF-1β gene in Japanese Patients with MODY2008
- Author(s)
  Iwasaki N, Yamamoto T, Watanabe J, Ogata M, Takizawa M, Iwamoto Y
- Organizer
  44rd Annual Meeting of European Association for Study of Diabetes
- Place of Presentation
  Rome, Italy
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] Hepatocyte nuclear factor-1β遺伝子欠損を認めたM0DY52008
- Author(s)
  岩崎直子, 尾形真規子, 藤巻理沙, 滝澤美保, 岩本安彦
- Organizer
  日本人類遺伝学会第53回大会
- Place of Presentation
  横浜
- Year and Date
  2008-09-30
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] 抗酸化作用に関連するMn-SOD遺伝子V16A多型と糖尿病網膜症の検討2008
- Author(s)
  中村新子, 岩崎直子, 尾形真規子, 北野滋彦, 岩本安彦
- Organizer
  第51回日本糖尿病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] Hepatocyte nuclear factor- 1β遺伝子欠損を認めたM0DY52008
- Author(s)
  岩崎直子, 尾形真規子, 藤巻理沙, 滝澤美保, 岩本安彦
- Organizer
  第51回日本糖尿病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] OCT-1遺伝子多型によるメトフォルミン感受性2008
- Author(s)
  滝澤美保, 岩崎直子, 尾形真規子, 山本俊至, 岩本安彦
- Organizer
  日本人類遺伝学会第53回大会
- Place of Presentation
  横浜
- Year and Date
  2008-09-30
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] Q268X, truncated mutant of HNF-4a causing MODY1, hasnucleus-targeting ability and can bind with wild-type HNF-4a or its repressor SHP abd accumulate them to the nucleus in cultured cells2008
- Author(s)
  Ogata M, Awaji T, Iwasaki N, Bell GI, Miyazaki S, Iwamoto Y
- Organizer
  44rd Annual Meeting of European Association for Study of Diabetes
- Place of Presentation
  Rome, Italy
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] Hepatocyte nuclear factor-1β遺伝子欠損を認めたMODY52007
- Author(s)
  岩崎直子, 他
- Organizer
  日本人類遺伝学会第52回大会
- Place of Presentation
  東京
- Year and Date
  2007-09-14
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] 糖尿病網膜症に関与するVEGF遺伝子多型を有する症例の予後調査2007
- Author(s)
  中村新子、岩崎直子、他
- Organizer
  第50日本糖尿病学会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] Association study based on the genome wide linkage results revealed two genes on chromosome 21 in type 2 diabetic subjects in Japanese2007
- Author(s)
  Naoko Iwasaki, et. al.
- Organizer
  67th American Diabetes Association Annual Meeting Scientific Session
- Place of Presentation
  Chicago, USA
- Year and Date
  2007-06-22
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] 関連解析によって得られた21番染色体上の2型糖尿病感受性遺伝子2007
- Author(s)
  岡本好司、岩崎直子、他
- Organizer
  第50日本糖尿病学会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] HNF4α変異蛋白の生細胞内機能の検討2007
- Author(s)
  尾形真規子、岩崎直子、他
- Organizer
  第50日本糖尿病学会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] 2型糖尿病におけるMafA遺伝子多型の検討2007
- Author(s)
  岩崎直子, 他
- Organizer
  第50日本糖尿病学会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] Detection of genomic rearrangements of MODY gene in Japanese patient
- Author(s)
  Takizawa M, Iwasaki N, Yamamoto T, et.al
- Organizer
  2)と同一の学会
- Data Source
  KAKENHI-PROJECT-19590338
[Presentation] Q268X, truncated mutant of HNF-4a causing MODY1, has nucleus-targeting ability and can bind with wild-type HNF-4a or its repressor SHP and accumulate them to the nucleus in cultured cells
- Author(s)
  Ogata M, Awaji T, Iwasaki N, Bell GI, Miyazaki S, Iwamoto Y
- Organizer
  5)と同一の学会
- Data Source
  KAKENHI-PROJECT-19590338

1. OGATA Makiko (10233404)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. AWAJI Takeo (60297546)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. IWAMOTO Yasuhiko (60143434)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KITANO Shigehiko (30161483)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 赤川浩之 (60398807)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
6. NAKANISHI Toshio (90120013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SUKURA Hiroshi (70240710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 鎌谷直之 (00114447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 河村真規子

# of Collaborated Projects: 0 results

# of Collaborated Products: 32 results

iwasaki naoko 岩崎 直子

Iwasaki Naoko 岩崎 直子

IWASAKI Naoko 岩崎 直子

Research Projects

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A comprehensive genomic investigation of monogenic diabetes via whole-genome sequencingPrincipal Investigator

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A comprehensive genomic investigation of monogenic diabetes via whole-genome sequencingPrincipal Investigator

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Complihensive analysis for causative genes in unknown monogenic diabetesPrincipal Investigator

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Searching for the causative genes and susceptibility SNPs for diabetes mellitus based on the linkage analysis dataPrincipal Investigator

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Study for the Genetics of diabetes mellitus and its complications with one large hospital based cohortPrincipal Investigator

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全ゲノム解析結果に基づいた2型糖尿病候補遺伝子解析と糖尿病網膜症関連遺伝子の解析Principal Investigator

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全ゲノム解析結果に基づいた2型糖尿病候補遺伝子の解析と糖尿病網膜症関連遺伝子の解析Principal Investigator

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Mithochondrial pH in virtal inslinoma cell line INS-1 with glucose stimulant Ca release

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日本人2型糖尿病原因遺伝子の全ゲノム解析結果に基づいた2型糖尿病候補遺伝子の検討Principal Investigator

Principal Investigator

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日本人2型糖尿病原因遺伝子の全ゲノムレベル解析とクローニングPrincipal Investigator

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Study for onset of MODY, by gene mutation of transcriptional factor, using cellular localization

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日本人2型糖尿病原因遺伝子の全ゲノムレベル解析Principal Investigator

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インスリン感受性からみたインスリン非依存型糖尿病の成因に関する遺伝学的研究

Principal Investigator

iwasaki naoko 岩崎直子

Iwasaki Naoko 岩崎直子

IWASAKI Naoko 岩崎直子

[Book] 遺伝医学　朝倉内科学　12版2022

[Book] 糖尿病ナビゲーター第2版門脇孝編第2章 20.MODY pp144-1452010

[Book] 2型糖尿病遺伝子 p311-314「カラー版糖尿病学基礎と臨床」2007