YOSHIDA Tomoaki 吉田友昭

Researcher Number	70210705
Other IDs
External Links
Affiliation (Current)	2022: 藤田医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	1998 – 2005: 愛知医科大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Bacteriology (including Mycology)
Keywords	Principal Investigator 腸管出血性大腸菌 / 志賀毒素 / アポトーシス / Caspase / 大腸上皮細胞 / 細胞内侵入 / 細胞内感染 / インティミン / type III分泌 / Colon epithelial cells … More / Lactobacillus / 血管内皮 / 溶血性尿毒症症候群 / インターフェロン / ヴェロ毒素 / Shiga toxin ; / Vascular endothelium ; / Apoptosis ; / Hemolytic uremic syndrome ; / Enterohemorrhagic E.Coli ; / Inteerferon ; / type III分泌システム / 細胞骨格 / typeIII分泌 / Enterohemorrhagic E. coli / Intracelluar invasion / Type 3 secretion / Cytoskeleton / probiotics / flagellin / フラジェリン / プロテオーム / Probiotics / Enterohemorrhagic Escherichia coli / Invasion into host cells / Probiotic / Flagellin / Two hybrid法 / 細胞内輸送 / 蛋白相互作用 / cDNA subtraction / Shiga toxin / Two hybrid analysis / Intracellular trafficking / Apoptosis / Protein interaction Less

Research Projects
(4 results)
Research Products
(17 results)

Systematic analysis on the molecular mechanism of Shiga-toxin cytotoxicityPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Tomoaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University
Comprehensive analysis of bacterial factors involved in enterohemorrhagic E. coli infection to human colon epithelial cells for a preventive approachPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Tomoaki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University
Infection mechanism of E.coli 0157 to native human colon epithelial cellsPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Tomoaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University
How do the primary cultures of human umblical endothelium become resistant to vero toxins ?Principal Investigator
- Principal Investigator
  
  YOSHIDA Tomoaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University

All 2006 2005 2004 Other

All Journal Article

[Journal Article] Lethal endotoxic shock using alpha-galactosylceramide sensitization as a new experimental model of septic shock.2006
- Author(s)
  Ito H, Koide N, Hassan F, Islam S, Tumurkhuu G, Mori I, Yoshida T, Kakumu S, Moriwaki H, Yokochi T.
- Journal Title
  
  Lab Invest. 86(3)
  
  Pages: 254-261
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] Chlamydia pneumoniae infection enhances lectin-like oxidized low-density lipoprotein receptor (LOX-1) expression on human endothelial cells2006
- Author(s)
  Yoshida T, Koide N, Mori I, Ito H, Yokochi T
- Journal Title
  
  FEMS Microbiol.Let. (In press)
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] Lipopolysaccharide prevents apoptosis induced by brefeldin A, an endoplasmic reticulum stress agent, in RAW 264.7 cells.2006
- Author(s)
  Islam S, Hassan F, Tumurkhuu G, Ito H, Koide N, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  Biochem Biophys Res Commun. 340
  
  Pages: 589-596
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] Lipopolysaccharide prevents apoptosis induced by brefeldin A, and endoplasmic reticulum stress agent, in RAW 264.7 cells.2006
- Author(s)
  Islam S, Hassan F, Tumurkhuu G, Ito H, Koide N, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  Biochem Biophys Res Commun. 340(2)
  
  Pages: 589-596
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] Lipopolysaccharide prevents apoptosis induced by brefeldin A, and endoplasmic reticulum stress agent, in RAW 264.7 cells.2006
- Author(s)
  Islam S, Hassan F, Tumurkhuu G, Ito H, Koide N, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  Biochem Biophys Res Commun. 340
  
  Pages: 589-96
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] Chlamydia pneumoniae infection enhances lectin-like oxidized low-density lipoprotein receptor (LOX-1) expression on human endothelial cells2006
- Author(s)
  Yoshida T, Koide N, Mori I, Iro H, Yokochi T
- Journal Title
  
  FEMS Microbiol. Let. (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] Lethal endotoxic shock using alpha-galactosylceramide sensitization as a new experimental model of septic shock.2006
- Author(s)
  Ito H, Koide N, Hassan F, Islam S, Tumurkhuu G, Mori I, Yoshida T, Kakumu S, Moriwaki H, Yokochi T.
- Journal Title
  
  Lab Invest. 86
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] A Quantitative Analysis of Cedar Pollen Specific Immunoglobulins in Nasal Lavage Supported the Local Production of Specific IgE, Not of Specific IgG2005
- Author(s)
  Yoshida T, Usui A, Kusumi T, Inafuku S, Sugiyama T, Koide N, Yokochi T.
- Journal Title
  
  Microbiol.Immunol (In press)
- NAID
  10016132186
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] A quantitative analysis of cedar pollen-specific immunoglobulins in nasal lavage supported the local production of specific IgE, not of specific IgG.2005
- Author(s)
  Yoshida T, Usui A, Kusumi T, Inafuku S, Sugiyama T, Koide N, Yokochi T.
- Journal Title
  
  Microbiol Immunol. 49
- NAID
  10016132186
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] A quantitative analysis of cedar pollen-specific immunoglobulins in nasal lavage supported the local production of specific IgE, not of specific IgG.2005
- Author(s)
  Yoshida T, Usui A, Kusumi T, Inafuku S, Sugiyama T, Koide N, Yokochi T.
- Journal Title
  
  Microbiol Immunol. 49(6)
  
  Pages: 529-534
- NAID
  10016132186
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] Butyrate enhances the production of nitric oxide in mouse vascular endothelial cells in response to gamma interferon.2004
- Author(s)
  Morikawa A, Sugiyama T, Koide N, Mori I, Mu MM, Yoshida T, Hassan F, Islam S Yokochi T.
- Journal Title
  
  J.Endotoxin Res. 10
  
  Pages: 32-38
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] The enhancing action of D-galactosamine on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells.2004
- Author(s)
  Morikawa A, Koide N, Sugiyama T, Mu MM, Hassan F, Islam S, Ito H, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  FEMS Immunol Med Microbiol. 41(3)
  
  Pages: 211-218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] 2-aminopurine inhibits lipopolysaccharide-induced nitric oxide production by preventing IFN-beta production.2004
- Author(s)
  Sugiyama T, Fujita M, Koide N, Mori I, Yoshida T, Mori H, Yokochi T.
- Journal Title
  
  Microbiol.Immunol 48
  
  Pages: 957-963
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] Butyrate enhances the production of nitric oxide in mouse vascular endothelial cells in response to gamma interferon.2004
- Author(s)
  Morikawa A, Sugiyama T, Koide N, Mori I, Mu MM, Yoshida T, Hassan F, Iaslam S, Yokochi T.
- Journal Title
  
  J. Endotoxin Res. 10
  
  Pages: 32-8
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] 2-aminopurine inhibits lipopolysaccharide-induced nitric oxide production by preventing IFBN-beta production.2004
- Author(s)
  Sugiyama T, Fujita M, Koide N, Mori I, Yoshida T, Mori H, Yokochi T.
- Journal Title
  
  Microbiol. Immunol 48
  
  Pages: 957-63
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] 2-aminopurine inhibits lipoploysaccharide-induced nitric oxide production by preventing IFN-beta production.2004
- Author(s)
  Sugiyama T, Fujita M, Koide N, Mori I, Yoshida T, Mori H, Yokochi T.
- Journal Title
  
  Micorbiol Immunol. 48(12)
  
  Pages: 957-963
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590374
[Journal Article] Chlamydia pneumoniae infection enhances lectin-like oxidized low-density lipoprotein receptor (LOX-1) expression on human endothelial cells
- Author(s)
  Yoshida T, Koide N, Mori I, Ito H, Yokochi T
- Journal Title
  
  FEMS Microbiol.Let. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590374

YOSHIDA Tomoaki 吉田 友昭

Research Projects

Research Products

Systematic analysis on the molecular mechanism of Shiga-toxin cytotoxicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analysis of bacterial factors involved in enterohemorrhagic E. coli infection to human colon epithelial cells for a preventive approachPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Infection mechanism of E.coli 0157 to native human colon epithelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

How do the primary cultures of human umblical endothelium become resistant to vero toxins ?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Lethal endotoxic shock using alpha-galactosylceramide sensitization as a new experimental model of septic shock.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Chlamydia pneumoniae infection enhances lectin-like oxidized low-density lipoprotein receptor (LOX-1) expression on human endothelial cells2006

Author(s)

Journal Title

Data Source

[Journal Article] Lipopolysaccharide prevents apoptosis induced by brefeldin A, an endoplasmic reticulum stress agent, in RAW 264.7 cells.2006

Author(s)

Journal Title

Data Source

[Journal Article] Lipopolysaccharide prevents apoptosis induced by brefeldin A, and endoplasmic reticulum stress agent, in RAW 264.7 cells.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Lipopolysaccharide prevents apoptosis induced by brefeldin A, and endoplasmic reticulum stress agent, in RAW 264.7 cells.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Chlamydia pneumoniae infection enhances lectin-like oxidized low-density lipoprotein receptor (LOX-1) expression on human endothelial cells2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Lethal endotoxic shock using alpha-galactosylceramide sensitization as a new experimental model of septic shock.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] A Quantitative Analysis of Cedar Pollen Specific Immunoglobulins in Nasal Lavage Supported the Local Production of Specific IgE, Not of Specific IgG2005

Author(s)

Journal Title

NAID

Data Source

[Journal Article] A quantitative analysis of cedar pollen-specific immunoglobulins in nasal lavage supported the local production of specific IgE, not of specific IgG.2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] A quantitative analysis of cedar pollen-specific immunoglobulins in nasal lavage supported the local production of specific IgE, not of specific IgG.2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Butyrate enhances the production of nitric oxide in mouse vascular endothelial cells in response to gamma interferon.2004

Author(s)

Journal Title

YOSHIDA Tomoaki 吉田友昭